Gene: Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1) Rattus norvegicus
Symbol: Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
Description: ENCODES a protein that exhibits 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity; NADP binding; steroid binding; INVOLVED IN cellular response to estradiol stimulus; glucocorticoid biosynthetic process; glucocorticoid catabolic process; PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH Diabetes Mellitus, Type 2; Hyperlipidemias; Metabolic Syndrome X; FOUND IN apical part of cell; cytoplasm; intracellular membrane-bounded organelle; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 11-dehydrocorticosterone; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 11-beta-HSD1; 11-beta-hydroxysteroid dehydrogenase 1; 11-beta-hydroxysteroid dehydrogenase, type 1; 11-DH; 11beta-HSD1; corticosteroid 11-beta-dehydrogenase isozyme 1; cortocosteroid 11-beta dehydrogenase; hydroxysteroid dehydrogenase 11 beta type 1; hydroxysteroid dehydrogenase, 11 beta type 1; LRRGT00065
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.013111,946,626 - 111,996,536 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.013116,502,230 - 116,551,778 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.413109,063,491 - 109,089,468 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113109,252,609 - 109,278,318 (-)NCBI
Celera13104,178,893 - 104,204,865 (-)NCBI
Cytogenetic Map13q27NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hsd11b1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 2834
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-09-13
Status: ACTIVE