Gene: Pak2 (p21 (RAC1) activated kinase 2) Rattus norvegicus
Symbol: Pak2
Name: p21 (RAC1) activated kinase 2
Description: ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN cardiac muscle hypertrophy; cellular response to transforming growth factor beta stimulus; cellular response to organic cyclic compound (ortholog); PARTICIPATES IN vascular endothelial growth factor signaling pathway; epidermal growth factor/neuregulin signaling pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH Nephrosis, Puromycin Aminonucleoside; Ureteral Obstruction; Breast Neoplasms (ortholog); FOUND IN secretory granule; INTERACTS WITH 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ortholog); 17alpha-ethynylestradiol (ortholog); 17beta-estradiol (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: gamma-PAK; p21 (CDKN1A)-activated kinase 2; p21 (RAC1) activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 2; p21-activated kinase 2; PAK-2; serine/threonine-protein kinase PAK 2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01172,829,407 - 72,865,815 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01175,895,329 - 75,939,106 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41170,529,961 - 70,588,511 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11170,587,549 - 70,646,100 (+)NCBI
Celera1168,130,464 - 68,189,144 (+)NCBI
Cytogenetic Map11q22NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pak2
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 61953
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2016-08-09
Status: ACTIVE