GENE - CHEMICAL INTERACTIONS REPORT
RGD ID:
69328
Species:
Rattus norvegicus
RGD Object:
Gene
Symbol:
Cdkn1a
Name:
cyclin-dependent kinase inhibitor 1A
Acc ID:
CHEBI:2038
Term:
5-azacytidine
Definition:
A N-glycosyl-1,3,5-triazine that has formula C8H12N4O5.
CasRN:
320-67-2
Chemical ID:
MESH:D001374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
increases expression ISO RGD:735341 6480464 CTD Azacitidine analog results in increased expression of CDKN1A protein PMID:18324645 increases expression ISO RGD:735341 6480464 CTD Azacitidine results in increased expression of CDKN1A protein Azacitidine results in increased expression of CDKN1A mRNA PMID:15547111 multiple interactions ISO RGD:735341 6480464 CTD [metacept-1 co-treated with Azacitidine] results in increased expression of CDKN1A PMID:19148494 multiple interactions ISO RGD:735341 6480464 CTD pifithrin inhibits the reaction [Azacitidine results in increased expression of CDKN1A mRNA] pifithrin inhibits the reaction [Azacitidine results in increased expression of CDKN1A protein] PMID:15547111 increases expression EXP 6480464 CTD Azacitidine results in increased expression of CDKN1A mRNA PMID:21224363 multiple interactions EXP 6480464 CTD [Azacitidine co-treated with N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide] results in increased expression of CDKN1A mRNA [Azacitidine co-treated with entinostat] results in increased expression of CDKN1A mRNA PMID:21224363