| (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:69480 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of PDK1 mRNA | CTD | PMID:22079256 |
| 1,10-phenanthroline | increases expression | ISO | RGD:69480 | 6480464 | 1,10-phenanthroline results in increased expression of PDK1 mRNA | CTD | PMID:19502547 |
| 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:1552738 | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PDK1 mRNA] | CTD | PMID:21851831 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1552738 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PDK1 mRNA | CTD | PMID:19933214 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1552738 | 6480464 | Tetrachlorodibenzodioxin affects the expression of PDK1 mRNA | CTD | PMID:21570461 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PDK1 mRNA | CTD | PMID:22298810 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1552738 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PDK1 mRNA | CTD | PMID:19770486 PMID:21851831 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1552738 | 6480464 | 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PDK1 mRNA] | CTD | PMID:21851831 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1552738 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PDK1 mRNA | CTD | PMID:19770486 |
| 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of PDK1 mRNA | CTD | PMID:21346803 |
| 2-butoxyethanol | increases expression | ISO | RGD:1552738 | 6480464 | n-butoxyethanol results in increased expression of PDK1 mRNA | CTD | PMID:19812364 |
| aflatoxin B1 | decreases expression | ISO | RGD:1552738 | 6480464 | Aflatoxin B1 results in decreased expression of PDK1 mRNA | CTD | PMID:19770486 |
| aflatoxin B1 | decreases expression | ISO | RGD:69480 | 6480464 | Aflatoxin B1 results in decreased expression of PDK1 mRNA | CTD | PMID:21641981 |
| all-trans-retinoic acid | decreases expression | ISO | RGD:1552738 | 6480464 | Tretinoin results in decreased expression of PDK1 mRNA | CTD | PMID:16604517 |
| all-trans-retinoic acid | increases expression | ISO | RGD:69480 | 6480464 | Tretinoin results in increased expression of PDK1 mRNA | CTD | PMID:21934132 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PDK1 mRNA | CTD | PMID:16483693 |
| benzo[a]pyrene | decreases expression | ISO | RGD:69480 | 6480464 | Benzo(a)pyrene results in decreased expression of PDK1 mRNA | CTD | PMID:20106945 |
| benzo[a]pyrene | decreases expression | ISO | RGD:1552738 | 6480464 | Benzo(a)pyrene results in decreased expression of PDK1 mRNA | CTD | PMID:22610609 |
| benzo[a]pyrene | decreases expression | ISO | RGD:69480 | 6480464 | Benzo(a)pyrene results in decreased expression of PDK1 mRNA | CTD | PMID:20106945 PMID:21632981 |
| bilirubin | decreases expression | ISO | RGD:69480 | 6480464 | Bilirubin results in decreased expression of PDK1 mRNA | CTD | PMID:20196124 |
| bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PDK1 mRNA | CTD | PMID:12075121 |
| cobalt atom | multiple interactions | ISO | RGD:69480 | 6480464 | [tungsten carbide binds to Cobalt] which results in increased expression of PDK1 mRNA | CTD | PMID:20105288 |
| cobalt dichloride | increases expression | ISO | RGD:69480 | 6480464 | cobaltous chloride results in increased expression of PDK1 mRNA | CTD | PMID:20105288 |
| cobalt dichloride | increases expression | ISO | RGD:69480 | 6480464 | cobaltous chloride results in increased expression of PDK1 mRNA | CTD | PMID:19502547 more ... |
| cobalt dichloride | increases expression | ISO | RGD:69480 | 6480464 | cobaltous chloride results in increased expression of PDK1 mRNA | CTD | PMID:20105288 more ... |
| cobalt dichloride | multiple interactions | ISO | RGD:69480 | 6480464 | zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PDK1 mRNA] | CTD | PMID:22202117 |
| cobalt dichloride | increases expression | ISO | RGD:69480 | 6480464 | cobaltous chloride results in increased expression of PDK1 mRNA | CTD | PMID:19502547 PMID:20105288 |
| cobalt(2+) sulfate | increases expression | ISO | RGD:69480 | 6480464 | cobalt sulfate results in increased expression of PDK1 mRNA | CTD | PMID:19502547 |
| copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of PDK1 mRNA | CTD | PMID:22465980 |
| copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of PDK1 mRNA | CTD | PMID:22465980 |
