Gene: Cyba (cytochrome b-245, alpha polypeptide) Rattus norvegicus
Symbol: Cyba
Name: cytochrome b-245, alpha polypeptide
Description: ENCODES a protein that exhibits superoxide-generating NADPH oxidase activity; electron carrier activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN cellular response to amino acid stimulus; cellular response to gamma radiation; cellular response to glucose stimulus; PARTICIPATES IN Leishmania infection pathway; phagocytosis pathway; ASSOCIATED WITH decreased mean systemic arterial blood pressure; ASSOCIATED WITH Diabetes Mellitus, Experimental; Diabetic Retinopathy; Hypertension; FOUND IN apical plasma membrane; dendrite; Golgi apparatus; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 11-deoxycorticosterone; 17alpha-ethynylestradiol
Type: protein-coding
Also known as: cytochrome b(558) alpha chain; cytochrome b-245 light chain; cytochrome b558 alpha-subunit; cytochrome b558 subunit alpha; neutrophil cytochrome b 22 kDa polypeptide; p22 phagocyte B-cytochrome; p22-phox; p22phox; superoxide-generating NADPH oxidase light chain subunit
Allele / Splice: Cybaem1Mcwi  
Latest Assembly: RGSC Genome Assembly v5.0
NCBI Annotation Information: Annotation category: partial on reference assembly
RGSC Genome Assembly v6.01955,249,634 - 55,257,824-NCBI
Rat Cytogenetic Map19q12 NCBI
RGSC Genome Assembly v5.01965,959,818 - 65,967,224-NCBI
RGSC Genome Assembly v3.41952,713,150 - 52,721,609-NCBI
Rat Celera Assembly1949,727,142 - 49,735,154-NCBI
Genome Assembly 3.11952,718,030 - 52,726,490-NCBI

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Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Cyba
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RGD Object Information
RGD ID: 620573
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2015-11-09
Status: ACTIVE