Gene: Map2k5 (mitogen activated protein kinase kinase 5)  Rattus norvegicus

Symbol: Map2k5
Name: mitogen activated protein kinase kinase 5
Description: ENCODES a protein that exhibits ATP binding; protein kinase activity; INVOLVED IN activation of MAPK activity; cellular response to growth factor stimulus; ERK5 cascade; PARTICIPATES IN Erk5 MAPK signaling pathway; altered Erk5 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Cardiomyopathy, Dilated (ortholog); Death, Sudden (ortholog); FOUND IN cytosol; nucleus; spindle (ortholog); INTERACTS WITH 1,1-dichloroethene; 1,2,4-trimethylbenzene; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPK/ERK kinase 5; MAPKK 5; MEK 5; Mek5; mitogen-activated protein kinase kinase 5
Orthologs: Homo sapiens : MAP2K5 (mitogen-activated protein kinase kinase 5)  HGNC
Mus musculus : Map2k5 (mitogen-activated protein kinase kinase 5)  MGI
Allele / Splice: Map2k5Tn(sb-T2/Bart3)2.150Mcwi  
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map8q24 NCBI
RGSC Genome Assembly v5.0867,784,868 - 68,009,803-NCBI
RGSC Genome Assembly v3.4867,313,472 - 67,542,723-NCBI
Rat Celera Assembly863,038,974 - 63,262,592-NCBI
Genome Assembly 3.1867,332,521 - 67,559,107-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Map2k5
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
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Vista + UCSC

RGD Object Information
RGD ID: 61890
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE