LGALS2 (galectin 2) - Rat Genome Database

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Gene: LGALS2 (galectin 2) Canis lupus familiaris
Analyze
Symbol: LGALS2
Name: galectin 2
RGD ID: 12096803
Description: ENCODES a protein that exhibits galactoside binding (ortholog); INVOLVED IN cell-cell adhesion (inferred); positive regulation of apoptotic process (inferred); positive regulation of inflammatory response (inferred); PARTICIPATES IN myocardial infarction pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); Coronary Disease (ortholog); Emery-Dreifuss muscular dystrophy (ortholog); FOUND IN galectin complex (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: galectin-2; lectin, galactoside-binding, soluble, 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,012,534 - 27,015,935 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,010,550 - 27,015,935 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,967,191 - 26,970,371 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,804,386 - 27,807,840 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,804,368 - 27,807,840 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,526,563 - 27,529,745 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,835,255 - 27,838,433 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,012,763 - 28,015,944 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21127048   PMID:22301074  


Genomics

Comparative Map Data
LGALS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,012,534 - 27,015,935 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,010,550 - 27,015,935 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,967,191 - 26,970,371 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01027,804,386 - 27,807,840 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,804,368 - 27,807,840 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,526,563 - 27,529,745 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,835,255 - 27,838,433 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,012,763 - 28,015,944 (+)NCBIUU_Cfam_GSD_1.0
LGALS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,570,248 - 37,580,087 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,570,248 - 37,582,616 (-)EnsemblGRCh38hg38GRCh38
GRCh372237,966,255 - 37,976,094 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,296,199 - 36,305,970 (-)NCBINCBI36Build 36hg18NCBI36
Build 342236,290,753 - 36,300,524NCBI
Celera2221,768,112 - 21,777,886 (-)NCBICelera
Cytogenetic Map22q13.1ENTREZGENE
HuRef2220,933,465 - 20,943,235 (-)NCBIHuRef
CHM1_12237,924,981 - 37,934,762 (-)NCBICHM1_1
T2T-CHM13v2.02238,031,510 - 38,041,349 (-)NCBIT2T-CHM13v2.0
Lgals2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,735,060 - 78,739,729 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,735,060 - 78,739,729 (-)EnsemblGRCm39 Ensembl
GRCm381578,850,860 - 78,855,529 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,850,860 - 78,855,529 (-)EnsemblGRCm38mm10GRCm38
MGSCv371578,681,290 - 78,685,959 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361579,578,396 - 79,579,182 (-)NCBIMGSCv36mm8
MGSCv361578,678,117 - 78,682,784 (-)NCBIMGSCv36mm8
Cytogenetic Map15E1NCBI
cM Map1537.7NCBI
Lgals2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,283,630 - 112,290,228 (-)NCBIGRCr8
mRatBN7.27110,403,171 - 110,410,046 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,403,173 - 110,404,802 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,153,320 - 112,159,807 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,376,850 - 114,383,337 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,345,224 - 114,351,701 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,071,122 - 120,077,612 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,071,124 - 120,077,612 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,062,255 - 120,069,133 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47116,811,332 - 116,817,822 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17116,845,563 - 116,852,052 (-)NCBI
Celera7106,737,582 - 106,744,072 (-)NCBICelera
Cytogenetic Map7q34NCBI
Lgals2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541323,988,193 - 23,989,703 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541323,988,193 - 24,001,868 (-)NCBIChiLan1.0ChiLan1.0
LGALS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22347,430,416 - 47,440,663 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,119,399 - 50,130,636 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,488,257 - 18,498,401 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12236,320,775 - 36,330,281 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2236,320,775 - 36,330,281 (-)Ensemblpanpan1.1panPan2
Lgals2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,453,091 - 10,478,358 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364923,483,572 - 3,488,730 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364923,463,195 - 3,500,431 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LGALS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,237,745 - 10,250,162 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,237,772 - 10,244,555 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.257,795,590 - 7,802,388 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LGALS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,275,277 - 20,287,978 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045105,540,698 - 105,550,408 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lgals2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,319,011 - 10,321,069 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,315,705 - 10,321,253 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LGALS2
50 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 32 21 12 10 10

