Gene: Cyba (cytochrome b-245 alpha chain) Rattus norvegicus
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Symbol: Cyba
Name: cytochrome b-245 alpha chain
Description: ENCODES a protein that exhibits superoxide-generating NADPH oxidase activity; electron transfer activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN cellular response to amino acid stimulus; cellular response to angiotensin; cellular response to gamma radiation; PARTICIPATES IN thyroid hormone biosynthetic pathway; Leishmania infection pathway; phagocytosis pathway; ASSOCIATED WITH abnormal superoxide dismutase level; absent otoliths; decreased mean systemic arterial blood pressure; ASSOCIATED WITH Diabetes Mellitus, Experimental; Diabetic Retinopathy; diabetic retinopathy; FOUND IN apical plasma membrane; dendrite; focal adhesion; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 11-deoxycorticosterone
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-subunit p22; cytochrome b(558) alpha chain; cytochrome b-245 light chain; cytochrome b-245, alpha polypeptide; cytochrome b558 alpha-subunit; cytochrome b558 subunit alpha; neutrophil cytochrome b 22 kDa polypeptide; p22 phagocyte B-cytochrome; p22-phox; p22phox; Phox; superoxide-generating NADPH oxidase light chain subunit
Orthologs:
Homo sapiens (human) : CYBA (cytochrome b-245 alpha chain)  HGNC  AGR
Mus musculus (house mouse) : Cyba (cytochrome b-245, alpha polypeptide)  MGI
Chinchilla lanigera (long-tailed chinchilla) : LOC102004641 (cytochrome b-245 light chain)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100986914 (cytochrome b-245 light chain)
Canis lupus familiaris (dog) : CYBA (cytochrome b-245, alpha polypeptide)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101967032 (cytochrome b-245 light chain)
more info ...
Allele / Splice: Cybaem1Mcwi   Cybam1Sdi  
Genetic Models: MES/Slc SS-Cybaem1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01955,249,634 - 55,257,824 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01965,959,818 - 65,967,224 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41952,713,150 - 52,721,609 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11952,718,030 - 52,726,490 (-)NCBI
Celera1949,727,142 - 49,735,154 (-)NCBI
Cytogenetic Map19q12NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Cyba
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 620573
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE