Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of OGFRL1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of OGFRL1 mRNA | CTD | PMID:21185374 | 17beta-estradiol | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of OGFRL1 mRNA and [Estradiol co-treated with TGFB1 protein] results in decreased expression of OGFRL1 mRNA | CTD | PMID:20823114 and PMID:30165855 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19095052 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of OGFRL1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of OGFRL1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of OGFRL1 mRNA | CTD | PMID:26290441 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ogfrl1 (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of OGFRL1 mRNA | CTD | PMID:25975270 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of OGFRL1 mRNA | CTD | PMID:22574217 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 5-azacytidine | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Azacitidine results in increased expression of OGFRL1 mRNA | CTD | PMID:20823114 | 5-fluorouracil | affects response to substance | ISO | OGFRL1 (Homo sapiens) | 6480464 | OGFRL1 protein affects the susceptibility to Fluorouracil | CTD | PMID:16217747 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of OGFRL1 mRNA | CTD | PMID:31881176 | acrolein | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of OGFRL1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of OGFRL1 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of OGFRL1 mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases methylation | ISO | OGFRL1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of OGFRL1 gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of OGFRL1 mRNA | CTD | PMID:21934132 and PMID:33167477 | all-trans-retinoic acid | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of OGFRL1 mRNA | CTD | PMID:23724009 | alpha-pinene | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of OGFRL1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of OGFRL1 mRNA | CTD | PMID:32699268 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of OGFRL1 mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of OGFRL1 mRNA | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of OGFRL1 mRNA | CTD | PMID:23650126 | bisphenol A | increases methylation | ISO | OGFRL1 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of OGFRL1 gene | CTD | PMID:22576693 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of OGFRL1 mRNA | CTD | PMID:30816183 and PMID:32528016 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of OGFRL1 mRNA | CTD | PMID:25181051 more ... | bisphenol A | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of OGFRL1 mRNA | CTD | PMID:22576693 and PMID:29275510 | bucladesine | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of OGFRL1 mRNA | CTD | PMID:20823114 | butanal | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of OGFRL1 mRNA | CTD | PMID:26079696 | carbon nanotube | increases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of OGFRL1 mRNA | CTD | PMID:25554681 | carbon nanotube | decreases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of OGFRL1 mRNA | CTD | PMID:25620056 | CGP 52608 | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to OGFRL1 gene] | CTD | PMID:28238834 | cisplatin | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of OGFRL1 mRNA | CTD | PMID:27594783 | cisplatin | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of OGFRL1 mRNA | CTD | PMID:27392435 | cisplatin | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of OGFRL1 mRNA | CTD | PMID:27392435 | cobalt dichloride | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of OGFRL1 mRNA | CTD | PMID:19320972 | copper atom | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of OGFRL1 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of OGFRL1 mRNA | CTD | PMID:20971185 | copper(II) sulfate | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of OGFRL1 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of OGFRL1 mRNA | CTD | PMID:25562108 | dexamethasone | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Dexamethasone results in increased expression of OGFRL1 mRNA | CTD | PMID:25047013 | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of OGFRL1 mRNA | CTD | PMID:25152437 | dorsomorphin | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OGFRL1 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of OGFRL1 mRNA | CTD | PMID:29803840 | epoxiconazole | increases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of OGFRL1 mRNA | CTD | PMID:35436446 | ethyl methanesulfonate | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of OGFRL1 mRNA | CTD | PMID:23649840 | fentin chloride | increases expression | EXP | | 6480464 | triphenyltin chloride results in increased expression of OGFRL1 mRNA | CTD | PMID:37156404 | fluoranthene | multiple interactions | ISO | Ogfrl1 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of OGFRL1 mRNA | CTD | PMID:28329830 | formaldehyde | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of OGFRL1 mRNA | CTD | PMID:23649840 | ivermectin | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of OGFRL1 protein | CTD | PMID:32959892 | lead(0) | affects expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Lead affects the expression of OGFRL1 mRNA | CTD | PMID:28903495 | lipopolysaccharide | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of OGFRL1 mRNA | CTD | PMID:35811015 | lipopolysaccharide | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of OGFRL1 mRNA | CTD | PMID:35811015 | medroxyprogesterone acetate | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of OGFRL1 mRNA | CTD | PMID:20823114 | methyl methanesulfonate | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of OGFRL1 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of OGFRL1 mRNA | CTD | PMID:23179753 and PMID:28001369 | methylmercury chloride | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of OGFRL1 mRNA | CTD | PMID:28001369 | N-methyl-4-phenylpyridinium | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of OGFRL1 mRNA | CTD | PMID:24810058 | N-methyl-N-nitrosourea | increases expression | EXP | | 6480464 | Methylnitrosourea results in increased expression of OGFRL1 mRNA | CTD | PMID:17412507 | nickel dichloride | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | nickel chloride results in increased expression of OGFRL1 mRNA | CTD | PMID:17312168 | ochratoxin A | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | ochratoxin A results in decreased expression of OGFRL1 mRNA | CTD | PMID:30559759 | ozone | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of OGFRL1 mRNA more ... | CTD | PMID:32699268 | ozone | multiple interactions | ISO | Ogfrl1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of OGFRL1 mRNA | CTD | PMID:27106289 | paracetamol | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of OGFRL1 mRNA | CTD | PMID:29067470 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of OGFRL1 mRNA | CTD | PMID:33387578 | phenobarbital | multiple interactions | ISO | Ogfrl1 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of OGFRL1 mRNA] | CTD | PMID:19482888 | phenobarbital | affects expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | Phenobarbital affects the expression of OGFRL1 mRNA | CTD | PMID:23091169 | phenobarbital | affects expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of OGFRL1 mRNA | CTD | PMID:19159669 | phenobarbital | decreases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of OGFRL1 mRNA | CTD | PMID:19482888 | phenylmercury acetate | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of OGFRL1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OGFRL1 mRNA | CTD | PMID:27188386 | pirinixic acid | decreases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of OGFRL1 mRNA | CTD | PMID:23811191 | potassium chromate | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of OGFRL1 mRNA | CTD | PMID:22714537 | quercetin | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of OGFRL1 mRNA | CTD | PMID:21632981 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of OGFRL1 mRNA | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | OGFRL1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OGFRL1 mRNA | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of OGFRL1 mRNA | CTD | PMID:25895662 | silicon dioxide | decreases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of OGFRL1 mRNA | CTD | PMID:19073995 | sodium arsenite | decreases methylation | ISO | Ogfrl1 (Mus musculus) | 6480464 | sodium arsenite results in decreased methylation of OGFRL1 gene | CTD | PMID:32068019 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of OGFRL1 mRNA | CTD | PMID:19281266 | succimer | multiple interactions | ISO | Ogfrl1 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of OGFRL1 mRNA | CTD | PMID:21641980 | sunitinib | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of OGFRL1 mRNA | CTD | PMID:31533062 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of OGFRL1 mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of OGFRL1 mRNA | CTD | PMID:34492290 | torcetrapib | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of OGFRL1 mRNA | CTD | PMID:23228038 | trichostatin A | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of OGFRL1 mRNA | CTD | PMID:24935251 | trichostatin A | decreases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of OGFRL1 mRNA | CTD | PMID:24935251 | triclosan | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Triclosan results in increased expression of OGFRL1 mRNA | CTD | PMID:30510588 | trovafloxacin | decreases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of OGFRL1 mRNA | CTD | PMID:35537566 | tungsten | decreases expression | ISO | Ogfrl1 (Mus musculus) | 6480464 | Tungsten results in decreased expression of OGFRL1 mRNA | CTD | PMID:30912803 | urethane | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Urethane results in increased expression of OGFRL1 mRNA | CTD | PMID:28818685 | valproic acid | decreases methylation | ISO | OGFRL1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of OGFRL1 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | OGFRL1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of OGFRL1 mRNA | CTD | PMID:23179753 more ... | |