Spint2 (serine peptidase inhibitor, Kunitz type 2) - Rat Genome Database

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Gene: Spint2 (serine peptidase inhibitor, Kunitz type 2) Heterocephalus glaber
Analyze
Symbol: Spint2
Name: serine peptidase inhibitor, Kunitz type 2
RGD ID: 18924240
Description: ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN basement membrane organization (ortholog); cellular response to BMP stimulus (ortholog); epithelial cell morphogenesis involved in placental branching (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); biliary atresia (ortholog); carcinoma (ortholog); FOUND IN cytoplasm (ortholog); Golgi apparatus (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kunitz-type protease inhibitor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479411,738,487 - 11,769,117 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479411,738,137 - 11,765,579 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Spint2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479411,738,487 - 11,769,117 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479411,738,137 - 11,765,579 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SPINT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381938,264,573 - 38,292,615 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1938,244,035 - 38,292,615 (+)EnsemblGRCh38hg38GRCh38
GRCh371938,755,213 - 38,783,255 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361943,447,042 - 43,474,948 (+)NCBINCBI36Build 36hg18NCBI36
Build 341943,447,041 - 43,474,948NCBI
Celera1935,557,341 - 35,585,496 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1935,203,084 - 35,231,226 (+)NCBIHuRef
CHM1_11938,755,457 - 38,783,611 (+)NCBICHM1_1
T2T-CHM13v2.01941,066,744 - 41,094,785 (+)NCBIT2T-CHM13v2.0
Spint2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39728,955,755 - 28,981,484 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl728,955,748 - 28,981,337 (-)EnsemblGRCm39 Ensembl
GRCm38729,256,330 - 29,282,059 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl729,256,323 - 29,281,912 (-)EnsemblGRCm38mm10GRCm38
MGSCv37730,041,349 - 30,066,996 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36728,962,340 - 28,990,672 (-)NCBIMGSCv36mm8
Celera723,827,594 - 23,853,242 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map716.94NCBI
Spint2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8193,685,637 - 93,708,091 (-)NCBIGRCr8
mRatBN7.2184,558,159 - 84,580,616 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl184,558,166 - 84,580,616 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx189,969,614 - 89,992,076 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0198,429,257 - 98,452,000 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0191,725,462 - 91,747,920 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0187,199,373 - 87,221,826 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl187,199,313 - 87,221,892 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0188,379,991 - 88,402,444 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4184,393,845 - 84,416,299 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1184,471,959 - 84,494,410 (-)NCBI
Celera178,945,340 - 78,967,783 (-)NCBICelera
Cytogenetic Map1q21NCBI
Spint2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554681,143,118 - 1,169,632 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554681,142,718 - 1,181,210 (-)NCBIChiLan1.0ChiLan1.0
SPINT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22044,550,481 - 44,581,135 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11946,421,471 - 46,451,498 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01935,354,043 - 35,384,063 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11943,928,847 - 43,958,886 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1943,928,847 - 43,958,886 (+)Ensemblpanpan1.1panPan2
SPINT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11114,699,050 - 114,727,802 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1114,699,241 - 114,727,763 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1114,102,476 - 114,131,030 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01115,300,913 - 115,329,535 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1115,300,927 - 115,329,591 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11114,873,736 - 114,902,272 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01114,491,884 - 114,520,398 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01115,530,220 - 115,559,152 (-)NCBIUU_Cfam_GSD_1.0
Spint2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934912,876,574 - 12,904,236 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368011,041,708 - 1,069,776 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049368011,041,946 - 1,069,617 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPINT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl647,181,768 - 47,210,559 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1647,181,772 - 47,210,564 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2642,682,276 - 42,710,782 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPINT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1632,902,336 - 32,935,681 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl632,902,946 - 32,939,136 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607310,846,319 - 10,880,946 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000024749   ⟹   ENSHGLP00000024528
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479411,738,487 - 11,769,117 (+)Ensembl
RefSeq Acc Id: XM_004859037   ⟹   XP_004859094
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479411,738,137 - 11,765,579 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004859094 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024528
GenBank Protein JAN96261 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004859094   ⟸   XM_004859037
- UniProtKB: A0A0N8ESE9 (UniProtKB/TrEMBL),   G5AMC2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000024528   ⟸   ENSHGLT00000024749


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017481 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000024749 ENTREZGENE
Gene3D-CATH 4.10.410.10 UniProtKB/TrEMBL
InterPro Kunitz_BPTI UniProtKB/TrEMBL
  Kunitz_BPTI_sf UniProtKB/TrEMBL
  Prtase_inh_Kunz-CS UniProtKB/TrEMBL
KEGG Report hgl:101704151 UniProtKB/TrEMBL
NCBI Gene Spint2 ENTREZGENE
PANTHER KUNITZ-TYPE PROTEASE INHIBITOR 2 UniProtKB/TrEMBL
  KUNITZ-TYPE PROTEASE INHIBITOR 2 UniProtKB/TrEMBL
Pfam Kunitz_BPTI UniProtKB/TrEMBL
PRINTS BASICPTASE UniProtKB/TrEMBL
PROSITE BPTI_KUNITZ_1 UniProtKB/TrEMBL
  BPTI_KUNITZ_2 UniProtKB/TrEMBL
SMART SM00131 UniProtKB/TrEMBL
Superfamily-SCOP SSF57362 UniProtKB/TrEMBL
UniProt A0A0N8ESE9 ENTREZGENE, UniProtKB/TrEMBL
  G5AMC2 ENTREZGENE, UniProtKB/TrEMBL