Annotation (Toggle Detail/Summary View) Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-nicotine | multiple interactions | ISO | RGD:732432 | 6480464 | Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NUPR1 mRNA]; more ... | CTD | PMID:20230807 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | increases expression | ISO | RGD:732432 | 6480464 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NUPR1 mRNA | CTD | PMID:20230807 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | RGD:732432 | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of NUPR1 mRNA; more ... | CTD | PMID:20230807 | 1-naphthyl isothiocyanate | increases expression | ISO | RGD:736958 | 6480464 | 1-Naphthylisothiocyanate results in increased expression of NUPR1 mRNA | CTD | PMID:17175557 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of NUPR1 mRNA | CTD | PMID:17108234 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of NUPR1 mRNA | CTD | PMID:15576828 | 17beta-estradiol | decreases expression | ISO | RGD:736958 | 6480464 | Estradiol results in decreased expression of NUPR1 mRNA | CTD | PMID:23019147 | 17beta-estradiol | affects expression | ISO | RGD:736958 | 6480464 | Estradiol affects the expression of NUPR1 mRNA | CTD | PMID:23373633 | 1H-pyrazole | increases expression | ISO | RGD:732432 | 6480464 | pyrazole results in increased expression of NUPR1 mRNA | CTD | PMID:17945193 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:736958 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NUPR1 mRNA | CTD | PMID:20106945 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:732432 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NUPR1 mRNA | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NUPR1 mRNA | CTD | PMID:18796159 more ... | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:732432 | 6480464 | Tetrachlorodibenzodioxin affects the expression of NUPR1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:736958 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NUPR1 mRNA | CTD | PMID:20106945 PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of NUPR1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NUPR1 mRNA | CTD | PMID:18796159 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NUPR1 mRNA | CTD | PMID:18796159 PMID:19692669 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:732432 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NUPR1 mRNA | CTD | PMID:19933214 PMID:19770486 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NUPR1 mRNA | CTD | PMID:19692669 PMID:18796159 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:732432 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NUPR1 mRNA | CTD | PMID:19770486 PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NUPR1 mRNA | CTD | PMID:18796159 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:732432 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NUPR1 mRNA | CTD | PMID:19933214 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of NUPR1 mRNA | CTD | PMID:21346803 | 2-acetamidofluorene | decreases expression | EXP | | 6480464 | 2-Acetylaminofluorene results in decreased expression of NUPR1 mRNA | CTD | PMID:17070881 | 2-acetamidofluorene | decreases expression | EXP | | 6480464 | 2-Acetylaminofluorene results in decreased expression of NUPR1 mRNA | CTD | PMID:17070881 PMID:22584684 | 2-butoxyethanol | decreases expression | ISO | RGD:732432 | 6480464 | n-butoxyethanol results in decreased expression of NUPR1 mRNA | CTD | PMID:19812364 | 2-nitrofluorene | decreases expression | EXP | | 6480464 | 2-nitrofluorene results in decreased expression of NUPR1 mRNA | CTD | PMID:15890375 | 2-nitrofluorene | decreases expression | EXP | | 6480464 | 2-nitrofluorene results in decreased expression of NUPR1 mRNA | CTD | PMID:15890375 PMID:23052194 | 2-nitropropane | decreases expression | EXP | | 6480464 | 2-nitropropane results in decreased expression of NUPR1 mRNA | CTD | PMID:17070881 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NUPR1 