ONTOLOGY BROWSER
| Term: | lamivudine |
|
| Accession: | CHEBI:63577
|
 browse the term
 view annotations
|
| Definition: | A monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase. |
| Synonyms: | exact_synonym: | 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one |
| | related_synonym: | (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine; (-)-2'-Deoxy-3'-thiacytidine; 2',3'-Dideoxy-3'-thiacytidine; 3'-Thia-2',3'-dideoxycytidine; 3TC; C8H11N3O3S; Epivir; InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1; InChIKey=JTEGQNOMFQHVDC-NKWVEPMBSA-N; Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1; beta-L-2',3'-Dideoxy-3'-thiacytidine; beta-L-3'-Thia-2',3'-dideoxycytidine |
| | alt_id: | CHEBI:6366 |
| | xref_casrn: | 134678-17-4 |
| | xref: | ChEMBL:133986 "ChEMBL COMPOUND"; ChemIDplus:134678-17-4 "CAS Registry Number"; CiteXplore:21465499 "PubMed citation"; CiteXplore:21721935 "PubMed citation"; CiteXplore:21851334 "PubMed citation"; CiteXplore:22001270 "PubMed citation"; CiteXplore:22028068 "PubMed citation"; CiteXplore:22078148 "PubMed citation"; CiteXplore:22085635 "PubMed citation"; CiteXplore:22097898 "PubMed citation"; CiteXplore:22098177 "PubMed citation"; CiteXplore:22170540 "PubMed citation"; CiteXplore:22211086 "PubMed citation"; CiteXplore:22222724 "PubMed citation"; CiteXplore:22226087 "PubMed citation"; CiteXplore:22231575 "PubMed citation"; CiteXplore:22233654 "PubMed citation"; DrugBank:DB00709 "DrugBank"; KEGG COMPOUND:134678-17-4 "CAS Registry Number"; KEGG COMPOUND:C07065 "KEGG COMPOUND"; KEGG DRUG:D00353 "KEGG DRUG" |
| | xref_mesh: | MESH:D019259 |
| | xref: | Patent:WO9117159 "Patent"; Reaxys:5480511 "Reaxys Registry Number"; Wikipedia:Lamivudine "Wikipedia" |
|
|
| Parent Terms |
Term With Siblings |
Child Terms |
|
|
(+)-artemisinic alcohol +
(+)-calanolide A
(+)-lariciresinol
(+)-lyoniresinol +
(+)-lyoniresinol 4,4'-bis-O-beta-D-glucopyranoside
(+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside
(-)-annonaine +
(-)-calanolide B
(-)-carbovir +
(20R)-28-hydroxylupen-30-al-3-one
(3,4-dimethoxyphenyl)methanol
(3Z,6Z,9Z)-dodecatrienol
(E,E)-2-methyl-6-oxohepta-2,4-dienol
(Z)-hex-3-en-1-ol +
1,2-dinitroglycerol
1-(2,3-dideoxy-6-O-phosphono-beta-D-erythro-hexopyranosyl)cytosine
1-(2-deoxy-2-fluoro-5-O-phosphono-beta-D-arabinofuranosyl)cytosine
1-(5-\{[3-(1H-benzimidazol-2-yl)propanoyl]amino\}-5-deoxy-alpha-L-lyxofuranosyl)cytosine
1-[(1S,2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)bicyclo[3.1.0]hexan-2-yl]thymine
1-[(1S,3S,4R,5S)-3-hydroxy-4-(hydroxymethyl)bicyclo[3.1.0]hexan-1-yl]thymine
1-[(2-hydroxyethoxy)methyl]-6-(phenylsulfanyl)thymine
1-hydroxy-5-phenyl-3-pentanone
1-methylcytosine
10-deoxysarpagine
12-deoxyphorbol-13-(3E,5E-decadienoate)
16beta,17-dihydroxy-ent-kaurane-19-oic acid
17alpha(H),21beta(H)-bishomohopanol
17beta(H),21beta(H)-bishomohopanol
1beta-hydroxymaprounic acid 3-p-hydroxybenzoate
2'-deoxycytidine +
2-(2,4-dihydroxy-5-prenylphenyl)-5,6-methylenedioxybenzofuran
2-(hydroxymethyl)-4-(1-hydroxy-2-\{[6-(4-phenylbutoxy)hexyl]amino\}ethyl)phenol +
2-(morpholin-4-yl)ethanol +
2-(piperidin-1-yl)ethanol +
2-butoxyethanol
2-ethylhexan-1-ol +
