Gene: Chat (choline O-acetyltransferase) Rattus norvegicus
Symbol: Chat
Name: choline O-acetyltransferase
Description: ENCODES a protein that exhibits choline binding; choline O-acetyltransferase activity; INVOLVED IN acetylcholine biosynthetic process; antral ovarian follicle growth; memory; PARTICIPATES IN acetylcholine metabolic pathway; acetylcholine signaling pathway via muscarinic acetylcholine receptor; acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH Alzheimer Disease; Asthma; Congenital Myasthenic Syndrome with Episodic Apnea (ortholog); FOUND IN neuron projection; axon (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (R)-lipoic acid
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CHOACTase; choline acetylase; choline acetyltransferase; LOC290567
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: partial on reference assembly
RGSC Genome Assembly v6.0168,630,194 - 8,686,131-NCBI
RGSC Genome Assembly v6.0168,576,858 - 8,583,314-NCBI
Rat Cytogenetic Map16p16 NCBI
RGSC Genome Assembly v5.0168,493,024 - 8,526,303-NCBI
RGSC Genome Assembly v5.01610,603,449 - 10,652,313-NCBI
RGSC Genome Assembly v3.4167,913,026 - 7,965,985-NCBI
Rat Celera Assembly167,483,676 - 7,543,221+NCBI
Genome Assembly 3.1167,913,023 - 7,968,456-NCBI
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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Chat
Entrez Gene
Ensembl Gene
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RGD Object Information
RGD ID: 1304627
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2015-11-09
Status: ACTIVE