Gene: Nos3 (nitric oxide synthase 3) Rattus norvegicus
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Symbol: Nos3
Name: nitric oxide synthase 3
Description: ENCODES a protein that exhibits actin binding; beta-catenin binding; cadherin binding; INVOLVED IN aging; bone development; cellular response to cAMP; PARTICIPATES IN doxorubicin pharmacokinetics pathway; eicosanoid signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH Arteriovenous Fistula; autosomal dominant polycystic kidney disease; benign hypertensive renal disease; FOUND IN apical part of cell; cytoplasm; cytosol; INTERACTS WITH (R)-carnitine; 1,3-dinitrobenzene; 11-deoxycorticosterone
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cNOS; constitutive NOS; EC-NOS; endothelial nitric oxide synthase 3; endothelial NOS; eNos; nitric oxide synthase 3, endothelial cell; nitric oxide synthase, endothelial; NOS type III; NOSIII
Orthologs:
Homo sapiens (human) : NOS3 (nitric oxide synthase 3)  HGNC  AGR
Mus musculus (house mouse) : Nos3 (nitric oxide synthase 3, endothelial cell)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Nos3 (nitric oxide synthase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NOS3 (nitric oxide synthase 3)
Canis lupus familiaris (dog) : NOS3 (nitric oxide synthase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nos3 (nitric oxide synthase 3)
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Allele / Splice: Nos3em2Mcwi   Nos3em8Mcwi   Nos3em13Mcwi  
Genetic Models: SS-Nos3em8Mcwi SS-Nos3em2Mcwi SS-Nos3em13Mcwi
Is Marker For: Strains:   WKY   DA.WF-(D4Mit11-Nos3)/Kop  
QTLs:   Tcas3   BW384_H  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.047,321,908 - 7,342,404 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.047,333,272 - 7,353,767 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.446,158,847 - 6,179,441 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.146,158,846 - 6,179,441 (-)NCBI
Celera46,408,408 - 6,428,650 (-)NCBI
Cytogenetic Map4q11NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences