Gene: P2rx7 (purinergic receptor P2X 7) Rattus norvegicus
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Symbol: P2rx7
Name: purinergic receptor P2X 7
Description: ENCODES a protein that exhibits ATP binding; channel activity; copper ion binding; INVOLVED IN apoptotic signaling pathway; bleb assembly; cell surface receptor signaling pathway; PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH chronic lymphocytic leukemia (ortholog); CLL/SLL (ortholog); Epilepsy, Temporal Lobe (ortholog); FOUND IN bleb; cytoplasm; integral component of nuclear inner membrane; INTERACTS WITH (+)-pilocarpine; 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 2,4,6-trinitrobenzenesulfonic acid
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP receptor; P2X purinoceptor 7; P2X7 purinoceptor; P2Z receptor; purinergic receptor P2X, ligand-gated ion channel, 7; purinergic receptor P2X7
Orthologs:
Homo sapiens (human) : P2RX7 (purinergic receptor P2X 7)  HGNC
Mus musculus (house mouse) : P2rx7 (purinergic receptor P2X, ligand-gated ion channel, 7)  MGI
Chinchilla lanigera (long-tailed chinchilla) : P2rx7 (purinergic receptor P2X 7)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX7 (purinergic receptor P2X 7)
Canis lupus familiaris (dog) : P2RX7 (purinergic receptor P2X 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx7 (purinergic receptor P2X 7)
more info ...
Allele / Splice: P2rx7em8Mcwi  
Genetic Models: PCK-P2rx7em8Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01239,353,613 - 39,396,042 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01241,804,060 - 41,808,755 (-)NCBIRnor5.0rn5Rnor5.0
Rnor_5.01241,242,368 - 41,284,797 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41235,074,025 - 35,117,152 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11234,937,412 - 34,980,540 (-)NCBI
Celera1235,564,374 - 35,607,476 (-)NCBI
Cytogenetic Map12q16NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on P2rx7
NCBI Gene
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JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 3241
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-09-05
Status: ACTIVE