Gene: P2rx7 (purinergic receptor P2X 7) Rattus norvegicus
Symbol: P2rx7
Name: purinergic receptor P2X 7
Description: ENCODES a protein that exhibits ATP binding; channel activity; copper ion binding; INVOLVED IN apoptotic signaling pathway; bleb assembly; cell surface receptor signaling pathway; PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Epilepsy, Temporal Lobe (ortholog); Leukemia, Lymphocytic, Chronic, B-Cell (ortholog); Multiple Sclerosis (ortholog); FOUND IN bleb; cytoplasm; integral component of nuclear inner membrane; INTERACTS WITH (+)-pilocarpine; 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 2,4,6-trinitrobenzenesulfonic acid
Type: protein-coding
Also known as: ATP receptor; P2X purinoceptor 7; P2X7 purinoceptor; P2Z receptor; purinergic receptor P2X, ligand-gated ion channel, 7; purinergic receptor P2X7
Homo sapiens (human) : P2RX7 (purinergic receptor P2X 7)  HGNC  AGR
Mus musculus (house mouse) : P2rx7 (purinergic receptor P2X, ligand-gated ion channel, 7)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : P2rx7 (purinergic receptor P2X 7)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX7 (purinergic receptor P2X 7)
Canis lupus familiaris (dog) : P2RX7 (purinergic receptor P2X 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx7 (purinergic receptor P2X 7)
more info ...
Allele / Splice: P2rx7em8Mcwi  
Genetic Models: PCK-P2rx7em8Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01239,353,613 - 39,396,042 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01241,804,060 - 41,808,755 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01241,242,368 - 41,284,797 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41235,074,025 - 35,117,152 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11234,937,412 - 34,980,540 (-)NCBI
Celera1235,564,374 - 35,607,476 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on P2rx7
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3241
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-14
Status: ACTIVE