Gene: Aars (alanyl-tRNA synthetase) Rattus norvegicus
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Symbol: Aars
Name: alanyl-tRNA synthetase
Description: ENCODES a protein that exhibits alanine-tRNA ligase activity; amino acid binding; ATP binding; INVOLVED IN alanyl-tRNA aminoacylation; cerebellar Purkinje cell layer development (ortholog); negative regulation of neuron apoptotic process (ortholog); PARTICIPATES IN alanine metabolic pathway; lactic acidosis pathway; primary hyperoxaluria type 1 disease pathway; ASSOCIATED WITH Charcot-Marie-Tooth Disease (ortholog); Charcot-Marie-Tooth disease type 2 (ortholog); Charcot-Marie-Tooth Disease, Axonal, Type 2N (ortholog); FOUND IN cytoplasm; cytosol (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alanine--tRNA ligase; alanine--tRNA ligase, cytoplasmic; alanyl-tRNA synthetase, cytoplasmic; alaRS; LOC292023
Orthologs:
Homo sapiens (human) : AARS (alanyl-tRNA synthetase)  HGNC  AGR
Mus musculus (house mouse) : Aars (alanyl-tRNA synthetase)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Aars (alanyl-tRNA synthetase)
Pan paniscus (bonobo/pygmy chimpanzee) : AARS (alanyl-tRNA synthetase)
Canis lupus familiaris (dog) : AARS (alanyl-tRNA synthetase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aars (alanyl-tRNA synthetase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01943,193,264 - 43,215,281 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01954,018,025 - 54,040,573 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,952,408 - 40,974,425 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11940,957,348 - 40,979,299 (+)NCBI
Celera1938,390,301 - 38,412,318 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Aars
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304832
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE