RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: liver cirrhosis
Accession: DOID:5082
browse the term
Definition: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
Synonyms: exact_synonym: Hepatic Cirrhosis; Hepatic Fibrosis; cirrhosis; cirrhosis of liver; hepatic cirrhoses; liver cirrhoses; liver fibroses; liver fibrosis
primary_id: MESH:D008103
xref: EFO:0001422 ; ICD10CM:K74.60 ; NCI:C2951
For additional species annotation, visit the
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Abcb11
ATP binding cassette subfamily B member 11
severity
ISO
associated with Hepatitis C, Chronic;DNA:SNP:cds:1331T>C, p.V444A,(rs2287622)(human)
RGD
PMID:29755014
RGD:14402415
NCBI chrNW_004624787:6,653,849...6,733,058
Ensembl chrNW_004624787:6,650,772...6,733,195
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Ace
angiotensin I converting enzyme
no_association severity treatment
ISO
associated with liver disease;DNA:insertion/deletion: associated with hepatitis C;DNA:insertion/deletion: associated with Chronic Hepatitis B;protein:increased expression:blood serum (human)
RGD
PMID:19456900 PMID:26681055 PMID:28822808 PMID:29085215 PMID:29335866
RGD:11537135 RGD:25671453 RGD:25671454 RGD:39939123 RGD:40400898
NCBI chrNW_004624849:998,262...1,019,305
Ensembl chrNW_004624849:998,277...1,019,521
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Acta2
actin alpha 2, smooth muscle
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24239723 PMID:24321339 PMID:30097701 PMID:32659284
NCBI chrNW_004624791:15,243,074...15,259,362
Ensembl chrNW_004624791:15,242,432...15,259,508
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Adamts13
ADAM metallopeptidase with thrombospondin type 1 motif 13
severity
ISO
protein:increased expression, increased activity:liver (rat)
RGD
PMID:16689760
RGD:1598737
NCBI chrNW_004624760:1,865,474...1,889,394
Ensembl chrNW_004624760:1,865,376...1,889,203
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Adar
adenosine deaminase RNA specific
ameliorates
ISO
associated with human immunodeficiency virus infectious disease, hepatitis C;DNA:SNPs:exon 2, 3' utr:multiple (human)
RGD
PMID:29018269
RGD:125097516
NCBI chrNW_004624885:2,783,058...2,839,688
Ensembl chrNW_004624885:2,812,448...2,839,693
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Adipoq
adiponectin, C1Q and collagen domain containing
severity
ISO
protein:increased expression:plasma
RGD
PMID:16115302
RGD:5686674
NCBI chrNW_004624730:69,941,963...69,959,266
Ensembl chrNW_004624730:69,941,001...69,957,012
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Adipor2
adiponectin receptor 2
ISO
mRNA:decreased expression:liver (mouse)
RGD
PMID:17006986
RGD:1599139
NCBI chrNW_004624735:11,103,082...11,174,277
Ensembl chrNW_004624735:11,103,076...11,174,337
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Adra1a
adrenoceptor alpha 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16782692
NCBI chrNW_004624758:21,557,161...21,665,432
Ensembl chrNW_004624758:21,569,908...21,665,244
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Ager
advanced glycosylation end-product specific receptor
ISO
mRNA:decreased expression:lung (liver)
RGD
PMID:22669512
RGD:7245533
NCBI chrNW_004624754:24,138,086...24,140,900
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Agt
angiotensinogen
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15613622 PMID:21873937
RGD:8549465
NCBI chrNW_004624775:18,846,222...18,856,093
Ensembl chrNW_004624775:18,849,118...18,855,577
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Ahr
aryl hydrocarbon receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29416063
NCBI chrNW_004624739:12,939,183...12,987,574
Ensembl chrNW_004624739:12,942,165...12,987,973
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Akap12
A-kinase anchoring protein 12
ISO
mRNA,protein:increased expression:liver
RGD
PMID:23925424
RGD:14348971
NCBI chrNW_004624785:6,900,252...6,987,712
Ensembl chrNW_004624785:6,897,561...6,988,287
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Alad
aminolevulinate dehydratase
ISO
CTD Direct Evidence: marker/mechanism protein:decreased activity:liver (human)
CTD RGD
PMID:6848403 PMID:25226513
RGD:15042852
NCBI chrNW_004624760:21,698,689...21,709,907
Ensembl chrNW_004624760:21,698,587...21,711,822
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Alb
albumin
disease_progression
ISO
CTD Direct Evidence: marker/mechanism associated with Head and Neck Neoplasms;
CTD RGD
PMID:17977396 PMID:21851314 PMID:23285146
RGD:11035282
NCBI chrNW_004624735:34,105,237...34,123,479
Ensembl chrNW_004624735:34,104,537...34,123,624
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Anks6
ankyrin repeat and sterile alpha motif domain containing 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23793029
NCBI chrNW_004624825:2,157,158...2,214,115
Ensembl chrNW_004624825:2,157,158...2,212,971
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Apoa1
apolipoprotein A1
ISO
protein:decreased expression:serum (human)
RGD
PMID:27106140
RGD:25671439
NCBI chrNW_004624784:12,249,283...12,251,215
Ensembl chrNW_004624784:12,249,283...12,251,136
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Arnt
aryl hydrocarbon receptor nuclear translocator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22271822
NCBI chrNW_004624772:18,949,221...19,016,672
Ensembl chrNW_004624772:18,949,108...19,015,504
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Arrb1
arrestin beta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624817:1,750,448...1,828,399
Ensembl chrNW_004624817:1,750,156...1,823,309
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Arrb2
arrestin beta 2
ISO
protein:increased expression:hepatic artery
RGD
PMID:17256744
RGD:1625784
NCBI chrNW_004624786:8,568,102...8,576,445
Ensembl chrNW_004624786:8,568,198...8,577,914
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Atg5
autophagy related 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33549628
NCBI chrNW_004624780:15,987,483...16,124,158
Ensembl chrNW_004624780:15,987,397...16,124,151
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Atm
ATM serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:36526012
NCBI chrNW_004624784:2,933,172...3,080,131
Ensembl chrNW_004624784:2,937,499...3,078,216
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Atp7b
ATPase copper transporting beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25134866
NCBI chrNW_004624748:2,112,574...2,183,994
Ensembl chrNW_004624748:2,113,094...2,205,856
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Axin1
axin 1
ISO
protein:decreased expression:liver (human)
RGD
PMID:31514071
RGD:150530482
NCBI chrNW_004624913:1,139,165...1,195,477
Ensembl chrNW_004624913:1,139,165...1,195,230
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Azgp1
alpha-2-glycoprotein 1, zinc-binding
ISO
mRNA:decreased expression:liver associated with hepatocellular carcinoma;protein:decreased expression:liver: associated with hepatitis B;mRNA:decreased expression:liver
RGD
PMID:22625427 PMID:26902423
RGD:153350130 RGD:153350133
NCBI chrNW_004624740:17,054,221...17,062,420
Ensembl chrNW_004624740:17,054,221...17,063,226
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Azin1
antizyme inhibitor 1
ISO
associated with hepatocellular carcinoma;RNA:increased editing:liver associated with hepatitis B;DNA SNP: :rs2679757 (human)
RGD
PMID:21586232 PMID:23291631
RGD:14700702 RGD:14700705
NCBI chrNW_004624763:19,643,980...19,667,125
Ensembl chrNW_004624763:19,643,980...19,667,125
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Bambi
BMP and activin membrane bound inhibitor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30097701
NCBI chrNW_004624805:1,967,174...1,973,030
Ensembl chrNW_004624805:1,967,101...1,974,898
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Becn1
beclin 1
ISO
protein:increased expression:skeletal muscle
RGD
PMID:22895779
RGD:11561934
NCBI chrNW_004624795:1,386,154...1,406,314
Ensembl chrNW_004624795:1,385,756...1,405,714
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C1qb
complement C1q B chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624764:7,377,013...7,382,953
Ensembl chrNW_004624764:7,376,967...7,383,445
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Casp8
caspase 8
ISO
associated with cholestasis
RGD
PMID:29105510
RGD:13782297
NCBI chrNW_004624899:427,064...450,931
Ensembl chrNW_004624899:424,363...451,087
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Casp9
caspase 9
ISO
associated with cholestasis
RGD
PMID:29105510
RGD:13782297
NCBI chrNW_004624764:1,769,270...1,789,399
Ensembl chrNW_004624764:1,773,455...1,789,423
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Ccl5
C-C motif chemokine ligand 5
severity treatment
ISO
DNA:SNAP, haplotype: :rs11652536(human)
RGD
PMID:20978355 PMID:28011329
RGD:14995306 RGD:14995328
NCBI chrNW_004624875:3,334,136...3,342,085
Ensembl chrNW_004624875:3,334,078...3,341,614
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Ccn2
cellular communication network factor 2
ameliorates
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16652398 PMID:17657819 PMID:26396155 PMID:26946098 PMID:36469291
RGD:243048439 RGD:40925947
NCBI chrNW_004624753:6,022,033...6,024,866
Ensembl chrNW_004624753:6,023,069...6,024,833
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Ccnd2
cyclin D2
ISO
associated with hepatitis B;mRNA:decreased expression:Peripheral Blood Mononuclear Cell
RGD
PMID:33320844
RGD:151664743
NCBI chrNW_004624860:1,383,015...1,405,107
Ensembl chrNW_004624860:1,382,948...1,405,107
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Cd14
CD14 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20353583
NCBI chrNW_004624743:33,372,023...33,374,438
Ensembl chrNW_004624743:33,367,898...33,373,922
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Cd163
CD163 molecule
exacerbates
ISO
associated with Chronic Hepatitis B, Chronic Hepatitis C;protein:increased expression:blood plasma (human) protein:increased expression:blood serum (human)
RGD
PMID:24623375 PMID:26339412
RGD:11251207 RGD:127285681
NCBI chrNW_004624860:3,976,746...4,000,349
Ensembl chrNW_004624860:3,975,747...4,000,349
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Cd36
CD36 molecule (CD36 blood group)
ISO
associated with Hypertension, Portal
RGD
PMID:22648712
RGD:6893541
NCBI chrNW_004624739:29,341,620...29,441,232
Ensembl chrNW_004624739:29,407,568...29,441,333
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Cd9
CD9 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624860:3,027,126...3,055,974
Ensembl chrNW_004624860:3,027,029...3,056,798
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Cdh1
cadherin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32659284
NCBI chrNW_004624746:17,480,472...17,557,722
Ensembl chrNW_004624746:17,483,469...17,557,581
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Cenpc
centromere protein C
ISO
associated with Anticentromere antibody positivity
RGD
PMID:25220385
RGD:27372886
NCBI chrNW_004624761:1,422,857...1,498,726
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Chrm3
cholinergic receptor muscarinic 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20197374
NCBI chrNW_004624775:10,948,075...11,427,898
Ensembl chrNW_004624775:10,949,983...10,951,755
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Cldn1
claudin 1
severity
ISO
associated with hepatitis C, Chronic;mRNA,protein:increased expression:liver (human)
RGD
PMID:21620107
RGD:26884347
NCBI chrNW_004624730:66,885,674...66,902,345
Ensembl chrNW_004624730:66,885,319...66,903,079
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Cnr1
cannabinoid receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11433348 PMID:21863215
NCBI chrNW_004624799:6,100,709...6,126,530
Ensembl chrNW_004624799:6,101,728...6,126,520
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Cnr2
cannabinoid receptor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15765409
NCBI chrNW_004624764:8,388,375...8,422,961
Ensembl chrNW_004624764:8,389,444...8,390,538
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Col1a1
collagen type I alpha 1 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21863215 PMID:24239723 PMID:24321339 PMID:26396155 PMID:32659284
NCBI chrNW_004624795:6,167,504...6,183,208
Ensembl chrNW_004624795:6,168,797...6,183,071
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Col1a2
collagen type I alpha 2 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624813:1,174,071...1,209,929
Ensembl chrNW_004624813:1,174,224...1,209,616
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Col3a1
collagen type III alpha 1 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:1880254 PMID:2566230 PMID:11167689 PMID:15787813 PMID:16679477
NCBI chrNW_004624899:1,192,078...1,230,528
Ensembl chrNW_004624899:1,192,360...1,230,404
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Col5a2
collagen type V alpha 2 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624899:1,035,797...1,175,394
Ensembl chrNW_004624899:1,035,964...1,174,844
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Commd1
copper metabolism domain containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17919502
NCBI chrNW_004624762:11,302,730...11,407,074
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Cp
ceruloplasmin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513 PMID:26396155
NCBI chrNW_004624730:26,458,554...26,510,796
Ensembl chrNW_004624730:26,462,550...26,511,078
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Cpeb1
cytoplasmic polyadenylation element binding protein 1
ISO
associated with Hepatitis C, Chronic; protein:increased expression:liver
RGD
PMID:26627607
RGD:11528851
NCBI chrNW_004624768:18,386,415...18,468,879
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Cpeb4
cytoplasmic polyadenylation element binding protein 4
ISO
associated with Hepatitis C, Chronic; protein:increased expression:liver
RGD
PMID:26627607
RGD:11528851
NCBI chrNW_004624733:16,082,461...16,146,798
Ensembl chrNW_004624733:16,082,369...16,147,075
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Crp
C-reactive protein
ISO
associated with Hepatitis C, Chronic;protein:decreased expression:serum
RGD
PMID:21806828
RGD:9491781
NCBI chrNW_004624794:1,531,555...1,533,804
Ensembl chrNW_004624794:1,531,571...1,533,804
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Csf1r
colony stimulating factor 1 receptor
exacerbates
ISO
associated with hepatitis C, liver cirrhosis;protein:increased expression:serum (human)
RGD
PMID:26437001
RGD:11079330
NCBI chrNW_004624774:9,363,156...9,391,939
Ensembl chrNW_004624774:9,363,908...9,391,986
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Ctnnb1
catenin beta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21047994
NCBI chrNW_004624730:77,876,361...77,887,228
Ensembl chrNW_004624730:77,875,257...77,887,234
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Cxcl10
C-X-C motif chemokine ligand 10
severity disease_progression
ISO
mRNA:increased expression:liver associated with Chronic Hepatitis B;
RGD
PMID:11418676 PMID:28067328 PMID:29105936
RGD:27095892 RGD:27095953 RGD:27095955
NCBI chrNW_004624757:14,989,241...14,991,650
Ensembl chrNW_004624757:14,989,084...14,991,910
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Cxcl14
C-X-C motif chemokine ligand 14
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33069761
NCBI chrNW_004624733:11,455,166...11,463,086
Ensembl chrNW_004624733:11,455,047...11,463,176
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Cxcl8
C-X-C motif chemokine ligand 8
disease_progression
ISO
CTD Direct Evidence: therapeutic mRNA, protein:increased expression:liver, serum (human)
CTD RGD
PMID:15763341 PMID:21731723
RGD:26884357
NCBI chrNW_004624730:1,744,097...1,747,206
Ensembl chrNW_004624730:1,743,916...1,747,293
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Cygb
cytoglobin
ISO
RGD
PMID:11320098 PMID:16581302
RGD:68672 RGD:9685176
NCBI chrNW_004624801:6,385,771...6,395,705
Ensembl chrNW_004624801:6,384,213...6,395,979
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Dgat1
diacylglycerol O-acyltransferase 1
treatment
ISO
associated with Non-alcoholic Fatty Liver Disease;
RGD
PMID:18000880
RGD:10400849
NCBI chrNW_004624735:12,525,120...12,535,436
Ensembl chrNW_004624735:12,525,284...12,535,193
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Dhcr7
7-dehydrocholesterol reductase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24381012
NCBI chrNW_004624767:16,118,157...16,132,225
Ensembl chrNW_004624767:16,118,052...16,132,834
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Dnmt1
DNA methyltransferase 1
ISO
mRNA,protein:increased expression:liver:
RGD
PMID:24211420
RGD:9588224
NCBI chrNW_004624828:2,316,042...2,358,866
Ensembl chrNW_004624828:2,315,251...2,358,711
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Drd4
dopamine receptor D4
disease_progression
ISO
DNA:repeats:exon:
RGD
PMID:23298155
RGD:401959737
NCBI chrNW_004624766:21,834,093...21,837,314
Ensembl chrNW_004624766:21,834,169...21,836,710
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Edn1
endothelin 1
ISO
mRNA:increased expression:liver (rat)
RGD
PMID:20628429
RGD:4144843
NCBI chrNW_004624756:13,842,482...13,849,003
Ensembl chrNW_004624756:13,842,164...13,849,029
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Egfr
epidermal growth factor receptor
severity
ISO
associated with non-alcoholic fatty liver disease;protein:increased expression:plasma
RGD
PMID:28650518
RGD:14401722
NCBI chrNW_004624740:584,133...713,205
Ensembl chrNW_004624740:589,606...713,271
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Egr1
early growth response 1
ISO
protein:increased expression:liver, nucleus
RGD
PMID:22292946
RGD:10395298
NCBI chrNW_004624743:31,247,855...31,251,675
Ensembl chrNW_004624743:31,247,516...31,252,205
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Eln
elastin
severity
ISO
protein:increased expression:liver:
RGD
PMID:22223197
RGD:9585666
NCBI chrNW_004624740:13,856,932...13,886,266
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Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
ISO
associated with hepatitis C
RGD
PMID:15651265
RGD:9685530
NCBI chrNW_004624760:859,598...865,194
Ensembl chrNW_004624760:859,637...866,804
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Ephb2
EPH receptor B2
ameliorates
ISO
associated with malaria;
RGD
PMID:25784101
RGD:127285023
NCBI chrNW_004624764:7,421,818...7,599,800
Ensembl chrNW_004624764:7,421,862...7,593,482
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F2
coagulation factor II, thrombin
severity
ISO
protein:decreased expression:plasma (human) CTD Direct Evidence: marker/mechanism protein:decreased activity:plasma (human) protein:increased expression:plasma (human)
RGD CTD
PMID:9863491 PMID:10216089 PMID:15726661 PMID:29768734
RGD:14401592 RGD:14985235 RGD:14985236
NCBI chrNW_004624767:1,876,974...1,887,720
Ensembl chrNW_004624767:1,877,024...1,887,958
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F2r
coagulation factor II thrombin receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21037076
NCBI chrNW_004624869:1,181,288...1,200,751
Ensembl chrNW_004624869:1,181,354...1,200,664
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F3
coagulation factor III, tissue factor
treatment severity
ISO
CTD Direct Evidence: marker/mechanism mRNA, protein:increased expression, increased activity:monocyte (human)
CTD RGD
PMID:9863491 PMID:10216089 PMID:15946135 PMID:21037076 PMID:28883694
RGD:11341737 RGD:14401577 RGD:14401592 RGD:14401724
NCBI chrNW_004624742:3,112,827...3,123,424
Ensembl chrNW_004624742:3,112,801...3,124,301
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F5
coagulation factor V
disease_progression susceptibility
ISO
CTD Direct Evidence: marker/mechanism associated with liver fibrosis, Factor V Leiden;DNA:missense mutation:cds:rs6025 (human)
CTD RGD
PMID:10520855 PMID:18485088 PMID:26226452
RGD:14700659 RGD:14700663
NCBI chrNW_004624826:7,438,632...7,507,322
Ensembl chrNW_004624826:7,438,682...7,507,012
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Fah
fumarylacetoacetate hydrolase
ISO
RGD
PMID:27510266
RGD:14398823
NCBI chrNW_004624941:1,039,389...1,056,568
Ensembl chrNW_004624941:1,039,429...1,056,568
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Farsb
phenylalanyl-tRNA synthetase subunit beta
ISO
ClinVar Annotator: match by term: Liver cirrhosis
ClinVar
PMID:29979980
NCBI chrNW_004624823:2,559,757...2,627,606
Ensembl chrNW_004624823:2,559,756...2,627,606
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Fbn1
fibrillin 1
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:14661032 PMID:26396155
RGD:12910489
NCBI chrNW_004624731:11,086,240...11,318,111
Ensembl chrNW_004624731:11,086,844...11,318,102
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Fgf19
fibroblast growth factor 19
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28673684
NCBI chrNW_004624767:17,434,501...17,439,351
Ensembl chrNW_004624767:17,432,358...17,438,173
G
Fgf2
fibroblast growth factor 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17093919
NCBI chrNW_004624777:3,268,674...3,321,424
Ensembl chrNW_004624777:3,268,953...3,321,145
G
Fgf7
fibroblast growth factor 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17692400
NCBI chrNW_004624731:10,413,715...10,468,660
Ensembl chrNW_004624731:10,413,645...10,468,690
G
Fgfr2
fibroblast growth factor receptor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17692400
NCBI chrNW_004624737:25,052,698...25,158,346
Ensembl chrNW_004624737:25,052,606...25,158,529
G
Fgfr4
fibroblast growth factor receptor 4
ISO
associated with hepatocellular carcinoma; DNA:SNP:cds: p.G388R (rs351855) (human)
RGD
PMID:25860955
RGD:11057080
NCBI chrNW_004624733:12,964,893...12,979,198
Ensembl chrNW_004624733:12,964,746...12,976,732
G
Flt1
fms related receptor tyrosine kinase 1
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expressin:liver:
CTD RGD
PMID:11981751
RGD:634296
NCBI chrNW_004624776:10,043,113...10,218,598
Ensembl chrNW_004624776:10,043,258...10,219,104
G
Focad
focadhesin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:35864190
NCBI chrNW_004624736:24,635,453...24,999,908
Ensembl chrNW_004624736:24,675,545...24,999,585
G
Foxo3
forkhead box O3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33372984
NCBI chrNW_004624780:13,621,733...13,740,399
Ensembl chrNW_004624780:13,622,948...13,740,374
G
Fubp1
far upstream element binding protein 1
ISO
associated with Chronic Hepatitis C;mRNA:increased expression:liver (human)
RGD
PMID:25995247
RGD:151361196
NCBI chrNW_004624742:19,279,544...19,313,139
G
Gc
GC vitamin D binding protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24381012
NCBI chrNW_004624890:3,274,239...3,318,281
Ensembl chrNW_004624890:3,226,900...3,318,316
G
Gch1
GTP cyclohydrolase 1
ISO
mRNA, protein:decreased expression:liver
RGD
PMID:16799985
RGD:329970289
NCBI chrNW_004624731:14,459,164...14,502,485
Ensembl chrNW_004624731:14,459,303...14,500,429
G
Gclc
glutamate-cysteine ligase catalytic subunit
ISO
RGD
PMID:22942279
RGD:11049542
NCBI chrNW_004624850:749,046...793,654
Ensembl chrNW_004624850:749,050...793,959
G
Gdf1
growth differentiation factor 1
disease_progression
ISO
associated with Stable Angina; protein:decreased expression:blood plasma (human)
RGD
PMID:36268984
RGD:243065147
NCBI chrNW_004624908:1,935,525...1,937,012
Ensembl chrNW_004624908:1,935,539...1,936,953
G
Ggt1
gamma-glutamyltransferase 1
disease_progression severity
ISO
associated with Hepatitis B, Chronic;
RGD
PMID:15997630 PMID:25254524 PMID:27793641
RGD:14701041 RGD:14747030 RGD:14747031
NCBI chrNW_004624747:10,030,034...10,048,554
G
Gli3
GLI family zinc finger 3
ISO
mRNA:increased expression:serum:
RGD
PMID:32319630
RGD:155791681
NCBI chrNW_004624740:18,961,395...19,238,760
Ensembl chrNW_004624740:18,975,596...19,235,900
G
Glul
glutamate-ammonia ligase
severity
ISO
associated with congestive heart failure
RGD
PMID:30950843
RGD:401793761
NCBI chrNW_004624771:2,608,779...2,618,130
G
Golm1
golgi membrane protein 1
ISO
protein:increased expression:serum
RGD
PMID:21140449
RGD:401827118
NCBI chrNW_004624809:9,485,832...9,555,889
Ensembl chrNW_004624809:9,486,724...9,534,333
G
Gp1ba
glycoprotein Ib platelet subunit alpha
treatment
ISO
RGD
PMID:31851564
RGD:42722628
NCBI chrNW_004624786:8,789,496...8,794,897
G
Gpc3
glypican 3
ISO
protein:increased expression:blood serum (human)
RGD
PMID:28801286
RGD:243065135
NCBI chrNW_004624797:13,234,741...13,678,542
Ensembl chrNW_004624797:13,230,932...13,678,742
G
Gpt
glutamic--pyruvic transaminase
severity
ISO
associated with Hepatitis B, Chronic;
RGD
PMID:30665287
RGD:14975252
NCBI chrNW_004624735:12,355,476...12,359,910
Ensembl chrNW_004624735:12,355,476...12,360,028
G
Grk2
G protein-coupled receptor kinase 2
ISO
associated with hepatitis B;protein:increased expression:mesenteric artery (human) protein:increased expression:hepatic artery
RGD
PMID:17256744 PMID:23742775
RGD:13792718 RGD:1625784
NCBI chrNW_004624767:19,212,218...19,231,218
Ensembl chrNW_004624767:19,210,965...19,231,082
G
Hdac2
histone deacetylase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27396813
NCBI chrNW_004624856:4,834,197...4,861,546
Ensembl chrNW_004624856:4,834,217...4,861,592
G
Hfe
homeostatic iron regulator
ISO
DNA:missense mutations: :p.H63D, p.C282Y (human)
RGD
PMID:27816425
RGD:14701047
NCBI chrNW_004624756:821,738...831,482
Ensembl chrNW_004624756:823,947...831,376
G
Hgf
hepatocyte growth factor
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17097021
NCBI chrNW_004624739:30,233,589...30,307,508
Ensembl chrNW_004624739:30,236,146...30,307,356
G
Hhip
hedgehog interacting protein
ISO
mRNA:decreased expression:liver:
RGD
PMID:19815628
RGD:11552602
NCBI chrNW_004624853:3,649,974...3,739,344
Ensembl chrNW_004624853:3,649,967...3,735,834
G
Hif1a
hypoxia inducible factor 1 subunit alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:36126797
NCBI chrNW_004624734:39,414,458...39,471,705
Ensembl chrNW_004624734:39,411,824...39,471,705
G
Hnf4a
hepatocyte nuclear factor 4 alpha
ISO
protein:decreased expression:liver:
RGD
PMID:20876809
RGD:12904747
NCBI chrNW_004624790:10,039,344...10,065,167
Ensembl chrNW_004624790:10,038,999...10,100,649
G
Hras
HRas proto-oncogene, GTPase
ISO
mRNA:increased expression:liver (human)
RGD
PMID:7535324
RGD:14694815
NCBI chrNW_004624766:21,907,423...21,913,414
Ensembl chrNW_004624766:21,911,241...21,913,653
G
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15199296
NCBI chrNW_004624746:18,883,587...18,889,205
Ensembl chrNW_004624746:18,883,353...18,889,402
G
Icam1
intercellular adhesion molecule 1
susceptibility
ISO
associated with Hepatitis B, Chronic;DNA:missense mutations, haplotype:cds:p.G241R, p.K469E (human) associated with chronic intermittent hypoxia; mRNA, protein:increased expression:liver (rat)
RGD
PMID:18233990 PMID:32626927
RGD:14402042 RGD:401959337
NCBI chrNW_004624828:2,432,584...2,451,997
Ensembl chrNW_004624828:2,432,550...2,453,071
G
Ido2
indoleamine 2,3-dioxygenase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32289347
NCBI chrNW_004624780:3,620,899...3,668,351
Ensembl chrNW_004624780:3,621,623...3,668,177
G
Ifng
interferon gamma
ISO
RGD
PMID:12389079 PMID:21664391
RGD:10755749 RGD:6893452
NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534
G
Igf1r
insulin like growth factor 1 receptor
susceptibility
ISO
associated with Hepatis B virus;DNA:SNP:3'UTR:rs3743251(human)
RGD
PMID:24758241
RGD:14985227
NCBI chrNW_004624768:5,396,027...5,688,435
Ensembl chrNW_004624768:5,396,156...5,681,809
G
Igf2
insulin like growth factor 2
severity
ISO
associated with non-alcoholic fatty liver disease;protein:decreased expression:plasma
RGD
PMID:28650518
RGD:14401722
NCBI chrNW_004624767:14,969,977...14,997,577
Ensembl chrNW_004624767:14,969,866...14,979,026
G
Igfbp1
insulin like growth factor binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624740:6,893,334...6,897,591
Ensembl chrNW_004624740:6,893,867...6,897,377
G
Igfbp2
insulin like growth factor binding protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624823:8,460,968...8,486,495
Ensembl chrNW_004624823:8,460,553...8,486,495
G
Il10
interleukin 10
severity no_association
ISO
associated with Hepatitis C, Chronic;DNA:SNP:promoter:-592C>A (human) DNA:SNP:promoter:-1082G>A (rs1800896) (human) associated with Hepatitis C, Chronic;DNA:SNP:promoter:-1082 G>A (human) DNA:SNP:promoter:-592C>A (rs1800872) (human)
RGD
PMID:26909998 PMID:27660094
RGD:14975134 RGD:14975152
NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732
G
Il18
interleukin 18
severity
ISO
associated with Hepatitis C, Chronic;mRNA:increased expression:PBMC: protein:increased expression:plasma:
RGD
PMID:12462332 PMID:19740312
RGD:14695542 RGD:14696656
NCBI chrNW_004624784:7,294,286...7,312,959
Ensembl chrNW_004624784:7,294,183...7,304,687
G
Il18bp
interleukin 18 binding protein
disease_progression
ISO
protein:increased expression:plasma:
RGD
PMID:12462332
RGD:14695542
NCBI chrNW_004624817:4,963,586...4,967,122
Ensembl chrNW_004624817:4,964,403...4,965,944
G
Il1b
interleukin 1 beta
ISO
associated with chronic intermittent hypoxia; mRNA, protein:increased expression:liver (rat)
RGD
PMID:32626927
RGD:401959337
NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760
G
Il1rl1
interleukin 1 receptor like 1
severity
ISO
associated with Schistosomiasis Japonica
RGD
PMID:31200771
RGD:39938956
NCBI chrNW_004624749:6,795,822...6,873,068
Ensembl chrNW_004624749:6,795,748...6,873,701
G
Il2
interleukin 2
treatment
ISO
associated with sclerosing cholangitis
RGD
PMID:29698570
RGD:14928214
NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453
G
Il21
interleukin 21
exacerbates
ISO
associated with Chronic Hepatitis B;mRNA:increased expression: liver (human)
RGD
PMID:24611989
RGD:127285546
NCBI chrNW_004624777:3,054,368...3,061,304
Ensembl chrNW_004624777:3,054,368...3,061,304
G
Il27
interleukin 27
ISO
associated with hepatitis B;protein:increased expression:blood serum (human)
RGD
PMID:22230324
RGD:126790507
NCBI chrNW_004624782:13,009,450...13,015,548
Ensembl chrNW_004624782:13,009,564...13,015,440
G
Il33
interleukin 33
severity
ISO
associated with Schistosomiasis Japonica
RGD
PMID:31053540 PMID:31200771
RGD:39938956 RGD:40400690
NCBI chrNW_004624736:10,733,944...10,786,188
Ensembl chrNW_004624736:10,764,486...10,784,864
G
Il6
interleukin 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12830005
NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318
G
Irf5
interferon regulatory factor 5
severity
ISO
RGD
PMID:27942586
RGD:40924562
NCBI chrNW_004624783:7,267,680...7,275,918
Ensembl chrNW_004624783:7,260,005...7,274,433
G
Itgb6
integrin subunit beta 6
disease_progression
ISO
associated with Hepatitis C, Chronic;mRNA:increased expression:liver
RGD
PMID:18221819
RGD:2302245
NCBI chrNW_004624732:5,348,589...5,499,826
Ensembl chrNW_004624732:5,403,956...5,499,855
G
Itih4
inter-alpha-trypsin inhibitor heavy chain 4
ISO
associated with hepatitis B;protein:increased expression:serum
RGD
PMID:24836184
RGD:40903002
NCBI chrNW_004624822:4,397,704...4,411,562
Ensembl chrNW_004624822:4,397,744...4,411,406
G
Jak1
Janus kinase 1
treatment
ISO
associated with Schistosomiasis Japonica
RGD
PMID:27439782
RGD:19165137
NCBI chrNW_004624742:29,631,391...29,723,981
Ensembl chrNW_004624742:29,689,965...29,723,981
G
Jak2
Janus kinase 2
severity
ISO
mRNA:increased expression:liver (human)
RGD
PMID:26385087
RGD:18337263
NCBI chrNW_004624736:9,724,876...9,827,364
Ensembl chrNW_004624736:9,724,369...9,830,365
G
Jund
JunD proto-oncogene, AP-1 transcription factor subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17133482
NCBI chrNW_004624908:1,572,628...1,574,205
Ensembl chrNW_004624908:1,573,174...1,574,113
G
Kdr
kinase insert domain receptor
disease_progression
ISO
associated with Chronic Hepatitis
RGD
PMID:27323788
RGD:126908000
NCBI chrNW_004624761:14,330,224...14,380,680
Ensembl chrNW_004624761:14,330,489...14,379,051
G
Klf5
KLF transcription factor 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:33549628
NCBI chrNW_004624751:27,488,434...27,509,871
Ensembl chrNW_004624751:27,489,535...27,505,494
G
Klkb1
kallikrein B1
ISO
RGD
PMID:14986822
RGD:7297050
NCBI chrNW_004624769:17,066,055...17,088,587
Ensembl chrNW_004624769:17,067,342...17,087,408
G
Krt18
keratin 18
severity
ISO
protein:H127L CTD Direct Evidence: therapeutic protein:increased expression: serum (human)
RGD CTD
PMID:9011570 PMID:20538000 PMID:29023872
RGD:1624318 RGD:18337484
NCBI chrNW_004624904:1,011,675...1,015,319
Ensembl chrNW_004624904:1,011,755...1,015,416
G
Krt8
keratin 8
ISO
protein:increased phosphorylation:liver (human) CTD Direct Evidence: therapeutic
RGD CTD
PMID:11372009 PMID:15368451 PMID:20538000
RGD:14401583 RGD:1600062
NCBI chrNW_004624904:970,136...978,211
G
Lamc2
laminin subunit gamma 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624814:10,475,629...10,536,694
Ensembl chrNW_004624814:10,476,323...10,536,724
G
Lbp
lipopolysaccharide binding protein
ISO
protein:increased expression:liver
RGD
PMID:17918268
RGD:2292126
NCBI chrNW_004624842:1,306,299...1,332,269
Ensembl chrNW_004624842:1,301,831...1,332,346
G
Ldlr
low density lipoprotein receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:36108984
NCBI chrNW_004624828:2,999,122...3,021,893
Ensembl chrNW_004624828:2,999,169...3,021,987
G
Lgals1
galectin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624752:10,220,115...10,223,434
Ensembl chrNW_004624752:10,219,872...10,223,317
G
Lgals3
galectin 3
ISO
RGD
PMID:16549783
RGD:9685224
NCBI chrNW_004624731:14,300,138...14,307,843
Ensembl chrNW_004624731:14,298,201...14,304,637
G
Lgals3bp
galectin 3 binding protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624801:8,302,447...8,311,836
Ensembl chrNW_004624801:8,302,210...8,311,904
G
LOC101698463
HLA class II histocompatibility antigen, DP alpha 1 chain
severity
ISO
DAN:polymorphism: :
RGD
PMID:10203020
RGD:14694972
NCBI chrNW_004624754:23,674,935...23,683,044
Ensembl chrNW_004624754:23,674,448...23,683,662
G
LOC101700018
sterol 26-hydroxylase, mitochondrial
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24381012
NCBI chrNW_004624823:6,199,807...6,258,273
Ensembl chrNW_004624823:6,200,047...6,258,001
G
LOC101703821
HLA class II histocompatibility antigen, DQ beta 1 chain
susceptibility
ISO
associated with Schistosomiasis Japonica;DNA:polymorphisms: :HLA-DQB1*0303, HLA-DQB1*0601, HLA-DQB1*0609(human)
RGD
PMID:11336748
RGD:36049755
NCBI chrNW_004624754:23,895,509...23,902,487
Ensembl chrNW_004624754:23,895,607...23,906,713
G
LOC101717043
cytochrome b-245 light chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chrNW_004624746:911,852...919,361
Ensembl chrNW_004624746:911,842...919,362
G
LOC101724787
vitamin D 25-hydroxylase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24381012
NCBI chrNW_004624766:6,667,662...6,678,045
Ensembl chrNW_004624766:6,667,234...6,677,992
G
LOC101724812
C-C chemokine receptor type 1
ISO
associated with Fatty Liver
RGD
PMID:19280268
RGD:5688143
NCBI chrNW_004624730:74,822,848...74,828,614
Ensembl chrNW_004624730:74,826,659...74,827,726
G
Lox
lysyl oxidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624774:20,116,625...20,137,767
Ensembl chrNW_004624774:20,116,970...20,134,355
G
Loxl1
lysyl oxidase like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30097701
NCBI chrNW_004624781:518,703...537,657
Ensembl chrNW_004624781:520,143...537,727
G
Lum
lumican
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624750:15,553,400...15,560,746
Ensembl chrNW_004624750:15,553,383...15,559,408
G
Map1lc3a
microtubule associated protein 1 light chain 3 alpha
ISO
protein:increased expression:skeletal muscle
RGD
PMID:22895779
RGD:11561934
NCBI chrNW_004624842:4,800,533...4,802,235
Ensembl chrNW_004624842:4,800,539...4,802,094
G
Mapk14
mitogen-activated protein kinase 14
exacerbates
ISO
RGD
PMID:23271722
RGD:151665348
NCBI chrNW_004624754:21,528,121...21,598,064
Ensembl chrNW_004624754:21,527,333...21,597,733
G
Mbl2
mannose binding lectin 2
susceptibility severity
ISO
associated with hepatitis B;DNA:SNP:exon: associated with hepatitis C; DNA:haplotype:promoter, exon:
RGD
PMID:20570631 PMID:26857650
RGD:14696832 RGD:14696836
NCBI chrNW_004624791:10,881,319...10,886,294
Ensembl chrNW_004624791:10,881,268...10,886,297
G
Mgll
monoglyceride lipase
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:30301768
NCBI chrNW_004624974:85,513...169,904
Ensembl chrNW_004624974:87,600...170,228
G
Mical2
microtubule associated monooxygenase, calponin and LIM domain containing 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32659284
NCBI chrNW_004624766:4,167,480...4,300,528
Ensembl chrNW_004624766:4,167,433...4,300,641
G
Mmp1
matrix metallopeptidase 1
severity
ISO
protein:decreased expression:serum (rat)
RGD
PMID:14606082 PMID:16124044
RGD:7207132 RGD:7207396
NCBI chrNW_004624878:71,642...79,660
Ensembl chrNW_004624878:71,642...79,602
G
Mmp13
matrix metallopeptidase 13
ISO
RGD
PMID:21382168
RGD:7207361
NCBI chrNW_004624918:2,228,688...2,239,852
G
Mmp2
matrix metallopeptidase 2
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15763341 PMID:23411180 PMID:26396155
RGD:8657103
NCBI chrNW_004624757:1,450,680...1,479,160
Ensembl chrNW_004624757:1,448,698...1,479,255
G
Mpo
myeloperoxidase
disease_progression
ISO
DNA:SNP:promoter:-463G>A( rs2333227)(human)
RGD
PMID:19731237
RGD:26923907
NCBI chrNW_004624871:121,026...131,433
Ensembl chrNW_004624871:121,026...131,323
G
Mrtfa
myocardin related transcription factor A
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:33779332
NCBI chrNW_004624752:7,836,545...8,050,176
Ensembl chrNW_004624752:7,878,876...8,050,274
G
Mthfr
methylenetetrahydrofolate reductase
susceptibility
ISO
DNA:SNP: :677C>T(human)
RGD
PMID:25987440
RGD:14696749
NCBI chrNW_004624818:1,184,736...1,202,708
Ensembl chrNW_004624818:1,187,869...1,199,168
G
Muc2
mucin 2, oligomeric mucus/gel-forming
ISO
mRNA:increased expression:ileum
RGD
PMID:22172882
RGD:7349362
NCBI chrNW_004624766:21,493,125...21,522,535
G
Myc
MYC proto-oncogene, bHLH transcription factor
ISO
mRNA,protein:increased expression:liver
RGD
PMID:23770341
RGD:14695015
NCBI chrNW_004624735:27,780,338...27,784,714
Ensembl chrNW_004624735:27,780,037...27,784,806
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Nfe2l2
NFE2 like bZIP transcription factor 2
treatment
ISO
CTD Direct Evidence: therapeutic
RGD CTD
PMID:22732220 PMID:23793039
RGD:10412731
NCBI chrNW_004624787:14,355,330...14,381,353
Ensembl chrNW_004624787:14,355,791...14,381,251
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Nos3
nitric oxide synthase 3
treatment
ISO
protein:decreased activity:liver (rat)
RGD
PMID:10535886 PMID:12759254
RGD:7775034 RGD:7794774
NCBI chrNW_004624800:5,600,215...5,619,020
Ensembl chrNW_004624800:5,600,212...5,619,004
G
Npc1
NPC intracellular cholesterol transporter 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22216111
NCBI chrNW_004624770:8,592,473...8,642,063
Ensembl chrNW_004624770:8,592,457...8,641,843
G
Nppa
natriuretic peptide A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15613622
NCBI chrNW_004624818:1,147,654...1,149,722
Ensembl chrNW_004624818:1,147,974...1,148,927
G
Nppb
natriuretic peptide B
severity
ISO
protein:increased expression:plasma protein:increased expression:plasma:
RGD
PMID:9350073 PMID:23940514
RGD:7246914 RGD:7248670
NCBI chrNW_004624818:1,139,776...1,141,010
G
Nqo1
NAD(P)H quinone dehydrogenase 1
treatment
ISO
RGD
PMID:29078262
RGD:13442479
NCBI chrNW_004624746:16,684,620...16,698,194
Ensembl chrNW_004624746:16,684,407...16,697,479
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Nr1h4
nuclear receptor subfamily 1 group H member 4
treatment severity
ISO
mRNA:altered expression:liver, kidney (rat) mRNA:altered expression:liver (mouse)
RGD
PMID:19418582 PMID:30308196
RGD:15042865 RGD:15042868
NCBI chrNW_004624750:7,222,306...7,303,809
Ensembl chrNW_004624750:7,219,251...7,303,834
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P2rx7
purinergic receptor P2X 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32721574
NCBI chrNW_004624747:21,725,813...21,768,123
Ensembl chrNW_004624747:21,725,395...21,759,453
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Parp1
poly(ADP-ribose) polymerase 1
ISO
associated with Hepatitis B;mRNA:decreased expression:blood, mononuclear cell
RGD
PMID:25755481
RGD:11073733
NCBI chrNW_004624807:446,662...478,571
Ensembl chrNW_004624807:446,647...479,069
G
Pcolce
procollagen C-endopeptidase enhancer
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624740:16,476,004...16,480,818
Ensembl chrNW_004624740:16,475,058...16,480,807
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Pdcd10
programmed cell death 10
ISO
protein:increased expression:liver (human)
RGD
PMID:32186778
RGD:401827111
NCBI chrNW_004624730:45,653,470...45,698,461
Ensembl chrNW_004624730:45,654,022...45,678,745
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Pdgfa
platelet derived growth factor subunit A
ISO
ClinVar Annotator: match by term: Hepatic fibrosis
ClinVar
PMID:25741868
NCBI chrNW_004624740:26,172,808...26,191,557
Ensembl chrNW_004624740:26,169,064...26,188,866
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Pdgfb
platelet derived growth factor subunit B
ISO
mRNA: increased expression
RGD
PMID:22407906 PMID:22539040
RGD:6482830 RGD:6482858
NCBI chrNW_004624752:9,072,471...9,088,289
Ensembl chrNW_004624752:9,072,512...9,088,593
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Pdgfd
platelet derived growth factor D
ISO
mRNA,protein:increased expression:liver:
RGD
PMID:17397961
RGD:9854631
NCBI chrNW_004624918:1,052,640...1,293,138
Ensembl chrNW_004624918:1,052,567...1,293,192
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Pdia3
protein disulfide isomerase family A member 3
severity
ISO
protein:decreased expression:liver:
RGD
PMID:24562544
RGD:9999176
NCBI chrNW_004624804:10,754,978...10,784,641
Ensembl chrNW_004624804:10,755,103...10,784,337
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Pecam1
platelet and endothelial cell adhesion molecule 1
ISO
protein:increased expression:blood microparticle (human)
RGD
PMID:22465620
RGD:6771231
NCBI chrNW_004624870:33,293...122,536
G
Pemt
phosphatidylethanolamine N-methyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29416063
NCBI chrNW_004624849:3,818,115...3,907,250
Ensembl chrNW_004624849:3,817,915...3,908,888
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Pgf
placental growth factor
ISO
mRNA, protein:increased expression:liver, serum
RGD
PMID:21520176
RGD:6483607
NCBI chrNW_004624734:26,751,986...26,764,154
Ensembl chrNW_004624734:26,751,530...26,764,242
G
Phkg2
phosphorylase kinase catalytic subunit gamma 2
ISO
DNA:missense mutation, nonsense mutation (human)
RGD
PMID:9384616
RGD:737725
NCBI chrNW_004624782:13,864,002...13,880,568
Ensembl chrNW_004624782:13,871,130...13,881,001
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Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
treatment
ISO
associated with Schistosomiasis Japonica
RGD
PMID:29323718
RGD:38599216
NCBI chrNW_004624739:22,737,376...22,772,696
Ensembl chrNW_004624739:22,737,270...22,772,589
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Pkhd1
PKHD1 ciliary IPT domain containing fibrocystin/polyductin
ISO
DNA:deletion:exon:
RGD
PMID:17519956
RGD:14700917
NCBI chrNW_004624855:4,019,088...4,539,289
Ensembl chrNW_004624855:4,019,056...4,536,324
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Plau
plasminogen activator, urokinase
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:18481824 PMID:26396155
NCBI chrNW_004624754:7,405,637...7,415,870
Ensembl chrNW_004624754:7,408,983...7,416,559
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Plaur
plasminogen activator, urokinase receptor
disease_progression
ISO
protein:increased expression:serum
RGD
PMID:22098627
RGD:6484116
NCBI chrNW_004624907:1,174,648...1,188,919
Ensembl chrNW_004624907:1,174,448...1,189,377
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Plod2
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624730:22,944,710...23,034,200
Ensembl chrNW_004624730:22,944,184...23,034,231
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Postn
periostin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32344006
NCBI chrNW_004624920:542,479...575,760
Ensembl chrNW_004624920:540,750...575,855
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Pten
phosphatase and tensin homolog
ISO
CTD Direct Evidence: marker/mechanism associated with schistosomiasis;protein, mRNA:decreased expression:liver (mouse)
CTD RGD
PMID:26023714 PMID:31907686
RGD:127285596
NCBI chrNW_004624791:13,975,235...14,056,900
G
Ptgs2
prostaglandin-endoperoxide synthase 2
severity
ISO
human gene in mouse model
RGD
PMID:29109031
RGD:14695008
NCBI chrNW_004624814:6,897,818...6,904,890
Ensembl chrNW_004624814:6,897,857...6,903,728
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Ptn
pleiotrophin
ISO
protein:increased expression:liver (rat)
RGD
PMID:18381592
RGD:9834946
NCBI chrNW_004624765:17,523,086...17,625,264
Ensembl chrNW_004624765:17,522,916...17,548,184
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Rad50
RAD50 double strand break repair protein
treatment
ISO
RGD
PMID:21893185
RGD:9831391
NCBI chrNW_004624733:39,445,083...39,544,415
Ensembl chrNW_004624733:39,447,461...39,544,409
G
Rbp4
retinol binding protein 4
severity
ISO
associated with lived disease; protein:decreased expression:blood serum (human)
RGD
PMID:17337499
RGD:329845879
NCBI chrNW_004624737:4,795,054...4,800,830
Ensembl chrNW_004624737:4,791,628...4,800,989
G
Rela
RELA proto-oncogene, NF-kB subunit
ISO
associated with chronic intermittent hypoxia; mRNA, protein:increased expression:liver (rat)
RGD
PMID:32626927
RGD:401959337
NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272
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Reln
reelin
ISO
protein:altered expression:plasma (human)
RGD
PMID:18449964
RGD:2317777
NCBI chrNW_004624739:25,472,626...25,918,064
Ensembl chrNW_004624739:25,472,561...25,918,167
G
Ren
renin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15613622
NCBI chrNW_004624807:6,817,472...6,827,374
Ensembl chrNW_004624807:6,817,195...6,827,462
G
Rgn
regucalcin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chrNW_004624887:3,881,624...3,900,144
Ensembl chrNW_004624887:3,883,213...3,899,277
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Rgs2
regulator of G protein signaling 2
ISO
RGD
PMID:19003918
RGD:10449440
NCBI chrNW_004624814:754,743...758,148
Ensembl chrNW_004624814:753,164...758,192
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Serpina6
serpin family A member 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chrNW_004624734:10,638,031...10,650,297
Ensembl chrNW_004624734:10,637,515...10,651,033
G
Serpine1
serpin family E member 1
susceptibility
ISO
DNA:polymorphism:promoter:
RGD
PMID:25987440
RGD:14696749
NCBI chrNW_004624740:16,128,145...16,136,696
Ensembl chrNW_004624740:16,128,059...16,137,337
G
Serping1
serpin family G member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624864:3,091,397...3,103,084
Ensembl chrNW_004624864:3,091,083...3,103,090
G
Serpinh1
serpin family H member 1
treatment disease_progression
ISO
associated with Schistosomiasis Japonica associated with schistosomiasis;mRNA:increased expression:liver (human) CTD Direct Evidence: marker/mechanism associated with Schistosomiasis Japonica;mRNA:increased expression:liver (human)
RGD CTD
PMID:24295791 PMID:24321339 PMID:25111595 PMID:31612672 PMID:32410640
RGD:41410780 RGD:41410784 RGD:41410785 RGD:41412161
NCBI chrNW_004624817:1,561,471...1,570,425
Ensembl chrNW_004624817:1,561,471...1,570,947
G
Shc1
SHC adaptor protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:32659284
NCBI chrNW_004624885:2,511,039...2,520,883
Ensembl chrNW_004624885:2,511,240...2,521,155
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Slc13a4
solute carrier family 13 member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chrNW_004624765:15,960,269...16,001,700
Ensembl chrNW_004624765:15,963,047...16,000,929
G
Slc17a2
solute carrier family 17 member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chrNW_004624756:1,088,919...1,119,361
Ensembl chrNW_004624756:1,088,943...1,106,509
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Slc22a8
solute carrier family 22 member 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chrNW_004624926:1,373,804...1,390,248
Ensembl chrNW_004624926:1,374,103...1,388,586
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Slc30a10
solute carrier family 30 member 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22926781
NCBI chrNW_004624835:3,598,375...3,612,165
Ensembl chrNW_004624835:3,598,260...3,611,307
G
Slc6a4
solute carrier family 6 member 4
susceptibility
ISO
associated with alcohol use disorder;DNA:deletion:promoter:-1212_-1255 (human)
RGD
PMID:11236836
RGD:36947396
NCBI chrNW_004624786:2,673,285...2,711,432
Ensembl chrNW_004624786:2,672,552...2,710,914
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Smad3
SMAD family member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21605584
NCBI chrNW_004624781:5,795,652...5,890,047
Ensembl chrNW_004624781:5,795,652...5,890,371
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Smad7
SMAD family member 7
ISO
associated with hepatocellular carcinoma; mRNA:increased expression:liver (human)
RGD
PMID:25602745
RGD:14401589
NCBI chrNW_004624778:12,415,364...12,444,882
Ensembl chrNW_004624778:12,415,282...12,444,835
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Smo
smoothened, frizzled class receptor
treatment
ISO
RGD
PMID:22994359
RGD:150521663
NCBI chrNW_004624783:7,012,385...7,039,302
Ensembl chrNW_004624783:7,011,899...7,039,921
G
Socs1
suppressor of cytokine signaling 1
exacerbates
ISO
associated with Chemical and Drug Induced Liver Injury;
RGD
PMID:30097285
RGD:150573810
NCBI chrNW_004624824:8,444,877...8,446,628
G
Sod2
superoxide dismutase 2
disease_progression
ISO
CTD Direct Evidence: marker/mechanism DNA:SNP:cds:p.Ala16Val(rs1799725)(human)
CTD RGD
PMID:19731237 PMID:32659284
RGD:26923907
NCBI chrNW_004624855:3,260,800...3,271,864
Ensembl chrNW_004624855:3,260,809...3,271,367
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Spag9
sperm associated antigen 9
ISO
associated with Human Viral Hepatitis
RGD
PMID:29344208
RGD:30296654
NCBI chrNW_004624795:6,748,513...6,863,201
Ensembl chrNW_004624795:6,745,537...6,863,173
G
Sparc
secreted protein acidic and cysteine rich
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23408952
NCBI chrNW_004624733:37,348,993...37,369,804
Ensembl chrNW_004624733:37,338,284...37,369,804
G
Spint1
serine peptidase inhibitor, Kunitz type 1
ISO
mRNA:increased expression:spleen:
RGD
PMID:15086199
RGD:10043112
NCBI chrNW_004624804:8,092,700...8,105,478
Ensembl chrNW_004624804:8,093,346...8,106,193
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Spp1
secreted phosphoprotein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16221502
NCBI chrNW_004624872:4,505,796...4,513,247
Ensembl chrNW_004624872:4,505,522...4,513,742
G
Stat1
signal transducer and activator of transcription 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17133483
NCBI chrNW_004624854:5,067,578...5,106,052
Ensembl chrNW_004624854:5,067,535...5,102,106
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Stat3
signal transducer and activator of transcription 3
ISO
RGD
PMID:22687286
RGD:6892914
NCBI chrNW_004624795:1,648,235...1,680,788
Ensembl chrNW_004624795:1,648,080...1,681,200
G
Tagln2
transgelin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chrNW_004624794:1,331,075...1,338,445
G
Tfpi
tissue factor pathway inhibitor
ISO
RGD
PMID:23841464
RGD:11060135
NCBI chrNW_004624899:2,401,861...2,473,762
Ensembl chrNW_004624899:2,406,282...2,473,883
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Tgfb1
transforming growth factor beta 1
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:21037076 PMID:30686515 PMID:35101388 PMID:36368619
RGD:14985228
NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605
G
Tgfb2
transforming growth factor beta 2
ISO
RGD
PMID:30686515
RGD:14985228
NCBI chrNW_004624835:2,363,059...2,436,536
Ensembl chrNW_004624835:2,363,139...2,437,643
G
Tgfbr1
transforming growth factor beta receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28560358
NCBI chrNW_004624825:1,773,158...1,899,120
Ensembl chrNW_004624825:1,839,178...1,899,156
G
Tgm2
transglutaminase 2
treatment severity
ISO
associated with Schistosomiasis Japonica
RGD
PMID:31200771
RGD:39938956
NCBI chrNW_004624842:1,491,583...1,522,293
Ensembl chrNW_004624842:1,491,584...1,522,287
G
Thbs1
thrombospondin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18407596
NCBI chrNW_004624804:6,849,660...6,866,164
Ensembl chrNW_004624804:6,849,670...6,867,684
G
Thpo
thrombopoietin
ISO
mRNA:decreased expression:liver
RGD
PMID:9794189
RGD:1580082
NCBI chrNW_004624730:72,210,880...72,218,615
Ensembl chrNW_004624730:72,212,423...72,219,485
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Tlr2
toll like receptor 2
ISO
RGD
PMID:24815695
RGD:15090811
NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833
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Tlr3
toll like receptor 3
susceptibility
ISO
DNA:snp: :rs3775290(human)
RGD
PMID:26024592
RGD:21079416
NCBI chrNW_004624769:16,925,969...16,945,250
Ensembl chrNW_004624769:16,925,984...16,941,196
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Tlr4
toll like receptor 4
treatment
ISO
protein:increased expression:intestine: associated with chronic intermittent hypoxia
RGD
PMID:20006396 PMID:26809353 PMID:27061671 PMID:32626927
RGD:14697732 RGD:14700654 RGD:18182934 RGD:401959337
NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120
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Tmem67
transmembrane protein 67
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19508969
NCBI chrNW_004624763:1,219,779...1,281,297
Ensembl chrNW_004624763:1,219,827...1,264,071
G
Tnf
tumor necrosis factor
severity
ISO
protein:increased expression:serum (human) associated with chronic intermittent hypoxia; mRNA, protein:increased expression:liver (rat)
RGD
PMID:19695831 PMID:32626927
RGD:14995448 RGD:401959337
NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531
G
Tnfrsf1b
TNF receptor superfamily member 1B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20353583
NCBI chrNW_004624818:894,470...922,806
Ensembl chrNW_004624818:896,150...922,710
G
Trpm7
transient receptor potential cation channel subfamily M member 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25150141
NCBI chrNW_004624731:9,490,885...9,588,255
Ensembl chrNW_004624731:9,491,157...9,588,346
G
Unc93b1
unc-93 homolog B1, TLR signaling regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513
NCBI chrNW_004624767:18,859,990...18,869,083
Ensembl chrNW_004624767:18,860,017...18,868,581
G
Vash1
vasohibin 1
treatment
ISO
associated with Hepatitis C, Chronic; protein:increased expression:liver
RGD
PMID:24390792
RGD:15003198
NCBI chrNW_004624734:25,034,266...25,053,409
Ensembl chrNW_004624734:25,034,266...25,053,398
G
Vcam1
vascular cell adhesion molecule 1
ISO
associated with chronic intermittent hypoxia; mRNA, protein:increased expression:liver (rat)
RGD
PMID:32626927
RGD:401959337
NCBI chrNW_004624857:3,606,573...3,625,991
Ensembl chrNW_004624857:3,606,431...3,627,063
G
Vdr
vitamin D receptor
severity
ISO
associated with nonalcoholic fatty liver disease; DNA:SNP: :rs1544410(human)
RGD
PMID:23622244 PMID:30218108 PMID:30683615
RGD:14401752 RGD:14402027 RGD:14402031
NCBI chrNW_004624816:4,314,146...4,423,946
Ensembl chrNW_004624816:4,365,961...4,424,514
G
Vegfa
vascular endothelial growth factor A
ISO
associated with Hepatitis C, Chronic; protein:increased expression:liver CTD Direct Evidence: marker/mechanism protein:increased expression:platelet:
RGD CTD
PMID:11981751 PMID:18544126 PMID:26627607
RGD:11528851 RGD:15003200
NCBI chrNW_004624754:15,929,414...15,943,637
G
Vegfc
vascular endothelial growth factor C
ISO
protein:increased expression:liver:
RGD
PMID:18544126
RGD:15003200
NCBI chrNW_004624769:7,689,812...7,817,366
Ensembl chrNW_004624769:7,689,407...7,817,450
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Vim
vimentin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25226513 PMID:26396155 PMID:32659284
NCBI chrNW_004624796:10,624,672...10,632,300
Ensembl chrNW_004624796:10,623,929...10,632,600
G
Vtn
vitronectin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26396155
NCBI chrNW_004624786:970,288...973,344
Ensembl chrNW_004624786:966,452...973,337
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Wdr35
WD repeat domain 35
ISO
mRNA:increased expression:liver (rat)
RGD
PMID:18472094
RGD:11553927
NCBI chrNW_004624738:2,618,464...2,720,567
Ensembl chrNW_004624738:2,618,738...2,623,166 Ensembl chrNW_004624738:2,618,738...2,623,166
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Xrcc1
X-ray repair cross complementing 1
susceptibility
ISO
associated with Human Viral Hepatitis;DNA:missense mutation:cds:p.R399Q (rs25487) (human) associated with hepatitis B;DNA:missense mutation, haplotype:cds:p.R399Q (human) associated with Hepatitis C, Chronic;DNA:missense mutation:cds:p.R194W (human)
RGD
PMID:23454624 PMID:24018491 PMID:29935355
RGD:14985244 RGD:15036794 RGD:15036797
NCBI chrNW_004624907:1,087,611...1,113,275
Ensembl chrNW_004624907:1,087,611...1,113,266
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Aldh2
aldehyde dehydrogenase 2 family member
susceptibility
ISO
associated with alcohol dependence;DNA:missense mutation:exon 12:p.E487K (human) DNA:missense mutation:cds: (rs671) (human) DNA:missense mutation:cds:p.E504K (human)
RGD
PMID:11051375 PMID:23550892 PMID:29779728
RGD:14696777 RGD:15042858 RGD:15042864
NCBI chrNW_004624747:20,407,190...20,438,605
Ensembl chrNW_004624747:20,403,717...20,438,690
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Bcl2
BCL2 apoptosis regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23274713
NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344
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C3
complement C3
ISO
RGD
PMID:9176087
RGD:408418722
NCBI chrNW_004624828:3,773,816...3,798,077
Ensembl chrNW_004624828:3,770,221...3,797,946
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Cat
catalase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23274713
NCBI chrNW_004624767:12,680,940...12,715,468
Ensembl chrNW_004624767:12,680,953...12,715,739
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Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
ISO
protein:decreased expression:brain
RGD
PMID:16205370
RGD:6483345
NCBI chrNW_004624795:1,856,455...1,861,142
Ensembl chrNW_004624795:1,855,992...1,861,053
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Col3a1
collagen type III alpha 1 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23274713
NCBI chrNW_004624899:1,192,078...1,230,528
Ensembl chrNW_004624899:1,192,360...1,230,404
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Crp
C-reactive protein
severity
ISO
RGD
PMID:22441510
RGD:6482305
NCBI chrNW_004624794:1,531,555...1,533,804
Ensembl chrNW_004624794:1,531,571...1,533,804
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Ddr1
discoidin domain receptor tyrosine kinase 1
severity
ISO
mRNA:increased expression:liver (human)
RGD
PMID:33173221
RGD:151347691
NCBI chrNW_004624754:24,881,439...24,905,633
Ensembl chrNW_004624754:24,880,496...24,896,995
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Ddr2
discoidin domain receptor tyrosine kinase 2
disease_progression ameliorates
ISO
RGD
PMID:21199726 PMID:23409069
RGD:150429766 RGD:150517731
NCBI chrNW_004624826:1,225,217...1,255,889
Ensembl chrNW_004624826:1,173,621...1,249,692
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Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma2
susceptibility
ISO
DNA:SNP:intron 8:84435G>A (human)
RGD
PMID:19428381
RGD:402463950
NCBI chrNW_004624733:27,506,827...27,593,750
Ensembl chrNW_004624733:27,504,660...27,594,039
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Il18bp
interleukin 18 binding protein
ISO
protein:increased expression:plasma:
RGD
PMID:15566508
RGD:14696666
NCBI chrNW_004624817:4,963,586...4,967,122
Ensembl chrNW_004624817:4,964,403...4,965,944
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Il6
interleukin 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23274713
NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318
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Jak2
Janus kinase 2
ISO
mRNA, protein:increased expression, increased tyrosine phosphorylation:liver
RGD
PMID:24619965
RGD:10403061
NCBI chrNW_004624736:9,724,876...9,827,364
Ensembl chrNW_004624736:9,724,369...9,830,365
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Lep
leptin
ISO
DNA:hypomethylation:promoter (human)
RGD
PMID:29912265
RGD:21201248
NCBI chrNW_004624783:7,708,820...7,721,610
Ensembl chrNW_004624783:7,708,588...7,721,727
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LOC101722366
cytochrome P450 2E1
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20843640 PMID:29404441
RGD:14700873
NCBI chrNW_004624737:12,335,733...12,345,278
Ensembl chrNW_004624737:12,335,681...12,345,514
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Mboat7
membrane bound O-acyltransferase domain containing 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26482880
NCBI chrNW_004624832:2,407,110...2,417,566
Ensembl chrNW_004624832:2,407,196...2,417,574
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Mmp13
matrix metallopeptidase 13
ISO
RGD
PMID:16286264
RGD:10043176
NCBI chrNW_004624918:2,228,688...2,239,852
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Mmp2
matrix metallopeptidase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23274713
NCBI chrNW_004624757:1,450,680...1,479,160
Ensembl chrNW_004624757:1,448,698...1,479,255
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Mpo
myeloperoxidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19731237 PMID:23274713
NCBI chrNW_004624871:121,026...131,433
Ensembl chrNW_004624871:121,026...131,323
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Mthfr
methylenetetrahydrofolate reductase
susceptibility
ISO
DNA:SNP: :677C>T(human)
RGD
PMID:25987440
RGD:14696749
NCBI chrNW_004624818:1,184,736...1,202,708
Ensembl chrNW_004624818:1,187,869...1,199,168
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Nr1d1
nuclear receptor subfamily 1 group D member 1
ISO
RGD
PMID:24497272
RGD:10448995
NCBI chrNW_004624795:3,102,424...3,109,497
Ensembl chrNW_004624795:3,102,439...3,109,497
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Plau
plasminogen activator, urokinase
ISO
RGD
PMID:19615318
RGD:7241800
NCBI chrNW_004624754:7,405,637...7,415,870
Ensembl chrNW_004624754:7,408,983...7,416,559
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Rela
RELA proto-oncogene, NF-kB subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23274713
NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272
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Serpine1
serpin family E member 1
susceptibility
ISO
DNA:polymorphism:promoter:
RGD
PMID:25987440
RGD:14696749
NCBI chrNW_004624740:16,128,145...16,136,696
Ensembl chrNW_004624740:16,128,059...16,137,337
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Serpinf1
serpin family F member 1
ISO
protein:increased expression:serum (human)
RGD
PMID:27748324
RGD:27226704
NCBI chrNW_004624786:4,487,005...4,497,706
Ensembl chrNW_004624786:4,486,978...4,497,585
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Smad3
SMAD family member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23274713
NCBI chrNW_004624781:5,795,652...5,890,047
Ensembl chrNW_004624781:5,795,652...5,890,371
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Sod2
superoxide dismutase 2
susceptibility
ISO
DNA:SNP: : 47T>C(human) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:19731237 PMID:26873981
RGD:11060603
NCBI chrNW_004624855:3,260,800...3,271,864
Ensembl chrNW_004624855:3,260,809...3,271,367
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Tg
thyroglobulin
ISO
RGD
PMID:6883738
RGD:401976502
NCBI chrNW_004624735:22,864,373...23,083,457
Ensembl chrNW_004624735:22,862,443...23,083,475
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Tgfb1
transforming growth factor beta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23274713
NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605
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Timp1
TIMP metallopeptidase inhibitor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23274713
NCBI chrNW_004624978:120,723...125,006
Ensembl chrNW_004624978:121,803...124,912
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Tm6sf2
transmembrane 6 superfamily member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26482880
NCBI chrNW_004624908:2,136,563...2,143,574
Ensembl chrNW_004624908:2,136,747...2,143,560
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Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23274713
NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531
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Aqp4
aquaporin 4
ISO
RGD
PMID:20680636
RGD:5148026
NCBI chrNW_004624770:5,581,192...5,593,470
Ensembl chrNW_004624770:5,580,808...5,594,628
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Edar
ectodysplasin A receptor
ISO
ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy
ClinVar
PMID:10431241 PMID:18231121 PMID:20236127 PMID:20979233 PMID:25741868 PMID:28492532 More...
