Mro (maestro) - Rat Genome Database

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Gene: Mro (maestro) Heterocephalus glaber
Analyze
Symbol: Mro
Name: maestro
RGD ID: 18906119
Description: ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); intellectual disability (ortholog); FOUND IN nucleolus (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein maestro
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477814,352,856 - 14,359,678 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477814,352,071 - 14,359,861 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleolus  (ISO)
nucleus  (ISO)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Mro
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477814,352,856 - 14,359,678 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477814,352,071 - 14,359,861 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MRO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381850,795,130 - 50,825,380 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1850,795,120 - 50,825,402 (-)EnsemblGRCh38hg38GRCh38
GRCh371848,321,500 - 48,351,750 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361846,578,572 - 46,600,366 (-)NCBINCBI36Build 36hg18NCBI36
Build 341846,578,571 - 46,600,366NCBI
Celera1845,178,236 - 45,208,500 (-)NCBICelera
Cytogenetic Map18q21.2NCBI
HuRef1845,176,072 - 45,207,050 (-)NCBIHuRef
CHM1_11848,316,965 - 48,347,220 (-)NCBICHM1_1
T2T-CHM13v2.01850,996,813 - 51,027,082 (-)NCBIT2T-CHM13v2.0
Mro
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391873,992,465 - 74,014,405 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1873,992,456 - 74,014,404 (+)EnsemblGRCm39 Ensembl
GRCm381873,851,826 - 73,881,334 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1873,859,385 - 73,881,333 (+)EnsemblGRCm38mm10GRCm38
MGSCv371874,019,041 - 74,038,788 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361873,984,754 - 74,004,099 (+)NCBIMGSCv36mm8
Celera1875,097,045 - 75,113,615 (+)NCBICelera
Cytogenetic Map18E2NCBI
cM Map1850.21NCBI
Mro
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81869,723,764 - 69,742,815 (+)NCBIGRCr8
mRatBN7.21867,450,186 - 67,467,593 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1867,450,595 - 67,467,044 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01869,833,770 - 69,850,164 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1869,841,053 - 69,849,389 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01868,977,912 - 68,993,961 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41870,648,892 - 70,660,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1865,628,703 - 65,650,686 (+)NCBICelera
Cytogenetic Map18q12.2NCBI
Mro
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540235,745,692 - 35,765,887 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540235,745,823 - 35,765,507 (-)NCBIChiLan1.0ChiLan1.0
MRO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21768,319,472 - 68,344,255 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11854,012,076 - 54,036,831 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01844,172,007 - 44,202,095 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11847,518,586 - 47,548,647 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1847,522,590 - 47,543,216 (-)Ensemblpanpan1.1panPan2
MRO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1124,073,130 - 24,093,325 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl124,072,415 - 24,088,798 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0123,964,754 - 23,984,902 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl123,964,598 - 23,980,855 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1124,025,195 - 24,045,719 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0123,911,569 - 23,932,073 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0124,184,791 - 24,205,241 (+)NCBIUU_Cfam_GSD_1.0
Mro
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494437,225,208 - 37,243,326 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649712,468,810 - 12,484,070 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649712,468,839 - 12,482,645 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1100,343,462 - 100,368,354 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11100,342,040 - 100,368,355 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21110,207,703 - 110,217,351 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MRO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11830,149,163 - 30,177,547 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1830,166,834 - 30,181,570 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660504,280,138 - 4,312,863 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021236627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01057020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000020613   ⟹   ENSHGLP00000020411
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477814,352,856 - 14,359,678 (-)Ensembl
RefSeq Acc Id: XM_021236627   ⟹   XP_021092286
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477814,352,071 - 14,359,861 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021092286 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020411
RefSeq Acc Id: XP_021092286   ⟸   XM_021236627
- UniProtKB: A0AAX6R5W3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000020411   ⟸   ENSHGLT00000020613


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014593 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000020613 ENTREZGENE
Gene3D-CATH Leucine-rich Repeat Variant UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Maestro_heat-like_prot UniProtKB/TrEMBL
  Maestro_HEAT_rpt UniProtKB/TrEMBL
NCBI Gene Mro ENTREZGENE
PANTHER MAESTRO UniProtKB/TrEMBL
  MAESTRO-RELATED HEAT DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam Maestro_HEAT UniProtKB/TrEMBL
Superfamily-SCOP ARM repeat UniProtKB/TrEMBL
UniProt A0AAX6R5W3 ENTREZGENE, UniProtKB/TrEMBL