Gene: Cftr (cystic fibrosis transmembrane conductance regulator) Rattus norvegicus
Symbol: Cftr
Name: cystic fibrosis transmembrane conductance regulator
Description: ENCODES a protein that exhibits bicarbonate transmembrane transporter activity (ortholog); chloride channel activity (ortholog); chloride channel inhibitor activity (ortholog); INVOLVED IN bicarbonate transport; cellular response to hormone stimulus; chloride transport; PARTICIPATES IN bile acid transport pathway; ASSOCIATED WITH Cholestasis; Duodenal Ulcer; Myocardial Ischemia; FOUND IN apical plasma membrane; basolateral plasma membrane; cytoplasm; INTERACTS WITH 17beta-estradiol; 3',5'-cyclic AMP; 3-isobutyl-1-methyl-7H-xanthine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; cAMP-dependent chloride channel; channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulator homolog; cystic fibrosis transmembrane conductance regulator homolog (human); LOC500041; RGD1561193; similar to cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)
Orthologs:
Is Marker For: Strains:   BB/OK  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0442,693,263 - 42,860,679 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0442,281,040 - 42,448,571 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4443,874,852 - 44,041,870 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1444,147,212 - 44,195,889 (+)NCBI
Celera441,826,966 - 41,988,614 (+)NCBI
Cytogenetic Map4q21NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cftr
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2332
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-08-16
Status: ACTIVE