Nppa (natriuretic peptide A) - Rat Genome Database

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Keyword

Gene: Nppa (natriuretic peptide A) Rattus norvegicus

Symbol:

Nppa

Name:

natriuretic peptide A

Description:

ENCODES a protein that exhibits hormone activity; peptide hormone receptor binding; receptor binding; INVOLVED IN cGMP biosynthetic process; negative regulation of cell growth; receptor guanylyl cyclase signaling pathway; PARTICIPATES IN atrial natriuretic peptide signaling pathway; ASSOCIATED WITH increased heart weight; increased left ventricle weight; increased systemic arterial systolic blood pressure; ASSOCIATED WITH Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hypertension; FOUND IN cytoplasm; mast cell granule; nucleus; INTERACTS WITH (R)-mevalonic acid; (R)-noradrenaline; 11-deoxycorticosterone

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

ANF; ANP; atrial natriuretic factor; atrial natriuretic peptide; Natriuretic peptide precursor A (pronatriodilatin also Anf Pnd); Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd); Natriuretic peptide precursor A, (pronatriodilatin, also Anf, Pnd); natriuretic peptide precursor type A; natriuretic peptides A; Pnd; prepronatriodilatin; RATANF

Orthologs:

Homo sapiens : NPPA (natriuretic peptide A) HGNC
Mus musculus : Nppa (natriuretic peptide type A) MGI

Allele / Splice:

Nppa^em4Mcwi

Is Marker For:

QTLs: Bp49 Strs2 Bp100

Latest Assembly:

RGSC Genome Assembly v3.4

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	5	q36		NCBI
RGSC Genome Assembly v5.0	5	168,466,309 - 168,467,618	+	NCBI
RGSC Genome Assembly v3.4	5	165,074,518 - 165,075,827	+	NCBI
Rat Celera Assembly	5	156,710,885 - 156,712,194	+	NCBI
Genome Assembly 3.1	5	165,084,713 - 165,086,000	+	NCBI
RH 3.4	5	1106.6		RGD