| corticosterone | multiple interactions | ISO | RGD:1552738 | 6480464 | Corticosterone results in increased phosphorylation of and results in increased activity of PDK1 protein; more ... | CTD | PMID:21655274 |
| curcumin | multiple interactions | ISO | RGD:69480 | 6480464 | Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein]; more ... | CTD | PMID:17171638 |
| curcumin | increases phosphorylation | ISO | RGD:69480 | 6480464 | Curcumin results in increased phosphorylation of PDK1 protein | CTD | PMID:17171638 |
| cyclosporin A | decreases expression | ISO | RGD:69480 | 6480464 | Cyclosporine results in decreased expression of PDK1 mRNA | CTD | PMID:21632981 |
| D-glucose | multiple interactions | EXP | | 6480464 | PDK1 protein promotes the reaction [NRG1 protein results in increased transport of Glucose] | CTD | PMID:14711829 |
| dexamethasone | increases phosphorylation | ISO | RGD:1552738 | 6480464 | Dexamethasone results in increased phosphorylation of PDK1 protein | CTD | PMID:21655274 |
| dexamethasone | multiple interactions | ISO | RGD:1552738 | 6480464 | wortmannin inhibits the reaction [Dexamethasone results in increased phosphorylation of PDK1 protein] | CTD | PMID:21655274 |
| diazoxide | increases expression | ISO | RGD:1552738 | 6480464 | Isoproterenol results in increased expression of PDK1 mRNA | CTD | PMID:20003209 |
| dibutyl phthalate | decreases expression | ISO | RGD:1552738 | 6480464 | Dibutyl Phthalate results in decreased expression of PDK1 mRNA | CTD | PMID:21266533 |
| dioxygen | multiple interactions | ISO | RGD:69480 | 6480464 | [Rotenone co-treated with Thenoyltrifluoroacetone] inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA] | CTD | PMID:17671207 |
| dioxygen | increases expression | ISO | RGD:1552738 | 6480464 | Oxygen deficiency results in increased expression of PDK1 mRNA | CTD | PMID:20880076 |
| dioxygen | increases expression | ISO | RGD:69480 | 6480464 | Oxygen deficiency results in increased expression of PDK1 mRNA | CTD | PMID:17175027 more ... |
| dioxygen | increases expression | ISO | RGD:69480 | 6480464 | Oxygen deficiency results in increased expression of PDK1 mRNA | CTD | PMID:19502547 more ... |
| dioxygen | increases expression | ISO | RGD:69480 | 6480464 | Oxygen deficiency results in increased expression of PDK1 mRNA | CTD | PMID:19502547 more ... |
| dioxygen | increases expression | ISO | RGD:69480 | 6480464 | Oxygen deficiency results in increased expression of PDK1 mRNA | CTD | PMID:17175027 more ... |
| dioxygen | increases expression | ISO | RGD:69480 | 6480464 | Oxygen deficiency results in increased expression of PDK1 mRNA | CTD | PMID:17671207 more ... |
| dioxygen | increases expression | ISO | RGD:69480 | 6480464 | Oxygen deficiency results in increased expression of PDK1 mRNA | CTD | PMID:17671207 PMID:17175027 |
| genistein | decreases phosphorylation | ISO | RGD:69480 | 6480464 | Genistein results in decreased phosphorylation of PDK1 protein | CTD | PMID:18431742 |
| glucose | multiple interactions | EXP | | 6480464 | PDK1 protein promotes the reaction [NRG1 protein results in increased transport of Glucose] | CTD | PMID:14711829 |
| glutathione | multiple interactions | ISO | RGD:69480 | 6480464 | Glutathione inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein] | CTD | PMID:17171638 |
| heptadecafluorononanoic acid | decreases expression | EXP | | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of PDK1 protein modified form | CTD | PMID:22387981 |
| isoprenaline | increases expression | ISO | RGD:1552738 | 6480464 | Isoproterenol results in increased expression of PDK1 mRNA | CTD | PMID:20003209 |
| lead(0) | decreases expression | ISO | RGD:69480 | 6480464 | Lead results in decreased expression of PDK1 mRNA | CTD | PMID:19921347 |
| LY294002 | multiple interactions | ISO | RGD:69480 | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the localization of [PDK1 protein binds to AKT1 protein]; more ... | CTD | PMID:20361045 |
| manganese atom | increases expression | ISO | RGD:69480 | 6480464 | Manganese results in increased expression of PDK1 mRNA | CTD | PMID:17175027 |
| manganese(0) | increases expression | ISO | RGD:69480 | 6480464 | Manganese results in increased expression of PDK1 mRNA | CTD | PMID:17175027 |
| manganese(II) chloride | increases expression | ISO | RGD:69480 | 6480464 | manganese chloride results in increased expression of PDK1 mRNA | CTD | PMID:17175027 |
| methotrexate | affects response to substance | ISO | RGD:69480 | 6480464 | PDK1 protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 |
| morphine | decreases expression | EXP | | 6480464 | Morphine results in decreased expression of PDK1 protein | CTD | PMID:23056601 |
| N-acetyl-L-cysteine | multiple interactions | ISO | RGD:69480 | 6480464 | Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein] | CTD | PMID:17171638 |
| N-methyl-N-nitrosurea | increases expression | EXP | | 6480464 | Methylnitrosourea results in increased expression of PDK1 mRNA | CTD | PMID:16525678 |
| N-nitrosodiethylamine | multiple interactions | ISO | RGD:1552738 | 6480464 | CTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of PDK1 protein] | CTD | PMID:20583210 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | morin inhibits the reaction [Diethylnitrosamine results in increased expression of PDK1 protein modified form] | CTD | PMID:19931519 |
| N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of PDK1 protein modified form | CTD | PMID:19931519 |
| N-nitrosodiethylamine | increases phosphorylation | ISO | RGD:1552738 | 6480464 | Diethylnitrosamine results in increased phosphorylation of PDK1 protein | CTD | PMID:20583210 |
| nickel dichloride | increases expression | EXP | | 6480464 | nickel chloride results in increased expression of PDK1 mRNA | CTD | PMID:22110744 |
| nickel dichloride | increases expression | ISO | RGD:69480 | 6480464 | nickel chloride results in increased expression of PDK1 mRNA | CTD | PMID:21455298 |
| ochratoxin A | increases phosphorylation | EXP | | 6480464 | ochratoxin A results in increased phosphorylation of PDK1 protein | CTD | PMID:17651772 |
| ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of PDK1 protein | CTD | PMID:17651772 |
| paclitaxel | multiple interactions | ISO | RGD:69480 | 6480464 | [PDK1 protein binds to AKT1 protein] which results in decreased susceptibility to Paclitaxel; more ... | CTD | PMID:20361045 |
| paracetamol | affects expression | ISO | RGD:1552738 | 6480464 | Acetaminophen affects the expression of PDK1 mRNA | CTD | PMID:17562736 |
| phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of PDK1 mRNA | CTD | PMID:19162173 |
| pirinixic acid | multiple interactions | ISO | RGD:1552738 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PDK1 mRNA | CTD | PMID:19710929 |
| pirinixic acid | increases expression | ISO | RGD:1552738 | 6480464 | pirinixic acid results in increased expression of PDK1 mRNA | CTD | PMID:17426115 |
| propiconazole | decreases expression | ISO | RGD:1552738 | 6480464 | propiconazole results in decreased expression of PDK1 mRNA | CTD | PMID:21278054 |
| quercetin | decreases expression | ISO | RGD:69480 | 6480464 | Quercetin results in decreased expression of PDK1 mRNA | CTD | PMID:21632981 |
| quinolin-8-ol | decreases expression | ISO | RGD:69480 | 6480464 | Oxyquinoline results in decreased expression of PDK1 mRNA | CTD | PMID:21632981 |
| rosiglitazone | affects expression | ISO | RGD:1552738 | 6480464 | rosiglitazone affects the expression of PDK1 mRNA | CTD | PMID:22013433 |
| rotenone | multiple interactions | ISO | RGD:69480 | 6480464 | [Rotenone co-treated with Thenoyltrifluoroacetone] inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA] | CTD | PMID:17671207 |
| S-butyl-DL-homocysteine (S,R)-sulfoximine | multiple interactions | ISO | RGD:69480 | 6480464 | Buthionine Sulfoximine promotes the reaction [Curcumin results in increased phosphorylation of PDK1 protein] | CTD | PMID:17171638 |
| undecane | decreases expression | EXP | | 6480464 | undecane results in decreased expression of PDK1 protein | CTD | PMID:17337753 |
| wortmannin | multiple interactions | ISO | RGD:1552738 | 6480464 | wortmannin inhibits the reaction [Dexamethasone results in increased phosphorylation of PDK1 protein] | CTD | PMID:21655274 |
| zinc atom | increases expression | ISO | RGD:69480 | 6480464 | Zinc deficiency results in increased expression of PDK1 mRNA | CTD | PMID:18356318 |
| zinc dichloride | multiple interactions | ISO | RGD:69480 | 6480464 | zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of PDK1 mRNA] | CTD | PMID:22202117 |
| zinc(0) | increases expression | ISO | RGD:69480 | 6480464 | Zinc deficiency results in increased expression of PDK1 mRNA | CTD | PMID:18356318 |