Sequence


Ensembl Acc Id: ENSCAFT00000002305   ⟹   ENSCAFP00000002128
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1027,013,925 - 27,015,935 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000068634   ⟹   ENSCAFP00000052081
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1027,010,550 - 27,015,935 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000087686   ⟹   ENSCAFP00000043631
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1027,012,464 - 27,015,910 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845010947   ⟹   ENSCAFP00845008541
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1027,804,368 - 27,807,815 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845010965   ⟹   ENSCAFP00845008558
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1027,805,830 - 27,807,840 (+)Ensembl
RefSeq Acc Id: NM_001284467   ⟹   NP_001271396
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11027,012,568 - 27,015,748 (+)NCBI
Dog10K_Boxer_Tasha1026,967,191 - 26,970,371 (+)NCBI
ROS_Cfam_1.01027,804,472 - 27,807,653 (+)NCBI
UMICH_Zoey_3.11027,526,563 - 27,529,745 (+)NCBI
UNSW_CanFamBas_1.01027,835,255 - 27,838,433 (+)NCBI
UU_Cfam_GSD_1.01028,012,763 - 28,015,944 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038678771   ⟹   XP_038534699
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01027,804,386 - 27,807,840 (+)NCBI
RefSeq Acc Id: NP_001271396   ⟸   NM_001284467
- UniProtKB: E5Q8W4 (UniProtKB/TrEMBL),   A0A8C0S327 (UniProtKB/TrEMBL),   A0A8I3MRH7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000043631   ⟸   ENSCAFT00000087686
Ensembl Acc Id: ENSCAFP00000052081   ⟸   ENSCAFT00000068634
Ensembl Acc Id: ENSCAFP00000002128   ⟸   ENSCAFT00000002305
RefSeq Acc Id: XP_038534699   ⟸   XM_038678771
- Peptide Label: isoform X1
- UniProtKB: A0A8C0QUX9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845008541   ⟸   ENSCAFT00845010947
Ensembl Acc Id: ENSCAFP00845008558   ⟸   ENSCAFT00845010965
Protein Domains
Galectin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001484 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010410 UniProtKB/TrEMBL
  ENSCAFG00040009390 UniProtKB/TrEMBL
  ENSCAFG00845006166 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000002305.5 UniProtKB/TrEMBL
  ENSCAFT00000068634.2 UniProtKB/TrEMBL
  ENSCAFT00000087686.2 UniProtKB/TrEMBL
  ENSCAFT00030019277.1 UniProtKB/TrEMBL
  ENSCAFT00030019359.1 UniProtKB/TrEMBL
  ENSCAFT00040017396.1 UniProtKB/TrEMBL
  ENSCAFT00040017471.1 UniProtKB/TrEMBL
  ENSCAFT00845010947 ENTREZGENE
  ENSCAFT00845010947.1 UniProtKB/TrEMBL
  ENSCAFT00845010965 ENTREZGENE
  ENSCAFT00845010965.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  Galectin-like UniProtKB/TrEMBL
  Galectin_CRD UniProtKB/TrEMBL
KEGG Report cfa:474514 UniProtKB/TrEMBL
NCBI Gene LGALS2 ENTREZGENE
PANTHER GALECTIN-2 UniProtKB/TrEMBL
  PTHR11346 UniProtKB/TrEMBL
Pfam Gal-bind_lectin UniProtKB/TrEMBL
PROSITE GALECTIN UniProtKB/TrEMBL
SMART Gal-bind_lectin UniProtKB/TrEMBL
  GLECT UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/TrEMBL
UniProt A0A8C0QUX9 ENTREZGENE
  A0A8C0S2U5_CANLF UniProtKB/TrEMBL
  A0A8C0S327 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MRH7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NDH9_CANLF UniProtKB/TrEMBL
  A0A8P0NU35_CANLF UniProtKB/TrEMBL
  E5Q8W4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:42647 ENTREZGENE