NCBI chrNW_004624749:11,981,782...11,998,933
Ensembl chrNW_004624749:11,983,550...11,998,918
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Fanci
FA complementation group I
ISO
ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy
ClinVar
PMID:15477547 PMID:15689359 PMID:16177225 PMID:16621917 PMID:17088268 PMID:17426723 PMID:17438011 PMID:17452773 PMID:17460694 PMID:17950645 PMID:17980715 PMID:18414213 PMID:18546365 PMID:18991199 PMID:19010300 PMID:19538466 PMID:20691285 PMID:21038416 PMID:21228398 PMID:21880868 PMID:22189570 PMID:23430898 PMID:23524600 PMID:23783014 PMID:24033266 PMID:24086434 PMID:25462018 PMID:25741868 PMID:26104464 PMID:26467025 PMID:27987238 PMID:28492532 PMID:30423451 PMID:30634555 PMID:31655921 PMID:33486010 PMID:35478072 More...
NCBI chrNW_004624768:16,427,060...16,493,850
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LOC101698338
E3 SUMO-protein ligase RanBP2
ISO
ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy
ClinVar
PMID:10431241 PMID:18231121 PMID:20236127 PMID:20979233 PMID:25741868 PMID:28492532 More...
NCBI chrNW_004624749:11,862,670...11,923,291
Ensembl chrNW_004624749:11,862,760...11,923,958
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Polg
DNA polymerase gamma, catalytic subunit
susceptibility
ISO
ClinVar Annotator: match by term: Alpers-Huttenlocher Syndrome | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4a | ClinVar Annotator: match by term: Neuronal degeneration of childhood with liver disease, progressive | ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy ClinVar Annotator: match by term: Alpers disease | ClinVar Annotator: match by term: Alpers-Huttenlocher Syndrome | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4a | ClinVar Annotator: match by term: Neuronal degeneration of childhood with liver disease, progressive | ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy ClinVar Annotator: match by term: Alpers diffuse degeneration of cerebral gray matter with hepatic cirrhosis | ClinVar Annotator: match by term: Alpers-Huttenlocher Syndrome | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4A (Alpers type) | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4a | ClinVar Annotator: match by term: Neuronal degeneration of childhood with liver disease, progressive | ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy ClinVar Annotator: match by term: Alpers progressive infantile poliodystrophy | ClinVar Annotator: match by term: Alpers-Huttenlocher Syndrome | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4a | ClinVar Annotator: match by term: Neuronal degeneration of childhood with liver disease, progressive | ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy ClinVar Annotator: match by term: Alpers diffuse degeneration of cerebral gray matter with hepatic cirrhosis | ClinVar Annotator: match by term: Alpers-Huttenlocher Syndrome | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4a | ClinVar Annotator: match by term: Neuronal degeneration of childhood with liver disease, progressive | ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy ClinVar Annotator: match by term: Alpers Syndrome | ClinVar Annotator: match by term: Alpers-Huttenlocher Syndrome | ClinVar Annotator: match by term: Mitochondrial DNA depletion syndrome 4a | ClinVar Annotator: match by term: Neuronal degeneration of childhood with liver disease, progressive | ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy DNA:missense mutation:cds:p.P1073L (3218C>T) (human)
OMIM ClinVar RGD
PMID:632821 PMID:1539879 PMID:1582434 PMID:1858914 PMID:2067633 PMID:2392416 PMID:2504279 PMID:2725645 PMID:7847370 PMID:9500334 PMID:9536098 PMID:11301032 PMID:11431686 PMID:11555352 PMID:11571332 PMID:11897778 PMID:12073019 PMID:12210792 PMID:12297582 PMID:12565911 PMID:12707443 PMID:12825077 PMID:12872260 PMID:12975295 PMID:14467368 PMID:14557557 PMID:14635118 PMID:14694057 PMID:14745080 PMID:15122711 PMID:15181170 PMID:15258572 PMID:15349879 PMID:15351195 PMID:15477547 PMID:15534189 PMID:15689359 PMID:15800909 PMID:15824347 PMID:15913923 PMID:15917273 PMID:15929042 PMID:16024923 PMID:16080118 PMID:16130100 PMID:16177225 PMID:16199547 PMID:16368709 PMID:16401742 PMID:16545482 PMID:16595552 PMID:16621917 PMID:16634032 PMID:16638794 PMID:16639411 PMID:16682683 PMID:16715201 PMID:16857757 PMID:16896309 PMID:16919951 PMID:16929381 PMID:16940310 PMID:16943369 PMID:16957900 PMID:17067213 PMID:17088268 PMID:17280874 PMID:17310215 PMID:17418573 PMID:17426723 PMID:17436221 PMID:17438011 PMID:17452231 PMID:17452773 PMID:17460694 PMID:17502560 PMID:17538929 PMID:17576681 PMID:17725985 PMID:17846414 PMID:17894835 PMID:17923349 PMID:17950645 PMID:17980715 PMID:18156159 PMID:18195149 PMID:18195151 PMID:18294203 PMID:18321754 PMID:18414213 PMID:18446447 PMID:18487244 PMID:18500570 PMID:18546343 PMID:18546365 PMID:18585914 PMID:18716558 PMID:18783964 PMID:18828154 PMID:18991199 PMID:19010300 PMID:19103152 PMID:19125351 PMID:19189930 PMID:19195941 PMID:19251978 PMID:19275594 PMID:19307547 PMID:19344718 PMID:19364868 PMID:19478085 PMID:19500334 PMID:19501198 PMID:19538466 PMID:19566497 PMID:19578034 PMID:19629138 PMID:19752458 PMID:19762913 PMID:19766516 PMID:19813183 PMID:19815814 PMID:19837034 PMID:19862739 PMID:19887119 PMID:20138553 PMID:20142534 PMID:20153822 PMID:20176107 PMID:20185557 PMID:20220442 PMID:20227526 PMID:20301791 PMID:20385918 PMID:20400524 PMID:20434700 PMID:20438629 PMID:20513108 PMID:20513922 PMID:20576279 PMID:20601675 PMID:20691285 PMID:20701905 PMID:20803511 PMID:20818383 PMID:20837861 PMID:20837862 PMID:20843780 PMID:20883824 PMID:20981092 PMID:21038416 PMID:21138766 PMID:21228000 PMID:21228398 PMID:21235791 PMID:21236670 PMID:21259344 PMID:21276947 PMID:21282586 PMID:21301859 PMID:21305355 PMID:21357833 PMID:21447491 PMID:21455106 PMID:21484424 PMID:21515089 PMID:21550804 PMID:21647632 PMID:21654874 PMID:21670405 PMID:21686371 PMID:21696159 PMID:21704543 PMID:21824913 PMID:21856450 PMID:21880868 PMID:21953457 PMID:21956653 PMID:21993618 PMID:22000311 PMID:22006280 PMID:22084276 PMID:22114710 PMID:22166854 PMID:22189570 PMID:22215559 PMID:22237560 PMID:22277967 PMID:22334187 PMID:22342071 PMID:22357363 PMID:22377773 PMID:22470557 PMID:22494076 PMID:22537151 PMID:22552686 PMID:22616202 PMID:22647225 PMID:22711370 PMID:22727047 PMID:22778364 PMID:22805437 PMID:22863191 PMID:22931735 PMID:22933815 PMID:22980518 PMID:22987704 PMID:22995991 PMID:23066759 PMID:23077218 PMID:23084792 PMID:23208208 PMID:23212759 PMID:23248042 PMID:23250882 PMID:23251356 PMID:23299917 PMID:23324391 PMID:23419467 PMID:23426270 PMID:23430834 PMID:23430898 PMID:23446635 PMID:23446645 PMID:23448099 PMID:23524600 PMID:23545419 PMID:23596069 PMID:23665194 PMID:23719791 PMID:23783014 PMID:23804100 PMID:23808377 PMID:23811324 PMID:23830586 PMID:23836942 PMID:23873972 PMID:23921535 PMID:24033266 PMID:24086434 PMID:24091540 PMID:24099403 PMID:24122062 PMID:24194468 PMID:24259288 PMID:24265579 PMID:24266892 PMID:24272679 PMID:24288107 PMID:24331360 PMID:24398692 PMID:24508722 PMID:24642831 PMID:24725338 PMID:24841123 PMID:25025039 PMID:25065347 PMID:25118206 PMID:25129007 PMID:25193669 PMID:25203713 PMID:25281868 PMID:25286830 PMID:25340760 PMID:25356970 PMID:25412673 PMID:25429852 PMID:25462018 PMID:25466440 PMID:25488682 PMID:25497598 PMID:25525159 PMID:25585994 PMID:25638290 PMID:25660390 PMID:25713120 PMID:25724872 PMID:25741868 PMID:25741916 PMID:25742477 PMID:25771874 PMID:25850945 PMID:25852747 PMID:25914719 PMID:25940035 PMID:26050231 PMID:26077851 PMID:26095671 PMID:26104464 PMID:26132555 PMID:26169155 PMID:26224072 PMID:26337858 PMID:26357557 PMID:26467025 PMID:26468652 PMID:26554610 PMID:26557169 PMID:26607151 PMID:26640698 PMID:26735972 PMID:26742794 PMID:26755490 PMID:26942291 PMID:26942292 PMID:26968897 PMID:27016405 PMID:27101133 PMID:27111573 PMID:27119776 PMID:27185166 PMID:27271921 PMID:27290639 PMID:27345795 PMID:27349602 PMID:27381400 PMID:27422324 PMID:27450679 PMID:27475922 PMID:27527004 PMID:27538604 PMID:27538665 PMID:27822509 PMID:27826120 PMID:27838477 PMID:27843123 PMID:27917773 PMID:27987238 PMID:28074849 PMID:28128857 PMID:28130605 PMID:28154168 PMID:28206745 PMID:28337550 PMID:28430993 PMID:28444220 PMID:28471437 PMID:28480171 PMID:28492532 PMID:28634151 PMID:28756246 PMID:28771251 PMID:28776642 PMID:28812649 PMID:28815208 PMID:28837072 PMID:28865037 PMID:28901595 PMID:28958595 PMID:29029963 PMID:29190809 PMID:29214156 PMID:29272804 PMID:29278894 PMID:29302508 PMID:29341116 PMID:29358615 PMID:29423831 PMID:29431110 PMID:29474836 PMID:29482223 PMID:29574624 PMID:29588995 PMID:29644085 PMID:29655203 PMID:29712893 PMID:29913018 PMID:29915382 PMID:29920680 PMID:29950568 PMID:29992832 PMID:29997391 PMID:30009132 PMID:30021052 PMID:30167885 PMID:30255931 PMID:30290626 PMID:30306720 PMID:30369941 PMID:30373890 PMID:30385167 PMID:30393377 PMID:30404819 PMID:30423451 PMID:30451971 PMID:30487145 PMID:30552426 PMID:30609409 PMID:30634555 PMID:30637288 PMID:30678510 PMID:30755392 PMID:30818899 PMID:30831263 PMID:30838265 PMID:30843307 PMID:30860128 PMID:30936349 PMID:30941926 PMID:30951992 PMID:31075681 PMID:31085725 PMID:31130284 PMID:31147703 PMID:31164858 PMID:31209396 PMID:31359948 PMID:31425757 PMID:31475037 PMID:31521625 PMID:31571979 PMID:31589614 PMID:31613174 PMID:31645654 PMID:31655921 PMID:31658717 PMID:31665838 PMID:31669236 PMID:31694722 PMID:31731261 PMID:31762033 PMID:31980526 PMID:31996268 PMID:32005694 PMID:32019516 PMID:32042919 PMID:32161153 PMID:32165824 PMID:32234506 PMID:32305867 PMID:32347949 PMID:32348839 PMID:32364361 PMID:32382377 PMID:32391929 PMID:32445240 PMID:32502631 PMID:32504279 PMID:32531456 PMID:32567010 PMID:32600829 PMID:32613234 PMID:32668698 PMID:32703289 PMID:32964447 PMID:33046616 PMID:33233646 PMID:33258288 PMID:33278787 PMID:33396418 PMID:33434755 PMID:33469851 PMID:33473333 PMID:33486010 PMID:33513296 PMID:33579567 PMID:33600046 PMID:33671400 PMID:33683010 PMID:33726816 PMID:33791913 PMID:33956154 PMID:34008892 PMID:34052969 PMID:34062649 PMID:34189666 PMID:34194468 PMID:34426522 PMID:34670123 PMID:34690748 PMID:34777884 PMID:34782754 PMID:34927673 PMID:35101151 PMID:35114397 PMID:35186329 PMID:35289132 PMID:35307828 PMID:35350396 PMID:35478072 PMID:35488641 PMID:35598585 PMID:35641312 PMID:35699875 PMID:35760101 PMID:35799515 PMID:35811324 PMID:35861376 PMID:36065636 PMID:36325100 PMID:36332611 PMID:36403551 PMID:36689859 PMID:36703223 PMID:36987741 PMID:37091313 PMID:37184518 PMID:37189790 PMID:38294884 More...
RGD:15039298
NCBI chrNW_004624768:16,493,123...16,509,747
Ensembl chrNW_004624768:16,491,555...16,509,900
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Polrmt
RNA polymerase mitochondrial
ISO
ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy
ClinVar
PMID:25741868
NCBI chrNW_004624828:7,876,682...7,888,990
Ensembl chrNW_004624828:7,876,739...7,888,923
G
Rlbp1
retinaldehyde binding protein 1
ISO
ClinVar Annotator: match by term: Progressive sclerosing poliodystrophy
ClinVar
PMID:2392416 PMID:11301032 PMID:21447491 PMID:25429852 PMID:28492532
NCBI chrNW_004624768:16,410,328...16,423,722
Ensembl chrNW_004624768:16,406,925...16,421,385
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Ace
angiotensin I converting enzyme
ISO
protein:increased expression:serum (human)
RGD
PMID:21290180
RGD:25671452
NCBI chrNW_004624849:998,262...1,019,305
Ensembl chrNW_004624849:998,277...1,019,521
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Itgb3
integrin subunit beta 3
ISO
DNA:missense mutation: :p.L33P (human)
RGD
PMID:18685811
RGD:10755472
NCBI chrNW_004624849:1,895,378...1,952,755
Ensembl chrNW_004624849:1,895,914...1,952,665
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Mthfr
methylenetetrahydrofolate reductase
susceptibility
ISO
DNA:SNPs: :DNA:SNPs: :677C>T, 1298A>C(human)
RGD
PMID:18685811
RGD:10755472
NCBI chrNW_004624818:1,184,736...1,202,708
Ensembl chrNW_004624818:1,187,869...1,199,168
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Serpine1
serpin family E member 1
susceptibility
ISO
DNA:polymorphism:promoter:
RGD
PMID:18685811
RGD:10755472
NCBI chrNW_004624740:16,128,145...16,136,696
Ensembl chrNW_004624740:16,128,059...16,137,337
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Ace
angiotensin I converting enzyme
ISO
associated with Polycystic Kidney, Autosomal Recessive;mRNA:increased expression:liver
RGD
PMID:20400910
RGD:2325215
NCBI chrNW_004624849:998,262...1,019,305
Ensembl chrNW_004624849:998,277...1,019,521
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Pkhd1
PKHD1 ciliary IPT domain containing fibrocystin/polyductin
ISO
DNA:mutations:cds:c.7994T>C, p.(Leu2665Pro),c.8518C>T, p.(Arg2840Cys)(human)
RGD
PMID:30507656 PMID:30600684
RGD:14700919 RGD:14700992
NCBI chrNW_004624855:4,019,088...4,539,289
Ensembl chrNW_004624855:4,019,056...4,536,324
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Ctla4
cytotoxic T-lymphocyte associated protein 4
susceptibility
ISO
DNA:SNP: :-318C>T(human)
RGD
PMID:18049163
RGD:14398738
NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324
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Krt18
keratin 18
ISO
ClinVar Annotator: match by term: Cirrhosis, cryptogenic
ClinVar
PMID:9011570 PMID:12724528
NCBI chrNW_004624904:1,011,675...1,015,319
Ensembl chrNW_004624904:1,011,755...1,015,416
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Krt8
keratin 8
ISO
ClinVar Annotator: match by term: Cirrhosis, cryptogenic
ClinVar
PMID:9011570 PMID:11372009 PMID:12724528 PMID:15235035 PMID:25741868 PMID:28492532 PMID:33116287 More...
