Lgals2 (galectin 2) - Rat Genome Database

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Gene: Lgals2 (galectin 2) Heterocephalus glaber
Analyze
Symbol: Lgals2
Name: galectin 2
RGD ID: 18910297
Description: ENCODES a protein that exhibits galactoside binding (ortholog); INVOLVED IN cell-cell adhesion (inferred); positive regulation of apoptotic process (inferred); positive regulation of inflammatory response (inferred); PARTICIPATES IN myocardial infarction pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); Coronary Disease (ortholog); Emery-Dreifuss muscular dystrophy (ortholog); FOUND IN galectin complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Galectin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,319,011 - 10,321,069 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,315,705 - 10,321,253 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Lgals2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,319,011 - 10,321,069 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,315,705 - 10,321,253 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LGALS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,570,248 - 37,580,087 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,570,248 - 37,582,616 (-)EnsemblGRCh38hg38GRCh38
GRCh372237,966,255 - 37,976,094 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,296,199 - 36,305,970 (-)NCBINCBI36Build 36hg18NCBI36
Build 342236,290,753 - 36,300,524NCBI
Celera2221,768,112 - 21,777,886 (-)NCBICelera
Cytogenetic Map22q13.1ENTREZGENE
HuRef2220,933,465 - 20,943,235 (-)NCBIHuRef
CHM1_12237,924,981 - 37,934,762 (-)NCBICHM1_1
T2T-CHM13v2.02238,031,510 - 38,041,349 (-)NCBIT2T-CHM13v2.0
Lgals2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,735,060 - 78,739,729 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,735,060 - 78,739,729 (-)EnsemblGRCm39 Ensembl
GRCm381578,850,860 - 78,855,529 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,850,860 - 78,855,529 (-)EnsemblGRCm38mm10GRCm38
MGSCv371578,681,290 - 78,685,959 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361579,578,396 - 79,579,182 (-)NCBIMGSCv36mm8
MGSCv361578,678,117 - 78,682,784 (-)NCBIMGSCv36mm8
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
Lgals2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,283,630 - 112,290,228 (-)NCBIGRCr8
mRatBN7.27110,403,171 - 110,410,046 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,403,173 - 110,404,802 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,153,320 - 112,159,807 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,376,850 - 114,383,337 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,345,224 - 114,351,701 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,071,122 - 120,077,612 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,071,124 - 120,077,612 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,062,255 - 120,069,133 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,811,332 - 116,817,822 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,845,563 - 116,852,052 (-)NCBI
Celera7106,737,582 - 106,744,072 (-)NCBICelera
Cytogenetic Map7q34NCBI
Lgals2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541323,988,193 - 23,989,703 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541323,988,193 - 24,001,868 (-)NCBIChiLan1.0ChiLan1.0
LGALS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,430,416 - 47,440,663 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,119,399 - 50,130,636 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,488,257 - 18,498,401 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,320,775 - 36,330,281 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2236,320,775 - 36,330,281 (-)Ensemblpanpan1.1panPan2
LGALS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,012,534 - 27,015,935 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,010,550 - 27,015,935 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,967,191 - 26,970,371 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,804,386 - 27,807,840 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,804,368 - 27,807,840 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,526,563 - 27,529,745 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,835,255 - 27,838,433 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,012,763 - 28,015,944 (+)NCBIUU_Cfam_GSD_1.0
Lgals2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,453,091 - 10,478,358 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364923,483,572 - 3,488,730 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364923,463,195 - 3,500,431 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LGALS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,237,745 - 10,250,162 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,237,772 - 10,244,555 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,795,590 - 7,802,388 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LGALS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,275,277 - 20,287,978 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045105,540,698 - 105,550,408 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000025867   ⟹   ENSHGLP00000025640
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475210,319,011 - 10,321,069 (+)Ensembl
RefSeq Acc Id: XM_004845653   ⟹   XP_004845710
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475210,315,705 - 10,321,253 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004845710 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB02177 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025640
  ENSHGLP00000050418
  ENSHGLP00100033775
RefSeq Acc Id: XP_004845710   ⟸   XM_004845653
- UniProtKB: G5AYX3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025640   ⟸   ENSHGLT00000025867


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018259 Ensembl, ENTREZGENE
  ENSHGLG00000032365 UniProtKB/TrEMBL
  ENSHGLG00100036332 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000025867 ENTREZGENE
  ENSHGLT00000077760 UniProtKB/TrEMBL
  ENSHGLT00100041974 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  Galectin-like UniProtKB/TrEMBL
  Galectin_CRD UniProtKB/TrEMBL
KEGG Report hgl:101721229 UniProtKB/TrEMBL
NCBI Gene Lgals2 ENTREZGENE
PANTHER GALECTIN-2 UniProtKB/TrEMBL
  PTHR11346 UniProtKB/TrEMBL
Pfam Gal-bind_lectin UniProtKB/TrEMBL
PROSITE GALECTIN UniProtKB/TrEMBL
SMART Gal-bind_lectin UniProtKB/TrEMBL
  GLECT UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/TrEMBL
UniProt G5AYX3 ENTREZGENE, UniProtKB/TrEMBL