Gene: Nppb (natriuretic peptide B) Rattus norvegicus
Symbol: Nppb
Name: natriuretic peptide B
Description: ENCODES a protein that exhibits hormone activity; peptide hormone receptor binding; receptor binding (ortholog); INVOLVED IN cell growth involved in cardiac muscle cell development; cellular response to mechanical stimulus; cGMP biosynthetic process; PARTICIPATES IN brain natriuretic peptide signaling pathway; ASSOCIATED WITH Acute Kidney Injury; Cardiomegaly; Diabetes Mellitus, Experimental; FOUND IN cytoplasm; extracellular space; nucleus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
Also known as: Bnf; BNP; Brain natriuretic factor; brain natriuretic peptide; gamma-brain natriuretic peptide; iso-ANP; natriuretic peptide precursor B; natriuretic peptide precursor type B; natriuretic peptides B
Allele / Splice: Nppbem2Mcwi   Nppbem4Mcwi  
Is Marker For: Strains:   SD  
QTLs:   Bp100  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05164,796,176 - 164,797,538 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.05168,454,278 - 168,455,640 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.45165,062,348 - 165,063,650 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15165,072,535 - 165,073,838 (+)NCBI
Celera5156,698,873 - 156,700,175 (+)NCBI
Cytogenetic Map5q36NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Nppb
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 3194
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-09-13
Status: ACTIVE