NCBI chrNW_004624904:970,136...978,211
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Aadat
aminoadipate aminotransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624769:1,586,036...1,611,092
Ensembl chrNW_004624769:1,581,727...1,610,793
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Abat
4-aminobutyrate aminotransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624824:6,112,644...6,202,936
Ensembl chrNW_004624824:6,141,213...6,202,936
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Abcc2
ATP binding cassette subfamily C member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:11,593,701...11,686,790
Ensembl chrNW_004624737:11,593,864...11,688,460
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Abcc5
ATP binding cassette subfamily C member 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:72,529,299...72,621,108
Ensembl chrNW_004624730:72,534,329...72,623,263
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Abcg1
ATP binding cassette subfamily G member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624745:28,137,140...28,188,670
Ensembl chrNW_004624745:28,104,744...28,188,704
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Abcg5
ATP binding cassette subfamily G member 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624738:25,287,574...25,310,643
Ensembl chrNW_004624738:25,287,841...25,309,828
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Abcg8
ATP binding cassette subfamily G member 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624738:25,310,740...25,330,097
Ensembl chrNW_004624738:25,310,917...25,329,595
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Ablim3
actin binding LIM protein family member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624774:8,510,132...8,631,034
Ensembl chrNW_004624774:8,510,907...8,629,090
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Acat1
acetyl-CoA acetyltransferase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624784:2,833,344...2,879,043
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Acbd4
acyl-CoA binding domain containing 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624795:264,161...269,789
Ensembl chrNW_004624795:266,527...270,526
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Ace
angiotensin I converting enzyme
severity
ISO
protein:increased activity:plasma (human) mRNA:increased expression:liver (rat) mRNA: increased expression:liver (rat)
RGD
PMID:8445218 PMID:19424597 PMID:23663763 PMID:24035938
RGD:21408579 RGD:25671449 RGD:25671457 RGD:25671458
NCBI chrNW_004624849:998,262...1,019,305
Ensembl chrNW_004624849:998,277...1,019,521
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Ace2
angiotensin converting enzyme 2
ISO
protein:increased expression:liver mRNA, protein:increased expression, increased activity:liver (rat)
RGD
PMID:16166274 PMID:19793108
RGD:2316776 RGD:40818265
NCBI chrNW_004624829:344,823...391,451
Ensembl chrNW_004624829:344,933...391,527
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Ache
acetylcholinesterase (Cartwright blood group)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16496349
NCBI chrNW_004624740:16,275,108...16,280,639
Ensembl chrNW_004624740:16,275,117...16,281,793
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Ackr3
atypical chemokine receptor 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624847:2,189,167...2,200,355
Ensembl chrNW_004624847:2,189,257...2,200,352
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Acot9
acyl-CoA thioesterase 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624897:125,348...155,557
Ensembl chrNW_004624897:125,348...155,621
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Acox2
acyl-CoA oxidase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624822:5,535,086...5,561,867
Ensembl chrNW_004624822:5,536,421...5,561,781
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Acp5
acid phosphatase 5, tartrate resistant
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624828:3,305,913...3,309,983
Ensembl chrNW_004624828:3,307,635...3,310,547
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Acsl1
acyl-CoA synthetase long chain family member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624769:15,503,757...15,584,741
Ensembl chrNW_004624769:15,503,757...15,584,777
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Acta2
actin alpha 2, smooth muscle
ISO
CTD Direct Evidence: marker/mechanism associated with Schistosomiasis Japonica; mRNA:increased expression:liver (rat)
CTD RGD
PMID:26435214 PMID:26739621 PMID:29323718
RGD:38599216
NCBI chrNW_004624791:15,243,074...15,259,362
Ensembl chrNW_004624791:15,242,432...15,259,508
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Actn1
actinin alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:32,097,364...32,190,162
Ensembl chrNW_004624734:32,097,671...32,192,729
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Acvr2a
activin A receptor type 2A
ISO
mRNA:decreased expression:liver
RGD
PMID:12706302
RGD:2325237
NCBI chrNW_004624866:539,967...619,575
Ensembl chrNW_004624866:539,894...620,302
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Ada
adenosine deaminase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883
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Adam17
ADAM metallopeptidase domain 17
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624969:212,089...254,532
Ensembl chrNW_004624969:212,321...253,328
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Add3
adducin 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:36,091,671...36,256,398
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Adgre1
adhesion G protein-coupled receptor E1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624828:3,930,483...3,981,966
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Adhfe1
alcohol dehydrogenase iron containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624744:24,883,104...24,913,885
Ensembl chrNW_004624744:24,880,010...24,913,873
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Adipoq
adiponectin, C1Q and collagen domain containing
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:14724832
NCBI chrNW_004624730:69,941,963...69,959,266
Ensembl chrNW_004624730:69,941,001...69,957,012
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Adipor2
adiponectin receptor 2
severity
ISO
RGD
PMID:29237572
RGD:24922203
NCBI chrNW_004624735:11,103,082...11,174,277
Ensembl chrNW_004624735:11,103,076...11,174,337
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Adm
adrenomedullin
ISO
protein:increased expression:plasma CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:15370692 PMID:16610064 PMID:16713642
RGD:1625319
NCBI chrNW_004624766:2,402,152...2,404,343
Ensembl chrNW_004624766:2,401,769...2,404,446
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Adora2a
adenosine A2a receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16783407
NCBI chrNW_004624747:9,846,254...9,860,938
Ensembl chrNW_004624747:9,851,153...9,860,094
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Adora3
adenosine A3 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624772:7,189,381...7,232,919
Ensembl chrNW_004624772:7,229,093...7,232,837
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Adra1b
adrenoceptor alpha 1B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624733:29,545,870...29,661,954
Ensembl chrNW_004624733:29,545,789...29,662,028
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Adrb1
adrenoceptor beta 1
ISO
mRNA, protein:increased expression:liver
RGD
PMID:19785950
RGD:5129118
NCBI chrNW_004624737:32,536,096...32,563,721
Ensembl chrNW_004624737:32,541,598...32,563,424
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Adrb2
adrenoceptor beta 2
ISO
mRNA, protein:increased expression:liver
RGD
PMID:19785950
RGD:5129118
NCBI chrNW_004624774:8,211,723...8,215,962
Ensembl chrNW_004624774:8,211,984...8,213,240
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Adrb3
adrenoceptor beta 3
ISO
mRNA, protein:increased expression:liver
RGD
PMID:19785950
RGD:5129118
NCBI chrNW_004624780:5,653,499...5,656,138
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Aen
apoptosis enhancing nuclease
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624768:15,931,607...15,940,690
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Afm
afamin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624735:33,945,107...34,015,900
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Afp
alpha fetoprotein
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:17072980 PMID:30346985
RGD:151665755
NCBI chrNW_004624735:34,072,257...34,092,540
Ensembl chrNW_004624735:34,072,192...34,092,604
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Agfg1
ArfGAP with FG repeats 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624843:1,751,735...1,806,624
Ensembl chrNW_004624843:1,751,808...1,806,631
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Agl
amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624857:2,629,158...2,730,764
Ensembl chrNW_004624857:2,629,313...2,728,196
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Agt
angiotensinogen
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12667390
NCBI chrNW_004624775:18,846,222...18,856,093
Ensembl chrNW_004624775:18,849,118...18,855,577
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Agtr1
angiotensin II receptor type 1
treatment
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:12890498 PMID:24619965 PMID:25380136
RGD:10403061
NCBI chrNW_004624730:25,964,848...26,006,468
Ensembl chrNW_004624730:25,964,811...26,006,463
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Ahnak
AHNAK nucleoprotein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624926:1,071,969...1,101,587
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Aida
axin interactor, dorsalization associated
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624835:5,206,365...5,240,534
Ensembl chrNW_004624835:5,207,011...5,240,269
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Aif1
allograft inflammatory factor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:24,590,071...24,591,913
Ensembl chrNW_004624754:24,590,071...24,591,904
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Akt1
AKT serine/threonine kinase 1
ISO
protein:increased phosphorylation:liver
RGD
PMID:31671832
RGD:407987423
NCBI chrNW_004624734:507,880...525,295
Ensembl chrNW_004624734:509,368...525,295
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Aktip
AKT interacting protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624757:3,265,492...3,295,406
Ensembl chrNW_004624757:3,265,389...3,294,735
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Alb
albumin
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16642209 PMID:17963606 PMID:21163135 PMID:30346985
RGD:151665755
NCBI chrNW_004624735:34,105,237...34,123,479
Ensembl chrNW_004624735:34,104,537...34,123,624
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Aldh1a1
aldehyde dehydrogenase 1 family member A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624811:505,297...563,795
Ensembl chrNW_004624811:505,101...563,855
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Aldh1b1
aldehyde dehydrogenase 1 family member B1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15650968 PMID:25380136
NCBI chrNW_004624825:3,538,210...3,539,640
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Aldh1l1
aldehyde dehydrogenase 1 family member L1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15650968
NCBI chrNW_004624773:385,583...468,270
Ensembl chrNW_004624773:385,594...468,270
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Aldh1l2
aldehyde dehydrogenase 1 family member L2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624750:3,912,030...4,054,170
Ensembl chrNW_004624750:3,912,002...3,961,963
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Aldh2
aldehyde dehydrogenase 2 family member
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15650968
NCBI chrNW_004624747:20,407,190...20,438,605
Ensembl chrNW_004624747:20,403,717...20,438,690
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Amacr
alpha-methylacyl-CoA racemase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624759:20,495,697...20,506,343
Ensembl chrNW_004624759:20,495,980...20,510,582
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Angpt1
angiopoietin 1
disease_progression
ISO
protein:increased expression:liver
RGD
PMID:17935226
RGD:1643338
NCBI chrNW_004624763:22,645,807...22,818,592
Ensembl chrNW_004624763:22,646,231...22,718,294
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Angpt2
angiopoietin 2
ISO
mRNA, protein:increased expression:multiple organs (rat)
RGD
PMID:18978178
RGD:2314174
NCBI chrNW_004624861:4,457,519...4,510,035
Ensembl chrNW_004624861:4,457,158...4,509,623
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Angptl3
angiopoietin like 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624742:31,261,719...31,269,877
Ensembl chrNW_004624742:31,260,611...31,270,122
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Ano6
anoctamin 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624816:6,896,176...7,077,758
Ensembl chrNW_004624816:6,894,413...7,077,883
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Anp32a
acidic nuclear phosphoprotein 32 family member A
treatment
ISO
RGD
PMID:19054144
RGD:10401133
NCBI chrNW_004624781:4,365,378...4,477,004
Ensembl chrNW_004624781:4,441,238...4,477,004
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Anxa1
annexin A1
ISO
mRNA:increased expression:liver CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:8755646 PMID:25380136
RGD:2306954
NCBI chrNW_004624811:765,338...782,203
Ensembl chrNW_004624811:764,940...782,198
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Anxa2
annexin A2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624781:11,781,893...11,820,440
Ensembl chrNW_004624781:11,781,886...11,821,816
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Anxa3
annexin A3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624757:12,442,577...12,505,367
Ensembl chrNW_004624757:12,442,577...12,502,903
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Anxa4
annexin A4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624762:3,562,656...3,641,465
Ensembl chrNW_004624762:3,562,446...3,641,770
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Anxa5
annexin A5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624777:1,921,354...1,969,772
Ensembl chrNW_004624777:1,919,602...1,970,059
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Ap1s2
adaptor related protein complex 1 subunit sigma 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624829:608,065...637,096
Ensembl chrNW_004624829:608,065...634,479
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Ap3s1
adaptor related protein complex 3 subunit sigma 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624733:5,979,644...6,045,777
Ensembl chrNW_004624733:5,979,734...6,045,721
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Apaf1
apoptotic peptidase activating factor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624750:8,835,521...8,940,957
Ensembl chrNW_004624750:8,837,037...8,938,009
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Apbb1ip
amyloid beta precursor protein binding family B member 1 interacting protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624796:2,512,292...2,621,505
Ensembl chrNW_004624796:2,510,878...2,568,532
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Apmap
adipocyte plasma membrane associated protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624939:441,621...468,546
Ensembl chrNW_004624939:441,631...470,372
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Apoa1
apolipoprotein A1
ISO
RGD
PMID:2123716
RGD:1599161
NCBI chrNW_004624784:12,249,283...12,251,215
Ensembl chrNW_004624784:12,249,283...12,251,136
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Apoa4
apolipoprotein A4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624784:12,237,329...12,240,013
Ensembl chrNW_004624784:12,233,593...12,239,763
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Apobec1
apolipoprotein B mRNA editing enzyme catalytic subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624860:4,938,001...4,957,640
Ensembl chrNW_004624860:4,938,001...4,957,236
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App
amyloid beta precursor protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624745:13,904,912...14,159,374
Ensembl chrNW_004624745:13,902,577...14,159,372
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Appl1
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624822:31,175...74,252
Ensembl chrNW_004624822:33,880...74,308
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Aqp7
aquaporin 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624736:38,130,992...38,148,444
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Arg1
arginase 1
ISO
mRNA, protein:decreased expression:liver (rat)
RGD
PMID:11931836
RGD:1626298
NCBI chrNW_004624753:5,737,720...5,749,313
Ensembl chrNW_004624753:5,737,237...5,752,966
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Arg2
arginase 2
ISO
mRNA, protein:increased expression:liver
RGD
PMID:11931836
RGD:1626298
NCBI chrNW_004624734:33,321,161...33,352,306
Ensembl chrNW_004624734:33,321,295...33,352,277
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Arhgap30
Rho GTPase activating protein 30
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624794:299,877...317,859
Ensembl chrNW_004624794:300,212...317,073
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Arhgap9
Rho GTPase activating protein 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624802:10,461,014...10,483,148
Ensembl chrNW_004624802:10,475,609...10,483,043
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Arhgdib
Rho GDP dissociation inhibitor beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:23,074,249...23,090,866
Ensembl chrNW_004624752:23,073,680...23,091,313
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Arl11
ARF like GTPase 11
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624748:5,023,391...5,025,389
Ensembl chrNW_004624748:5,023,391...5,025,131
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Arl8a
ARF like GTPase 8A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624807:8,594,097...8,602,640
Ensembl chrNW_004624807:8,593,619...8,602,647
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Armcx1
armadillo repeat containing X-linked 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624902:1,042,766...1,053,131
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Arpc1b
actin related protein 2/3 complex subunit 1B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624740:32,805,647...32,821,986
Ensembl chrNW_004624740:32,805,610...32,821,918
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Arrb2
arrestin beta 2
ISO
CTD Direct Evidence: marker/mechanism protein:increased expression:aorta
CTD RGD
PMID:17256744 PMID:25380136
RGD:1625784
NCBI chrNW_004624786:8,568,102...8,576,445
Ensembl chrNW_004624786:8,568,198...8,577,914
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Asah1
N-acylsphingosine amidohydrolase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624769:21,112,705...21,140,004
Ensembl chrNW_004624769:21,112,851...21,138,831
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Asns
asparagine synthetase (glutamine-hydrolyzing)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624813:4,642,420...4,661,362
Ensembl chrNW_004624813:4,641,372...4,661,778
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Aspn
asporin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624868:3,897,633...3,920,307
Ensembl chrNW_004624868:3,897,514...3,920,383
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Ass1
argininosuccinate synthase 1
ISO
mRNA:decreased expression:liver (rat)
RGD
PMID:19914391
RGD:4140452
NCBI chrNW_004624760:5,180,095...5,221,677
Ensembl chrNW_004624760:5,180,095...5,221,732
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Atf3
activating transcription factor 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624771:18,009,111...18,060,796
Ensembl chrNW_004624771:18,050,039...18,060,802
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Atp10d
ATPase phospholipid transporting 10D (putative)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624761:19,408,249...19,527,007
Ensembl chrNW_004624761:19,407,954...19,527,049
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Atp6v1d
ATPase H+ transporting V1 subunit D
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:33,640,842...33,669,471
Ensembl chrNW_004624734:33,640,839...33,657,745
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Atrn
attractin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624741:4,559,149...4,745,840
Ensembl chrNW_004624741:4,559,121...4,745,996
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Axl
AXL receptor tyrosine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624907:76,236...106,765
Ensembl chrNW_004624907:77,806...106,228
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B2m
beta-2-microglobulin
ISO
protein:increased expression:urine
RGD
PMID:18777138
RGD:6482712
NCBI chrNW_004624804:11,514,728...11,521,625
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B4galt5
beta-1,4-galactosyltransferase 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624790:5,770,586...5,792,036
Ensembl chrNW_004624790:5,766,903...5,789,140
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B9d1
B9 domain containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624849:5,635,996...5,644,139
Ensembl chrNW_004624849:5,633,076...5,644,221
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Bak1
BCL2 antagonist/killer 1
ISO
mRNA:increased expression:liver
RGD
PMID:11232245
RGD:2315709
NCBI chrNW_004624754:23,297,077...23,302,366
Ensembl chrNW_004624754:23,296,800...23,301,223
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Bbox1
gamma-butyrobetaine hydroxylase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624766:16,903,327...16,962,176
Ensembl chrNW_004624766:16,903,323...16,957,584
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Bcl2
BCL2 apoptosis regulator
treatment
ISO
mRNA:increased expression:liver (rat)
RGD
PMID:17938867 PMID:24218972
RGD:10054116 RGD:2293129
NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344
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Bcr
BCR activator of RhoGEF and GTPase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624747:9,528,968...9,664,055
Ensembl chrNW_004624747:9,528,996...9,662,131
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Bdh1
3-hydroxybutyrate dehydrogenase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624730:62,397,242...62,466,172
Ensembl chrNW_004624730:62,397,245...62,424,924
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Bgn
biglycan
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624946:230,529...241,448
Ensembl chrNW_004624946:230,519...241,850
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Bicd2
BICD cargo adaptor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624868:3,598,523...3,649,641
Ensembl chrNW_004624868:3,598,688...3,650,731
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Birc3
baculoviral IAP repeat containing 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624878:516,750...541,475
Ensembl chrNW_004624878:523,300...536,062
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Birc5
baculoviral IAP repeat containing 5
ISO
RGD
PMID:17938867
RGD:2293129
NCBI chrNW_004624801:7,727,084...7,735,946
Ensembl chrNW_004624801:7,727,093...7,735,940
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Bloc1s2
biogenesis of lysosomal organelles complex 1 subunit 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:12,095,175...12,101,595
Ensembl chrNW_004624737:12,094,309...12,102,030
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Blvra
biliverdin reductase A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624740:17,462,201...17,505,725
Ensembl chrNW_004624740:17,462,537...17,478,269
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Bmf
Bcl2 modifying factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624804:7,420,003...7,440,012
Ensembl chrNW_004624804:7,423,547...7,440,014
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Bmp4
bone morphogenetic protein 4
ISO
mRNA, protein:increased expression:liver
RGD
PMID:16447265
RGD:1643229
NCBI chrNW_004624731:15,262,480...15,269,196
Ensembl chrNW_004624731:15,263,274...15,269,743
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Bmp7
bone morphogenetic protein 7
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17127702
NCBI chrNW_004624741:23,658,214...23,743,227
Ensembl chrNW_004624741:23,658,004...23,737,742
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C1qa
complement C1q A chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624764:7,363,615...7,366,408
Ensembl chrNW_004624764:7,363,567...7,366,617
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C1qb
complement C1q B chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624764:7,377,013...7,382,953
Ensembl chrNW_004624764:7,376,967...7,383,445
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C1qc
complement C1q C chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624764:7,369,365...7,373,238
Ensembl chrNW_004624764:7,369,338...7,373,436
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C5ar1
complement C5a receptor 1
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15995705 PMID:25380136
RGD:1600592
NCBI chrNW_004624832:6,413,169...6,423,394
Ensembl chrNW_004624832:6,414,587...6,423,394
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C7
complement C7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624759:13,991,104...14,114,271
Ensembl chrNW_004624759:13,992,681...14,114,411
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C8g
complement C8 gamma chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:937,871...939,655
Ensembl chrNW_004624760:937,871...939,466
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Ca3
carbonic anhydrase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624744:6,202,151...6,211,662
Ensembl chrNW_004624744:6,199,382...6,212,163
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Ca5a
carbonic anhydrase 5A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624746:1,293,619...1,323,067
Ensembl chrNW_004624746:1,293,875...1,315,890
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Capg
capping actin protein, gelsolin like
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624749:17,706,582...17,764,087
Ensembl chrNW_004624749:17,723,715...17,746,346
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Casp4
caspase 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624918:145,661...187,006
G
Casp7
caspase 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:32,853,354...32,888,881
Ensembl chrNW_004624737:32,852,835...32,887,069
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Cav1
caveolin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624827:2,844,855...2,878,367
Ensembl chrNW_004624827:2,844,115...2,879,179
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Ccdc126
coiled-coil domain containing 126
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624739:6,954,636...6,991,715
Ensembl chrNW_004624739:6,953,004...6,991,809
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Ccl5
C-C motif chemokine ligand 5
severity treatment disease_progression
ISO
CTD Direct Evidence: marker/mechanism mRNA,protein:increased expression:liver
CTD RGD
PMID:20978355 PMID:22574195 PMID:25380136 PMID:25617348
RGD:14995328 RGD:14995329 RGD:14995337
NCBI chrNW_004624875:3,334,136...3,342,085
Ensembl chrNW_004624875:3,334,078...3,341,614
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Ccn2
cellular communication network factor 2
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:liver (rat)
CTD RGD
PMID:19856102 PMID:25380136
RGD:2314367
NCBI chrNW_004624753:6,022,033...6,024,866
Ensembl chrNW_004624753:6,023,069...6,024,833
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Ccn4
cellular communication network factor 4
ISO
RGD
PMID:24600972
RGD:10003105
NCBI chrNW_004624735:22,789,784...22,819,527
Ensembl chrNW_004624735:22,788,475...22,819,648
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Ccna2
cyclin A2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624777:2,097,002...2,104,244
G
Ccnb2
cyclin B2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624781:12,875,215...12,905,878
Ensembl chrNW_004624781:12,874,020...12,905,932
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Ccng1
cyclin G1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624733:26,366,448...26,378,062
Ensembl chrNW_004624733:26,367,200...26,376,664
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Cd163
CD163 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624860:3,976,746...4,000,349
Ensembl chrNW_004624860:3,975,747...4,000,349
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Cd24
CD24 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624780:15,287,426...15,292,292
Ensembl chrNW_004624780:15,287,433...15,292,292
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Cd276
CD276 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624781:691,348...703,202
G
Cd36
CD36 molecule (CD36 blood group)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624739:29,341,620...29,441,232
Ensembl chrNW_004624739:29,407,568...29,441,333
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Cd38
CD38 molecule
ISO
mRNA, protein:increased expression:liver CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:16343077 PMID:25380136
RGD:2307239
NCBI chrNW_004624755:16,035,412...16,093,610
Ensembl chrNW_004624755:16,034,771...16,093,866
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Cd48
CD48 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624794:564,425...605,080
Ensembl chrNW_004624794:564,375...605,315
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Cd53
CD53 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624772:6,630,152...6,660,871
Ensembl chrNW_004624772:6,630,123...6,661,599
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Cd5l
CD5 molecule like
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624794:3,060,436...3,071,570
Ensembl chrNW_004624794:3,060,365...3,072,801
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Cd63
CD63 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624802:12,290,733...12,294,293
Ensembl chrNW_004624802:12,290,688...12,342,733
G
Cd68
CD68 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624786:10,195,337...10,197,963
G
Cd7
CD7 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624801:11,108,032...11,112,345
G
Cd74
CD74 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624774:9,699,876...9,708,871
Ensembl chrNW_004624774:9,700,393...9,709,514
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Cd83
CD83 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624756:12,212,921...12,229,974
Ensembl chrNW_004624756:12,210,892...12,229,749
G
Cd86
CD86 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624912:350,201...432,410
Ensembl chrNW_004624912:350,157...426,712
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Cdc42se1
CDC42 small effector 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624772:18,768,765...18,774,859
Ensembl chrNW_004624772:18,768,827...18,774,859
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Cdh1
cadherin 1
ISO
associated with Schistosomiasis Japonica; mRNA:decreased expression:liver (rat)
RGD
PMID:29323718
RGD:38599216
NCBI chrNW_004624746:17,480,472...17,557,722
Ensembl chrNW_004624746:17,483,469...17,557,581
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Cdh5
cadherin 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624746:20,028,952...20,068,029
Ensembl chrNW_004624746:20,033,008...20,057,595
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Cdk1
cyclin dependent kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624791:2,891,239...2,915,001
G
Cdk2
cyclin dependent kinase 2
ISO
RGD
PMID:16534847
RGD:2289284
NCBI chrNW_004624802:12,076,443...12,082,608
Ensembl chrNW_004624802:12,076,443...12,082,630
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Cdk4
cyclin dependent kinase 4
ISO
RGD
PMID:16534847
RGD:2289284
NCBI chrNW_004624802:10,191,679...10,194,585
Ensembl chrNW_004624802:10,191,014...10,194,275
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Cdkn1a
cyclin dependent kinase inhibitor 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:21,109,074...21,115,869
Ensembl chrNW_004624754:21,108,874...21,115,885
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Cdkn2aipnl
CDKN2A interacting protein N-terminal like
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624733:37,875,047...37,887,587
Ensembl chrNW_004624733:37,875,065...37,881,750
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Cdkn3
cyclin dependent kinase inhibitor 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624731:14,838,555...14,853,588
Ensembl chrNW_004624731:14,838,561...14,852,554
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Cdo1
cysteine dioxygenase type 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624733:6,062,716...6,074,583
Ensembl chrNW_004624733:6,062,502...6,075,210
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Cebpd
CCAAT enhancer binding protein delta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624735:7,721,564...7,722,823
Ensembl chrNW_004624735:7,721,633...7,722,445
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Cela1
chymotrypsin like elastase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624816:906,103...939,252
Ensembl chrNW_004624816:906,121...939,696
G
Celf2
CUGBP Elav-like family member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624775:6,017,713...6,557,684
Ensembl chrNW_004624775:6,017,817...6,557,684
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Cemip2
cell migration inducing hyaluronidase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624736:1,296,589...1,367,259
Ensembl chrNW_004624736:1,297,420...1,369,200
G
Cerk
ceramide kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:3,285,649...3,328,131
Ensembl chrNW_004624752:3,285,637...3,326,738
G
Ces3
carboxylesterase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624746:19,303,777...19,333,227
Ensembl chrNW_004624746:19,304,136...19,332,972
G
Cfd
complement factor D
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624828:7,714,926...7,717,139
Ensembl chrNW_004624828:7,711,537...7,717,337
G
Cfp
complement factor properdin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624978:180,352...194,467
Ensembl chrNW_004624978:184,286...190,970
G
Chsy1
chondroitin sulfate synthase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624768:3,567,770...3,628,360
G
Cidea
cell death inducing DFFA like effector a
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624770:19,559,735...19,573,394
Ensembl chrNW_004624770:19,559,692...19,573,788
G
Clec4f
C-type lectin domain family 4 member F
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624762:2,567,854...2,584,329
Ensembl chrNW_004624762:2,567,794...2,584,493
G
Clic1
chloride intracellular channel 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:24,476,262...24,482,529
Ensembl chrNW_004624754:24,476,213...24,482,529
G
Clic2
chloride intracellular channel 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624963:21,115...47,757
G
Clp1
cleavage factor polyribonucleotide kinase subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624864:3,063,555...3,067,045
Ensembl chrNW_004624864:3,063,555...3,067,051
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Cmtm3
CKLF like MARVEL transmembrane domain containing 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624746:19,830,839...19,840,350
Ensembl chrNW_004624746:19,830,839...19,839,430
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Cndp1
carnosine dipeptidase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624806:6,113,052...6,169,943
Ensembl chrNW_004624806:6,113,227...6,169,745
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Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624795:1,856,455...1,861,142
Ensembl chrNW_004624795:1,855,992...1,861,053
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Cnpy4
canopy FGF signaling regulator 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624740:16,872,158...16,877,401
Ensembl chrNW_004624740:16,872,158...16,877,388
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Cnr1
cannabinoid receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17043671
NCBI chrNW_004624799:6,100,709...6,126,530
Ensembl chrNW_004624799:6,101,728...6,126,520
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Col12a1
collagen type XII alpha 1 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624819:2,085,654...2,200,843
Ensembl chrNW_004624819:2,086,512...2,197,951
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Col1a1
collagen type I alpha 1 chain
treatment
ISO
mRNA, protein:increased expression:liver (rat) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:16009107 PMID:20818932 PMID:22706148 PMID:23958495 PMID:25380136 PMID:26435214 PMID:26739621 PMID:30346985 More...
RGD:151665755 RGD:1601595 RGD:5688339 RGD:8552710 RGD:8552768
NCBI chrNW_004624795:6,167,504...6,183,208
Ensembl chrNW_004624795:6,168,797...6,183,071
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Col1a2
collagen type I alpha 2 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:7512265 PMID:25380136
RGD:7257544
NCBI chrNW_004624813:1,174,071...1,209,929
Ensembl chrNW_004624813:1,174,224...1,209,616
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Col3a1
collagen type III alpha 1 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11788567 PMID:25380136
NCBI chrNW_004624899:1,192,078...1,230,528
Ensembl chrNW_004624899:1,192,360...1,230,404
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Col4a1
collagen type IV alpha 1 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624793:2,325,104...2,426,814
Ensembl chrNW_004624793:2,325,128...2,426,817
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Col4a2
collagen type IV alpha 2 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624793:2,201,815...2,325,002
Ensembl chrNW_004624793:2,202,244...2,324,507
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Col5a1
collagen type V alpha 1 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:2,593,923...2,713,772
Ensembl chrNW_004624760:2,593,961...2,713,772
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Col5a2
collagen type V alpha 2 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624899:1,035,797...1,175,394
Ensembl chrNW_004624899:1,035,964...1,174,844
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Col6a1
collagen type VI alpha 1 chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624745:31,125,136...31,140,126
Ensembl chrNW_004624745:31,125,265...31,139,318
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Col6a2
collagen type VI alpha 2 chain
ISO
Protein:increased expression:liver CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:7791542 PMID:25380136
RGD:1600938
NCBI chrNW_004624745:31,246,458...31,272,403
Ensembl chrNW_004624745:31,258,825...31,272,524
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Colec12
collectin subfamily member 12
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624770:10,860,097...11,136,478
Ensembl chrNW_004624770:10,859,205...11,013,175
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Coq10a
coenzyme Q10A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624802:11,726,753...11,740,985
Ensembl chrNW_004624802:11,737,040...11,740,287
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Cotl1
coactosin like F-actin binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624746:1,485,301...1,510,193
Ensembl chrNW_004624746:1,485,321...1,510,276
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Cpq
carboxypeptidase Q
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624763:3,943,816...4,482,111
Ensembl chrNW_004624763:4,051,605...4,450,491
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Cps1
carbamoyl-phosphate synthase 1
ISO
CTD Direct Evidence: marker/mechanism mRNA:decreased expression:liver
CTD RGD
PMID:15650968 PMID:17539997
RGD:2303515
NCBI chrNW_004624765:5,527,029...5,652,343
Ensembl chrNW_004624765:5,528,112...5,651,415
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Creb1
cAMP responsive element binding protein 1
ISO
associated with Chemical and Drug Induced Liver Injury
RGD
PMID:27279449
RGD:401960093
NCBI chrNW_004624765:8,374,160...8,436,969
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Crot
carnitine O-octanoyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624739:34,696,516...34,738,143
Ensembl chrNW_004624739:34,696,511...34,730,419
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Crp
C-reactive protein
ISO
protein:decreased expression:serum:
RGD
PMID:21806828
RGD:9491781
NCBI chrNW_004624794:1,531,555...1,533,804
Ensembl chrNW_004624794:1,531,571...1,533,804
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Crtap
cartilage associated protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624788:11,130,232...11,153,322
Ensembl chrNW_004624788:11,130,278...11,153,965
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Cry1
cryptochrome circadian regulator 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624750:2,465,999...2,529,251
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Cryab
crystallin alpha B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624784:7,074,590...7,093,471
Ensembl chrNW_004624784:7,074,590...7,093,054
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Csad
cysteine sulfinic acid decarboxylase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624904:1,190,393...1,228,337
Ensembl chrNW_004624904:1,189,366...1,228,566
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Csf1r
colony stimulating factor 1 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624774:9,363,156...9,391,939
Ensembl chrNW_004624774:9,363,908...9,391,986
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Csf3
colony stimulating factor 3
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15661404
NCBI chrNW_004624795:3,162,999...3,167,248
Ensembl chrNW_004624795:3,163,009...3,166,594
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Csgalnact1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624758:15,200,726...15,517,146
Ensembl chrNW_004624758:15,200,713...15,367,236
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Ctse
cathepsin E
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624807:5,291,993...5,306,507
Ensembl chrNW_004624807:5,291,736...5,305,104
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Ctss
cathepsin S
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624772:18,421,905...18,446,857
Ensembl chrNW_004624772:18,419,736...18,438,786
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Ctsz
cathepsin Z
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624741:25,280,916...25,301,724
Ensembl chrNW_004624741:25,280,916...25,301,800
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Cttnbp2nl
CTTNBP2 N-terminal like
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624772:8,201,321...8,254,626
Ensembl chrNW_004624772:8,216,556...8,254,626
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CUNH11orf54
chromosome unknown C11orf54 homolog
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624735:38,407,335...38,427,688
Ensembl chrNW_004624735:38,411,829...38,422,981
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CUNH1orf21
chromosome unknown C1orf21 homolog
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624814:9,001,977...9,247,768
Ensembl chrNW_004624814:9,011,202...9,247,610
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CUNH1orf210
chromosome unknown C1orf210 homolog
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624892:2,607,823...2,611,979
Ensembl chrNW_004624892:2,607,383...2,612,216
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CUNH3orf70
chromosome unknown C3orf70 homolog
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:71,431,449...71,534,838
Ensembl chrNW_004624730:71,455,517...71,534,832
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Cxadr
CXADR Ig-like cell adhesion molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624745:5,900,933...5,954,584
Ensembl chrNW_004624745:5,900,886...5,958,765
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Cxcl10
C-X-C motif chemokine ligand 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624757:14,989,241...14,991,650
Ensembl chrNW_004624757:14,989,084...14,991,910
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Cxcl12
C-X-C motif chemokine ligand 12
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624922:1,261,228...1,273,755
Ensembl chrNW_004624922:1,261,228...1,273,758
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Cxcl13
C-X-C motif chemokine ligand 13
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624757:13,488,787...13,494,831
Ensembl chrNW_004624757:13,488,670...13,494,837
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Cxcl16
C-X-C motif chemokine ligand 16
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624786:8,589,687...8,594,059
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Cxcl9
C-X-C motif chemokine ligand 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624757:14,995,649...15,009,771
Ensembl chrNW_004624757:14,995,716...15,011,893
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Cygb
cytoglobin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:16581302
NCBI chrNW_004624801:6,385,771...6,395,705
Ensembl chrNW_004624801:6,384,213...6,395,979
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Cyria
CYFIP related Rac1 interactor A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624865:303,124...430,426
Ensembl chrNW_004624865:343,954...429,915
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Cyrib
CYFIP related Rac1 interactor B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624735:25,752,675...25,894,193
Ensembl chrNW_004624735:25,820,175...25,894,193
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Cystm1
cysteine rich transmembrane module containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624743:32,965,075...33,011,472
Ensembl chrNW_004624743:32,965,527...33,011,361
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Dag1
dystroglycan 1
ISO
mRNA:increased expression:liver
RGD
PMID:12177244
RGD:2314895
NCBI chrNW_004624730:3,417,356...3,488,300
Ensembl chrNW_004624730:3,417,347...3,488,879
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Dao
D-amino acid oxidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624747:12,094,658...12,117,000
Ensembl chrNW_004624747:12,105,133...12,116,604
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Dbh
dopamine beta-hydroxylase
ISO
mRNA:decreased expression:superior mesenteric artery (rat)
RGD
PMID:18457899
RGD:5129683
NCBI chrNW_004624760:2,016,066...2,030,240
Ensembl chrNW_004624760:2,015,474...2,029,939
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Dbndd2
dysbindin domain containing 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624790:9,091,461...9,095,889
Ensembl chrNW_004624790:9,091,461...9,095,722
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Dcxr
dicarbonyl and L-xylulose reductase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624801:10,866,264...10,868,064
Ensembl chrNW_004624801:10,865,219...10,868,060
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Ddc
dopa decarboxylase
ISO
CTD Direct Evidence: marker/mechanism mRNA:decreased expression:superior mesenteric artery (rat)
CTD RGD
PMID:18457899 PMID:25380136
RGD:5129683
NCBI chrNW_004624740:3,674,727...3,732,058
Ensembl chrNW_004624740:3,674,609...3,732,676
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Depdc7
DEP domain containing 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624767:14,185,332...14,204,632
Ensembl chrNW_004624767:14,180,258...14,205,511
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Dhrs3
dehydrogenase/reductase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624818:557,399...590,872
Ensembl chrNW_004624818:557,409...590,872
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Dhrs7
dehydrogenase/reductase 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:40,994,786...41,006,001
Ensembl chrNW_004624734:40,993,587...41,006,074
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Dhtkd1
dehydrogenase E1 and transketolase domain containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624805:4,814,444...4,871,097
Ensembl chrNW_004624805:4,814,546...4,869,359
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Dio1
iodothyronine deiodinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624934:583,302...597,982
Ensembl chrNW_004624934:584,294...597,908
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Dipk2a
divergent protein kinase domain 2A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:20,633,816...20,655,815
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Dock10
dedicator of cytokinesis 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624823:417,567...625,324
Ensembl chrNW_004624823:448,189...624,740
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Dock7
dedicator of cytokinesis 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624742:31,189,890...31,390,284
Ensembl chrNW_004624742:31,189,852...31,390,478
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Dpp7
dipeptidyl peptidase 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:825,992...829,670
Ensembl chrNW_004624760:826,218...830,636
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Dpys
dihydropyrimidinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624763:20,618,515...20,680,790
Ensembl chrNW_004624763:20,620,380...20,680,782
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Dram1
DNA damage regulated autophagy modulator 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624750:6,288,721...6,305,112
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Dus1l
dihydrouridine synthase 1 like
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624801:10,895,983...10,902,804
Ensembl chrNW_004624801:10,895,472...10,902,772
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Dusp16
dual specificity phosphatase 16
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:25,340,997...25,413,561
Ensembl chrNW_004624752:25,340,448...25,413,561
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Dusp6
dual specificity phosphatase 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624750:17,361,725...17,366,907
Ensembl chrNW_004624750:17,362,515...17,367,739
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Dysf
dysferlin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624762:1,936,775...2,166,817
Ensembl chrNW_004624762:1,936,775...2,166,825
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Ece1
endothelin converting enzyme 1
ISO
protein:increased expression:liver
RGD
PMID:16170464
RGD:7243952
NCBI chrNW_004624764:6,222,301...6,318,423
Ensembl chrNW_004624764:6,221,867...6,318,477
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Ect2
epithelial cell transforming 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:50,773,465...50,841,427
Ensembl chrNW_004624730:50,773,566...50,840,510
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Edn1
endothelin 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:12609069
NCBI chrNW_004624756:13,842,482...13,849,003
Ensembl chrNW_004624756:13,842,164...13,849,029
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Eeig2
EEIG family member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624772:4,374,343...4,464,425
Ensembl chrNW_004624772:4,374,340...4,441,840
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Eif4e3
eukaryotic translation initiation factor 4E family member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624773:6,047,763...6,264,641
Ensembl chrNW_004624773:6,219,199...6,267,512
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Elovl5
ELOVL fatty acid elongase 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624850:523,059...598,135
Ensembl chrNW_004624850:522,018...597,469
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Emb
embigin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624759:9,085,231...9,157,643
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Emp1
epithelial membrane protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:24,778,610...24,797,395
Ensembl chrNW_004624752:24,780,689...24,797,544
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Enc1
ectodermal-neural cortex 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624924:281,251...294,248
Ensembl chrNW_004624924:281,327...294,248
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Enpep
glutamyl aminopeptidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624838:4,742,841...4,826,767
Ensembl chrNW_004624838:4,742,794...4,828,724
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Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
treatment
ISO
protein:increased activity:serum: CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:17072980 PMID:17850827 PMID:20957682
RGD:9685426 RGD:9685427
NCBI chrNW_004624763:17,677,825...17,775,284
Ensembl chrNW_004624763:17,677,722...17,765,292
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Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
ISO
RGD
PMID:15651265
RGD:9685530
NCBI chrNW_004624760:859,598...865,194
Ensembl chrNW_004624760:859,637...866,804
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Epb41l2
erythrocyte membrane protein band 4.1 like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624753:5,023,970...5,240,063
Ensembl chrNW_004624753:5,023,970...5,146,595
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Epcam
epithelial cell adhesion molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624738:28,755,039...28,770,160
Ensembl chrNW_004624738:28,754,602...28,770,758
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Erap1
endoplasmic reticulum aminopeptidase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624743:15,407,217...15,442,610
Ensembl chrNW_004624743:15,408,485...15,431,967
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Ern1
endoplasmic reticulum to nucleus signaling 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30538632
NCBI chrNW_004624849:1,521,996...1,625,878
Ensembl chrNW_004624849:1,525,235...1,625,893
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Extl1
exostosin like glycosyltransferase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624764:10,094,378...10,110,226
Ensembl chrNW_004624764:10,096,136...10,109,128
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Ezr
ezrin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624929:827,275...873,743
Ensembl chrNW_004624929:826,531...873,572
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F2r
coagulation factor II thrombin receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624869:1,181,288...1,200,751
Ensembl chrNW_004624869:1,181,354...1,200,664
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F5
coagulation factor V
treatment
ISO
RGD
PMID:17431769
RGD:7394781
NCBI chrNW_004624826:7,438,632...7,507,322
Ensembl chrNW_004624826:7,438,682...7,507,012
G
Fabp7
fatty acid binding protein 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624798:8,426,819...8,430,949
Ensembl chrNW_004624798:8,426,825...8,430,939
G
Fahd1
fumarylacetoacetate hydrolase domain containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624913:432,780...434,359
G
Fam167b
family with sequence similarity 167 member B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624764:15,463,521...15,470,683
Ensembl chrNW_004624764:15,461,947...15,471,372
G
Fam43a
family with sequence similarity 43 member A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:63,205,027...63,208,444
Ensembl chrNW_004624730:63,205,990...63,207,267
G
Fam89a
family with sequence similarity 89 member A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624775:18,611,986...18,629,798
Ensembl chrNW_004624775:18,611,999...18,629,798
G
Fas
Fas cell surface death receptor
ISO
mRNA, protein:increased expression:liver CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:17105443 PMID:30737368
RGD:2290284
NCBI chrNW_004624791:15,290,022...15,315,848
Ensembl chrNW_004624791:15,289,348...15,315,848
G
Fat1
FAT atypical cadherin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624769:17,801,796...17,924,685
Ensembl chrNW_004624769:17,801,894...17,925,191
G
Fbn1
fibrillin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624731:11,086,240...11,318,111
Ensembl chrNW_004624731:11,086,844...11,318,102
G
Fbxo9
F-box protein 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624850:287,585...335,939
Ensembl chrNW_004624850:287,586...336,827
G
Fcer1g
Fc fragment of IgE receptor Ig
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034
G
Fcgr3a
Fc fragment of IgG receptor IIIa
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624826:51,387...59,117
G
Fcn1
ficolin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:2,743,996...2,751,116
Ensembl chrNW_004624760:2,743,996...2,751,110
G
Fgf2
fibroblast growth factor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16116963
NCBI chrNW_004624777:3,268,674...3,321,424
Ensembl chrNW_004624777:3,268,953...3,321,145
G
Fgfr1
fibroblast growth factor receptor 1
treatment
ISO
RGD
PMID:21543745
RGD:25440477
NCBI chrNW_004624780:5,161,245...5,212,641
Ensembl chrNW_004624780:5,161,073...5,213,870
G
Fgg
fibrinogen gamma chain
ISO
mRNA:increased expression
RGD
PMID:17054587
RGD:1599810
NCBI chrNW_004624858:5,828,334...5,836,382
Ensembl chrNW_004624858:5,827,316...5,838,170
G
Fgl2
fibrinogen like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624739:26,501,149...26,507,305
Ensembl chrNW_004624739:26,503,965...26,507,305
G
Fgr
FGR proto-oncogene, Src family tyrosine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624764:11,482,719...11,513,215
Ensembl chrNW_004624764:11,489,685...11,513,270
G
Fhl1
four and a half LIM domains 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624808:10,924,606...10,984,422
Ensembl chrNW_004624808:10,924,248...10,965,164
G
Fhl2
four and a half LIM domains 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624749:9,453,081...9,507,050
Ensembl chrNW_004624749:9,453,088...9,483,009
G
Fkbp1a
FKBP prolyl isomerase 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624741:2,669,909...2,692,959
Ensembl chrNW_004624741:2,666,636...2,692,938
G
Fli1
Fli-1 proto-oncogene, ETS transcription factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624812:3,004,631...3,138,901
Ensembl chrNW_004624812:3,004,628...3,139,101
G
Flna
filamin A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624946:812,278...836,307
Ensembl chrNW_004624946:812,287...837,273
G
Fmnl1
formin like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624795:216,328...249,903
Ensembl chrNW_004624795:216,551...233,127
G
Fmnl2
formin like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624866:4,434,956...4,738,599
Ensembl chrNW_004624866:4,436,967...4,738,979
G
Fmo1
flavin containing dimethylaniline monoxygenase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624771:10,358,422...10,386,015
Ensembl chrNW_004624771:10,357,210...10,386,005
G
Fn1
fibronectin 1
treatment
ISO
mRNA:increased expression:liver: mRNA:altered expression:liver (rat)
RGD
PMID:15980055 PMID:19914391
RGD:1625201 RGD:4140452
NCBI chrNW_004624765:707,872...775,056
Ensembl chrNW_004624765:707,755...775,056
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:26,424,053...26,427,431
Ensembl chrNW_004624734:26,423,079...26,427,732
G
Foxa2
forkhead box A2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624741:22,645,580...22,649,722
Ensembl chrNW_004624741:22,645,519...22,649,854
G
Foxo1
forkhead box O1
ISO
associated with Schistosomiasis Japonica; mRNA:decreased expression:liver (rat)
RGD
PMID:29323718
RGD:38599216
NCBI chrNW_004624748:1,413,754...1,529,646
Ensembl chrNW_004624748:1,413,983...1,529,992
G
Fry
FRY microtubule binding protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624776:5,608,660...6,109,314
Ensembl chrNW_004624776:5,608,686...5,916,339
G
Fstl1
follistatin like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624731:27,789,671...27,839,267
Ensembl chrNW_004624731:27,790,363...27,841,251
G
Ftcd
formimidoyltransferase cyclodeaminase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624745:31,279,868...31,288,600
Ensembl chrNW_004624745:31,276,314...31,289,063
G
Fxyd2
FXYD domain containing ion transport regulator 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624784:13,198,308...13,209,780
Ensembl chrNW_004624784:13,200,018...13,206,131
G
Fxyd5
FXYD domain containing ion transport regulator 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624794:8,347,925...8,359,215
G
Fxyd6
FXYD domain containing ion transport regulator 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624784:13,213,579...13,252,710
Ensembl chrNW_004624784:13,213,457...13,253,400
G
Fyn
FYN proto-oncogene, Src family tyrosine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624933:248,298...456,933
Ensembl chrNW_004624933:389,627...456,520
G
Fzd8
frizzled class receptor 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624805:9,978,845...9,981,475
Ensembl chrNW_004624805:9,978,880...9,980,899
G
G0s2
G0/G1 switch 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624807:2,317,557...2,318,951
G
G6pc1
glucose-6-phosphatase catalytic subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624795:1,331,592...1,339,575
Ensembl chrNW_004624795:1,331,601...1,339,580
G
Gab1
GRB2 associated binding protein 1
ISO
protein:increased tyrosine phosphorylation: :
RGD
PMID:25617348
RGD:14995329
NCBI chrNW_004624853:2,639,882...2,763,195
Ensembl chrNW_004624853:2,639,891...2,765,144
G
Galc
galactosylceramidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:14,355,349...14,462,869
Ensembl chrNW_004624734:14,355,435...14,407,087
G
Gask1b
golgi associated kinase 1B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624848:420,751...463,903
G
Gc
GC vitamin D binding protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624890:3,274,239...3,318,281
Ensembl chrNW_004624890:3,226,900...3,318,316
G
Gcat
glycine C-acetyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:10,095,979...10,103,442
Ensembl chrNW_004624752:10,089,827...10,103,515
G
Gchfr
GTP cyclohydrolase I feedback regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624804:8,013,735...8,016,744
Ensembl chrNW_004624804:8,012,346...8,016,755
G
Gck
glucokinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624740:7,844,496...7,885,900
Ensembl chrNW_004624740:7,852,390...7,886,758
G
Gcnt1
glucosaminyl (N-acetyl) transferase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624811:3,930,673...3,973,755
Ensembl chrNW_004624811:3,930,973...3,970,908
G
Get1
guided entry of tail-anchored proteins factor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624745:24,625,206...24,635,129
Ensembl chrNW_004624745:24,627,526...24,635,159
G
Gfap
glial fibrillary acidic protein
ISO
associated with Schistosomiasis Japonica; mRNA:decreased expression:liver (rat)
RGD
PMID:29323718
RGD:38599216
NCBI chrNW_004624795:395,298...400,781
Ensembl chrNW_004624795:394,436...401,231
G
Gfra1
GDNF family receptor alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:30,325,962...30,526,311
Ensembl chrNW_004624737:30,324,515...30,526,486
G
Ggh
gamma-glutamyl hydrolase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624744:28,752,785...28,786,293
Ensembl chrNW_004624744:28,752,909...28,785,661
G
Ghr
growth hormone receptor
ISO
mRNA, protein:decreased expression:liver CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:12679928 PMID:17072980 PMID:25380136
RGD:2307378
NCBI chrNW_004624759:12,282,295...12,570,106
Ensembl chrNW_004624759:12,285,594...12,570,906
G
Gja1
gap junction protein alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624798:9,358,996...9,364,413
Ensembl chrNW_004624798:9,359,004...9,364,313
G
Gja4
gap junction protein alpha 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624764:17,842,566...17,845,011
Ensembl chrNW_004624764:17,836,180...17,845,011
G
Gk
glycerol kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624762:25,268,398...25,357,165
Ensembl chrNW_004624762:25,270,270...25,357,167
G
Glipr1
GLI pathogenesis related 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624750:22,556,443...22,610,963
Ensembl chrNW_004624750:22,556,713...22,573,699
G
Gls
glutaminase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624854:5,106,419...5,202,445
Ensembl chrNW_004624854:5,108,566...5,202,240
G
Gls2
glutaminase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624802:11,545,196...11,559,851
Ensembl chrNW_004624802:11,545,142...11,561,942
G
Glt8d1
glycosyltransferase 8 domain containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624822:4,506,275...4,520,151
Ensembl chrNW_004624822:4,506,395...4,521,704
G
Gmfg
glia maturation factor gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624794:12,668,720...12,676,471
Ensembl chrNW_004624794:12,668,618...12,676,502
G
Gna14
G protein subunit alpha 14
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624811:4,904,428...5,108,713
Ensembl chrNW_004624811:4,909,324...5,108,322
G
Gnai2
G protein subunit alpha i2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:4,096,061...4,126,538
Ensembl chrNW_004624730:4,103,905...4,126,737
G
Gngt2
G protein subunit gamma transducin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624795:5,444,274...5,448,464
Ensembl chrNW_004624795:5,444,334...5,448,441
G
Gnpda1
glucosamine-6-phosphate deaminase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624774:1,222,451...1,235,897
Ensembl chrNW_004624774:1,222,458...1,235,842
G
Got1
glutamic-oxaloacetic transaminase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624737:11,114,818...11,153,209
Ensembl chrNW_004624737:11,115,066...11,153,211
G
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:34,198,773...34,268,815
Ensembl chrNW_004624737:34,198,518...34,265,192
G
Gpnmb
glycoprotein nmb
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624739:7,358,824...7,386,852
Ensembl chrNW_004624739:7,359,741...7,387,279
G
Gpr68
G protein-coupled receptor 68
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:11,338,233...11,370,239
Ensembl chrNW_004624734:11,360,053...11,368,757
G
Gpt
glutamic--pyruvic transaminase
treatment
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:17072980 PMID:22706148
RGD:8552768
NCBI chrNW_004624735:12,355,476...12,359,910
Ensembl chrNW_004624735:12,355,476...12,360,028
G
Gpx8
glutathione peroxidase 8 (putative)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624759:4,119,203...4,123,757
Ensembl chrNW_004624759:4,117,102...4,123,877
G
Grk2
G protein-coupled receptor kinase 2
ISO
protein:increased expression:aorta
RGD
PMID:17256744
RGD:1625784
NCBI chrNW_004624767:19,212,218...19,231,218
Ensembl chrNW_004624767:19,210,965...19,231,082
G
Grn
granulin precursor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624795:704,066...708,721
Ensembl chrNW_004624795:704,252...707,165
G
Gsn
gelsolin
ISO
CTD Direct Evidence: marker/mechanism mRNA, protein:increased expression
CTD RGD
PMID:14574581 PMID:25380136
RGD:1599866
NCBI chrNW_004624760:13,943,680...14,004,660
Ensembl chrNW_004624760:13,943,888...13,969,905
G
Gsta4
glutathione S-transferase alpha 4
treatment
ISO
RGD
PMID:23075396
RGD:9685568
NCBI chrNW_004624850:201,119...217,302
Ensembl chrNW_004624850:201,592...216,680
G
Gulp1
GULP PTB domain containing engulfment adaptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624899:1,581,299...1,844,391
Ensembl chrNW_004624899:1,581,309...1,679,498
G
Gzma
granzyme A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624759:4,177,857...4,185,325
Ensembl chrNW_004624759:4,177,857...4,185,324
G
Hagh
hydroxyacylglutathione hydrolase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624913:426,554...446,061
Ensembl chrNW_004624913:434,537...446,061
G
Hal
histidine ammonia-lyase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624750:11,318,572...11,344,326
Ensembl chrNW_004624750:11,318,511...11,343,459
G
Hao1
hydroxyacid oxidase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624741:8,762,556...8,824,517
Ensembl chrNW_004624741:8,763,496...8,824,468
G
Hao2
hydroxyacid oxidase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624772:14,981,777...15,022,699
Ensembl chrNW_004624772:14,981,666...15,023,173
G
Hck
HCK proto-oncogene, Src family tyrosine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624741:456,186...494,207
Ensembl chrNW_004624741:455,696...493,821
G
Hells
helicase, lymphoid specific
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:5,892,705...5,954,364
G
Hexim1
HEXIM P-TEFb complex subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624795:257,553...260,685
G
Hgf
hepatocyte growth factor
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:10677585 PMID:12918455 PMID:15793283 PMID:16465399 PMID:16627068 PMID:17714472 PMID:18637143 More...
NCBI chrNW_004624739:30,233,589...30,307,508
Ensembl chrNW_004624739:30,236,146...30,307,356
G
Hip1
huntingtin interacting protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624740:14,460,742...14,607,203
Ensembl chrNW_004624740:14,464,372...14,607,130
G
Hjv
hemojuvelin BMP co-receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624772:17,363,062...17,367,320
Ensembl chrNW_004624772:17,360,207...17,367,373
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624951:681,559...711,476
Ensembl chrNW_004624951:682,178...711,474
G
Hmox1
heme oxygenase 1
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
RGD CTD
PMID:16025519 PMID:16610050 PMID:19554654 PMID:21163135 PMID:25380136
RGD:4145305
NCBI chrNW_004624750:341,699...346,005
Ensembl chrNW_004624750:342,146...345,887
G
Hopx
HOP homeobox
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624761:12,776,215...12,806,879
Ensembl chrNW_004624761:12,776,137...12,807,042
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Hoxa3
homeobox A3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624739:3,453,358...3,498,061
Ensembl chrNW_004624739:3,478,406...3,498,333
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Hpcal1
hippocalcin like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624865:4,862,653...4,921,687
Ensembl chrNW_004624865:4,862,547...4,908,135
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Hpgds
hematopoietic prostaglandin D synthase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624757:22,114,917...22,166,833
Ensembl chrNW_004624757:22,114,249...22,140,059
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Hpse
heparanase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15095483 PMID:18458672
NCBI chrNW_004624900:296,626...335,624
Ensembl chrNW_004624900:296,676...335,570
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Hsd17b2
hydroxysteroid 17-beta dehydrogenase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624746:5,372,176...5,445,726
Ensembl chrNW_004624746:5,368,142...5,446,429
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Hsd17b6
hydroxysteroid 17-beta dehydrogenase 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624802:11,125,544...11,162,914
Ensembl chrNW_004624802:11,115,928...11,162,174
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Htr2b
5-hydroxytryptamine receptor 2B
ISO
protein:increased expression:liver (rat)
RGD
PMID:16936262
RGD:9743846
NCBI chrNW_004624843:4,407,055...4,424,585
Ensembl chrNW_004624843:4,408,424...4,424,168
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Hykk
hydroxylysine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624894:2,423,304...2,444,401
Ensembl chrNW_004624894:2,422,895...2,444,654
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Id2
inhibitor of DNA binding 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17127702
NCBI chrNW_004624846:2,281,292...2,283,596
Ensembl chrNW_004624846:2,277,961...2,283,571
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Id4
inhibitor of DNA binding 4, HLH protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624756:6,816,364...6,819,144
Ensembl chrNW_004624756:6,814,842...6,819,578
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Ido1
indoleamine 2,3-dioxygenase 1
severity
ISO
protein:increased expression:serum (mouse)
RGD
PMID:28465467
RGD:39939037
NCBI chrNW_004624780:3,684,941...3,697,506
Ensembl chrNW_004624780:3,685,069...3,697,474
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Idua
alpha-L-iduronidase
ISO
protein:increased expression:liver
RGD
PMID:6875476
RGD:12910840
NCBI chrNW_004624755:26,151,302...26,169,324
Ensembl chrNW_004624755:26,154,186...26,169,365
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Ifi35
interferon induced protein 35
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624795:1,260,476...1,268,015
Ensembl chrNW_004624795:1,260,476...1,262,080
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Ifng
interferon gamma
ISO
CTD Direct Evidence: therapeutic protein:increased expression:serum (mouse)
CTD RGD
PMID:12389079 PMID:15996030 PMID:16953842 PMID:17347453 PMID:28465467
RGD:39939037
NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534
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Ifngr1
interferon gamma receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624886:618,372...640,954
Ensembl chrNW_004624886:618,289...642,928
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Ifrd1
interferon related developmental regulator 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624739:17,442,191...17,492,191
Ensembl chrNW_004624739:17,442,191...17,466,909
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Igf1
insulin like growth factor 1
treatment
ISO
protein:increased expression:liver: CTD Direct Evidence: therapeutic
RGD CTD
PMID:12800242 PMID:15591519 PMID:15745444 PMID:16434425 PMID:20198635
RGD:10045984 RGD:12904923 RGD:2317647
NCBI chrNW_004624750:5,881,065...5,954,799
Ensembl chrNW_004624750:5,881,091...5,952,300
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Igf1r
insulin like growth factor 1 receptor
ISO
protein:increased expression:liver:
RGD
PMID:12800242
RGD:10045984
NCBI chrNW_004624768:5,396,027...5,688,435
Ensembl chrNW_004624768:5,396,156...5,681,809
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Igf2bp3
insulin like growth factor 2 mRNA binding protein 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624739:7,154,893...7,319,724
Ensembl chrNW_004624739:7,158,020...7,319,720
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Igf2r
insulin like growth factor 2 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624855:2,752,676...2,887,327
Ensembl chrNW_004624855:2,753,994...2,887,151
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Igfals
insulin like growth factor binding protein acid labile subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624913:460,862...464,457
Ensembl chrNW_004624913:458,844...465,193
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Igfbp1
insulin like growth factor binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624740:6,893,334...6,897,591
Ensembl chrNW_004624740:6,893,867...6,897,377
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Igfbp2
insulin like growth factor binding protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624823:8,460,968...8,486,495
Ensembl chrNW_004624823:8,460,553...8,486,495
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Igfbp3
insulin like growth factor binding protein 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624740:6,878,818...6,886,512
Ensembl chrNW_004624740:6,877,348...6,886,512
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Igfbp7
insulin like growth factor binding protein 7
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:25380136 PMID:25691930
RGD:401976485
NCBI chrNW_004624761:12,318,571...12,387,489
Ensembl chrNW_004624761:12,318,006...12,387,582
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Igsf6
immunoglobulin superfamily member 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624782:7,820,478...7,834,467
Ensembl chrNW_004624782:7,824,593...7,834,419
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Ikbkg
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30737368
NCBI chrNW_004624946:997,571...1,015,748
Ensembl chrNW_004624946:996,814...1,013,379
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Il10
interleukin 10
treatment
ISO
CTD Direct Evidence: therapeutic
RGD CTD
PMID:12632514 PMID:15362042 PMID:16097045 PMID:16126171 PMID:16539848 PMID:16552806 PMID:16609999 PMID:16688825 PMID:18251166 PMID:23980370 PMID:24993843 More...
