Gene: Nr4a1 (nuclear receptor subfamily 4, group A, member 1) Rattus norvegicus
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Symbol: Nr4a1
Name: nuclear receptor subfamily 4, group A, member 1
Description: ENCODES a protein that exhibits glucocorticoid receptor binding; protein heterodimerization activity; transcription factor binding; INVOLVED IN positive regulation of transcription from RNA polymerase II promoter; regulation of type B pancreatic cell proliferation; apoptotic process (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; ASSOCIATED WITH abnormal renal glomerular filtration; albuminuria; ASSOCIATED WITH blood pressure trait; blood urea nitrogen amount; cholesterol amount; FOUND IN nucleus; cytosol (ortholog); nuclear membrane (ortholog); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HMR; immediate early gene transcription factor NGFI-B; nerve growth factor induced protein I-B; nerve growth factor-induced protein I-B; Ngfi-b; nuclear receptor subfamily 4 group A member 1; Nur77; Orphan nuclear receptor HMR
Orthologs:
Homo sapiens (human) : NR4A1 (nuclear receptor subfamily 4 group A member 1)  HGNC  AGR
Mus musculus (house mouse) : Nr4a1 (nuclear receptor subfamily 4, group A, member 1)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Nr4a1 (nuclear receptor subfamily 4 group A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NR4A1 (nuclear receptor subfamily 4 group A member 1)
Canis lupus familiaris (dog) : NR4A1 (nuclear receptor subfamily 4 group A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr4a1 (nuclear receptor subfamily 4 group A member 1)
more info ...
Allele / Splice: Nr4a1m1Mcwi  
Genetic Models: FHH-Nr4a1m1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07142,899,358 - 142,920,216 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.07140,700,242 - 140,721,073 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.47140,012,807 - 140,020,590 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17140,089,243 - 140,097,024 (+)NCBI
Celera7128,846,928 - 128,854,640 (+)NCBI
Cytogenetic Map7q36NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nr4a1
AGR Gene
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 620029
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE