Gene: Cyba (cytochrome b-245 alpha chain) Rattus norvegicus
Symbol: Cyba
Name: cytochrome b-245 alpha chain
Description: ENCODES a protein that exhibits superoxide-generating NADPH oxidase activity; electron carrier activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN cellular response to amino acid stimulus; cellular response to angiotensin; cellular response to gamma radiation; PARTICIPATES IN thyroid hormone biosynthetic pathway; Leishmania infection pathway; phagocytosis pathway; ASSOCIATED WITH decreased mean systemic arterial blood pressure; ASSOCIATED WITH Diabetes Mellitus, Experimental; Diabetic Retinopathy; Eosinophilia; FOUND IN apical plasma membrane; dendrite; focal adhesion; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 11-deoxycorticosterone
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cytochrome b(558) alpha chain; cytochrome b-245 alpha chain; cytochrome b-245 light chain; cytochrome b-245, alpha polypeptide; cytochrome b558 alpha-subunit; cytochrome b558 subunit alpha; neutrophil cytochrome b 22 kDa polypeptide; p22 phagocyte B-cytochrome; p22-phox; p22phox; superoxide-generating NADPH oxidase light chain subunit
Orthologs:
Allele / Splice: Cybaem1Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01955,249,634 - 55,257,824 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01965,959,818 - 65,967,224 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41952,713,150 - 52,721,609 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11952,718,030 - 52,726,490 (-)NCBI
Celera1949,727,142 - 49,735,154 (-)NCBI
Cytogenetic Map19q12NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Cyba
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 620573
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-04-12
Status: ACTIVE