mRNA | CTD | PMID:19692669 | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | decreases expression | EXP | | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of NUPR1 mRNA | CTD | PMID:15890375 | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | decreases expression | EXP | | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of NUPR1 mRNA | CTD | PMID:15890375 PMID:23052194 | 4-hydroxyphenyl retinamide | affects expression | ISO | RGD:736958 | 6480464 | Fenretinide affects the expression of NUPR1 mRNA | CTD | PMID:20022965 | 4-hydroxyphenyl retinamide | multiple interactions | ISO | RGD:736958 | 6480464 | NUPR1 mutant form promotes the reaction [Fenretinide affects the expression of ATF4 mRNA] | CTD | PMID:20022965 | 4-nitro-1,2-phenylenediamine | increases expression | EXP | | 6480464 | 1,2-diamino-4-nitrobenzene results in increased expression of NUPR1 mRNA | CTD | PMID:17070881 | 5-fluorouracil | affects expression | ISO | RGD:736958 | 6480464 | Fluorouracil affects the expression of NUPR1 mRNA | CTD | PMID:16584549 | aflatoxin B1 | decreases expression | ISO | RGD:732432 | 6480464 | Aflatoxin B1 results in decreased expression of NUPR1 mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of NUPR1 mRNA | CTD | PMID:15890375 PMID:23052194 | aflatoxin B1 | increases expression | ISO | RGD:736958 | 6480464 | Aflatoxin B1 results in increased expression of NUPR1 mRNA | CTD | PMID:21632981 PMID:21641981 | aflatoxin B1 | increases expression | ISO | RGD:736958 | 6480464 | Aflatoxin B1 results in increased expression of NUPR1 mRNA | CTD | PMID:21641981 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of NUPR1 mRNA | CTD | PMID:15890375 | all-trans-retinoic acid | increases expression | ISO | RGD:736958 | 6480464 | Tretinoin results in increased expression of NUPR1 mRNA | CTD | PMID:16249480 | amiodarone | increases expression | ISO | RGD:736958 | 6480464 | Amiodarone results in increased expression of NUPR1 mRNA | CTD | PMID:17567588 PMID:15342952 | amiodarone | increases expression | ISO | RGD:736958 | 6480464 | Amiodarone results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 more ... | amiodarone | increases expression | ISO | RGD:736958 | 6480464 | Amiodarone results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 PMID:17567588 | amitriptyline | increases expression | ISO | RGD:736958 | 6480464 | Amitriptyline results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 PMID:17567588 | amitriptyline | increases expression | ISO | RGD:736958 | 6480464 | Amitriptyline results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 more ... | amitriptyline | increases expression | ISO | RGD:736958 | 6480464 | Amitriptyline results in increased expression of NUPR1 mRNA | CTD | PMID:17567588 PMID:15342952 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of NUPR1 mRNA | CTD | PMID:16483693 | antimycin A | increases expression | ISO | RGD:732432 | 6480464 | Antimycin A results in increased expression of NUPR1 mRNA | CTD | PMID:19304788 | benzo[a]pyrene | decreases expression | ISO | RGD:732432 | 6480464 | Benzo(a)pyrene results in decreased expression of NUPR1 mRNA | CTD | PMID:21715664 PMID:19770486 | benzo[a]pyrene | decreases expression | ISO | RGD:732432 | 6480464 | Benzo(a)pyrene results in decreased expression of NUPR1 mRNA | CTD | PMID:15034205 more ... | benzo[a]pyrene | multiple interactions | ISO | RGD:732432 | 6480464 | AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of NUPR1 mRNA] | CTD | PMID:15034205 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of NUPR1 mRNA; more ... | CTD | PMID:18711122 | benzo[a]pyrene | increases expression | ISO | RGD:736958 | 6480464 | Benzo(a)pyrene results in increased expression of NUPR1 mRNA | CTD | PMID:20106945 PMID:21632981 | benzo[a]pyrene | increases expression | ISO | RGD:732432 | 6480464 | Benzo(a)pyrene results in increased expression of NUPR1 mRNA | CTD | PMID:20127859 more ... | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of NUPR1 