RGD:11049490 RGD:7364982
NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732
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Il17a
interleukin 17A
treatment
ISO
protein:increased expression:liver, serum (mouse)
RGD
PMID:28465467 PMID:30346985
RGD:151665755 RGD:39939037
NCBI chrNW_004624855:3,911,349...3,914,214
Ensembl chrNW_004624855:3,911,349...3,913,136
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Il17ra
interleukin 17 receptor A
treatment
ISO
RGD
PMID:30346985
RGD:151665755
NCBI chrNW_004624735:10,139,787...10,164,074
Ensembl chrNW_004624735:10,138,418...10,164,198
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Il17rc
interleukin 17 receptor C
treatment
ISO
RGD
PMID:30346985
RGD:151665755
NCBI chrNW_004624731:4,524,090...4,536,879
Ensembl chrNW_004624731:4,525,556...4,536,858
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Il18
interleukin 18
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624784:7,294,286...7,312,959
Ensembl chrNW_004624784:7,294,183...7,304,687
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Il18bp
interleukin 18 binding protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624817:4,963,586...4,967,122
Ensembl chrNW_004624817:4,964,403...4,965,944
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Il1b
interleukin 1 beta
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16085334 PMID:24383550
RGD:10450610
NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760
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Il2
interleukin 2
treatment
ISO
RGD
PMID:30346985
RGD:151665755
NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453
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Il2rb
interleukin 2 receptor subunit beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:10,662,053...10,682,891
Ensembl chrNW_004624752:10,672,432...10,683,045
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Il2rg
interleukin 2 receptor subunit gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624903:1,402,586...1,406,554
Ensembl chrNW_004624903:1,402,481...1,406,600
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Il33
interleukin 33
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624736:10,733,944...10,786,188
Ensembl chrNW_004624736:10,764,486...10,784,864
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Il4
interleukin 4
ISO
protein:decreased expression:serum (mouse)
RGD
PMID:28465467
RGD:39939037
NCBI chrNW_004624733:39,412,800...39,420,079
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Il6
interleukin 6
treatment
ISO
mRNA:increased expression:liver (mouse)
RGD
PMID:24383550 PMID:28465467 PMID:30346985
RGD:10450610 RGD:151665755 RGD:39939037
NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318
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Il7r
interleukin 7 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624759:19,067,933...19,103,007
Ensembl chrNW_004624759:19,067,856...19,098,859
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Ilk
integrin linked kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16941698
NCBI chrNW_004624817:8,096,539...8,103,096
Ensembl chrNW_004624817:8,096,898...8,106,683
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Inhbc
inhibin subunit beta C
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624802:10,503,431...10,517,383
Ensembl chrNW_004624802:10,501,502...10,518,188
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Inhbe
inhibin subunit beta E
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624802:10,497,618...10,499,433
Ensembl chrNW_004624802:10,493,576...10,499,565
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Inmt
indolethylamine N-methyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624783:17,712...22,867
Ensembl chrNW_004624783:17,084...20,921
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Inpp5d
inositol polyphosphate-5-phosphatase D
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624843:5,685,409...5,774,459
Ensembl chrNW_004624843:5,685,502...5,773,469
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Inppl1
inositol polyphosphate phosphatase like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624817:4,779,875...4,794,644
Ensembl chrNW_004624817:4,779,057...4,793,732
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Ins
insulin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:26806094
NCBI chrNW_004624767:14,999,088...15,000,035
Ensembl chrNW_004624767:14,999,088...15,000,035
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Insig2
insulin induced gene 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624732:27,089,776...27,110,170
Ensembl chrNW_004624732:27,087,674...27,104,181
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Iqgap1
IQ motif containing GTPase activating protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624768:17,703,113...17,797,922
Ensembl chrNW_004624768:17,702,728...17,799,022
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Irf8
interferon regulatory factor 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624746:2,272,385...2,290,400
Ensembl chrNW_004624746:2,272,389...2,290,455
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Isg20
interferon stimulated exonuclease gene 20
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624768:15,949,591...15,958,816
Ensembl chrNW_004624768:15,949,470...15,960,653
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Isyna1
inositol-3-phosphate synthase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624908:1,658,512...1,661,507
Ensembl chrNW_004624908:1,658,512...1,661,640
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Itga2b
integrin subunit alpha 2b
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624795:683,899...695,262
Ensembl chrNW_004624795:683,968...703,710
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Itgal
integrin subunit alpha L
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624782:13,635,217...13,671,401
Ensembl chrNW_004624782:13,640,996...13,669,541
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Itgb1
integrin subunit beta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624805:8,748,848...8,800,259
Ensembl chrNW_004624805:8,765,949...8,802,149
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Itgb2
integrin subunit beta 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624745:30,452,576...30,479,036
Ensembl chrNW_004624745:30,452,576...30,470,611
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Itgb3
integrin subunit beta 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624849:1,895,378...1,952,755
Ensembl chrNW_004624849:1,895,914...1,952,665
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Itgb6
integrin subunit beta 6
ISO
mRNA, protein:increased expression:liver CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:18221819 PMID:18538673
RGD:2302244
NCBI chrNW_004624732:5,348,589...5,499,826
Ensembl chrNW_004624732:5,403,956...5,499,855
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Iyd
iodotyrosine deiodinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624785:7,799,975...7,824,611
Ensembl chrNW_004624785:7,800,408...7,824,647
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Jak2
Janus kinase 2
ISO
protein:increased expression, increased tyrosine phosphorylation:liver CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:24619965 PMID:25380136
RGD:10403061
NCBI chrNW_004624736:9,724,876...9,827,364
Ensembl chrNW_004624736:9,724,369...9,830,365
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Jdp2
Jun dimerization protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:26,228,147...26,276,485
Ensembl chrNW_004624734:26,224,961...26,276,612
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Kank1
KN motif and ankyrin repeat domains 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624736:5,260,761...5,444,234
Ensembl chrNW_004624736:5,379,728...5,444,234
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Kcnj8
potassium inwardly rectifying channel subfamily J member 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:16,939,289...16,945,692
Ensembl chrNW_004624752:16,939,384...16,946,723
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Kcnn4
potassium calcium-activated channel subfamily N member 4
exacerbates
ISO
mRNA:increased expression:liver (rat)
RGD
PMID:27354175
RGD:329955558
NCBI chrNW_004624907:1,266,348...1,279,258
Ensembl chrNW_004624907:1,266,348...1,278,699
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Klf6
KLF transcription factor 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624796:1,531,934...1,539,728
Ensembl chrNW_004624796:1,531,910...1,539,970
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Kmo
kynurenine 3-monooxygenase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624771:11,900,020...11,942,943
Ensembl chrNW_004624771:11,899,624...11,942,806
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Kng1
kininogen 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:18054572
NCBI chrNW_004624730:70,022,449...70,065,115
G
Krt18
keratin 18
ISO
CTD Direct Evidence: marker/mechanism protein:increased expression:liver, plasma membrane (rat)
CTD RGD
PMID:15999547 PMID:17072980 PMID:18395095 PMID:21138630 PMID:25380136
RGD:27226809
NCBI chrNW_004624904:1,011,675...1,015,319
Ensembl chrNW_004624904:1,011,755...1,015,416
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Krt8
keratin 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624904:970,136...978,211
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Ktn1
kinectin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624884:365,312...484,007
Ensembl chrNW_004624884:409,339...483,562
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Kynu
kynureninase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624732:42,627,789...42,751,037
Ensembl chrNW_004624732:42,627,715...42,753,165
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L3hypdh
trans-L-3-hydroxyproline dehydratase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:41,625,899...41,636,907
Ensembl chrNW_004624734:41,625,812...41,634,884
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Laptm5
lysosomal protein transmembrane 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624764:14,208,144...14,277,208
Ensembl chrNW_004624764:14,207,094...14,228,135
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Lbh
LBH regulator of WNT signaling pathway
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624738:12,098,227...12,129,968
Ensembl chrNW_004624738:12,106,236...12,130,052
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Lbp
lipopolysaccharide binding protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624842:1,306,299...1,332,269
Ensembl chrNW_004624842:1,301,831...1,332,346
G
Lcp1
lymphocyte cytosolic protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624748:8,740,563...8,833,091
Ensembl chrNW_004624748:8,779,395...8,835,500
G
Lcp2
lymphocyte cytosolic protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624733:19,625,276...19,720,125
Ensembl chrNW_004624733:19,672,868...19,719,584
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Ldhb
lactate dehydrogenase B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:17,046,640...17,065,910
Ensembl chrNW_004624752:17,049,296...17,069,553
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Lefty2
left-right determination factor 2
ameliorates
ISO
RGD
PMID:34887753
RGD:401794438
NCBI chrNW_004624807:71,011...75,210
G
Lep
leptin
disease_progression
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12586293 PMID:16097051 PMID:19065677 PMID:20509998 PMID:29248466
RGD:5128589 RGD:5128713
NCBI chrNW_004624783:7,708,820...7,721,610
Ensembl chrNW_004624783:7,708,588...7,721,727
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Lepr
leptin receptor
ISO
protein:increased expression:serum
RGD
PMID:23886859
RGD:10412036
NCBI chrNW_004624742:29,221,742...29,313,273
Ensembl chrNW_004624742:29,223,392...29,337,049
G
Lgals1
galectin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:10,220,115...10,223,434
Ensembl chrNW_004624752:10,219,872...10,223,317
G
Lgals2
galectin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:10,315,705...10,321,253
Ensembl chrNW_004624752:10,319,011...10,321,069
G
Lgals3
galectin 3
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:12646584 PMID:16549783 PMID:25380136
RGD:9685223 RGD:9685224
NCBI chrNW_004624731:14,300,138...14,307,843
Ensembl chrNW_004624731:14,298,201...14,304,637
G
Lgalsl
galectin like
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624762:9,033,266...9,040,443
Ensembl chrNW_004624762:9,032,875...9,040,966
G
Lgmn
legumain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:9,207,496...9,240,026
Ensembl chrNW_004624734:9,204,790...9,240,309
G
Lhfpl6
LHFPL tetraspan subfamily member 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624748:139,378...409,093
Ensembl chrNW_004624748:140,383...407,294
G
Limk2
LIM domain kinase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624747:7,700,996...7,766,713
Ensembl chrNW_004624747:7,700,411...7,766,713
G
Lin7a
lin-7 homolog A, crumbs cell polarity complex component
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624837:104,948...258,085
G
Lmo2
LIM domain only 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624767:13,245,783...13,257,322
Ensembl chrNW_004624767:13,245,984...13,257,440
G
LOC101699044
cytochrome P450 26A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:4,324,964...4,329,488
Ensembl chrNW_004624737:4,325,755...4,329,758
G
LOC101700274
HLA class II histocompatibility antigen, DM alpha chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:23,752,352...23,765,319
Ensembl chrNW_004624754:23,762,051...23,765,593
G
LOC101701356
HLA class II histocompatibility antigen, DM beta chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:23,774,013...23,779,851
Ensembl chrNW_004624754:23,773,934...23,779,952
G
LOC101701685
cholesterol 7-alpha-monooxygenase
treatment
ISO
RGD
PMID:15521018
RGD:15045602
NCBI chrNW_004624744:33,563,564...33,619,851
Ensembl chrNW_004624744:33,612,901...33,619,869
G
LOC101706353
HLA class II histocompatibility antigen, DR alpha chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:24,079,459...24,086,342
Ensembl chrNW_004624754:24,079,366...24,084,512
G
LOC101709509
cytochrome b-245 heavy chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624762:17,759,625...17,793,434
Ensembl chrNW_004624762:17,757,404...17,793,467
G
LOC101717043
cytochrome b-245 light chain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624746:911,852...919,361
Ensembl chrNW_004624746:911,842...919,362
G
LOC101719398
serotransferrin
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:15650968 PMID:22464783
RGD:7244387
NCBI chrNW_004624730:10,078,165...10,109,349
G
LOC101721569
folate receptor gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
G
LOC101726496
steroid 17-alpha-hydroxylase/17,20 lyase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624831:2,155,851...2,166,621
Ensembl chrNW_004624831:2,157,048...2,166,539
G
Lox
lysyl oxidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624774:20,116,625...20,137,767
Ensembl chrNW_004624774:20,116,970...20,134,355
G
Loxl2
lysyl oxidase like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624758:18,567,367...18,644,528
Ensembl chrNW_004624758:18,568,607...18,621,785
G
Lpl
lipoprotein lipase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624758:15,652,553...15,680,107
Ensembl chrNW_004624758:15,651,992...15,680,762
G
Lpxn
leupaxin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624864:1,815,056...1,852,041
Ensembl chrNW_004624864:1,818,614...1,852,503
G
Lrat
lecithin retinol acyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624853:2,936,426...2,941,993
Ensembl chrNW_004624853:2,936,109...2,945,101
G
Lrp6
LDL receptor related protein 6
ISO
RGD
PMID:18006602
RGD:4110127
NCBI chrNW_004624752:25,605,444...25,756,573
Ensembl chrNW_004624752:25,605,302...25,751,893
G
Lrrc28
leucine rich repeat containing 28
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624768:4,984,515...5,105,162
Ensembl chrNW_004624768:4,982,020...5,105,019
G
Lrrfip1
LRR binding FLII interacting protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624847:2,993,251...3,095,611
Ensembl chrNW_004624847:2,993,291...3,094,961
G
Lta4h
leukotriene A4 hydrolase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624750:11,274,506...11,314,683
Ensembl chrNW_004624750:11,274,664...11,314,581
G
Ltb
lymphotoxin beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:24,618,888...24,620,448
G
Ltbp1
latent transforming growth factor beta binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624738:14,602,790...15,035,610
Ensembl chrNW_004624738:14,602,805...15,034,805
G
Lum
lumican
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624750:15,553,400...15,560,746
Ensembl chrNW_004624750:15,553,383...15,559,408
G
Lurap1l
leucine rich adaptor protein 1 like
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624736:17,091,115...17,137,503
Ensembl chrNW_004624736:17,091,198...17,141,023
G
Ly86
lymphocyte antigen 86
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624756:18,770,503...18,821,191
Ensembl chrNW_004624756:18,770,503...18,820,672
G
Ly96
lymphocyte antigen 96
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624744:17,209,285...17,241,347
Ensembl chrNW_004624744:17,208,990...17,241,347
G
Magee1
MAGE family member E1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624836:4,420,633...4,423,996
Ensembl chrNW_004624836:4,420,509...4,424,039
G
Map1lc3a
microtubule associated protein 1 light chain 3 alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624842:4,800,533...4,802,235
Ensembl chrNW_004624842:4,800,539...4,802,094
G
Map3k8
mitogen-activated protein kinase kinase kinase 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624805:2,611,297...2,633,650
Ensembl chrNW_004624805:2,611,038...2,633,943
G
Mapk1
mitogen-activated protein kinase 1
treatment
ISO
RGD
PMID:27396351
RGD:13800880
NCBI chrNW_004624747:1,296,062...1,389,674
Ensembl chrNW_004624747:1,296,221...1,389,757
G
Mapk3
mitogen-activated protein kinase 3
treatment
ISO
RGD
PMID:27396351
RGD:13800880
NCBI chrNW_004624782:13,150,824...13,158,327
Ensembl chrNW_004624782:13,152,039...13,159,113
G
Mas1
MAS1 proto-oncogene, G protein-coupled receptor
ISO
mRNA:increased expression:liver (rat)
RGD
PMID:19793108
RGD:2316776
NCBI chrNW_004624855:2,968,111...3,008,728
Ensembl chrNW_004624855:2,969,444...2,970,421
G
Mdh1
malate dehydrogenase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624762:9,884,521...9,900,593
Ensembl chrNW_004624762:9,881,950...9,901,372
G
Meox2
mesenchyme homeobox 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624739:14,483,750...14,547,491
Ensembl chrNW_004624739:14,483,789...14,547,374
G
Met
MET proto-oncogene, receptor tyrosine kinase
ISO
protein:decreased expression:liver (rat)
RGD
PMID:16958060
RGD:2317516
NCBI chrNW_004624827:2,589,157...2,724,065
Ensembl chrNW_004624827:2,587,966...2,723,995
G
Metrnl
meteorin like, glial cell differentiation regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624801:11,701,821...11,715,693
Ensembl chrNW_004624801:11,701,778...11,715,383
G
Mfap4
microfibril associated protein 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624849:5,661,916...5,665,290
Ensembl chrNW_004624849:5,661,920...5,664,970
G
Mfn2
mitofusin 2
treatment
ISO
mRNA, protein:decreased expression:liver (rat)
RGD
PMID:25369251 PMID:26882442
RGD:12910839 RGD:13204798
NCBI chrNW_004624818:1,041,371...1,065,061
Ensembl chrNW_004624818:1,041,369...1,065,023
G
Mgat5
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23798564
NCBI chrNW_004624732:33,564,740...33,896,573
Ensembl chrNW_004624732:33,605,569...33,898,834
G
Mgmt
O-6-methylguanine-DNA methyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:17,271,881...17,619,123
Ensembl chrNW_004624737:17,271,992...17,528,889
G
Mgp
matrix Gla protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:23,146,025...23,149,266
Ensembl chrNW_004624752:23,146,166...23,149,048
G
Mid1ip1
MID1 interacting protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624762:16,678,350...16,680,691
Ensembl chrNW_004624762:16,678,273...16,680,729
G
Mif
macrophage migration inhibitory factor
ISO
protein:increased expression:hepatocyte
RGD
PMID:14706927
RGD:1642000
NCBI chrNW_004624747:10,307,826...10,308,649
Ensembl chrNW_004624747:10,303,919...10,308,821
G
Mindy3
MINDY lysine 48 deubiquitinase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624796:11,778,932...11,862,882
Ensembl chrNW_004624796:11,778,201...11,863,318
G
Mis12
MIS12 kinetochore complex component
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624786:9,285,475...9,289,659
Ensembl chrNW_004624786:9,285,830...9,289,454
G
Mki67
marker of proliferation Ki-67
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:18,935,686...18,963,907
G
Mme
membrane metalloendopeptidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16085334
NCBI chrNW_004624730:32,601,835...32,691,368
Ensembl chrNW_004624730:32,601,488...32,689,080
G
Mmp1
matrix metallopeptidase 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:12557150
NCBI chrNW_004624878:71,642...79,660
Ensembl chrNW_004624878:71,642...79,602
G
Mmp13
matrix metallopeptidase 13
treatment
ISO
CTD Direct Evidence: therapeutic
CTD RGD
PMID:10623612 PMID:17404313
RGD:10043161
NCBI chrNW_004624918:2,228,688...2,239,852
G
Mmp15
matrix metallopeptidase 15
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624746:28,128,687...28,147,964
Ensembl chrNW_004624746:28,130,128...28,147,381
G
Mmp2
matrix metallopeptidase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15095483 PMID:25380136
NCBI chrNW_004624757:1,450,680...1,479,160
Ensembl chrNW_004624757:1,448,698...1,479,255
G
Mmp3
matrix metallopeptidase 3
ISO
RGD
PMID:17094476
RGD:2325929
NCBI chrNW_004624878:39,282...47,386
Ensembl chrNW_004624878:39,358...47,075
G
Mmp8
matrix metallopeptidase 8
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15057751
NCBI chrNW_004624878:124,396...174,584
Ensembl chrNW_004624878:164,171...175,654
G
Mmp9
matrix metallopeptidase 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15095483
NCBI chrNW_004624790:8,584,399...8,591,763
Ensembl chrNW_004624790:8,583,457...8,591,713
G
Mob3a
MOB kinase activator 3A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624828:6,755,018...6,771,614
Ensembl chrNW_004624828:6,755,059...6,771,961
G
Mro
maestro
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624778:14,352,071...14,359,861
Ensembl chrNW_004624778:14,352,856...14,359,678
G
Msn
moesin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624898:1,525,795...1,601,402
Ensembl chrNW_004624898:1,525,388...1,601,539
G
Mtmr7
myotubularin related protein 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624769:21,889,723...21,987,888
Ensembl chrNW_004624769:21,889,747...21,984,550
G
Mtor
mechanistic target of rapamycin kinase
treatment
ISO
RGD
PMID:25454463
RGD:10040998
NCBI chrNW_004624818:1,570,155...1,698,264
Ensembl chrNW_004624818:1,570,276...1,698,259
G
Mvp
major vault protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624782:13,363,121...13,386,961
Ensembl chrNW_004624782:13,363,000...13,387,086
G
Myadm
myeloid associated differentiation marker
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624832:2,568,128...2,574,248
Ensembl chrNW_004624832:2,568,128...2,573,544
G
Myc
MYC proto-oncogene, bHLH transcription factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624735:27,780,338...27,784,714
Ensembl chrNW_004624735:27,780,037...27,784,806
G
Myl9
myosin light chain 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624842:2,975,992...2,982,956
Ensembl chrNW_004624842:2,975,987...2,982,953
G
Myo1c
myosin IC
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624786:4,188,143...4,211,712
Ensembl chrNW_004624786:4,188,143...4,211,732
G
Myo1f
myosin IF
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624828:1,269,287...1,307,676
Ensembl chrNW_004624828:1,269,610...1,307,443
G
Myo5a
myosin VA
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624731:8,114,557...8,280,586
Ensembl chrNW_004624731:8,113,715...8,280,823
G
Myoc
myocilin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624771:10,066,170...10,080,257
Ensembl chrNW_004624771:10,065,788...10,080,680
G
Nagk
N-acetylglucosamine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624762:2,382,708...2,391,896
Ensembl chrNW_004624762:2,382,709...2,391,656
G
Nap1l5
nucleosome assembly protein 1 like 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624757:16,371,276...16,373,098
Ensembl chrNW_004624757:16,372,499...16,372,994
G
Nat8
N-acetyltransferase 8 (putative)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624762:96,735...97,440
G
Nbea
neurobeachin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624776:1,784,253...2,502,324
Ensembl chrNW_004624776:1,784,133...2,502,864
G
Nckap1l
NCK associated protein 1 like
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624904:2,508,576...2,575,505
Ensembl chrNW_004624904:2,508,799...2,578,609
G
Ncor2
nuclear receptor corepressor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624747:23,777,645...23,887,804
Ensembl chrNW_004624747:23,777,325...23,865,804
G
Ndrg1
N-myc downstream regulated 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624735:22,734,365...22,782,247
Ensembl chrNW_004624735:22,734,228...22,782,347
G
Ndrg2
NDRG family member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624825:7,008,475...7,017,422
Ensembl chrNW_004624825:7,008,475...7,017,676
G
Nectin2
nectin cell adhesion molecule 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624907:1,713,786...1,739,158
Ensembl chrNW_004624907:1,713,443...1,740,627
G
Nek6
NIMA related kinase 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:10,739,235...10,807,744
Ensembl chrNW_004624760:10,739,235...10,797,238
G
Nfe2l2
NFE2 like bZIP transcription factor 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:23341968
NCBI chrNW_004624787:14,355,330...14,381,353
Ensembl chrNW_004624787:14,355,791...14,381,251
G
Nfkbia
NFKB inhibitor alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26806094
NCBI chrNW_004624838:1,384,337...1,387,602
Ensembl chrNW_004624838:1,384,204...1,390,205
G
Nfkbie
NFKB inhibitor epsilon
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:15,593,755...15,605,998
Ensembl chrNW_004624754:15,593,765...15,605,788
G
Nfkbiz
NFKB inhibitor zeta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152
G
Nhsl3
NHS like 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624764:15,862,264...15,891,307
Ensembl chrNW_004624764:15,862,279...15,888,893
G
Nid1
nidogen 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624775:14,486,357...14,563,341
Ensembl chrNW_004624775:14,486,145...14,563,447
G
Nid2
nidogen 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624731:16,970,974...17,032,515
Ensembl chrNW_004624731:16,970,556...17,031,833
G
Nipal2
NIPA like domain containing 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624763:5,334,722...5,433,062
Ensembl chrNW_004624763:5,332,593...5,433,032
G
Nlrc5
NLR family CARD domain containing 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26806094
NCBI chrNW_004624746:28,954,009...29,030,337
Ensembl chrNW_004624746:28,954,016...29,030,322
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Nmi
N-myc and STAT interactor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624866:4,230,258...4,263,156
Ensembl chrNW_004624866:4,229,535...4,263,688
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Noct
nocturnin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624777:19,379,447...19,383,477
G
Nos2
nitric oxide synthase 2
ISO
mRNA:increased expression:heart CTD Direct Evidence: therapeutic mRNA:increased expression:aorta
RGD CTD
PMID:10353629 PMID:10784593 PMID:18380797
RGD:2325265 RGD:2325278
NCBI chrNW_004624786:491,944...530,427
Ensembl chrNW_004624786:489,311...528,271
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Nos3
nitric oxide synthase 3
ISO
CTD Direct Evidence: marker/mechanism protein:decreased expression:spleen protein:decreased expression:liver
CTD RGD
PMID:17481668 PMID:17918268 PMID:18555214
RGD:2292126 RGD:2292140
NCBI chrNW_004624800:5,600,215...5,619,020
Ensembl chrNW_004624800:5,600,212...5,619,004
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Nox4
NADPH oxidase 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624845:669,880...829,471
Ensembl chrNW_004624845:669,902...827,834
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Npas2
neuronal PAS domain protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624749:5,636,878...5,790,670
Ensembl chrNW_004624749:5,636,782...5,790,779
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Npdc1
neural proliferation, differentiation and control 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:866,358...871,572
Ensembl chrNW_004624760:866,570...871,305
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Nqo2
N-ribosyldihydronicotinamide:quinone dehydrogenase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624756:21,857,048...21,869,657
Ensembl chrNW_004624756:21,857,721...21,867,727
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Nr0b2
nuclear receptor subfamily 0 group B member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624764:10,896,728...10,899,898
Ensembl chrNW_004624764:10,892,481...10,899,215
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Nr1h4
nuclear receptor subfamily 1 group H member 4
treatment
ISO
mRNA:altered expression:liver (rat) associated with portal hypertension;mRNA;decreased expression;liver (rat)
RGD
PMID:15980055 PMID:24259407 PMID:27993716
RGD:14701034 RGD:15045598 RGD:1625201
NCBI chrNW_004624750:7,222,306...7,303,809
Ensembl chrNW_004624750:7,219,251...7,303,834
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Nrep
neuronal regeneration related protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624743:29,529,356...29,557,620
Ensembl chrNW_004624743:29,529,356...29,557,414
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Nrg1
neuregulin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624780:11,297,306...11,525,236
Ensembl chrNW_004624780:11,301,182...12,424,066
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Nrros
negative regulator of reactive oxygen species
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:61,717,592...61,742,374
Ensembl chrNW_004624730:61,735,134...61,742,541
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Nsmf
NMDA receptor synaptonuclear signaling and neuronal migration factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:575,805...583,410
Ensembl chrNW_004624760:574,920...583,410
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Nt5e
5'-nucleotidase ecto
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18263696
NCBI chrNW_004624799:8,766,608...8,845,296
Ensembl chrNW_004624799:8,765,711...8,845,778
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Nupr1
nuclear protein 1, transcriptional regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624782:13,042,938...13,044,298
Ensembl chrNW_004624782:13,042,939...13,044,267
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Oat
ornithine aminotransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:22,657,158...22,679,213
Ensembl chrNW_004624737:22,664,129...22,678,535
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Ogg1
8-oxoguanine DNA glycosylase
treatment
ISO
RGD
PMID:23053977
RGD:8657403
NCBI chrNW_004624731:4,383,000...4,388,486
Ensembl chrNW_004624731:4,383,434...4,388,196
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Olfml2b
olfactomedin like 2B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624826:440,584...477,986
Ensembl chrNW_004624826:440,026...478,037
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Olfml3
olfactomedin like 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624772:9,660,538...9,663,761
Ensembl chrNW_004624772:9,660,774...9,663,870
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Osgin1
oxidative stress induced growth inhibitor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624746:3,577,184...3,610,079
G
Osm
oncostatin M
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17640959
NCBI chrNW_004624747:6,580,717...6,584,695
G
Otc
ornithine transcarbamylase
ISO
CTD Direct Evidence: marker/mechanism protein:decreased activity:liver (rat)
CTD RGD
PMID:7865721 PMID:25380136
RGD:4144080
NCBI chrNW_004624762:17,038,223...17,104,853
Ensembl chrNW_004624762:17,038,223...17,104,965
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Otub2
OTU deubiquitinase, ubiquitin aldehyde binding 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:10,384,877...10,404,333
Ensembl chrNW_004624734:10,384,777...10,404,716
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Otulinl
OTU deubiquitinase with linear linkage specificity like
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624751:11,609,538...11,631,446
Ensembl chrNW_004624751:11,609,609...11,630,706
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Palmd
palmdelphin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624857:2,439,874...2,510,130
Ensembl chrNW_004624857:2,439,603...2,514,365
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Pamr1
peptidase domain containing associated with muscle regeneration 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624767:11,681,209...11,753,310
Ensembl chrNW_004624767:11,681,203...11,754,194
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Paqr9
progestin and adipoQ receptor family member 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:19,606,866...19,614,671
Ensembl chrNW_004624730:19,611,971...19,614,689
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Pc
pyruvate carboxylase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624767:19,481,158...19,601,036
Ensembl chrNW_004624767:19,480,522...19,614,051
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Pck1
phosphoenolpyruvate carboxykinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624741:23,985,257...23,990,354
Ensembl chrNW_004624741:23,985,675...23,989,790
G
Pck2
phosphoenolpyruvate carboxykinase 2, mitochondrial
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624820:8,426,456...8,436,484
Ensembl chrNW_004624820:8,426,606...8,436,284
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Pdgfa
platelet derived growth factor subunit A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624740:26,172,808...26,191,557
Ensembl chrNW_004624740:26,169,064...26,188,866
G
Pdgfra
platelet derived growth factor receptor alpha
treatment
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:17382907 PMID:25380136
RGD:11080969
NCBI chrNW_004624761:15,223,789...15,269,685
Ensembl chrNW_004624761:15,225,356...15,269,810
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Pdgfrb
platelet derived growth factor receptor beta
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15077122 PMID:15623374 PMID:18466260
RGD:10449503 RGD:2292206
NCBI chrNW_004624774:9,432,765...9,469,690
Ensembl chrNW_004624774:9,432,541...9,469,881
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Pdxk
pyridoxal kinase
ISO
protein:decreased expression:brain
RGD
PMID:3225873
RGD:2303021
NCBI chrNW_004624745:30,157,446...30,175,905
Ensembl chrNW_004624745:30,157,446...30,175,803
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Pdzrn3
PDZ domain containing ring finger 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624773:7,901,560...8,144,455
Ensembl chrNW_004624773:7,900,934...8,144,003
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Pea15
proliferation and apoptosis adaptor protein 15
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624794:1,041,647...1,051,108
Ensembl chrNW_004624794:1,041,647...1,051,048
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Pfkp
phosphofructokinase, platelet
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624775:7,325,032...7,390,200
Ensembl chrNW_004624775:7,324,662...7,390,271
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Pfn1
profilin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624786:8,803,247...8,805,958
Ensembl chrNW_004624786:8,803,118...8,805,960
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Pgf
placental growth factor
disease_progression
ISO
RGD
PMID:17935226 PMID:21520176
RGD:1643338 RGD:6483607
NCBI chrNW_004624734:26,751,986...26,764,154
Ensembl chrNW_004624734:26,751,530...26,764,242
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Pkd2
polycystin 2, transient receptor potential cation channel
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624872:4,539,965...4,592,004
Ensembl chrNW_004624872:4,539,847...4,594,793
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Pklr
pyruvate kinase L/R
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624885:2,261,850...2,272,175
Ensembl chrNW_004624885:2,264,928...2,272,171
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Pla2g12a
phospholipase A2 group XIIA
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624830:157,705...166,139
Ensembl chrNW_004624830:157,734...166,273
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Pla2g4a
phospholipase A2 group IVA
ISO
CTD Direct Evidence: marker/mechanism protein:increased activity:liver
CTD RGD
PMID:17459512 PMID:25380136
RGD:1642445
NCBI chrNW_004624814:6,597,248...6,744,294
Ensembl chrNW_004624814:6,597,005...6,744,286
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Plac8
placenta associated 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624900:134,075...157,982
Ensembl chrNW_004624900:133,889...158,050
G
Plat
plasminogen activator, tissue type
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:20035854 PMID:25380136
