Gene: Map2k5 (mitogen activated protein kinase kinase 5) Rattus norvegicus
Symbol: Map2k5
Name: mitogen activated protein kinase kinase 5
Description: ENCODES a protein that exhibits ATP binding; protein kinase activity; INVOLVED IN activation of MAPK activity; cellular response to growth factor stimulus; ERK5 cascade; PARTICIPATES IN Erk5 MAPK signaling pathway; altered Erk5 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Cardiomyopathy, Dilated (ortholog); Death, Sudden (ortholog); FOUND IN cytosol; nucleus; spindle (ortholog); INTERACTS WITH 1,1-dichloroethene; 1,2,4-trimethylbenzene; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPK/ERK kinase 5; MAPKK 5; MEK 5; Mek5; mitogen-activated protein kinase kinase 5
Orthologs:
Allele / Splice: Map2k5Tn(sb-T2/Bart3)2.150Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0868,055,976 - 68,282,656 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0867,784,868 - 68,010,809 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4867,313,472 - 67,542,723 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1867,332,521 - 67,559,107 (-)NCBI
Celera863,038,974 - 63,262,592 (-)NCBI
Cytogenetic Map8q24NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Map2k5
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 61890
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2016-08-09
Status: ACTIVE