2-methylbutan-1-ol +
2-methylthioethanol
2-O-methylcytosine
2-phenylethanol +
20-epi-isoiguesterinol
2alpha-hydroxymaprounic acid 2,3-bis-p-hydroxybenzoate
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol
3,N(4)-ethenocytosine
3-(acetamidomethylidene)-2-(hydroxymethyl)succinic acid
3-hydroxymethyl-4-methyl-furan-2(5H)-one
3-methylcytosine
3-O-trans-p-coumaroyl actinidic acid
4-amino-1-[2,5-anhydro-4-(hydroxymethyl)-alpha-L-lyxofuranosyl]-5-methylcytosine
4-hydroxycinnamyl alcohol +
4-methylpentan-1-ol
5-benzyl-1-(2-hydroxyethoxymethyl)uracil
5-benzyloxybenzylacyclouridine
5-fluoro-2'-deoxyuridine
5-hydroxymethyluracil
5-iodo-2'-deoxyuridine
5-methylcytosine +
6,6'-bieckol
6-(3-hydroxypropyl)thymine
6-\{[(4R,5R)-4-(hydroxymethyl)thymin-5-yl]methyl\}thymine
7'-hydroxyabscisic acid
7-oxohernangerine
8'-epi-cleomiscosin A
8-amino-2,12-dihydroxy-4a,9-dihydro[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one 2-oxide
9beta-pimara-7,15-dien-19-ol
[3-(2,2,3-trimethylcyclopent-3-enyl)cyclohex-3-enyl]methanol
[4-(2,2,3-trimethylcyclopent-3-enyl)cyclohex-3-enyl]methanol
abacavir +
acyclovir
alismorientol A
amantadine
amprenavir
andrographolide
anolignan A
anolignan B
aphidicolin
aplysinoplide A
aplysinoplide B
aplysinoplide C
aromatic primary alcohol +
atazanavir +
azulenofuran +
BE-24566B
benserazide
benzochromene +
benzodioxine +
benzodioxoles +
benzofurans +
benzofurofurochromene
benzofuropyranochromene +
benzopyran +
benzoxadiazole +
benzoxathiin +
benzoxathiine +
benzoxathiole +
benzoxazine +
benzoxazole +
bicoumarin +
bidebiline C
bidebiline D
bidenlignaside A
boceprevir
bosentan +
butan-1-ol
butyn-1-ols +
carbovir +
celasdin B
chanoclavine-I +
cidofovir anhydrous +
cidofovir dihydrate
cimifoetiside A
cimifoetiside B
cinnamyl alcohol +
clathsterol
clathsterol disulfonic acid
cleomiscosin A
clopenthixol +
costunolide
crotyl alcohol +
cyclic ether +
cyclic ketal +
cycloheptafuran +
cyclohexadienol +
cyclopentacyclononaoxirene +
cyclopentafuran +
cyclopentafurofurochromene +
cyclopentapyran +
cytarabine
cytidine +
cytidines +
cytosin1-yl group
cytosine glycol
cytosporic acid
daedalin A
daidzein +
darunavir
delavirdine +
delavirdine mesylate
deoxylimonoic acid D-ring-lactone
dibenzodioxocine +
dibenzodioxonine +
dibenzofurans +
dibenzopyran +
dicerandrol A
dicerandrol B
didanosine
dieckol
dimercaprol
dioxanes +
dioxolane +
docebenone
dodecanol +
drimenol
eckstolonol
efavirenz
emivirine
emtricitabine
entecavir (anhydrous) +
entecavir hydrate
ethanol +
ethanols +
etravirine
everolimus
famciclovir
farnesol +
flucytosine
flupenthixol
furans +
furfuryl alcohol +
furochromene +
furodioxole +
furofuran +
furonaphthodioxole +
furopyridine +
furopyrimidine +
furopyrrole +
ganciclovir +
ganoderone A
ganoderone C
gemcitabine +
gemcitabine hydrochloride
geraniol +
glomosporin
glycidol +
glycolic acid +
hentriacontan-1-ol
hernandonine
hexadecen-1-ols +
HIV fusion inhibitor +
hydroxytyrosol +
imidazole-4-methanol
imidazooxazine +
indicanone
indolyl alcohol +
isoamylol +
isobutanol +
isopentenyl alcohol +
isotanshinone IIB
jaspamide L
kadsuphilactone B
lactone +
lamivudine A monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase.
