Gene: Cftr (cystic fibrosis transmembrane conductance regulator) Rattus norvegicus
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Symbol: Cftr
Name: cystic fibrosis transmembrane conductance regulator
Description: ENCODES a protein that exhibits ATPase activity (ortholog); bicarbonate transmembrane transporter activity (ortholog); chloride channel activity (ortholog); INVOLVED IN aging; bicarbonate transport; cellular response to anoxia; PARTICIPATES IN bile acid transport pathway; ASSOCIATED WITH abnormal chloride level; abnormal circulating protein level; abnormal nasal mucosa morphology; ASSOCIATED WITH acute gonococcal salpingitis; acute salpingitis; acute salpingo-oophoritis; FOUND IN apical plasma membrane; basolateral plasma membrane; cytoplasm; INTERACTS WITH 17beta-estradiol; 3',5'-cyclic AMP; 3-isobutyl-1-methyl-7H-xanthine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; cAMP-dependent chloride channel; channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulator homolog; cystic fibrosis transmembrane conductance regulator homolog (human); LOC500041; RGD1561193; similar to cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)
Orthologs:
Homo sapiens (human) : CFTR (cystic fibrosis transmembrane conductance regulator)  HGNC  AGR
Mus musculus (house mouse) : Cftr (cystic fibrosis transmembrane conductance regulator)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Cftr (cystic fibrosis transmembrane conductance regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : CFTR (cystic fibrosis transmembrane conductance regulator)
Canis lupus familiaris (dog) : CFTR (cystic fibrosis transmembrane conductance regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cftr (cystic fibrosis transmembrane conductance regulator)
more info ...
Is Marker For: Strains:   BB/OK  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0442,693,263 - 42,860,679 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0442,281,040 - 42,448,571 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4443,874,852 - 44,041,870 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1444,147,212 - 44,195,889 (+)NCBI
Celera441,826,966 - 41,988,614 (+)NCBI
Cytogenetic Map4q21NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences