Mlh1 (mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli))

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Keyword

Gene: Mlh1 (mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)) Rattus norvegicus

Symbol:

Mlh1

Name:

mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)

Description:

ENCODES a protein that exhibits guanine/thymine mispair binding (ortholog); MutSalpha complex binding (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN cellular response to organic cyclic compound; response to drug; response to hypoxia; PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; endometrial cancer pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Carcinoma, Renal Cell (ortholog); Cervical Intraepithelial Neoplasia (ortholog); FOUND IN nucleus; synaptonemal complex; chiasma (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; cyclophosphamide

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

DNA mismatch repair protein Mlh1; mismatch repair protein; mismatch repair protein 1; mutL homolog 1; mutL homolog 1 (E. coli); mutL protein homolog 1

Orthologs:

Homo sapiens : MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)) HGNC
Mus musculus : Mlh1 (mutL homolog 1 (E. coli)) MGI

Latest Assembly:

RGSC Genome Assembly v3.4

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	8	q32		NCBI
RGSC Genome Assembly v5.0	8	118,828,405 - 118,865,320	-	NCBI
RGSC Genome Assembly v3.4	8	115,616,396 - 115,653,471	-	NCBI
Rat Celera Assembly	8	110,478,307 - 110,515,168	-	NCBI
Genome Assembly 3.1	8	115,635,850 - 115,672,920	-	NCBI