Gene: Bdnf (brain-derived neurotrophic factor) Rattus norvegicus
Symbol: Bdnf
Name: brain-derived neurotrophic factor
Description: ENCODES a protein that exhibits neurotrophin TRKB receptor binding; INVOLVED IN cellular response to nerve growth factor stimulus; cellular response to norepinephrine stimulus; cellular response to tumor necrosis factor; PARTICIPATES IN Huntington disease pathway; mitogen activated protein kinase signaling pathway; neurotrophic factor signaling pathway; ASSOCIATED WITH increased alcohol consumption; increased anxiety-related response; ASSOCIATED WITH Alzheimer Disease; Attention Deficit Disorder with Hyperactivity; Brain Injuries; FOUND IN axon; dendrite; extracellular space; INTERACTS WITH (+)-catechin; (+)-pilocarpine; (-)-epigallocatechin 3-gallate
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Brain derived neurothrophic factor; brain derived neurotrophic factor; MGC105254
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.03100,768,637 - 100,819,216+NCBI
Rat Cytogenetic Map3q33 NCBI
RGSC Genome Assembly v5.03107,371,329 - 107,421,908+NCBI
Rat Celera Assembly395,191,318 - 95,241,949+NCBI

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Disease Annotations
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Gene Ontology Annotations
Molecular Pathway Annotations
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References - curated
References - uncurated
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Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Bdnf
Entrez Gene
Ensembl Gene
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Vista + UCSC

RGD Object Information
RGD ID: 2202
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-11-10
Status: ACTIVE