Ca2 (carbonic anhydrase 2) - Rat Genome Database

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Gene: Ca2 (carbonic anhydrase 2) Heterocephalus glaber
Analyze
Symbol: Ca2
Name: carbonic anhydrase 2
RGD ID: 18914119
Description: ENCODES a protein that exhibits arylesterase activity (ortholog); carbonate dehydratase activity (ortholog); INVOLVED IN angiotensin-activated signaling pathway (ortholog); carbon dioxide transport (ortholog); cellular response to fluid shear stress (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); Animal Disease Models (ortholog); autism spectrum disorder (ortholog); FOUND IN apical part of cell (ortholog); axon (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247446,167,606 - 6,183,538 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247446,168,030 - 6,183,407 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ca2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247446,167,606 - 6,183,538 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247446,168,030 - 6,183,407 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38885,464,007 - 85,481,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl885,463,968 - 85,481,493 (+)EnsemblGRCh38hg38GRCh38
GRCh37886,376,236 - 86,393,722 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36886,563,383 - 86,580,973 (+)NCBINCBI36Build 36hg18NCBI36
Build 34886,563,497 - 86,580,973NCBI
Celera882,381,194 - 82,398,781 (+)NCBICelera
Cytogenetic Map8q21.2NCBI
HuRef881,870,322 - 81,887,902 (+)NCBIHuRef
CHM1_1886,427,817 - 86,445,411 (+)NCBICHM1_1
T2T-CHM13v2.0885,902,727 - 85,920,191 (+)NCBIT2T-CHM13v2.0
Car2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39314,951,329 - 14,965,830 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl314,951,333 - 14,965,830 (+)EnsemblGRCm39 Ensembl
GRCm38314,886,269 - 14,900,770 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl314,886,273 - 14,900,770 (+)EnsemblGRCm38mm10GRCm38
MGSCv37314,886,426 - 14,900,770 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36314,863,469 - 14,877,513 (+)NCBIMGSCv36mm8
Celera314,899,001 - 14,912,886 (+)NCBICelera
Cytogenetic Map3A1NCBI
cM Map33.23NCBI
Car2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8288,462,883 - 88,478,012 (-)NCBIGRCr8
mRatBN7.2286,741,625 - 86,756,766 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl286,741,626 - 86,756,818 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx293,060,690 - 93,075,791 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0291,181,691 - 91,196,793 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0286,238,526 - 86,253,627 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0288,097,740 - 88,112,868 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl288,097,720 - 88,113,029 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02107,871,654 - 107,886,782 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4288,077,095 - 88,092,223 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1288,022,060 - 88,037,185 (-)NCBI
Celera282,339,410 - 82,354,537 (-)NCBICelera
Cytogenetic Map2q23NCBI
Ca2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554173,386,087 - 3,402,363 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554173,388,110 - 3,402,798 (+)NCBIChiLan1.0ChiLan1.0
CA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27101,201,646 - 101,219,667 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1876,834,337 - 76,852,343 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0881,991,037 - 82,009,010 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1883,601,163 - 83,618,327 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl883,597,440 - 83,632,580 (+)Ensemblpanpan1.1panPan2
CA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12931,959,225 - 31,975,309 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2931,935,172 - 31,980,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2932,190,440 - 32,197,007 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02932,108,070 - 32,124,176 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2932,107,905 - 32,129,372 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12932,159,433 - 32,175,512 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02932,180,668 - 32,196,793 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02932,567,770 - 32,583,867 (+)NCBIUU_Cfam_GSD_1.0
Ca2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530347,413,843 - 47,429,881 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936544362,591 - 380,223 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936544362,591 - 379,151 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl451,193,756 - 51,211,259 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1451,194,686 - 51,211,436 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2456,157,606 - 56,174,354 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1880,830,963 - 80,848,245 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl880,830,939 - 80,848,707 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603960,251,073 - 60,269,156 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000007856   ⟹   ENSHGLP00000007770
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247446,167,606 - 6,183,538 (-)Ensembl
RefSeq Acc Id: XM_004841979   ⟹   XP_004842036
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247446,168,030 - 6,183,407 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004842036 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000007770
  ENSHGLP00100023827
GenBank Protein JAN96734 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004842036   ⟸   XM_004841979
- UniProtKB: A0A0P6IYD3 (UniProtKB/TrEMBL),   G5ATW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000007770   ⟸   ENSHGLT00000007856


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005638 Ensembl, ENTREZGENE
  ENSHGLG00100017502 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000007856 ENTREZGENE
  ENSHGLT00100024070 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
KEGG Report hgl:101697802 UniProtKB/TrEMBL
NCBI Gene Ca2 ENTREZGENE
PANTHER CARBONIC ANHYDRASE 2 UniProtKB/TrEMBL
  PTHR18952 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A0P6IYD3 ENTREZGENE, UniProtKB/TrEMBL
  G5ATW7 ENTREZGENE, UniProtKB/TrEMBL