Kmo (kynurenine 3-monooxygenase) - Rat Genome Database

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Gene: Kmo (kynurenine 3-monooxygenase) Heterocephalus glaber
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Symbol: Kmo
Name: kynurenine 3-monooxygenase
RGD ID: 18918093
Description: ENCODES a protein that exhibits kynurenine 3-monooxygenase activity (ortholog); NAD(P)H oxidase H2O2-forming activity (ortholog); INVOLVED IN cellular response to interleukin-1 (ortholog); cellular response to lipopolysaccharide (ortholog); kynurenic acid biosynthetic process (ortholog); PARTICIPATES IN kynurenine metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH Acute Experimental Pancreatitis (ortholog); allergic contact dermatitis (ortholog); depressive disorder (ortholog); FOUND IN extracellular space (ortholog); mitochondrial outer membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477111,899,624 - 11,942,806 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477111,900,020 - 11,942,943 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kmo
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477111,899,624 - 11,942,806 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477111,900,020 - 11,942,943 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KMO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381241,532,378 - 241,595,642 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1241,532,134 - 241,595,642 (+)EnsemblGRCh38hg38GRCh38
GRCh371241,695,678 - 241,758,944 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361239,762,330 - 239,825,566 (+)NCBINCBI36Build 36hg18NCBI36
Build 341238,021,747 - 238,084,984NCBI
Celera1214,950,683 - 215,013,947 (+)NCBICelera
Cytogenetic Map1q43NCBI
HuRef1212,153,669 - 212,217,265 (+)NCBIHuRef
CHM1_11242,968,145 - 243,031,623 (+)NCBICHM1_1
T2T-CHM13v2.01240,943,769 - 241,007,043 (+)NCBIT2T-CHM13v2.0
Kmo
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,459,759 - 175,488,419 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,447,947 - 175,489,682 (+)EnsemblGRCm39 Ensembl
GRCm381175,632,193 - 175,660,853 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,620,381 - 175,662,116 (+)EnsemblGRCm38mm10GRCm38
MGSCv371177,562,324 - 177,590,984 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361177,468,868 - 177,497,528 (+)NCBIMGSCv36mm8
Celera1182,717,886 - 182,746,514 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map181.6NCBI
Kmo
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81390,089,340 - 90,121,108 (+)NCBIGRCr8
mRatBN7.21387,557,080 - 87,589,334 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1387,557,286 - 87,588,881 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1390,057,159 - 90,088,772 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01391,457,419 - 91,489,032 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01388,636,585 - 88,668,179 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01393,684,324 - 93,715,378 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1393,684,437 - 93,716,227 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01398,149,340 - 98,180,255 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41391,363,517 - 91,394,174 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11391,552,400 - 91,583,055 (+)NCBI
Celera1387,155,915 - 87,185,730 (+)NCBICelera
Cytogenetic Map13q24NCBI
Kmo
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540610,493,379 - 10,527,201 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540610,496,102 - 10,527,181 (-)NCBIChiLan1.0ChiLan1.0
KMO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v217,552,637 - 7,615,066 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117,775,244 - 7,838,816 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01217,094,037 - 217,157,827 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11222,075,577 - 222,138,866 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1222,075,268 - 222,138,866 (+)Ensemblpanpan1.1panPan2
KMO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1732,941,487 - 32,994,541 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl732,941,487 - 32,994,541 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha732,419,026 - 32,472,013 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0732,767,900 - 32,821,021 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl732,767,900 - 32,821,021 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1732,602,997 - 32,656,010 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0732,627,134 - 32,680,135 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0732,875,278 - 32,928,138 (+)NCBIUU_Cfam_GSD_1.0
Kmo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934445,818,797 - 45,870,212 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365268,877,434 - 8,919,548 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365268,877,085 - 8,928,280 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KMO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1012,442,645 - 12,490,409 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11012,442,877 - 12,489,417 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21014,879,142 - 14,937,353 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KMO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12578,611,194 - 78,670,314 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2578,628,757 - 78,670,181 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605580,745,055 - 80,803,000 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000014531   ⟹   ENSHGLP00000014387
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477111,899,624 - 11,942,806 (+)Ensembl
RefSeq Acc Id: XM_013075317   ⟹   XP_012930771
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,900,020 - 11,942,943 (+)NCBI
RefSeq Acc Id: XM_021265483   ⟹   XP_021121142
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,900,026 - 11,942,943 (+)NCBI
RefSeq Acc Id: XM_021265484   ⟹   XP_021121143
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477111,900,021 - 11,942,943 (+)NCBI
Protein Sequences
Protein RefSeqs XP_012930771 (Get FASTA)   NCBI Sequence Viewer  
  XP_021121142 (Get FASTA)   NCBI Sequence Viewer  
  XP_021121143 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB09989 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014387
  ENSHGLP00000035591
GenBank Protein JAO01152 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_012930771   ⟸   XM_013075317
- Peptide Label: isoform X1
- UniProtKB: G5BL28 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121143   ⟸   XM_021265484
- Peptide Label: isoform X3
- UniProtKB: A0AAX6TJR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021121142   ⟸   XM_021265483
- Peptide Label: isoform X2
- UniProtKB: A0AAX6TFG3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000014387   ⟸   ENSHGLT00000014531


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010301 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000014531 ENTREZGENE
  ENSHGLT00000071161 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/TrEMBL
InterPro FAD-bd UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/TrEMBL
  Kynurenine_monooxygenase UniProtKB/TrEMBL
NCBI Gene Kmo ENTREZGENE
PANTHER KYNURENINE 3-MONOOXYGENASE UniProtKB/TrEMBL
  KYNURENINE 3-MONOOXYGENASE UniProtKB/TrEMBL
Pfam FAD_binding_3 UniProtKB/TrEMBL
PRINTS RNGMNOXGNASE UniProtKB/TrEMBL
Superfamily-SCOP SSF51905 UniProtKB/TrEMBL
UniProt A0AAX6TFG3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TJR5 ENTREZGENE, UniProtKB/TrEMBL
  G5BL28 ENTREZGENE, UniProtKB/TrEMBL