Gene: Pak1 (p21 (RAC1) activated kinase 1) Rattus norvegicus
Symbol: Pak1
Name: p21 (RAC1) activated kinase 1
Description: ENCODES a protein that exhibits protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; INVOLVED IN cellular response to insulin stimulus; cerebellum development; establishment of cell polarity; PARTICIPATES IN adenosine signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH Acute Lung Injury; Brain Ischemia; brain ischemia; FOUND IN axon; cytosol; dendrite; INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
Also known as: alpha-PAK; p21 (CDKN1A)-activated kinase 1; p21 protein (Cdc42/Rac)-activated kinase 1; p21-activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p68-PAK; PAK-1; protein kinase MUK2; serine/threonine-protein kinase PAK 1
Homo sapiens (human) : PAK1 (p21 (RAC1) activated kinase 1)  HGNC  AGR
Mus musculus (house mouse) : Pak1 (p21 protein (Cdc42/Rac)-activated kinase 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Pak1 (p21 (RAC1) activated kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PAK1 (p21 (RAC1) activated kinase 1)
Canis lupus familiaris (dog) : PAK1 (p21 (RAC1) activated kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pak1 (p21 (RAC1) activated kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01162,768,156 - 162,883,356 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01168,974,734 - 169,090,326 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41155,057,622 - 155,174,714 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11155,136,027 - 155,253,120 (+)NCBI
Celera1150,203,043 - 150,317,598 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pak1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3250
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-14
Status: ACTIVE