mRNA | CTD | PMID:21839799 | benzo[a]pyrene | decreases expression | ISO | RGD:732432 | 6480464 | Benzo(a)pyrene results in decreased expression of NUPR1 mRNA | CTD | PMID:19770486 PMID:21715664 | benzo[a]pyrene | decreases expression | ISO | RGD:732432 | 6480464 | Benzo(a)pyrene results in decreased expression of NUPR1 mRNA | CTD | PMID:21715664 | benzo[a]pyrene | increases expression | ISO | RGD:732432 | 6480464 | Benzo(a)pyrene results in increased expression of NUPR1 mRNA | CTD | PMID:20127859 PMID:20713471 | benzo[a]pyrene | multiple interactions | ISO | RGD:732432 | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of NUPR1 mRNA | CTD | PMID:21715664 | benzo[a]pyrene | increases expression | ISO | RGD:736958 | 6480464 | Benzo(a)pyrene results in increased expression of NUPR1 mRNA | CTD | PMID:20106945 | benzo[a]pyrene | increases expression | ISO | RGD:732432 | 6480464 | Benzo(a)pyrene results in increased expression of NUPR1 mRNA | CTD | PMID:20713471 PMID:20127859 | benzo[b]fluoranthene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of NUPR1 mRNA | CTD | PMID:18711122 | bis(2-ethylhexyl) phthalate | decreases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in decreased expression of NUPR1 mRNA | CTD | PMID:22584684 | bromobenzene | decreases expression | EXP | | 6480464 | bromobenzene results in decreased expression of NUPR1 mRNA | CTD | PMID:15056800 | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of NUPR1 promoter | CTD | PMID:22457795 | caffeine | multiple interactions | ISO | RGD:732432 | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of NUPR1 mRNA; more ... | CTD | PMID:20230807 | chlorpromazine | increases expression | ISO | RGD:736958 | 6480464 | Chlorpromazine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 | chlorpromazine | increases expression | ISO | RGD:736958 | 6480464 | Chlorpromazine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 PMID:17175557 | choline | multiple interactions | ISO | RGD:732432 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of NUPR1 mRNA | CTD | PMID:20938992 | cis-ketoconazole | increases expression | ISO | RGD:736958 | 6480464 | Ketoconazole results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 PMID:17567588 | cis-ketoconazole | increases expression | ISO | RGD:736958 | 6480464 | Ketoconazole results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 more ... | cis-ketoconazole | increases expression | ISO | RGD:736958 | 6480464 | Ketoconazole results in increased expression of NUPR1 mRNA | CTD | PMID:17567588 PMID:15342952 | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of NUPR1 mRNA | CTD | PMID:22023808 | citalopram | increases expression | ISO | RGD:736958 | 6480464 | Citalopram results in increased expression of NUPR1 mRNA | CTD | PMID:17567588 | clofibrate | decreases expression | ISO | RGD:732432 | 6480464 | Clofibrate results in decreased expression of NUPR1 mRNA | CTD | PMID:17585979 | clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of NUPR1 mRNA | CTD | PMID:12851107 | clomipramine | increases expression | ISO | RGD:736958 | 6480464 | Clomipramine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 | clomipramine | increases expression | ISO | RGD:736958 | 6480464 | Clomipramine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 PMID:17175557 | clozapine | increases expression | ISO | RGD:736958 | 6480464 | Clozapine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 | clozapine | increases expression | ISO | RGD:736958 | 6480464 | Clozapine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 PMID:17175557 | cobalt atom | multiple interactions | ISO | RGD:736958 | 6480464 | [tungsten carbide co-treated with Cobalt] results in increased expression of NUPR1 mRNA | CTD | PMID:18078969 | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of NUPR1 mRNA | CTD | PMID:20187946 | copper atom | multiple interactions | ISO | RGD:736958 | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of NUPR1 