RGD:6484134
NCBI chrNW_004624780:1,014,429...1,063,636
Ensembl chrNW_004624780:1,028,085...1,063,649
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Plau
plasminogen activator, urokinase
treatment
ISO
protein:increased expression:liver (rat) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:16958060 PMID:20035854 PMID:23018346 PMID:25380136
RGD:2317516 RGD:6484134 RGD:7241553
NCBI chrNW_004624754:7,405,637...7,415,870
Ensembl chrNW_004624754:7,408,983...7,416,559
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Pld4
phospholipase D family member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:432,069...439,078
Ensembl chrNW_004624734:431,956...438,170
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Plek
pleckstrin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624762:4,939,683...4,967,327
Ensembl chrNW_004624762:4,939,599...4,967,371
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Plekhb1
pleckstrin homology domain containing B1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624817:3,324,394...3,336,696
Ensembl chrNW_004624817:3,323,743...3,338,257
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Plekhh1
pleckstrin homology, MyTH4 and FERM domain containing H1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:33,411,271...33,456,003
Ensembl chrNW_004624734:33,413,087...33,449,932
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Plg
plasminogen
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:14716496
NCBI chrNW_004624855:2,362,793...2,401,519
Ensembl chrNW_004624855:2,360,229...2,402,079
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Plin2
perilipin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624736:23,114,149...23,122,634
Ensembl chrNW_004624736:23,111,265...23,122,193
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Plin3
perilipin 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624828:4,949,913...4,961,529
Ensembl chrNW_004624828:4,950,718...4,961,177
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Plod2
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:22,944,710...23,034,200
Ensembl chrNW_004624730:22,944,184...23,034,231
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Plpp2
phospholipid phosphatase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624828:8,058,688...8,062,679
Ensembl chrNW_004624828:8,058,329...8,062,677
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Pltp
phospholipid transfer protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624790:8,673,212...8,686,094
Ensembl chrNW_004624790:8,673,089...8,685,942
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Pmepa1
prostate transmembrane protein, androgen induced 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624741:24,053,947...24,103,990
Ensembl chrNW_004624741:24,051,566...24,103,997
G
Pomc
proopiomelanocortin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:16508911 PMID:16511523
NCBI chrNW_004624738:7,442,223...7,448,513
Ensembl chrNW_004624738:7,442,292...7,445,020
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Pparg
peroxisome proliferator activated receptor gamma
treatment
ISO
RGD
PMID:18594976 PMID:22529699
RGD:2301874 RGD:8553190
NCBI chrNW_004624956:84,673...207,176
Ensembl chrNW_004624956:83,842...149,481
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Ppp1r18
protein phosphatase 1 regulatory subunit 18
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:25,027,792...25,034,842
G
Ppp1r3b
protein phosphatase 1 regulatory subunit 3B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624839:5,228,674...5,240,808
Ensembl chrNW_004624839:5,228,674...5,240,816
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Ppp1r3c
protein phosphatase 1 regulatory subunit 3C
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:2,896,677...2,901,393
Ensembl chrNW_004624737:2,893,256...2,901,452
G
Praf2
PRA1 domain family member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624893:842,293...845,494
Ensembl chrNW_004624893:842,071...846,170
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Prkcb
protein kinase C beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624782:8,974,995...9,287,609
Ensembl chrNW_004624782:8,974,765...9,287,702
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Prkcd
protein kinase C delta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624822:4,035,819...4,062,907
Ensembl chrNW_004624822:4,033,130...4,059,555
G
Prkn
parkin RBR E3 ubiquitin protein ligase
treatment
ISO
RGD
PMID:26882442
RGD:12910839
NCBI chrNW_004624855:430,148...1,992,121
Ensembl chrNW_004624855:430,260...1,989,747
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Prlr
prolactin receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624759:19,653,626...19,836,877
Ensembl chrNW_004624759:19,653,600...19,833,848
G
Prnp
prion protein (Kanno blood group)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624741:5,785,139...5,802,162
Ensembl chrNW_004624741:5,785,158...5,802,162
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Procr
protein C receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624842:4,187,635...4,231,277
Ensembl chrNW_004624842:4,226,900...4,231,264
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Prodh2
proline dehydrogenase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624794:10,098,737...10,104,212
G
Pros1
protein S
ISO
mRNA, protein:decreased expression:liver, plasma
RGD
PMID:16995903
RGD:2300011
NCBI chrNW_004624789:6,621,803...6,704,033
G
Prr13
proline rich 13
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624904:1,536,331...1,543,672
G
Prtfdc1
phosphoribosyl transferase domain containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624796:4,014,076...4,095,920
G
Prtg
protogenin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624731:6,005,323...6,109,553
Ensembl chrNW_004624731:6,007,187...6,101,312
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Prune2
prune homolog 2 with BCH domain
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624811:4,095,244...4,403,208
Ensembl chrNW_004624811:4,095,184...4,403,022
G
Psmb10
proteasome 20S subunit beta 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624746:18,442,865...18,445,731
Ensembl chrNW_004624746:18,442,478...18,445,731
G
Psmb8
proteasome 20S subunit beta 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:23,822,965...23,826,367
Ensembl chrNW_004624754:23,823,115...23,826,367
G
Psmb9
proteasome 20S subunit beta 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:23,811,008...23,815,432
Ensembl chrNW_004624754:23,807,272...23,815,417
G
Psme2
proteasome activator subunit 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624820:8,389,348...8,393,498
Ensembl chrNW_004624820:8,389,286...8,393,498
G
Pstpip1
proline-serine-threonine phosphatase interacting protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624894:1,369,242...1,400,765
Ensembl chrNW_004624894:1,368,455...1,400,340
G
Ptafr
platelet activating factor receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624764:11,996,454...12,025,751
Ensembl chrNW_004624764:11,998,657...11,999,685
G
Pter
phosphotriesterase related
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624796:11,248,274...11,301,801
Ensembl chrNW_004624796:11,245,391...11,298,947
G
Ptger2
prostaglandin E receptor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624731:16,729,846...16,741,529
Ensembl chrNW_004624731:16,726,975...16,741,557
G
Ptgs1
prostaglandin-endoperoxide synthase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:12,917,244...12,937,858
Ensembl chrNW_004624760:12,915,206...12,937,824
G
Ptgs2
prostaglandin-endoperoxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17565644 PMID:18555214
NCBI chrNW_004624814:6,897,818...6,904,890
Ensembl chrNW_004624814:6,897,857...6,903,728
G
Ptk2
protein tyrosine kinase 2
ISO
mRNA, protein:increased expression:liver
RGD
PMID:15378782
RGD:2292604
NCBI chrNW_004624735:15,356,911...15,713,219
Ensembl chrNW_004624735:15,461,178...15,714,071
G
Ptn
pleiotrophin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624765:17,523,086...17,625,264
Ensembl chrNW_004624765:17,522,916...17,548,184
G
Ptpn1
protein tyrosine phosphatase non-receptor type 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26739621
NCBI chrNW_004624790:5,070,537...5,135,243
Ensembl chrNW_004624790:5,073,476...5,135,181
G
Ptpn18
protein tyrosine phosphatase non-receptor type 18
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624732:14,495,732...14,545,775
G
Ptprc
protein tyrosine phosphatase receptor type C
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656
G
Ptprd
protein tyrosine phosphatase receptor type D
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624736:12,874,884...13,558,030
Ensembl chrNW_004624736:12,874,706...13,278,956
G
Ptpro
protein tyrosine phosphatase receptor type O
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:22,446,203...22,700,925
Ensembl chrNW_004624752:22,445,311...22,700,904
G
Ptrh1
peptidyl-tRNA hydrolase 1 homolog
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:7,819,765...7,823,011
Ensembl chrNW_004624760:7,819,816...7,821,412
G
Ptrhd1
peptidyl-tRNA hydrolase domain containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624738:7,144,475...7,148,287
Ensembl chrNW_004624738:7,140,799...7,148,979
G
Pxdn
peroxidasin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624846:6,259,807...6,329,849
Ensembl chrNW_004624846:6,259,765...6,331,100
G
Pycard
PYD and CARD domain containing
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624782:14,247,333...14,249,861
Ensembl chrNW_004624782:14,247,864...14,249,000
G
Pycr1
pyrroline-5-carboxylate reductase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624801:10,777,407...10,781,572
Ensembl chrNW_004624801:10,776,747...10,781,614
G
R3hdm2
R3H domain containing 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624802:10,522,075...10,694,396
G
Rab30
RAB30, member RAS oncogene family
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624845:6,809,963...6,917,225
Ensembl chrNW_004624845:6,900,564...6,916,006
G
Rab31
RAB31, member RAS oncogene family
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624770:18,285,140...18,372,389
Ensembl chrNW_004624770:18,285,132...18,372,650
G
Rab32
RAB32, member RAS oncogene family
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624753:7,900,027...7,917,944
Ensembl chrNW_004624753:7,900,267...7,917,854
G
Rab40b
RAB40B, member RAS oncogene family
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624801:11,363,539...11,389,201
Ensembl chrNW_004624801:11,363,537...11,389,183
G
Rab8b
RAB8B, member RAS oncogene family
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624781:9,253,039...9,324,873
Ensembl chrNW_004624781:9,251,212...9,325,642
G
Rabgap1l
RAB GTPase activating protein 1 like
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624771:6,999,341...7,738,571
Ensembl chrNW_004624771:7,004,468...7,738,646
G
Rac2
Rac family small GTPase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:10,589,017...10,620,652
Ensembl chrNW_004624752:10,589,017...10,601,661
G
Ramp1
receptor activity modifying protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624847:3,169,339...3,202,393
Ensembl chrNW_004624847:3,169,360...3,202,389
G
Ramp2
receptor activity modifying protein 2
ISO
RGD
PMID:16713642
RGD:1625319
NCBI chrNW_004624795:1,435,121...1,436,421
G
Rarres1
retinoic acid receptor responder 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:36,404,953...36,434,723
Ensembl chrNW_004624730:36,405,270...36,434,630
G
Rbl2
RB transcriptional corepressor like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624757:3,295,471...3,351,539
Ensembl chrNW_004624757:3,295,479...3,351,928
G
Rbm3
RNA binding motif protein 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624893:403,831...407,772
Ensembl chrNW_004624893:403,916...411,708
G
Rbp4
retinol binding protein 4
ISO
mRNA:increased expression:liver (rat)
RGD
PMID:17337499
RGD:329845879
NCBI chrNW_004624737:4,795,054...4,800,830
Ensembl chrNW_004624737:4,791,628...4,800,989
G
Rcn1
reticulocalbin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624766:20,732,395...20,740,256
Ensembl chrNW_004624766:20,732,396...20,740,839
G
Rcn2
reticulocalbin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624894:1,431,375...1,450,156
Ensembl chrNW_004624894:1,429,107...1,450,515
G
Rcsd1
RCSD domain containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624826:5,673,114...5,745,948
Ensembl chrNW_004624826:5,729,704...5,744,327
G
Rdh10
retinol dehydrogenase 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624744:17,838,047...17,868,423
Ensembl chrNW_004624744:17,837,609...17,868,431
G
Rdh13
retinol dehydrogenase 13
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:27865848
NCBI chrNW_004624832:2,141,906...2,159,009
Ensembl chrNW_004624832:2,141,902...2,159,009
G
Reck
reversion inducing cysteine rich protein with kazal motifs
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624868:4,604,157...4,713,838
Ensembl chrNW_004624868:4,603,955...4,713,652
G
Reep5
receptor accessory protein 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624743:30,690,339...30,729,229
Ensembl chrNW_004624743:30,690,350...30,729,785
G
Rela
RELA proto-oncogene, NF-kB subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26806094
NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272
G
Rell1
RELT like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624840:6,207,560...6,268,193
Ensembl chrNW_004624840:6,207,394...6,268,205
G
Reln
reelin
ISO
mRNA, protein:increased expression:liver, plasma (rat)
RGD
PMID:18449964
RGD:2317777
NCBI chrNW_004624739:25,472,626...25,918,064
Ensembl chrNW_004624739:25,472,561...25,918,167
G
Rgn
regucalcin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624887:3,881,624...3,900,144
Ensembl chrNW_004624887:3,883,213...3,899,277
G
Rgs10
regulator of G protein signaling 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:27,284,123...27,319,169
Ensembl chrNW_004624737:27,284,131...27,321,642
G
Rgs2
regulator of G protein signaling 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624814:754,743...758,148
Ensembl chrNW_004624814:753,164...758,192
G
Rgs3
regulator of G protein signaling 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:21,514,359...21,636,684
G
Rgs5
regulator of G protein signaling 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624826:1,644,874...1,698,855
Ensembl chrNW_004624826:1,648,891...1,699,353
G
Rhoa
ras homolog family member A
ISO
mRNA, protein:increased expression:liver
RGD
PMID:16492715 PMID:17596891
RGD:1642803 RGD:2298879
NCBI chrNW_004624730:3,316,122...3,361,820
G
Rhoq
ras homolog family member Q
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624738:27,997,493...28,031,840
G
Rida
reactive intermediate imine deaminase A homolog
treatment
ISO
RGD
PMID:23075396
RGD:9685568
NCBI chrNW_004624763:5,249,905...5,263,994
Ensembl chrNW_004624763:5,247,715...5,263,880
G
Rit1
Ras like without CAAX 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624885:1,275,765...1,284,613
G
Rmdn2
regulator of microtubule dynamics 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624738:19,533,915...19,624,796
G
Rmnd5b
required for meiotic nuclear division 5 homolog B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624733:41,357,840...41,371,203
Ensembl chrNW_004624733:41,358,910...41,375,513
G
Rnasel
ribonuclease L
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624814:11,268,725...11,319,023
Ensembl chrNW_004624814:11,268,698...11,305,221
G
Rnf39
ring finger protein 39
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:25,331,126...25,348,957
Ensembl chrNW_004624754:25,331,070...25,335,153
G
Robo2
roundabout guidance receptor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624745:800,963...2,121,445
Ensembl chrNW_004624745:804,797...1,390,551
G
Rph3al
rabphilin 3A like (without C2 domains)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624786:3,847,750...3,997,985
Ensembl chrNW_004624786:3,900,081...3,998,091
G
Rtn4
reticulon 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624833:6,514,409...6,584,061
G
Rtp3
receptor transporter protein 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:74,605,692...74,609,946
G
Rxra
retinoid X receptor alpha
ISO
RGD
PMID:15566521
RGD:1643114
NCBI chrNW_004624760:2,379,809...2,455,749
Ensembl chrNW_004624760:2,380,708...2,456,928
G
S100a10
S100 calcium binding protein A10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624772:19,597,909...19,608,352
Ensembl chrNW_004624772:19,597,942...19,608,271
G
S100a11
S100 calcium binding protein A11
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624772:19,563,871...19,568,413
Ensembl chrNW_004624772:19,563,889...19,568,766
G
S100a9
S100 calcium binding protein A9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624885:767,455...770,023
Ensembl chrNW_004624885:762,934...770,129
G
S1pr1
sphingosine-1-phosphate receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624857:4,143,269...4,147,877
Ensembl chrNW_004624857:4,143,270...4,147,877
G
Samd11
sterile alpha motif domain containing 11
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624818:8,563,376...8,581,028
Ensembl chrNW_004624818:8,563,879...8,581,015
G
Sash3
SAM and SH3 domain containing 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624797:9,001,846...9,017,441
Ensembl chrNW_004624797:9,001,795...9,018,027
G
Sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624746:5,494,792...5,504,615
Ensembl chrNW_004624746:5,494,404...5,506,172
G
Sds
serine dehydratase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624747:19,124,706...19,131,757
Ensembl chrNW_004624747:19,123,927...19,132,307
G
Selenom
selenoprotein M
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624747:7,582,259...7,584,903
Ensembl chrNW_004624747:7,582,446...7,584,673
G
Selenop
selenoprotein P
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624759:12,207,251...12,218,857
G
Selenow
selenoprotein W
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624832:6,129,073...6,132,619
G
Selp
selectin P
ISO
protein:increased expression:bone marrow
RGD
PMID:19333758
RGD:2312308
NCBI chrNW_004624826:7,510,039...7,544,332
Ensembl chrNW_004624826:7,511,646...7,537,924
G
Sema6d
semaphorin 6D
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624731:11,914,530...12,269,463
Ensembl chrNW_004624731:11,914,422...11,970,138
G
Senp2
SUMO specific peptidase 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:29535048
NCBI chrNW_004624730:71,068,112...71,100,121
Ensembl chrNW_004624730:71,068,112...71,100,225
G
Serpina6
serpin family A member 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:10,638,031...10,650,297
Ensembl chrNW_004624734:10,637,515...10,651,033
G
Serpina7
serpin family A member 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624803:10,622,181...10,627,652
Ensembl chrNW_004624803:10,622,140...10,630,845
G
Serpinc1
serpin family C member 1
treatment
ISO
associated with Inflammatory Bowel Diseases
RGD
PMID:16124052
RGD:1599330
NCBI chrNW_004624771:7,955,778...7,966,637
Ensembl chrNW_004624771:7,955,739...7,966,637
G
Serpinh1
serpin family H member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18376398 PMID:25380136
NCBI chrNW_004624817:1,561,471...1,570,425
Ensembl chrNW_004624817:1,561,471...1,570,947
G
Sez6
seizure related 6 homolog
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624786:1,520,548...1,567,787
Ensembl chrNW_004624786:1,518,420...1,567,879
G
Sgcb
sarcoglycan beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624761:17,670,920...17,690,513
Ensembl chrNW_004624761:17,670,887...17,688,659
G
Sgk2
serum/glucocorticoid regulated kinase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624790:10,727,125...10,749,060
Ensembl chrNW_004624790:10,726,486...10,752,235
G
Sh3bgrl3
SH3 domain binding glutamate rich protein like 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624764:10,317,026...10,318,562
Ensembl chrNW_004624764:10,317,031...10,318,635
G
Shcbp1
SHC binding and spindle associated 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624914:39,197...107,922
G
Shisa3
shisa family member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624761:24,514,251...24,519,253
Ensembl chrNW_004624761:24,511,759...24,519,251
G
Siglec5
sialic acid binding Ig like lectin 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624832:3,387,527...3,422,859
G
Sirt1
sirtuin 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:26435214
NCBI chrNW_004624754:2,304,476...2,332,705
Ensembl chrNW_004624754:2,304,634...2,330,946
G
Skil
SKI like proto-oncogene
ISO
RGD
PMID:19189315
RGD:2308901
NCBI chrNW_004624730:48,376,625...48,404,059
Ensembl chrNW_004624730:48,377,499...48,404,141
G
Sla
Src like adaptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624735:22,929,467...22,949,471
Ensembl chrNW_004624735:22,892,713...22,950,355
G
Slamf9
SLAM family member 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624794:1,244,829...1,308,494
Ensembl chrNW_004624794:1,305,409...1,307,669
G
Slc10a1
solute carrier family 10 member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624734:31,287,539...31,307,339
Ensembl chrNW_004624734:31,287,394...31,311,357
G
Slc12a3
solute carrier family 12 member 3
ISO
protein:altered expression:kidney (rat)
RGD
PMID:15956070
RGD:1580587
NCBI chrNW_004624746:29,087,867...29,132,793
Ensembl chrNW_004624746:29,098,254...29,132,752
G
Slc15a3
solute carrier family 15 member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624926:294,263...303,326
Ensembl chrNW_004624926:294,376...303,248
G
Slc17a1
solute carrier family 17 member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980 PMID:25380136
NCBI chrNW_004624756:1,195,037...1,261,771
Ensembl chrNW_004624756:1,196,891...1,249,390
G
Slc17a2
solute carrier family 17 member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624756:1,088,919...1,119,361
Ensembl chrNW_004624756:1,088,943...1,106,509
G
Slc19a2
solute carrier family 19 member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624826:7,382,158...7,400,702
Ensembl chrNW_004624826:7,380,827...7,400,665
G
Slc20a1
solute carrier family 20 member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624749:12,631,259...12,702,867
G
Slc22a23
solute carrier family 22 member 23
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624756:21,532,541...21,689,471
Ensembl chrNW_004624756:21,533,394...21,686,357
G
Slc22a8
solute carrier family 22 member 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624926:1,373,804...1,390,248
Ensembl chrNW_004624926:1,374,103...1,388,586
G
Slc23a1
solute carrier family 23 member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624743:32,169,051...32,186,618
Ensembl chrNW_004624743:32,174,922...32,186,697
G
Slc25a13
solute carrier family 25 member 13
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624813:2,851,620...3,019,593
Ensembl chrNW_004624813:2,852,585...2,998,651
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Slc25a24
solute carrier family 25 member 24
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624772:4,280,055...4,324,403
Ensembl chrNW_004624772:4,278,655...4,324,510
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Slc25a30
solute carrier family 25 member 30
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624748:9,564,872...9,589,266
Ensembl chrNW_004624748:9,567,769...9,583,023
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Slc25a4
solute carrier family 25 member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624769:15,989,527...15,993,609
Ensembl chrNW_004624769:15,989,547...15,997,680
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Slc37a4
solute carrier family 37 member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17072980
NCBI chrNW_004624784:14,415,385...14,421,953
Ensembl chrNW_004624784:14,415,395...14,421,944
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Slc39a6
solute carrier family 39 member 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624779:10,400,581...10,433,405
Ensembl chrNW_004624779:10,399,198...10,432,869
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Slc39a8
solute carrier family 39 member 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624830:5,514,595...5,573,250
Ensembl chrNW_004624830:5,514,780...5,574,894
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Slc43a2
solute carrier family 43 member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624786:4,284,559...4,334,086
Ensembl chrNW_004624786:4,288,745...4,334,246
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Slc44a2
solute carrier family 44 member 2 (CTL2 blood group)
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624828:2,655,107...2,678,347
Ensembl chrNW_004624828:2,655,113...2,677,135
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Slc46a1
solute carrier family 46 member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624786:1,000,444...1,006,984
Ensembl chrNW_004624786:1,000,444...1,007,375
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Slc4a4
solute carrier family 4 member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624890:2,523,368...2,940,081
Ensembl chrNW_004624890:2,523,327...2,919,148
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Slc66a3
solute carrier family 66 member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624865:4,592,697...4,599,213
Ensembl chrNW_004624865:4,592,973...4,599,232
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Slc7a1
solute carrier family 7 member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624776:8,859,519...8,935,370
Ensembl chrNW_004624776:8,897,489...8,934,722
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Smad1
SMAD family member 1
ISO
RGD
PMID:16447265
RGD:1643229
NCBI chrNW_004624853:4,415,816...4,503,317
Ensembl chrNW_004624853:4,444,876...4,502,496
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Smad2
SMAD family member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16570350
NCBI chrNW_004624778:11,380,656...11,460,566
Ensembl chrNW_004624778:11,384,769...11,501,078
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Smad3
SMAD family member 3
treatment
ISO
RGD
PMID:30346985
RGD:151665755
NCBI chrNW_004624781:5,795,652...5,890,047
Ensembl chrNW_004624781:5,795,652...5,890,371
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Smad4
SMAD family member 4
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:16570350 PMID:19824107
RGD:12903949
NCBI chrNW_004624778:14,570,025...14,629,950
Ensembl chrNW_004624778:14,570,348...14,630,325
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Smarcc1
SWI/SNF related BAF chromatin remodeling complex subunit C1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:73,696,734...73,856,082
Ensembl chrNW_004624730:73,696,749...73,856,082
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Smc2
structural maintenance of chromosomes 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624758:7,267,024...7,318,930
Ensembl chrNW_004624758:7,268,474...7,317,919
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Smc5
structural maintenance of chromosomes 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624736:2,697,764...2,803,501
Ensembl chrNW_004624736:2,700,161...2,803,439
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Smoc1
SPARC related modular calcium binding 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:31,051,637...31,199,911
Ensembl chrNW_004624734:31,048,828...31,199,974
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Smoc2
SPARC related modular calcium binding 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624850:4,510,700...4,658,579
Ensembl chrNW_004624850:4,510,598...4,661,056
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Snap23
synaptosome associated protein 23
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624804:9,609,777...9,643,670
Ensembl chrNW_004624804:9,610,308...9,641,933
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Snap29
synaptosome associated protein 29
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624945:799,831...837,720
Ensembl chrNW_004624945:801,833...837,564
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Snx7
sorting nexin 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624857:1,253,148...1,365,322
Ensembl chrNW_004624857:1,252,995...1,365,308
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Soat1
sterol O-acyltransferase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624771:2,992,752...3,055,842
Ensembl chrNW_004624771:2,994,696...3,055,916
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Socs1
suppressor of cytokine signaling 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15197228
NCBI chrNW_004624824:8,444,877...8,446,628
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Socs2
suppressor of cytokine signaling 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624750:13,333,393...13,339,018
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Sox4
SRY-box transcription factor 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624756:5,128,848...5,156,174
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Sparc
secreted protein acidic and cysteine rich
ISO
mRNA:increased expression:liver, fat cell CTD Direct Evidence: marker/mechanism|therapeutic
RGD CTD
PMID:8786698 PMID:18615449 PMID:25380136
RGD:2300030 RGD:2300071
NCBI chrNW_004624733:37,348,993...37,369,804
Ensembl chrNW_004624733:37,338,284...37,369,804
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Spp1
secreted phosphoprotein 1
ISO
RGD
PMID:16221502
RGD:1581332
NCBI chrNW_004624872:4,505,796...4,513,247
Ensembl chrNW_004624872:4,505,522...4,513,742
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Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:17,692,124...17,774,321
Ensembl chrNW_004624730:17,692,959...17,774,497
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Sptan1
spectrin alpha, non-erythrocytic 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:6,331,554...6,388,953
Ensembl chrNW_004624760:6,331,554...6,386,216
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Srd5a1
steroid 5 alpha-reductase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624751:4,309,518...4,335,332
Ensembl chrNW_004624751:4,309,447...4,336,083
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Srebf1
sterol regulatory element binding transcription factor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624849:3,602,103...3,623,922
Ensembl chrNW_004624849:3,602,261...3,623,465
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Srgn
serglycin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:3,379,651...3,412,175
Ensembl chrNW_004624754:3,401,480...3,411,488
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Sri
sorcin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624809:5,160,731...5,187,914
Ensembl chrNW_004624809:5,160,737...5,191,514
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Srr
serine racemase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624786:4,969,742...4,988,874
Ensembl chrNW_004624786:4,977,574...4,988,945
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St14
ST14 transmembrane serine protease matriptase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624812:4,584,043...4,620,410
Ensembl chrNW_004624812:4,583,946...4,620,547
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Stac3
SH3 and cysteine rich domain 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624802:10,694,539...10,704,320
Ensembl chrNW_004624802:10,695,870...10,704,334
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Stard13
StAR related lipid transfer domain containing 13
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624776:3,998,594...4,539,815
Ensembl chrNW_004624776:4,371,126...4,540,711
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Stat3
signal transducer and activator of transcription 3
treatment
ISO
RGD
PMID:30346985
RGD:151665755
NCBI chrNW_004624795:1,648,235...1,680,788
Ensembl chrNW_004624795:1,648,080...1,681,200
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Stau2
staufen double-stranded RNA binding protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624744:17,434,733...17,726,348
Ensembl chrNW_004624744:17,434,686...17,727,127
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Steap4
STEAP4 metalloreductase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624809:5,084,992...5,103,765
Ensembl chrNW_004624809:5,084,814...5,103,980
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Stk10
serine/threonine kinase 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624733:17,829,802...17,955,643
Ensembl chrNW_004624733:17,829,773...17,949,532
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Synrg
synergin gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624871:4,505,693...4,593,472
Ensembl chrNW_004624871:4,509,428...4,593,337
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Tagln2
transgelin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624794:1,331,075...1,338,445
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Tap2
transporter 2, ATP binding cassette subfamily B member
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:23,827,782...23,845,690
Ensembl chrNW_004624754:23,827,706...23,837,356
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Tax1bp3
Tax1 binding protein 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624786:6,318,879...6,323,835
Ensembl chrNW_004624786:6,318,879...6,323,816
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Tbc1d9
TBC1 domain family member 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624853:36,571...151,871
Ensembl chrNW_004624853:36,464...151,309
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Tcf20
transcription factor 20
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:6,446,414...6,537,238
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Tcf4
transcription factor 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624792:686,360...1,030,199
Ensembl chrNW_004624792:686,774...1,027,397
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Tert
telomerase reverse transcriptase
ISO
protein:increased expression, increased localization:nucleus
RGD
PMID:20353272
RGD:11038673
NCBI chrNW_004624751:624,569...647,198
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Tes
testin LIM domain protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624827:3,208,246...3,248,942
Ensembl chrNW_004624827:3,206,196...3,249,025
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Tfec
transcription factor EC
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624827:3,472,157...3,498,689
Ensembl chrNW_004624827:3,426,277...3,496,989
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Tfpi2
tissue factor pathway inhibitor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624813:571,592...577,268
Ensembl chrNW_004624813:571,414...577,858
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Tgfb1
transforming growth factor beta 1
onset treatment
ISO
associated with extrahepatic cholestasis CTD Direct Evidence: marker/mechanism|therapeutic associated with Chemical and Drug Induced Liver Injury protein:increased expression:liver mRNA:increased expression:liver (mouse)
RGD CTD
PMID:12586293 PMID:15772939 PMID:16009107 PMID:16579972 PMID:26806094 PMID:27528511 PMID:27605418 PMID:28390311 PMID:28465467 PMID:30092114 PMID:30243650 More...
RGD:14985231 RGD:14985232 RGD:14985234 RGD:14995475 RGD:1601595 RGD:39939037
NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605
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Tgfb3
transforming growth factor beta 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624734:25,717,011...25,739,942
Ensembl chrNW_004624734:25,716,972...25,739,199
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Tgfbr1
transforming growth factor beta receptor 1
ISO
protein:increased expression:liver
RGD
PMID:15723089 PMID:16009107
RGD:1601595 RGD:2302027
NCBI chrNW_004624825:1,773,158...1,899,120
Ensembl chrNW_004624825:1,839,178...1,899,156
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Tgfbr2
transforming growth factor beta receptor 2
treatment
ISO
CTD Direct Evidence: therapeutic
CTD RGD
PMID:15942678 PMID:16627068 PMID:30346985
RGD:151665755 RGD:1579923
NCBI chrNW_004624788:8,447,679...8,535,821
Ensembl chrNW_004624788:8,447,542...8,535,959
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Th
tyrosine hydroxylase
ISO
mRNA:decreased expression:superior mesenteric artery (rat)
RGD
PMID:18457899
RGD:5129683
NCBI chrNW_004624767:15,003,073...15,010,207
Ensembl chrNW_004624767:15,003,092...15,010,154
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Thbd
thrombomodulin
ISO
CTD Direct Evidence: marker/mechanism protein:increased expression:liver
CTD RGD
PMID:21112949 PMID:25380136
RGD:5685038
NCBI chrNW_004624741:22,880,481...22,883,962
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Thpo
thrombopoietin
ISO
mRNA:decreased expression:liver
RGD
PMID:9794189
RGD:1580082
NCBI chrNW_004624730:72,210,880...72,218,615
Ensembl chrNW_004624730:72,212,423...72,219,485
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Thyn1
thymocyte nuclear protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624812:8,805,196...8,810,559
Ensembl chrNW_004624812:8,805,196...8,810,582
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Tial1
TIA1 cytotoxic granule associated RNA binding protein like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624737:27,236,533...27,259,464
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Timp1
TIMP metallopeptidase inhibitor 1
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:liver
CTD RGD
PMID:8707259 PMID:16507762 PMID:16718785 PMID:16762003 PMID:21163135 PMID:25380136 More...
