Gene: Cybb (cytochrome b-245 beta chain) Rattus norvegicus
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Symbol: Cybb
Name: cytochrome b-245 beta chain
Description: ENCODES a protein that exhibits electron transfer activity (ortholog); flavin adenine dinucleotide binding (ortholog); heme binding (ortholog); INVOLVED IN cellular response to cadmium ion; cellular response to ethanol; cellular response to hypoxia; PARTICIPATES IN thyroid hormone biosynthetic pathway; phagocytosis pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental; end stage renal failure; Hyperaldosteronism; FOUND IN dendrite; endoplasmic reticulum; Golgi apparatus; INTERACTS WITH (-)-epigallocatechin 3-gallate; (R)-carnitine; (R)-lipoic acid
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cytochrome b-245, beta polypeptide; endothelial type gp91-phox; endothelial type gp91-phox gene; Gp91-phox; NADPH oxidase 2; Nox2
Orthologs:
Homo sapiens (human) : CYBB (cytochrome b-245 beta chain)  HGNC  AGR
Mus musculus (house mouse) : Cybb (cytochrome b-245, beta polypeptide)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : LOC102012042 (cytochrome b-245 heavy chain)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100982531 (cytochrome b-245 heavy chain)
Canis lupus familiaris (dog) : CYBB (cytochrome b-245, beta polypeptide (chronic granulomatous disease))
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101966992 (cytochrome b-245 heavy chain)
more info ...
Allele / Splice: Cybbem1Mcwi   Cybbem3Mcwi  
Genetic Models: SS-Cybbem3Mcwi SS-Cybbem1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X14,578,330 - 14,610,049 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0X15,359,405 - 15,391,317 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4X25,514,572 - 25,547,181 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X25,568,040 - 25,600,650 (-)NCBI
CeleraX14,033,486 - 14,065,403 (+)NCBI
Cytogenetic MapXq12NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cybb
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
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Vista + UCSC

RGD Object Information
RGD ID: 620574
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-17
Status: ACTIVE