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | RGD:736958 | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of NUPR1 mRNA | CTD | PMID:20971185 | coumarin | increases expression | EXP | | 6480464 | coumarin results in increased expression of NUPR1 mRNA | CTD | PMID:18480146 | cyclosporin A | increases expression | ISO | RGD:736958 | 6480464 | Cyclosporine results in increased expression of NUPR1 mRNA | CTD | PMID:20106945 | cyclosporin A | increases expression | ISO | RGD:736958 | 6480464 | Cyclosporine results in increased expression of NUPR1 mRNA | CTD | PMID:19159671 more ... | cyclosporin A | increases expression | ISO | RGD:736958 | 6480464 | Cyclosporine results in increased expression of NUPR1 mRNA | CTD | PMID:20106945 PMID:22147139 | cyclosporin A | increases expression | ISO | RGD:732432 | 6480464 | Cyclosporine results in increased expression of NUPR1 mRNA | CTD | PMID:19770486 | D-glucose | decreases abundance | ISO | RGD:736958 | 6480464 | NUPR1 results in decreased abundance of Glucose | CTD | PMID:16822955 | Delta(9)-tetrahydrocannabinol | increases expression | EXP | | 6480464 | Tetrahydrocannabinol results in increased expression of NUPR1 protein | CTD | PMID:16616335 | Delta(9)-tetrahydrocannabinol | increases expression | ISO | RGD:736958 | 6480464 | Tetrahydrocannabinol results in increased expression of NUPR1 mRNA | CTD | PMID:16616335 more ... | Delta(9)-tetrahydrocannabinol | multiple interactions | EXP | | 6480464 | thermozymocidin inhibits the reaction [Tetrahydrocannabinol results in increased expression of NUPR1 mRNA] | CTD | PMID:16616335 | Delta(9)-tetrahydrocannabinol | increases response to substance | ISO | RGD:732432 | 6480464 | NUPR1 results in increased susceptibility to Tetrahydrocannabinol | CTD | PMID:16616335 | Delta(9)-tetrahydrocannabinol | decreases expression | ISO | RGD:736958 | 6480464 | Tetrahydrocannabinol results in decreased expression of NUPR1 mRNA | CTD | PMID:18454173 | Delta(9)-tetrahydrocannabinol | increases expression | ISO | RGD:736958 | 6480464 | Tetrahydrocannabinol results in increased expression of NUPR1 protein | CTD | PMID:16616335 | Delta(9)-tetrahydrocannabinol | multiple interactions | ISO | RGD:732432 | 6480464 | NUPR1 affects the reaction [Tetrahydrocannabinol results in increased expression of TRIB3 mRNA]; more ... | CTD | PMID:16616335 | Delta(9)-tetrahydrocannabinol | increases expression | ISO | RGD:732432 | 6480464 | Tetrahydrocannabinol results in increased expression of NUPR1 mRNA | CTD | PMID:21542829 | Delta(9)-tetrahydrocannabinol | multiple interactions | EXP | | 6480464 | AREG inhibits the reaction [Tetrahydrocannabinol results in increased expression of NUPR1 mRNA] | CTD | PMID:19229996 | Delta(9)-tetrahydrocannabinol | multiple interactions | ISO | RGD:736958 | 6480464 | thermozymocidin inhibits the reaction [Tetrahydrocannabinol results in increased expression of NUPR1 mRNA]; more ... | CTD | PMID:16818650 | Delta(9)-tetrahydrocannabinol | increases expression | ISO | RGD:736958 | 6480464 | Tetrahydrocannabinol results in increased expression of NUPR1 mRNA | CTD | PMID:18454173 more ... | Delta(9)-tetrahydrocannabinol | multiple interactions | ISO | RGD:736958 | 6480464 | NUPR1 affects the reaction [Tetrahydrocannabinol results in increased expression of DDIT3 mRNA]; more ... | CTD | PMID:16616335 | Delta(9)-tetrahydrocannabinol | multiple interactions | ISO | RGD:736958 | 6480464 | ALK mutant form promotes the reaction [Tetrahydrocannabinol results in increased expression of NUPR1 mRNA]; more ... | CTD | PMID:21233844 | Delta(9)-tetrahydrocannabinol | increases response to substance | EXP | | 6480464 | NUPR1 results in increased susceptibility to Tetrahydrocannabinol | CTD | PMID:16616335 | Delta(9)-tetrahydrocannabinol | increases expression | EXP | | 6480464 | Tetrahydrocannabinol results in increased expression of NUPR1 mRNA | CTD | PMID:16616335 PMID:19229996 | diarsenic trioxide | increases expression | ISO | RGD:736958 | 6480464 | arsenic trioxide results in increased expression of NUPR1 mRNA | CTD | PMID:19128835 | dibenz[a,h]anthracene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of NUPR1 mRNA; more ... | CTD | PMID:18711122 | dibenzo[a,l]pyrene | multiple interactions | EXP | | 6480464 | [1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of NUPR1 mRNA | CTD | PMID:18711122 | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of NUPR1 mRNA | CTD | PMID:15890375 | doxepin | increases expression | ISO | RGD:736958 | 6480464 | Doxepin results in increased expression of NUPR1 mRNA | CTD | PMID:17567588 | erythromycin A | increases expression | ISO | RGD:736958 | 6480464 | Erythromycin results in increased expression of NUPR1 mRNA | CTD | PMID:17175557 | erythromycin A | decreases expression | ISO | RGD:736958 | 6480464 | Erythromycin results in decreased expression of NUPR1 mRNA | CTD | PMID:17175557 | etoposide | affects response to substance | ISO | RGD:736958 | 6480464 | NUPR1 protein affects the susceptibility to Etoposide | CTD | PMID:16217747 | fluoranthene | multiple interactions | EXP | | 6480464 | [1,2,5,6-dibenzanthracene co-treated with fluoranthene] affects the expression of NUPR1 mRNA | CTD | PMID:18711122 | fluoxetine | increases expression | ISO | RGD:736958 | 6480464 | Fluoxetine results in increased expression of NUPR1 mRNA | CTD | PMID:17567588 PMID:15342952 | fluoxetine | increases expression | ISO | RGD:736958 | 6480464 | Fluoxetine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 more ... | fluoxetine | increases expression | ISO | RGD:736958 | 6480464 | Fluoxetine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 PMID:17567588 | folic acid | multiple interactions | ISO | RGD:732432 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of NUPR1 mRNA | CTD | PMID:20938992 | fonofos | decreases methylation | ISO | RGD:736958 | 6480464 | Fonofos results in decreased methylation of NUPR1 promoter | CTD | PMID:22847954 | glucose | decreases abundance | ISO | RGD:736958 | 6480464 | NUPR1 results in decreased abundance of Glucose | CTD | PMID:16822955 | haloperidol | increases expression | ISO | RGD:736958 | 6480464 | Haloperidol results in increased expression of NUPR1 mRNA | CTD | PMID:17175557 | hydralazine | multiple interactions | ISO | RGD:736958 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of NUPR1 mRNA | CTD | PMID:17183730 | imipramine | increases expression | ISO | RGD:736958 | 6480464 | Imipramine results in increased expression of NUPR1 mRNA | CTD | PMID:17567588 PMID:15342952 | imipramine | increases expression | ISO | RGD:736958 | 6480464 | Imipramine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 PMID:17567588 | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of NUPR1 mRNA | CTD | PMID:21396975 | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NUPR1 mRNA | CTD | PMID:22129741 | isoniazide | increases expression | ISO | RGD:736958 | 6480464 | Isoniazid results in increased expression of NUPR1 mRNA | CTD | PMID:17175557 | L-methionine | multiple interactions | ISO | RGD:732432 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of NUPR1 mRNA | CTD | PMID:20938992 | lead diacetate | increases expression | EXP | | 6480464 | lead acetate results in increased expression of NUPR1 mRNA | CTD | PMID:22641619 | methapyrilene | increases expression | EXP | | 6480464 | Methapyrilene results in increased expression of NUPR1 mRNA | CTD | PMID:15890375 | microcystin-LR | increases expression | ISO | RGD:732432 | 6480464 | cyanoginosin LR results in increased expression of NUPR1 mRNA | CTD | PMID:17654400 | myriocin | multiple interactions | ISO | RGD:736958 | 6480464 | thermozymocidin inhibits the reaction [Tetrahydrocannabinol results in increased expression of NUPR1 mRNA] | CTD | PMID:16818650 | myriocin | multiple interactions | EXP | | 6480464 | thermozymocidin inhibits the reaction [Tetrahydrocannabinol results in increased expression of NUPR1 mRNA] | CTD | PMID:16616335 | N-acetyl-L-cysteine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NUPR1 