RGD:2290364
NCBI chrNW_004624978:120,723...125,006
Ensembl chrNW_004624978:121,803...124,912
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Timp2
TIMP metallopeptidase inhibitor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624801:8,228,618...8,270,606
Ensembl chrNW_004624801:8,228,357...8,270,982
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Tkfc
triokinase and FMN cyclase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624926:862,339...870,936
Ensembl chrNW_004624926:862,339...869,926
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Tlr2
toll like receptor 2
treatment
ISO
RGD
PMID:22683883 PMID:27601294
RGD:18182936 RGD:7241092
NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833
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Tlr3
toll like receptor 3
ISO
RGD
PMID:27178735
RGD:21079415
NCBI chrNW_004624769:16,925,969...16,945,250
Ensembl chrNW_004624769:16,925,984...16,941,196
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Tlr4
toll like receptor 4
treatment
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:22683883 PMID:25380136 PMID:27601294
RGD:18182936 RGD:7241092
NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120
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Tm6sf1
transmembrane 6 superfamily member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624768:18,870,074...18,899,859
Ensembl chrNW_004624768:18,870,076...18,895,623
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Tmbim1
transmembrane BAX inhibitor motif containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624823:6,736,216...6,757,285
Ensembl chrNW_004624823:6,735,497...6,756,093
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Tmem106a
transmembrane protein 106A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624875:9,045...16,541
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Tmem165
transmembrane protein 165
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624761:14,039,698...14,066,750
Ensembl chrNW_004624761:14,038,758...14,066,894
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Tmem178a
transmembrane protein 178A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624738:21,153,660...21,211,592
Ensembl chrNW_004624738:21,152,816...21,212,770
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Tmem184b
transmembrane protein 184B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:9,722,520...9,770,009
Ensembl chrNW_004624752:9,740,116...9,770,009
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Tmem43
transmembrane protein 43
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624872:1,467,531...1,481,057
Ensembl chrNW_004624872:1,467,440...1,481,044
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Tmem65
transmembrane protein 65
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624735:30,805,189...30,868,059
Ensembl chrNW_004624735:30,805,189...30,866,490
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Tmsb10
thymosin beta 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624749:18,147,755...18,148,834
Ensembl chrNW_004624749:18,147,637...18,148,862
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Tnf
tumor necrosis factor
treatment
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:liver (mouse)
CTD RGD
PMID:16085334 PMID:24383550 PMID:28465467
RGD:10450610 RGD:39939037
NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531
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Tnfaip8
TNF alpha induced protein 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624733:2,272,634...2,397,002
Ensembl chrNW_004624733:2,271,825...2,396,307
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Tor4a
torsin family 4 member A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:686,754...692,557
Ensembl chrNW_004624760:686,768...690,397
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Tpm1
tropomyosin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624781:9,414,500...9,442,357
Ensembl chrNW_004624781:9,414,500...9,442,544
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Tpm3
tropomyosin 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624885:3,109,360...3,139,664
Ensembl chrNW_004624885:3,109,436...3,139,789
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Tpm4
tropomyosin 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624908:1,135,240...1,155,175
Ensembl chrNW_004624908:1,132,215...1,152,319
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Trafd1
TRAF-type zinc finger domain containing 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624747:20,034,803...20,057,197
G
Trak2
trafficking kinesin protein 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624899:275,291...335,555
Ensembl chrNW_004624899:300,096...332,392
G
Trib3
tribbles pseudokinase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624741:1,486,223...1,494,005
Ensembl chrNW_004624741:1,484,863...1,494,829
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Trim24
tripartite motif containing 24
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624765:18,966,663...19,079,857
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Trim59
tripartite motif containing 59
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:38,178,975...38,192,922
Ensembl chrNW_004624730:38,181,060...38,192,885
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Trpv1
transient receptor potential cation channel subfamily V member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17043671
NCBI chrNW_004624786:6,231,494...6,249,001
Ensembl chrNW_004624786:6,231,494...6,249,001
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Tsc22d1
TSC22 domain family member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624748:10,420,584...10,589,366
Ensembl chrNW_004624748:10,420,659...10,592,135
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Tspan8
tetraspanin 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624750:26,634,019...26,668,779
Ensembl chrNW_004624750:26,633,793...26,669,980
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Tspo
translocator protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624752:5,814,784...5,820,250
Ensembl chrNW_004624752:5,814,784...5,820,141
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Tstd3
thiosulfate sulfurtransferase like domain containing 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624810:5,487,669...5,498,787
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Ttc36
tetratricopeptide repeat domain 36
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624784:13,913,218...13,931,581
Ensembl chrNW_004624784:13,913,225...13,931,581
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Tubb6
tubulin beta 6 class V
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624770:19,580,623...19,590,617
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Tusc3
tumor suppressor candidate 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624839:1,125,643...1,453,961
G
Tyrobp
transmembrane immune signaling adaptor TYROBP
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624794:10,183,934...10,187,180
Ensembl chrNW_004624794:10,183,515...10,187,244
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U2surp
U2 snRNP associated SURP domain containing
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:19,645,733...19,694,866
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Ugcg
UDP-glucose ceramide glucosyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:23,059,141...23,094,013
Ensembl chrNW_004624760:23,056,929...23,094,010
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Unc5cl
unc-5 family C-terminal like
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:17,713,111...17,723,735
Ensembl chrNW_004624754:17,713,361...17,724,276
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Unc93b1
unc-93 homolog B1, TLR signaling regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624767:18,859,990...18,869,083
Ensembl chrNW_004624767:18,860,017...18,868,581
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Vasp
vasodilator stimulated phosphoprotein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624832:7,619,211...7,631,576
Ensembl chrNW_004624832:7,619,134...7,630,943
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Vav1
vav guanine nucleotide exchange factor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624828:3,838,464...3,896,698
Ensembl chrNW_004624828:3,838,706...3,897,080
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Vegfa
vascular endothelial growth factor A
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
PMID:18416461 PMID:18458672
NCBI chrNW_004624754:15,929,414...15,943,637
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Vim
vimentin
ISO
CTD Direct Evidence: marker/mechanism associated with Schistosomiasis Japonica; mRNA:increased expression:liver (rat)
CTD RGD
PMID:25380136 PMID:29323718
RGD:38599216
NCBI chrNW_004624796:10,624,672...10,632,300
Ensembl chrNW_004624796:10,623,929...10,632,600
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Vipr1
vasoactive intestinal peptide receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624730:77,128,547...77,155,531
Ensembl chrNW_004624730:77,128,649...77,153,750
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Vopp1
VOPP1 WW domain binding protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624740:375,651...470,841
Ensembl chrNW_004624740:375,944...469,111
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Vsir
V-set immunoregulatory receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624754:5,664,899...5,686,675
Ensembl chrNW_004624754:5,665,445...5,686,692
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Vwf
von Willebrand factor
ISO
CTD Direct Evidence: marker/mechanism protein:increased expression:liver:
CTD RGD
PMID:7531171 PMID:28527913
RGD:11079232
NCBI chrNW_004624860:2,843,268...2,973,888
Ensembl chrNW_004624860:2,858,088...2,973,052
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Wfdc2
WAP four-disulfide core domain 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624790:8,928,002...8,934,503
G
Wipf1
WAS/WASL interacting protein family member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624787:11,787,384...11,908,727
Ensembl chrNW_004624787:11,787,295...11,822,523
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Wls
Wnt ligand secretion mediator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624742:27,481,480...27,570,439
Ensembl chrNW_004624742:27,481,427...27,570,439
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Xpnpep2
X-prolyl aminopeptidase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624797:8,962,080...8,992,049
Ensembl chrNW_004624797:8,961,835...8,992,767
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Ybx1
Y-box binding protein 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:16012952
NCBI chrNW_004624892:1,939,641...1,957,621
Ensembl chrNW_004624892:1,939,098...1,957,623
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Ypel3
yippee like 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624782:13,164,713...13,168,818
Ensembl chrNW_004624782:13,165,056...13,171,634
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Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624740:14,960,105...14,995,522
Ensembl chrNW_004624740:14,959,089...14,995,548
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Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624763:7,722,275...7,723,482
G
Zbtb4
zinc finger and BTB domain containing 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624786:10,067,503...10,085,500
Ensembl chrNW_004624786:10,066,801...10,085,482
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Zdhhc13
zinc finger DHHC-type palmitoyltransferase 13
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624766:10,556,715...10,608,070
Ensembl chrNW_004624766:10,556,645...10,608,083
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Zdhhc2
zinc finger DHHC-type palmitoyltransferase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624769:22,078,361...22,151,679
Ensembl chrNW_004624769:22,080,073...22,151,626
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Zeb2
zinc finger E-box binding homeobox 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624732:44,097,348...44,226,701
Ensembl chrNW_004624732:44,101,613...44,139,997
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Zfp37
ZFP37 zinc finger protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624760:22,033,252...22,044,416
Ensembl chrNW_004624760:22,038,706...22,043,296
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Zfyve16
zinc finger FYVE-type containing 16
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25380136
NCBI chrNW_004624743:1,339,650...1,383,883
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Krt18
keratin 18
susceptibility
ISO
ClinVar Annotator: match by term: Cirrhosis, familial | ClinVar Annotator: match by term: Cirrhosis, noncryptogenic, susceptibility to
ClinVar OMIM
PMID:9011570 PMID:12724528 PMID:25741868
NCBI chrNW_004624904:1,011,675...1,015,319
Ensembl chrNW_004624904:1,011,755...1,015,416
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Krt8
keratin 8
ISO
ClinVar Annotator: match by term: Cirrhosis, familial | ClinVar Annotator: match by term: Cirrhosis, noncryptogenic, susceptibility to
ClinVar
PMID:9011570 PMID:12724528 PMID:25741868
NCBI chrNW_004624904:970,136...978,211
G
Tjp2
tight junction protein 2
ISO
ClinVar Annotator: match by term: Familial primary biliary cirrhosis
ClinVar
PMID:25741868 PMID:28492532 PMID:32439973
NCBI chrNW_004624736:3,833,402...4,009,385
Ensembl chrNW_004624736:3,834,548...3,878,828
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Tulp3
TUB like protein 3
ISO
ClinVar Annotator: match by term: Hepatorenocardiac degenerative fibrosis
OMIM ClinVar
PMID:25741868 PMID:35397207
NCBI chrNW_004624860:232,838...301,299
Ensembl chrNW_004624860:232,936...299,225
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Slc30a10
solute carrier family 30 member 10
ISO
ClinVar Annotator: match by term: Dystonia/Parkinsonism, Hypermanganesemia, Polycythemia, and Chronic Liver Disease | ClinVar Annotator: match by term: Hypermanganesemia with dystonia 1 | ClinVar Annotator: match by term: Hypermanganesemia with dystonia, polycythemia, and cirrhosis
OMIM ClinVar
PMID:11040156 PMID:18392750 PMID:22341971 PMID:22341972 PMID:22934317 PMID:25741868 PMID:27117033 PMID:28492532 PMID:30272946 PMID:31594250 PMID:34315874 More...
NCBI chrNW_004624835:3,598,375...3,612,165
Ensembl chrNW_004624835:3,598,260...3,611,307
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Utp4
UTP4 small subunit processome component
ISO
ClinVar Annotator: match by term: Hereditary North American Indian childhood cirrhosis
ClinVar
PMID:9536098 PMID:12417987 PMID:16225863 PMID:17576681 PMID:19732766 PMID:20385600 PMID:22916032 PMID:24123366 PMID:25741868 PMID:27535533 PMID:28492532 More...
NCBI chrNW_004624746:17,176,390...17,205,960
Ensembl chrNW_004624746:17,172,124...17,206,262
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Abca1
ATP binding cassette subfamily A member 1
ISO
mRNA:increased expression:liver (human)
RGD
PMID:28660384
RGD:21203516
NCBI chrNW_004624758:6,449,583...6,590,244
Ensembl chrNW_004624758:6,449,629...6,588,664
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Abcc2
ATP binding cassette subfamily C member 2
ISO
CTD Direct Evidence: marker/mechanism protein:decreased expression:liver
CTD RGD
PMID:15542527 PMID:15770136
RGD:14700810
NCBI chrNW_004624737:11,593,701...11,686,790
Ensembl chrNW_004624737:11,593,864...11,688,460
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Ace
angiotensin I converting enzyme
ISO
mRNA:increased expression:liver
RGD
PMID:19389807
RGD:2325226
NCBI chrNW_004624849:998,262...1,019,305
Ensembl chrNW_004624849:998,277...1,019,521
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Ace2
angiotensin converting enzyme 2
ISO
mRNA, protein:increased expression:liver
RGD
PMID:17532087
RGD:9685452
NCBI chrNW_004624829:344,823...391,451
Ensembl chrNW_004624829:344,933...391,527
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Agt
angiotensinogen
ISO
protein:increased expression:plasma
RGD
PMID:17532087
RGD:9685452
NCBI chrNW_004624775:18,846,222...18,856,093
Ensembl chrNW_004624775:18,849,118...18,855,577
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Alb
albumin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30026087
NCBI chrNW_004624735:34,105,237...34,123,479
Ensembl chrNW_004624735:34,104,537...34,123,624
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Aqp4
aquaporin 4
ISO
RGD
PMID:20451280
RGD:5148030
NCBI chrNW_004624770:5,581,192...5,593,470
Ensembl chrNW_004624770:5,580,808...5,594,628
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Ca1
carbonic anhydrase 1
ISO
RGD
PMID:12806141
RGD:408425977
NCBI chrNW_004624744:6,244,872...6,324,722
Ensembl chrNW_004624744:6,314,872...6,333,003
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Ca2
carbonic anhydrase 2
ISO
RGD
PMID:12806141
RGD:408425977
NCBI chrNW_004624744:6,168,030...6,183,407
Ensembl chrNW_004624744:6,167,606...6,183,538
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Ccl5
C-C motif chemokine ligand 5
ISO
mRNA:increased expression:liver: CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:12126966 PMID:15770052
RGD:14995336
NCBI chrNW_004624875:3,334,136...3,342,085
Ensembl chrNW_004624875:3,334,078...3,341,614
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Ccn2
cellular communication network factor 2
ISO
mRNA:increased expression:liver (rat)
RGD
PMID:19371232
RGD:2314517
NCBI chrNW_004624753:6,022,033...6,024,866
Ensembl chrNW_004624753:6,023,069...6,024,833
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Cd14
CD14 molecule
disease_progression
ISO
protein:increased expression:liver (human)
RGD
PMID:21275501
RGD:407420272
NCBI chrNW_004624743:33,372,023...33,374,438
Ensembl chrNW_004624743:33,367,898...33,373,922
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Cd3d
CD3d molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18422935
NCBI chrNW_004624784:13,733,465...13,754,248
Ensembl chrNW_004624784:13,733,403...13,737,356
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Cd68
CD68 molecule
disease_progression
ISO
protein:increased expression:liver (human)
RGD
PMID:21275501
RGD:407420272
NCBI chrNW_004624786:10,195,337...10,197,963
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Cd80
CD80 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21399635
NCBI chrNW_004624731:28,630,540...28,655,297
Ensembl chrNW_004624731:28,630,446...28,651,994
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Cdh5
cadherin 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18422935
NCBI chrNW_004624746:20,028,952...20,068,029
Ensembl chrNW_004624746:20,033,008...20,057,595
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Cdkn1a
cyclin dependent kinase inhibitor 1A
ISO
protein:increased expression:epithelial cell:
RGD
PMID:18456456
RGD:8662434
NCBI chrNW_004624754:21,109,074...21,115,869
Ensembl chrNW_004624754:21,108,874...21,115,885
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Cenpb
centromere protein B
ISO
RGD
PMID:8911074
RGD:27226708
NCBI chrNW_004624741:4,868,453...4,870,933
Ensembl chrNW_004624741:4,869,248...4,870,897
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Clec16a
C-type lectin domain containing 16A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21399635
NCBI chrNW_004624824:8,174,653...8,400,760
Ensembl chrNW_004624824:8,174,610...8,400,723
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Col1a1
collagen type I alpha 1 chain
treatment
ISO
RGD
PMID:20056896
RGD:8552731
NCBI chrNW_004624795:6,167,504...6,183,208
Ensembl chrNW_004624795:6,168,797...6,183,071
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Cpeb1
cytoplasmic polyadenylation element binding protein 1
ISO
protein:increased expression:liver
RGD
PMID:26627607
RGD:11528851
NCBI chrNW_004624768:18,386,415...18,468,879
G
Cpeb4
cytoplasmic polyadenylation element binding protein 4
ISO
protein:increased expression:liver
RGD
PMID:26627607
RGD:11528851
NCBI chrNW_004624733:16,082,461...16,146,798
Ensembl chrNW_004624733:16,082,369...16,147,075
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Ctla4
cytotoxic T-lymphocyte associated protein 4
susceptibility disease_progression no_association
ISO
autoimmune biliary cirrhosis; DNA:SNP:CDS:49A>G, significant association with G allele (p<0.0002) DNA:SNP:CDS:60G>A(rs3087243)(human) DNA:SNPs: :rs231775, rs3087243, rs231725 (human) DNA:SNP:CDS:49A>G(human)
RGD
PMID:10782900 PMID:16584111 PMID:17482523 PMID:21594562
RGD:14398725 RGD:14398743 RGD:14398744 RGD:2301998
NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324
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Cxcl10
C-X-C motif chemokine ligand 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18422935
NCBI chrNW_004624757:14,989,241...14,991,650
Ensembl chrNW_004624757:14,989,084...14,991,910
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Cxcl8
C-X-C motif chemokine ligand 8
ISO
mRNA:increased expression:liver (human)
RGD
PMID:21731723
RGD:26884357
NCBI chrNW_004624730:1,744,097...1,747,206
Ensembl chrNW_004624730:1,743,916...1,747,293
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Cxcl9
C-X-C motif chemokine ligand 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18422935
NCBI chrNW_004624757:14,995,649...15,009,771
Ensembl chrNW_004624757:14,995,716...15,011,893
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Cxcr5
C-X-C motif chemokine receptor 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21399635
NCBI chrNW_004624784:14,285,998...14,298,679
Ensembl chrNW_004624784:14,286,355...14,297,383
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Cygb
cytoglobin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30026087
NCBI chrNW_004624801:6,385,771...6,395,705
Ensembl chrNW_004624801:6,384,213...6,395,979
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Dag1
dystroglycan 1
ISO
mRNA:increased expression:liver
RGD
PMID:12177244
RGD:2314895
NCBI chrNW_004624730:3,417,356...3,488,300
Ensembl chrNW_004624730:3,417,347...3,488,879
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Dennd1b
DENN domain containing 1B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21399635
NCBI chrNW_004624798:2,621,604...2,844,370
Ensembl chrNW_004624798:2,622,379...2,838,775
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Dnase1
deoxyribonuclease 1
ISO
protein:decreased activity:serum (human)
RGD
PMID:28263100
RGD:38500241
NCBI chrNW_004624824:1,429,078...1,446,881
Ensembl chrNW_004624824:1,443,451...1,446,881
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Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:15651265
RGD:9685530
NCBI chrNW_004624760:859,598...865,194
Ensembl chrNW_004624760:859,637...866,804
G
Fas
Fas cell surface death receptor
ISO
protein:increased expression:lymphocyte:
RGD
PMID:26429926
RGD:14700711
NCBI chrNW_004624791:15,290,022...15,315,848
Ensembl chrNW_004624791:15,289,348...15,315,848
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Foxp3
forkhead box P3
ISO
mRNA:increased expression:liver
RGD
PMID:17158635
RGD:38501106
NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679
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Gch1
GTP cyclohydrolase 1
treatment
ISO
RGD
PMID:20132096
RGD:329970291
NCBI chrNW_004624731:14,459,164...14,502,485
Ensembl chrNW_004624731:14,459,303...14,500,429
G
Hamp
hepcidin antimicrobial peptide
treatment
ISO
mRNA:decreased expression:liver
RGD
PMID:19652645 PMID:23704825
RGD:11041639 RGD:11041732
NCBI chrNW_004624794:8,257,760...8,259,243
Ensembl chrNW_004624794:8,257,760...8,259,264
G
Hhip
hedgehog interacting protein
ISO
mRNA:decreased expression:
RGD
PMID:18375471
RGD:11552599
NCBI chrNW_004624853:3,649,974...3,739,344
Ensembl chrNW_004624853:3,649,967...3,735,834
G
Hif1a
hypoxia inducible factor 1 subunit alpha
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22271822
NCBI chrNW_004624734:39,414,458...39,471,705
Ensembl chrNW_004624734:39,411,824...39,471,705
G
Hmox1
heme oxygenase 1
ISO
mRNA, protein:increased expression:liver, lung
RGD
PMID:12114196
RGD:625603
NCBI chrNW_004624750:341,699...346,005
Ensembl chrNW_004624750:342,146...345,887
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Icam1
intercellular adhesion molecule 1
treatment
ISO
associated with Graft vs Host Disease;
RGD
PMID:10051478
RGD:11520783
NCBI chrNW_004624828:2,432,584...2,451,997
Ensembl chrNW_004624828:2,432,550...2,453,071
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Ifng
interferon gamma
ISO
mRNA:increased expression:liver
RGD
PMID:17158635
RGD:38501106
NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534
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Igfbp1
insulin like growth factor binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18422935
NCBI chrNW_004624740:6,893,334...6,897,591
Ensembl chrNW_004624740:6,893,867...6,897,377
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Il10
interleukin 10
ISO
mRNA:increased expression:liver
RGD
PMID:17158635
RGD:38501106
NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732
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Il12a
interleukin 12A
treatment susceptibility
ISO
DNA:SNP: :rs62270414(human) CTD Direct Evidence: marker/mechanism DNA:SNPs:enhancer:rs4679868, rs6441286, rs666251(human) DNA:SNPs, haplotype: :rs6441286, rs574808(human)
RGD CTD
PMID:19458352 PMID:20639880 PMID:23433321 PMID:27175695
RGD:25440489 RGD:25440498 RGD:25440500
NCBI chrNW_004624730:37,787,772...37,794,871
Ensembl chrNW_004624730:37,787,909...37,794,940
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Il12b
interleukin 12B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20639880
NCBI chrNW_004624733:30,146,050...30,156,144
Ensembl chrNW_004624733:30,146,050...30,154,589
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Il12rb1
interleukin 12 receptor subunit beta 1
susceptibility
ISO
RNA:increased expression:peripheral blood mononuclear cell (human)
RGD
PMID:23910013
RGD:14700865
NCBI chrNW_004624908:1,472,059...1,481,423
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Il1b
interleukin 1 beta
disease_progression
ISO
protein:increased expression:blood serum (human)
RGD
PMID:21275501
RGD:407420272
NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760
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Il4
interleukin 4
treatment
ISO
RGD
PMID:20442198
RGD:7829828
NCBI chrNW_004624733:39,412,800...39,420,079
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Il6
interleukin 6
disease_progression
ISO
protein:increased expression:blood serum (human)
RGD
PMID:21275501
RGD:407420272
NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318
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Il7r
interleukin 7 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21399635
NCBI chrNW_004624759:19,067,933...19,103,007
Ensembl chrNW_004624759:19,067,856...19,098,859
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Jak2
Janus kinase 2
treatment
ISO
RGD
PMID:24619965
RGD:10403061
NCBI chrNW_004624736:9,724,876...9,827,364
Ensembl chrNW_004624736:9,724,369...9,830,365
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Keap1
kelch like ECH associated protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30026087
NCBI chrNW_004624828:2,580,812...2,595,023
Ensembl chrNW_004624828:2,580,861...2,595,275
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Krt18
keratin 18
severity
ISO
protein:increased expression:serum (human)
RGD
PMID:26110613
RGD:18337483
NCBI chrNW_004624904:1,011,675...1,015,319
Ensembl chrNW_004624904:1,011,755...1,015,416
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Krt7
keratin 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21681009
NCBI chrNW_004624816:103,285...168,486
Ensembl chrNW_004624816:105,758...134,567
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Lbr
lamin B receptor
ISO
RGD
PMID:8550049
RGD:9588625
NCBI chrNW_004624835:6,469,677...6,489,790
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Lep
leptin
ISO
protein:decreased expression:serum:
RGD
PMID:16093869
RGD:10411894
NCBI chrNW_004624783:7,708,820...7,721,610
Ensembl chrNW_004624783:7,708,588...7,721,727
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Lepr
leptin receptor
ISO
protein:increased expression:blood serum
RGD
PMID:16093869
RGD:10411894
NCBI chrNW_004624742:29,221,742...29,313,273
Ensembl chrNW_004624742:29,223,392...29,337,049
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Lox
lysyl oxidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16023247
NCBI chrNW_004624774:20,116,625...20,137,767
Ensembl chrNW_004624774:20,116,970...20,134,355
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Loxl2
lysyl oxidase like 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16023247
NCBI chrNW_004624758:18,567,367...18,644,528
Ensembl chrNW_004624758:18,568,607...18,621,785
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Map3k14
mitogen-activated protein kinase kinase kinase 14
ISO
OMIM:109720 | OMIM:613007 | OMIM:613008 | OMIM:614220 | OMIM:614221
MouseDO
NCBI chrNW_004624795:167,959...207,421
Ensembl chrNW_004624795:167,990...203,784
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Mapk14
mitogen-activated protein kinase 14
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30026087
NCBI chrNW_004624754:21,528,121...21,598,064
Ensembl chrNW_004624754:21,527,333...21,597,733
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Mas1
MAS1 proto-oncogene, G protein-coupled receptor
ISO
RGD
PMID:17532087
RGD:9685452
NCBI chrNW_004624855:2,968,111...3,008,728
Ensembl chrNW_004624855:2,969,444...2,970,421
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Met
MET proto-oncogene, receptor tyrosine kinase
severity
ISO
RGD
PMID:19208365
RGD:14694826
NCBI chrNW_004624827:2,589,157...2,724,065
Ensembl chrNW_004624827:2,587,966...2,723,995
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Mmel1
membrane metalloendopeptidase like 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20639879
NCBI chrNW_004624818:7,451,213...7,481,988
Ensembl chrNW_004624818:7,453,177...7,485,439
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Mmp13
matrix metallopeptidase 13
treatment
ISO
RGD
PMID:20056896
RGD:8552731
NCBI chrNW_004624918:2,228,688...2,239,852
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Mmp2
matrix metallopeptidase 2
treatment
ISO
RGD
PMID:20056896
RGD:8552731
NCBI chrNW_004624757:1,450,680...1,479,160
Ensembl chrNW_004624757:1,448,698...1,479,255
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Mmp3
matrix metallopeptidase 3
treatment
ISO
RGD
PMID:20056896
RGD:8552731
NCBI chrNW_004624878:39,282...47,386
Ensembl chrNW_004624878:39,358...47,075
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Mmp9
matrix metallopeptidase 9
treatment
ISO
RGD
PMID:20056896
RGD:8552731
NCBI chrNW_004624790:8,584,399...8,591,763
Ensembl chrNW_004624790:8,583,457...8,591,713
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Muc2
mucin 2, oligomeric mucus/gel-forming
ISO
RGD
PMID:18507686
RGD:2324885
NCBI chrNW_004624766:21,493,125...21,522,535
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Nfe2l2
NFE2 like bZIP transcription factor 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30026087
NCBI chrNW_004624787:14,355,330...14,381,353
Ensembl chrNW_004624787:14,355,791...14,381,251
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Nfkb1
nuclear factor kappa B subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21399635
NCBI chrNW_004624830:5,334,273...5,430,887
Ensembl chrNW_004624830:5,333,616...5,408,723
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Nos2
nitric oxide synthase 2
ISO
protein:increased expression, increased activity:brain (rat) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:21903766 PMID:30026087
RGD:5509055
NCBI chrNW_004624786:491,944...530,427
Ensembl chrNW_004624786:489,311...528,271
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Nos3
nitric oxide synthase 3
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:20132096 PMID:30026087
RGD:329970291
NCBI chrNW_004624800:5,600,215...5,619,020
Ensembl chrNW_004624800:5,600,212...5,619,004
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Nr1h4
nuclear receptor subfamily 1 group H member 4
susceptibility
ISO
mRNA,protein:decreased expression:liver (human)
RGD
PMID:29968724
RGD:14928336
NCBI chrNW_004624750:7,222,306...7,303,809
Ensembl chrNW_004624750:7,219,251...7,303,834
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Nr3c1
nuclear receptor subfamily 3 group C member 1
ISO
mRNA:altered expression:leukocyte, mononuclear
RGD
PMID:15635817
RGD:4892607
NCBI chrNW_004624774:2,496,276...2,603,894
Ensembl chrNW_004624774:2,495,304...2,602,632
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Nsa2
NSA2 ribosome biogenesis factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18422935
NCBI chrNW_004624924:135,222...142,350
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Nup62
nucleoporin 62
severity
ISO
RGD
PMID:12753810
RGD:9831196
NCBI chrNW_004624832:4,404,367...4,428,231
Ensembl chrNW_004624832:4,404,245...4,428,231
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Pde5a
phosphodiesterase 5A
ISO
RGD
PMID:17610866
RGD:2314466
NCBI chrNW_004624964:11,085...126,027
Ensembl chrNW_004624964:14,216...126,553
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Ppargc1a
PPARG coactivator 1 alpha
ISO
mRNA, protein:decreased expression:liver
RGD
NCBI chrNW_004624755:7,826,219...8,460,746
Ensembl chrNW_004624755:8,375,596...8,465,297
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Rela
RELA proto-oncogene, NF-kB subunit
disease_progression
ISO
CTD Direct Evidence: marker/mechanism protein:increased expression:liver (human)
CTD RGD
PMID:21275501 PMID:30026087
RGD:407420272
NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272
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Ren
renin
ISO
protein:increased activity:plasma (rat)
RGD
PMID:22266601
RGD:6892690
NCBI chrNW_004624807:6,817,472...6,827,374
Ensembl chrNW_004624807:6,817,195...6,827,462
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Rps6kb1
ribosomal protein S6 kinase B1
ISO
protein:increased expression, increased phosphorylation:liver
RGD
PMID:15769867
RGD:1642977
NCBI chrNW_004624871:1,667,292...1,705,550
Ensembl chrNW_004624871:1,667,291...1,702,783
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Slc4a2
solute carrier family 4 member 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18188457
NCBI chrNW_004624800:5,545,380...5,560,789
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Slc51a
solute carrier family 51 member A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16423920
NCBI chrNW_004624730:61,405,480...61,416,602
Ensembl chrNW_004624730:61,404,807...61,416,384
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Slco1c1
solute carrier organic anion transporter family member 1C1
ISO
protein:decreased expression:liver
RGD
PMID:15770136
RGD:14700810
NCBI chrNW_004624752:17,718,696...17,765,705
Ensembl chrNW_004624752:17,720,716...17,765,561
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Sod2
superoxide dismutase 2
ISO
protein:increased expression:serum
RGD
PMID:1682406
RGD:2317411
NCBI chrNW_004624855:3,260,800...3,271,864
Ensembl chrNW_004624855:3,260,809...3,271,367
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Spib
Spi-B transcription factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20639880
NCBI chrNW_004624832:4,110,462...4,116,657
Ensembl chrNW_004624832:4,111,939...4,116,657
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Spint1
serine peptidase inhibitor, Kunitz type 1
ISO
mRNA:increased expression:liver:
RGD
PMID:21898507
RGD:10043111
NCBI chrNW_004624804:8,092,700...8,105,478
Ensembl chrNW_004624804:8,093,346...8,106,193
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Spint2
serine peptidase inhibitor, Kunitz type 2
ISO
mRNA:increased expression:liver:
RGD
PMID:21898507
RGD:10043111
NCBI chrNW_004624794:11,738,137...11,765,579
Ensembl chrNW_004624794:11,738,487...11,769,117
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Stat4
signal transducer and activator of transcription 4
no_association susceptibility
ISO
DNA:SNPs:3'utr: (rs7574865, rs8179673, rs10181656) (human) associated with Crohn���s disease; DNA:SNP:intron: (rs7574865) (human) DNA:SNP: intron: (rs7574865) (human) DNA:SNPs, haplotypes:multiple CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:21399635 PMID:24648611 PMID:26084578 PMID:28395724
RGD:25671415 RGD:25671416 RGD:25671421
NCBI chrNW_004624854:4,975,724...5,056,940
Ensembl chrNW_004624854:4,976,507...5,057,391
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Tgfb1
transforming growth factor beta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30026087
NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605
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Tjp2
tight junction protein 2
ISO
ClinVar Annotator: match by term: Primary biliary cirrhosis
ClinVar
PMID:25741868 PMID:28492532 PMID:32439973
NCBI chrNW_004624736:3,833,402...4,009,385
Ensembl chrNW_004624736:3,834,548...3,878,828
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Tnf
tumor necrosis factor
disease_progression
ISO
protein:increased expression:serum (human) protein:increased expression:blood serum(human) mRNA:increased expression:liver
RGD
PMID:9047083 PMID:17158635 PMID:21275501
RGD:14995307 RGD:38501106 RGD:407420272
NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531
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Tnfrsf1a
TNF receptor superfamily member 1A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21399635
NCBI chrNW_004624860:3,111,244...3,123,041
Ensembl chrNW_004624860:3,111,630...3,122,711
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Tyk2
tyrosine kinase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22961000
NCBI chrNW_004624828:2,499,811...2,518,817
Ensembl chrNW_004624828:2,500,339...2,517,694
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Utp4
UTP4 small subunit processome component
ISO
North American Indian childhood cirrhosis, OMIM:604901, R565W
RGD
PMID:12417987
RGD:1600653
NCBI chrNW_004624746:17,176,390...17,205,960
Ensembl chrNW_004624746:17,172,124...17,206,262
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Vdr
vitamin D receptor
susceptibility
ISO
DNA:polymorphism: : DNA:SNP: :
RGD
PMID:15683428 PMID:19376604
RGD:14401750 RGD:14402024
NCBI chrNW_004624816:4,314,146...4,423,946
Ensembl chrNW_004624816:4,365,961...4,424,514
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Vegfa
vascular endothelial growth factor A
ISO
protein:increased expression:liver protein:increased expression:plasma:
RGD
PMID:26615570 PMID:26627607
RGD:11528851 RGD:11538286
NCBI chrNW_004624754:15,929,414...15,943,637
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Zc3h12a
zinc finger CCCH-type containing 12A
ISO
OMIM:109720 | OMIM:613007 | OMIM:613008 | OMIM:614220 | OMIM:614221
MouseDO
NCBI chrNW_004624764:20,224,919...20,234,108
Ensembl chrNW_004624764:20,224,906...20,234,629
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Il12rb2
interleukin 12 receptor subunit beta 2
ISO
ClinVar Annotator: match by term: IL12RB2-related condition
ClinVar
PMID:25741868 PMID:28492532
NCBI chrNW_004624742:27,830,691...27,865,176
Ensembl chrNW_004624742:27,832,883...27,865,139
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Lbr
lamin B receptor
ISO
ClinVar Annotator: match by term: PRIMARY BILIARY CIRRHOSIS, SCLERODERMA, RAYNAUD DISEASE, AND TELANGIECTASIA | ClinVar Annotator: match by term: Reynolds syndrome
OMIM ClinVar
PMID:18382993 PMID:20522425 PMID:24033266 PMID:25348816 PMID:25741868 PMID:26467025 PMID:28492532 PMID:32827848 More...
NCBI chrNW_004624835:6,469,677...6,489,790
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