Gene: Nr4a1 (nuclear receptor subfamily 4, group A, member 1) Rattus norvegicus
Symbol: Nr4a1
Name: nuclear receptor subfamily 4, group A, member 1
Description: ENCODES a protein that exhibits glucocorticoid receptor binding; protein heterodimerization activity; transcription factor binding; INVOLVED IN positive regulation of transcription from RNA polymerase II promoter; regulation of type B pancreatic cell proliferation; apoptotic process (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; ASSOCIATED WITH abnormal renal glomerular filtration; albuminuria; ASSOCIATED WITH blood pressure trait; blood urea nitrogen amount; cholesterol amount; FOUND IN nucleus; cytosol (ortholog); nuclear membrane (ortholog); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HMR; immediate early gene transcription factor NGFI-B; nerve growth factor induced protein I-B; nerve growth factor-induced protein I-B; Ngfi-b; nuclear receptor subfamily 4 group A member 1; Nur77; Orphan nuclear receptor HMR
Homo sapiens (human) : NR4A1 (nuclear receptor subfamily 4 group A member 1)  HGNC
Mus musculus (house mouse) : Nr4a1 (nuclear receptor subfamily 4, group A, member 1)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Nr4a1 (nuclear receptor subfamily 4 group A member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NR4A1 (nuclear receptor subfamily 4 group A member 1)
Canis lupus familiaris (dog) : NR4A1 (nuclear receptor subfamily 4 group A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr4a1 (nuclear receptor subfamily 4 group A member 1)
more info ...
Allele / Splice: Nr4a1m1Mcwi  
Genetic Models: FHH-Nr4a1m1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07142,899,358 - 142,920,216 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.07140,700,242 - 140,721,073 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.47140,012,807 - 140,020,590 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17140,089,243 - 140,097,024 (+)NCBI
Celera7128,846,928 - 128,854,640 (+)NCBI
Cytogenetic Map7q36NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
Experimental Data Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Nr4a1
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 620029
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-06-27
Status: ACTIVE