mRNA | CTD | PMID:22129741 | N-methyl-4-phenylpyridinium | increases expression | ISO | RGD:732432 | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of NUPR1 mRNA | CTD | PMID:22776087 | N-nitrosodiethylamine | decreases expression | ISO | RGD:736958 | 6480464 | Diethylnitrosamine results in decreased expression of NUPR1 mRNA | CTD | PMID:21527772 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NUPR1 mRNA | CTD | PMID:22129741 | N-nitrosodimethylamine | decreases expression | EXP | | 6480464 | Dimethylnitrosamine results in decreased expression of NUPR1 mRNA | CTD | PMID:15890375 | nitric oxide | decreases expression | ISO | RGD:732432 | 6480464 | Nitric Oxide deficiency results in decreased expression of NUPR1 mRNA | CTD | PMID:15878706 | ofloxacin | increases expression | ISO | RGD:736958 | 6480464 | Ofloxacin results in increased expression of NUPR1 mRNA | CTD | PMID:17175557 | paclitaxel | increases expression | EXP | | 6480464 | Paclitaxel results in increased expression of NUPR1 mRNA | CTD | PMID:18754875 | paracetamol | affects expression | ISO | RGD:732432 | 6480464 | Acetaminophen affects the expression of NUPR1 mRNA | CTD | PMID:17562736 | parathion | decreases methylation | ISO | RGD:736958 | 6480464 | Parathion results in decreased methylation of NUPR1 promoter | CTD | PMID:22847954 | pentamidine | increases expression | ISO | RGD:736958 | 6480464 | Pentamidine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of NUPR1 mRNA | CTD | PMID:19162173 | perhexiline | increases expression | ISO | RGD:736958 | 6480464 | Perhexiline results in increased expression of NUPR1 mRNA | CTD | PMID:17175557 | phenobarbital | multiple interactions | ISO | RGD:732432 | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of NUPR1 mRNA] | CTD | PMID:19482888 | phenobarbital | affects expression | ISO | RGD:732432 | 6480464 | Phenobarbital affects the expression of NUPR1 mRNA | CTD | PMID:23091169 | phenobarbital | increases expression | ISO | RGD:736958 | 6480464 | Phenobarbital results in increased expression of NUPR1 mRNA | CTD | PMID:17175557 | phenobarbital | affects expression | ISO | RGD:736958 | 6480464 | Phenobarbital affects the expression of NUPR1 mRNA | CTD | PMID:19159669 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of NUPR1 mRNA | CTD | PMID:19162173 | phenobarbital | increases expression | ISO | RGD:732432 | 6480464 | Phenobarbital results in increased expression of NUPR1 mRNA | CTD | PMID:19482888 | piperonyl butoxide | increases expression | EXP | | 6480464 | Piperonyl Butoxide results in increased expression of NUPR1 mRNA | CTD | PMID:15890375 | pirinixic acid | multiple interactions | ISO | RGD:732432 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of NUPR1 mRNA | CTD | PMID:19710929 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of NUPR1 mRNA | CTD | PMID:15890375 PMID:19162173 | pirinixic acid | increases expression | ISO | RGD:732432 | 6480464 | pirinixic acid results in increased expression of NUPR1 mRNA | CTD | PMID:20813756 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of NUPR1 mRNA | CTD | PMID:19162173 PMID:15890375 | pirinixic acid | decreases expression | ISO | RGD:732432 | 6480464 | pirinixic acid results in decreased expression of NUPR1 mRNA | CTD | PMID:17426115 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of NUPR1 mRNA | CTD | PMID:19162173 | quercetin | increases expression | ISO | RGD:736958 | 6480464 | Quercetin results in increased expression of NUPR1 mRNA | CTD | PMID:21632981 | quinidine | increases expression | ISO | RGD:736958 | 6480464 | Quinidine results in increased expression of NUPR1 mRNA | CTD | PMID:17567588 | quinolin-8-ol | increases expression | ISO | RGD:736958 | 6480464 | Oxyquinoline results in increased expression of NUPR1 mRNA | CTD | PMID:21632981 | ranitidine | multiple interactions | EXP | | 6480464 | [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of NUPR1 mRNA | CTD | PMID:16415329 | rotenone | increases