Nfkbie (NFKB inhibitor epsilon) - Rat Genome Database

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Gene: Nfkbie (NFKB inhibitor epsilon) Heterocephalus glaber
Analyze
Symbol: Nfkbie
Name: NFKB inhibitor epsilon
RGD ID: 18914122
Description: ENCODES a protein that exhibits NF-kappaB binding (inferred); INVOLVED IN D-serine transmembrane transport (ortholog); PARTICIPATES IN nuclear factor kappa B signaling pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); melanoma (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NF-kappa-B inhibitor epsilon
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475415,593,765 - 15,605,788 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475415,593,755 - 15,605,998 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nfkbie
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475415,593,765 - 15,605,788 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475415,593,755 - 15,605,998 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NFKBIE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38644,258,166 - 44,265,551 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl644,258,166 - 44,265,788 (-)EnsemblGRCh38hg38GRCh38
GRCh37644,225,903 - 44,233,288 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36644,333,881 - 44,341,503 (-)NCBINCBI36Build 36hg18NCBI36
Build 34644,334,404 - 44,341,503NCBI
Celera645,779,052 - 45,786,678 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef643,947,918 - 43,955,542 (-)NCBIHuRef
CHM1_1644,229,610 - 44,237,246 (-)NCBICHM1_1
T2T-CHM13v2.0644,092,317 - 44,099,688 (-)NCBIT2T-CHM13v2.0
Nfkbie
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391745,866,626 - 45,874,095 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1745,866,629 - 45,874,095 (+)EnsemblGRCm39 Ensembl
GRCm381745,555,700 - 45,563,169 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,555,703 - 45,563,169 (+)EnsemblGRCm38mm10GRCm38
MGSCv371745,692,665 - 45,700,118 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361745,019,297 - 45,026,750 (+)NCBIMGSCv36mm8
Celera1748,988,415 - 48,995,813 (+)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1722.58NCBI
Nfkbie
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8922,941,037 - 22,947,872 (-)NCBIGRCr8
mRatBN7.2915,443,600 - 15,450,437 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl915,436,941 - 15,450,437 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx924,030,126 - 24,036,913 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0929,092,803 - 29,099,590 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0927,393,565 - 27,400,352 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,828,405 - 17,835,240 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,828,408 - 17,835,240 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,717,126 - 16,723,961 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4911,044,112 - 11,050,948 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1911,041,436 - 11,048,270 (-)NCBI
Celera913,186,838 - 13,193,673 (-)NCBICelera
Cytogenetic Map9q12NCBI
Nfkbie
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,882,460 - 9,888,952 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,882,460 - 9,888,848 (-)NCBIChiLan1.0ChiLan1.0
NFKBIE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,762,193 - 58,772,393 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,632,285 - 54,642,475 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,853,921 - 43,861,686 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1645,137,160 - 45,144,699 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl645,138,209 - 45,144,680 (-)Ensemblpanpan1.1panPan2
NFKBIE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,668,664 - 12,674,146 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,694,054 - 12,702,366 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01213,151,713 - 13,160,030 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1213,151,717 - 13,160,137 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,677,143 - 12,685,399 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,764,624 - 12,772,929 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,858,827 - 12,867,147 (-)NCBIUU_Cfam_GSD_1.0
Nfkbie
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494648,134,122 - 48,141,644 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647615,818,554 - 15,826,327 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647615,818,605 - 15,825,558 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFKBIE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl739,255,075 - 39,263,339 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1739,255,078 - 39,266,085 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2745,124,531 - 45,133,184 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NFKBIE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11727,901,990 - 27,909,983 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1727,902,389 - 27,910,440 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604444,312,243 - 44,319,949 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000018023   ⟹   ENSHGLP00000017846
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475415,593,765 - 15,605,788 (+)Ensembl
RefSeq Acc Id: XM_004846448   ⟹   XP_004846505
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475415,593,953 - 15,605,998 (+)NCBI
RefSeq Acc Id: XM_004846450   ⟹   XP_004846507
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475415,593,755 - 15,605,998 (+)NCBI
RefSeq Acc Id: XM_004846451   ⟹   XP_004846508
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475415,593,965 - 15,605,998 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004846505 (Get FASTA)   NCBI Sequence Viewer  
  XP_004846507 (Get FASTA)   NCBI Sequence Viewer  
  XP_004846508 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10886 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017846
  ENSHGLP00100014936
Reference Protein Sequences
RefSeq Acc Id: XP_004846507   ⟸   XM_004846450
- Peptide Label: isoform X1
- UniProtKB: G5BNP0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004846505   ⟸   XM_004846448
- Peptide Label: isoform X1
- UniProtKB: G5BNP0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004846508   ⟸   XM_004846451
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000017846   ⟸   ENSHGLT00000018023


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012781 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100011062 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000018023 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00100015101 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
KEGG Report hgl:101697721 UniProtKB/TrEMBL
NCBI Gene Nfkbie ENTREZGENE
PANTHER NF-KAPPA-B INHIBITOR ALPHA UniProtKB/TrEMBL
  NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt G5BNP0 ENTREZGENE, UniProtKB/TrEMBL