Gene: Gzmb (granzyme B) Rattus norvegicus
Symbol: Gzmb
Name: granzyme B
Description: ENCODES a protein that exhibits serine-type endopeptidase activity; serine-type peptidase activity (ortholog); INVOLVED IN positive regulation of cell death; positive regulation of necroptotic process; granzyme-mediated apoptotic signaling pathway (ortholog); PARTICIPATES IN allograft rejection pathway; autoimmune thyroid disease pathway; graft-versus-host disease pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); Bronchiolitis Obliterans (ortholog); Pulmonary Disease, Chronic Obstructive (ortholog); FOUND IN early endosome; cytolytic granule (ortholog); cytoplasm (ortholog); INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 17beta-estradiol; 3-chloropropane-1,2-diol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: fragmentin; GLP I; GLP III; GLP-1; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme-like protein 1; granzyme-like protein I; MGC156565; natural killer cell protease 1; RNKP-1
Homo sapiens : GZMB (granzyme B)  HGNC
Mus musculus : Gzmb (granzyme B)  MGI
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01535,413,862 - 35,417,293 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01539,296,950 - 39,300,381 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41535,195,075 - 35,198,506 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11535,211,149 - 35,214,166 (-)NCBI
Celera1529,891,059 - 29,893,786 (-)NCBI
Cytogenetic Map15p12NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gzmb
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 620018
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-08-02
Status: ACTIVE