expression | ISO | RGD:732432 | 6480464 | Rotenone results in increased expression of NUPR1 mRNA | CTD | PMID:19304788 | S-butyl-DL-homocysteine (S,R)-sulfoximine | decreases expression | ISO | RGD:732432 | 6480464 | Buthionine Sulfoximine results in decreased expression of NUPR1 mRNA | CTD | PMID:15878706 | sertraline | increases expression | ISO | RGD:736958 | 6480464 | Sertraline results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 PMID:17567588 | sertraline | increases expression | ISO | RGD:736958 | 6480464 | Sertraline results in increased expression of NUPR1 mRNA | CTD | PMID:17567588 PMID:15342952 | silicon dioxide | increases expression | ISO | RGD:732432 | 6480464 | Silicon Dioxide results in increased expression of NUPR1 mRNA | CTD | PMID:19073995 | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of NUPR1 mRNA | CTD | PMID:22110744 | sodium dichromate | increases expression | ISO | RGD:732432 | 6480464 | sodium bichromate results in increased expression of NUPR1 mRNA | CTD | PMID:22155349 | sotalol | increases expression | ISO | RGD:736958 | 6480464 | Sotalol results in increased expression of NUPR1 mRNA | CTD | PMID:17175557 | succimer | multiple interactions | ISO | RGD:732432 | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of NUPR1 mRNA | CTD | PMID:21641980 | tamoxifen | increases expression | ISO | RGD:736958 | 6480464 | Tamoxifen results in increased expression of NUPR1 mRNA | CTD | PMID:17567588 | tamoxifen | increases expression | ISO | RGD:736958 | 6480464 | Tamoxifen results in increased expression of NUPR1 mRNA | CTD | PMID:17175557 PMID:17567588 | terbufos | decreases methylation | ISO | RGD:736958 | 6480464 | terbufos results in decreased methylation of NUPR1 promoter | CTD | PMID:22847954 | tetrachloromethane | increases response to substance | ISO | RGD:732432 | 6480464 | NUPR1 gene mutant form results in increased susceptibility to Carbon Tetrachloride | CTD | PMID:15962327 | tetrachloromethane | affects expression | ISO | RGD:732432 | 6480464 | Carbon Tetrachloride affects the expression of NUPR1 mRNA | CTD | PMID:17484886 | tetrachloromethane | multiple interactions | ISO | RGD:732432 | 6480464 | NUPR1 protein affects the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA]; more ... | CTD | PMID:15962327 | tetrachloromethane | increases expression | ISO | RGD:732432 | 6480464 | Carbon Tetrachloride results in increased expression of NUPR1 protein | CTD | PMID:15962327 | tetracycline | increases expression | ISO | RGD:736958 | 6480464 | Tetracycline results in increased expression of NUPR1 mRNA | CTD | PMID:17175557 | thapsigargin | multiple interactions | ISO | RGD:736958 | 6480464 | NUPR1 mutant form promotes the reaction [Thapsigargin results in increased expression of ATF4 mRNA] | CTD | PMID:20022965 | thapsigargin | increases expression | ISO | RGD:736958 | 6480464 | Thapsigargin results in increased expression of NUPR1 mRNA | CTD | PMID:20022965 | thioridazine | increases expression | ISO | RGD:736958 | 6480464 | Thioridazine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 | thioridazine | increases expression | ISO | RGD:736958 | 6480464 | Thioridazine results in increased expression of NUPR1 mRNA | CTD | PMID:15342952 PMID:17175557 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of NUPR1 mRNA | CTD | PMID:17905399 | ursodeoxycholic acid | increases expression | EXP | | 6480464 | Ursodeoxycholic Acid results in increased expression of NUPR1 mRNA | CTD | PMID:15885361 | valproic acid | multiple interactions | ISO | RGD:736958 | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of NUPR1 mRNA | CTD | PMID:17183730 | valproic acid | decreases expression | ISO | RGD:736958 | 6480464 | Valproic Acid results in decreased expression of NUPR1 mRNA | CTD | PMID:17175557 | vancomycin | decreases expression | ISO | RGD:732432 | 6480464 | Vancomycin results in decreased expression of NUPR1 mRNA | CTD | PMID:18930951 | |
Gene Ontology AnnotationsBiological Process