lindechunine A
liriodenine
loxtidine
lyratol C
maprounic acid +
maraviroc
marianoside A
mercaptoethanol +
methanol +
methyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate
methyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate
methyl 5-(hydroxymethyl)pyrrolidine-2-carboxylate
methyl 5-(hydroxymethyl)pyrrolidine-3-carboxylate
metronidazole +
molybdopterin synthase intermediate
monothioketal +
myriaporone 3
N(4)-methylcytosine
N-(hydroxymethyl)phthalimide +
N-[(cytosin-1-yl)acetyl]-N-[2-(methylamino)ethyl]glycine
N-acetyl-L-cysteine +
N-acetylneuraminol +
naphtho-gamma-pyrone +
naphthochromene +
naphthofuran +
naphthoisochromene +
negundin B
neobavaisoflavone +
neuraminidase inhibitor +
nevirapine
nigranoic acid
oblonganoside A
octadienol +
octan-1-ol
ophioglonin
oseltamivir +
oseltamivir acid
ospemifene
oxabicycloalkane +
oxacyclopentaindacene +
oxadiazane +
oxadiazole +
oxadiazolidine +
oxanes +
oxanthrene
oxatetracycloalkane +
oxazinane +
oxazole +
oxazolidines +
oxazolopyrazine +
oxazolopyridine +
oxazolopyrimidine +
oxetanes +
oxetenes +
oxirene
oxolanes +
penciclovir
pentalen-13-ol
pentan-1-ol
penten-1-ols +
phosphonoformic acid
plaunotol
precursor Z
precursor Z hydrate
propan-1-ols +
propenol +
propynol +
prosolanapyrone II
pyranoindolizinoquinoline +
pyranopterin +
pyranopyridine +
pyranothiazole +
pyranoxanthones +
pyrans +
pyridophenoxazine +
pyrimidobenzoxazine +
rilpivirine
rilpivirine hydrochloride
robustaflavone +
rotenonone
salaspermic acid
salicin +
salutaridine
saquinavir
sarpagine +
scalusamide A
sch 725432
schisanwilsonene A
sinapyl alcohol +
solanapyrone A
sterigmatocystins +
sulfocholine +
swertipunicoside
telaprevir
telbivudine
tenofovir (anhydrous) +
tenofovir disoproxil +
tenofovir disoproxil fumarate
tenofovir hydrate
terpenol +
thienopyran +
tipranavir
TMC-86A
TMC-86B
TMC-89A
TMC-89B
TMC-96
tolypodiol
trans-2,3-epoxydeca-4,6,8-triyn-1-ol
trioxane +
trisodium phosphonoformate +
trisodium phosphonoformate hexahydrate
valacyclovir
valganciclovir
vinylamycin
zalcitabine
zidovudine
zymosterol intermediate 1a
|
|
|
|
|
