Gene: Cftr (cystic fibrosis transmembrane conductance regulator)  Rattus norvegicus
Symbol: Cftr
Name: cystic fibrosis transmembrane conductance regulator
Description: ENCODES a protein that exhibits chloride channel activity (ortholog); chloride channel inhibitor activity (ortholog); enzyme binding (ortholog); INVOLVED IN bicarbonate transport; cellular response to hormone stimulus; chloride transport; PARTICIPATES IN bile acid transport pathway; ASSOCIATED WITH Cholestasis; Duodenal Ulcer; Myocardial Ischemia; FOUND IN apical plasma membrane; basolateral plasma membrane; cytoplasm; INTERACTS WITH 3',5'-cyclic AMP; 3-isobutyl-1-methyl-7H-xanthine; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; cAMP-dependent chloride channel; channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulator; cystic fibrosis transmembrane conductance regulator homolog; cystic fibrosis transmembrane conductance regulator homolog (human); LOC500041; RGD1561193; RGD1561193_predicted; similar to cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7); similar to cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) (predicted)
Orthologs: Homo sapiens : CFTR (cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7))  HGNC
Mus musculus : Cftr (cystic fibrosis transmembrane conductance regulator)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map4q21 NCBI
RGSC Genome Assembly v5.0442,281,456 - 42,448,568+NCBI
RGSC Genome Assembly v3.4443,874,852 - 44,041,870+NCBI
Rat Celera Assembly441,826,966 - 41,988,614+NCBI
Genome Assembly 3.1444,147,212 - 44,195,889+NCBI
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RGD Object Information
RGD ID: 2332
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE



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