| (3S,5R)-fluvastatin | multiple interactions | ISO | RGD:736202 | 6480464 | [zoledronic acid co-treated with fluvastatin] results in increased expression of OPTN mRNA | CTD | PMID:16996129 |
| 17beta-estradiol | decreases expression | ISO | RGD:736202 | 6480464 | Estradiol results in decreased expression of OPTN mRNA | CTD | PMID:23019147 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:736202 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of OPTN mRNA | CTD | PMID:20106945 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:736202 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of OPTN mRNA | CTD | PMID:20106945 PMID:21632981 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:733470 | 6480464 | Tetrachlorodibenzodioxin affects the expression of OPTN mRNA | CTD | PMID:21570461 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of OPTN mRNA | CTD | PMID:21215274 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of OPTN mRNA | CTD | PMID:22298810 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of OPTN mRNA] | CTD | PMID:21215274 |
| 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of OPTN mRNA | CTD | PMID:21346803 |
| 2-butoxyethanol | increases expression | ISO | RGD:733470 | 6480464 | n-butoxyethanol results in increased expression of OPTN mRNA | CTD | PMID:19812364 |
| 5-fluorouracil | affects response to substance | ISO | RGD:736202 | 6480464 | OPTN protein affects the susceptibility to Fluorouracil | CTD | PMID:16217747 |
| 5-fluorouracil | increases expression | ISO | RGD:736202 | 6480464 | Fluorouracil results in increased expression of OPTN mRNA | CTD | PMID:16101138 PMID:17039268 |
| 5-fluorouracil | increases expression | ISO | RGD:736202 | 6480464 | Fluorouracil results in increased expression of OPTN mRNA | CTD | PMID:17039268 PMID:16101138 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of OPTN mRNA | CTD | PMID:16483693 |
| benzo[a]pyrene | increases expression | ISO | RGD:736202 | 6480464 | Benzo(a)pyrene results in increased expression of OPTN mRNA | CTD | PMID:22316170 |
| calcitriol | increases expression | ISO | RGD:736202 | 6480464 | Calcitriol results in increased expression of OPTN mRNA | CTD | PMID:21592394 |
| calcitriol | multiple interactions | ISO | RGD:736202 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of OPTN mRNA | CTD | PMID:21592394 |
| ciglitazone | multiple interactions | ISO | RGD:736202 | 6480464 | [ciglitazone binds to PPARG protein alternative form] which results in increased expression of OPTN mRNA; more ... | CTD | PMID:16197558 |
| cisplatin | multiple interactions | ISO | RGD:736202 | 6480464 | Cisplatin affects the reaction [Piroxicam results in decreased expression of OPTN mRNA] | CTD | PMID:21858171 |
| cisplatin | affects response to substance | ISO | RGD:736202 | 6480464 | OPTN protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 |
| clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of OPTN mRNA | CTD | PMID:17602206 |
| cobalt dichloride | increases expression | ISO | RGD:736202 | 6480464 | cobaltous chloride results in increased expression of OPTN mRNA | CTD | PMID:19320972 PMID:19376846 |
| copper atom | multiple interactions | ISO | RGD:736202 | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of OPTN mRNA | CTD | PMID:20971185 |
| copper(0) | multiple interactions | ISO | RGD:736202 | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of OPTN mRNA | CTD | PMID:20971185 |
| copper(2+) sulfate | increases expression | ISO | RGD:736202 | 6480464 | Copper Sulfate results in increased expression of OPTN mRNA | CTD | PMID:19549813 |
| coumestrol | multiple interactions | ISO | RGD:736202 | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of OPTN mRNA | CTD | PMID:19167446 |
| coumestrol | decreases expression | ISO | RGD:736202 | 6480464 | Coumestrol results in decreased expression of OPTN mRNA | CTD | PMID:19167446 |
| cyclosporin A | increases expression | ISO | RGD:736202 | 6480464 | Cyclosporine results in increased expression of OPTN mRNA | CTD | PMID:20106945 |
| dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of OPTN mRNA | CTD | PMID:21266533 |
| elemental selenium | increases expression | ISO | RGD:736202 | 6480464 | Selenium results in increased expression of OPTN mRNA | CTD | PMID:19244175 |
| hyaluronic acid | multiple interactions | EXP | | 6480464 | Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of OPTN protein] | CTD | PMID:23178681 |
| hydrogen peroxide | multiple interactions | EXP | | 6480464 | Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of OPTN protein] | CTD | PMID:23178681 |
| hydrogen peroxide | decreases expression | EXP | | 6480464 | Hydrogen Peroxide results in decreased expression of OPTN protein | CTD | PMID:23178681 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of OPTN mRNA | CTD | PMID:17602206 |
| nickel dichloride | increases expression | ISO | RGD:736202 | 6480464 | nickel chloride results in increased expression of OPTN mRNA | CTD | PMID:17312168 |
| paracetamol | decreases expression | ISO | RGD:736202 | 6480464 | Acetaminophen results in decreased expression of OPTN mRNA | CTD | PMID:21420995 |
| perfluorooctane-1-sulfonic acid | increases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in increased expression of OPTN mRNA | CTD | PMID:18692542 |
| pirinixic acid | increases expression | ISO | RGD:733470 | 6480464 | pirinixic acid results in increased expression of OPTN mRNA | CTD | PMID:18301758 |
| pirinixic acid | multiple interactions | ISO | RGD:733470 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of OPTN mRNA | CTD | PMID:19710929 |
| piroxicam | decreases expression | ISO | RGD:736202 | 6480464 | Piroxicam results in decreased expression of OPTN mRNA | CTD | PMID:21858171 |
| piroxicam | multiple interactions | ISO | RGD:736202 | 6480464 | Cisplatin affects the reaction [Piroxicam results in decreased expression of OPTN mRNA] | CTD | PMID:21858171 |
| propiconazole | decreases expression | ISO | RGD:733470 | 6480464 | propiconazole results in decreased expression of OPTN mRNA | CTD | PMID:21278054 |
| rel-(3R,5S)-fluvastatin | multiple interactions | ISO | RGD:736202 | 6480464 | [zoledronic acid co-treated with fluvastatin] results in increased expression of OPTN mRNA | CTD | PMID:16996129 |
| selenium atom | increases expression | ISO | RGD:736202 | 6480464 | Selenium results in increased expression of OPTN mRNA | CTD | PMID:19244175 |
| tamoxifen | affects expression | ISO | RGD:736202 | 6480464 | Tamoxifen affects the expression of OPTN mRNA | CTD | PMID:14699072 |
| testosterone | increases expression | ISO | RGD:736202 | 6480464 | Testosterone results in increased expression of OPTN mRNA | CTD | PMID:21592394 |
| testosterone | multiple interactions | ISO | RGD:736202 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of OPTN mRNA | CTD | PMID:21592394 |
| tetrachloromethane | affects expression | ISO | RGD:733470 | 6480464 | Carbon Tetrachloride affects the expression of OPTN mRNA | CTD | PMID:17484886 |
| toluene | decreases expression | EXP | | 6480464 | Toluene results in decreased expression of OPTN mRNA | CTD | PMID:22166486 |
| topotecan | affects response to substance | ISO | RGD:736202 | 6480464 | OPTN protein affects the susceptibility to Topotecan | CTD | PMID:16217747 |
| zoledronic acid | multiple interactions | ISO | RGD:736202 | 6480464 | [zoledronic acid co-treated with fluvastatin] results in increased expression of OPTN mRNA | CTD | PMID:16996129 |