Cd24 (CD24 molecule) - Rat Genome Database

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Gene: Cd24 (CD24 molecule) Heterocephalus glaber
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Symbol: Cd24
Name: CD24 molecule
RGD ID: 18900317
Description: ENCODES a protein that exhibits carbohydrate binding (ortholog); Hsp70 protein binding (ortholog); Hsp90 protein binding (ortholog); INVOLVED IN apoptotic mitochondrial changes (ortholog); apoptotic nuclear changes (ortholog); apoptotic signaling pathway (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); multiple sclerosis (ortholog); pancreatic cancer (ortholog); FOUND IN cell surface (ortholog); ciliary membrane (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Signal transducer CD24
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478015,287,433 - 15,292,292 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478015,287,426 - 15,292,292 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic mitochondrial changes  (ISO)
apoptotic nuclear changes  (ISO)
apoptotic signaling pathway  (ISO)
B cell apoptotic process  (ISO)
B cell proliferation  (ISO)
B cell receptor transport into membrane raft  (ISS)
calcium-mediated signaling  (ISO)
CD4-positive, alpha-beta T cell proliferation  (ISO)
cell activation  (IEA,ISS)
cell adhesion  (IEA)
cell migration  (ISO)
cell surface receptor signaling pathway  (ISO)
chemokine receptor transport out of membrane raft  (ISO)
cholesterol homeostasis  (ISO)
glomerular parietal epithelial cell differentiation  (ISS)
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  (ISO)
homotypic cell-cell adhesion  (ISO)
immune response  (ISO)
integrin activation  (ISO)
leukocyte cell-cell adhesion  (ISO)
leukocyte migration involved in inflammatory response  (ISO)
negative regulation of B cell proliferation  (ISO)
negative regulation of erythrocyte aggregation  (ISO)
negative regulation of erythrocyte clearance  (ISO)
negative regulation of inflammatory response to wounding  (ISO)
negative regulation of interleukin-6 production  (ISO)
negative regulation of monocyte chemotactic protein-1 production  (ISO)
negative regulation of neuroblast proliferation  (ISO)
negative regulation of neurogenesis  (ISO)
negative regulation of neuron differentiation  (ISO)
negative regulation of T cell homeostatic proliferation  (ISO)
negative regulation of transforming growth factor beta3 production  (ISS)
negative regulation of tumor necrosis factor production  (ISO)
neuroblast proliferation  (ISO)
neuromuscular synaptic transmission  (ISO)
neuron projection development  (ISO)
peptidyl-tyrosine phosphorylation  (ISO)
podocyte differentiation  (ISS)
positive regulation of activated T cell proliferation  (ISS)
positive regulation of alpha-beta T cell proliferation  (ISO)
positive regulation of B cell apoptotic process  (ISO)
positive regulation of calcium-mediated signaling  (ISO)
positive regulation of CD4-positive, alpha-beta T cell proliferation  (ISO)
positive regulation of cell adhesion mediated by integrin  (ISO)
positive regulation of cell-cell adhesion  (ISO)
positive regulation of cell-cell adhesion mediated by integrin  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISS)
positive regulation of inflammatory response to antigenic stimulus  (ISO)
positive regulation of inflammatory response to wounding  (ISO)
positive regulation of integrin activation  (ISO)
positive regulation of MAP kinase activity  (ISS)
positive regulation of nephron tubule epithelial cell differentiation  (ISS)
positive regulation of neuron projection development  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of T cell homeostatic proliferation  (ISO)
positive regulation of T cell mediated immune response to tumor cell  (ISO)
pre-B cell differentiation  (ISO)
regulation of B cell differentiation  (ISO)
regulation of cell-cell adhesion  (IEA,ISO)
regulation of cell-cell adhesion mediated by integrin  (ISO)
regulation of cytokine-mediated signaling pathway  (ISO)
regulation of MAPK cascade  (ISS)
regulation of phosphorylation  (ISS)
respiratory burst  (ISO)
response to estrogen  (ISS)
response to hypoxia  (ISS)
response to molecule of bacterial origin  (ISO)
synaptic vesicle endocytosis  (ISO)
T cell costimulation  (ISS)
T cell homeostatic proliferation  (ISO)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cd24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478015,287,433 - 15,292,292 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478015,287,426 - 15,292,292 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CD24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386106,969,831 - 106,976,855 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6106,969,831 - 106,975,627 (-)EnsemblGRCh38hg38GRCh38
GRCh37619,611,914 - 19,614,093 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36621,152,527 - 21,154,705NCBINCBI36Build 36hg18NCBI36
Build 34Y19,540,683 - 19,542,776NCBI
CeleraY6,620,552 - 6,622,554 (+)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6104,864,115 - 104,868,879 (-)NCBIHuRef
T2T-CHM13v2.06108,145,896 - 108,152,920 (-)NCBIT2T-CHM13v2.0
Cd24a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391043,454,433 - 43,460,261 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1043,454,280 - 43,460,261 (+)EnsemblGRCm39 Ensembl
GRCm381043,579,169 - 43,584,265 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1043,578,284 - 43,584,265 (+)EnsemblGRCm38mm10GRCm38
MGSCv371043,298,975 - 43,304,071 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361043,267,584 - 43,272,680 (+)NCBIMGSCv36mm8
Celera1044,451,209 - 44,456,305 (+)NCBICelera
Cytogenetic Map10B2NCBI
cM Map1023.01NCBI
Cd24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82048,655,549 - 48,661,786 (+)NCBIGRCr8
mRatBN7.22047,074,353 - 47,079,662 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2047,073,512 - 47,079,662 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2048,789,167 - 48,794,459 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02048,439,001 - 48,444,293 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02049,123,655 - 49,128,973 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02048,335,540 - 48,340,847 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2048,335,540 - 48,340,846 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02049,989,320 - 49,994,627 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42047,502,354 - 47,507,663 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12047,531,055 - 47,536,352 (+)NCBI
Celera2052,908,730 - 52,914,027 (-)NCBICelera
RH 3.4 Map20495.52RGD
RH 3.4 Map20493.45RGD
Cytogenetic Map20q13NCBI
Cd24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541132,270,881 - 32,275,236 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541132,270,881 - 32,275,236 (-)NCBIChiLan1.0ChiLan1.0
LOC100982539
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25126,990,812 - 126,994,802 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16124,877,952 - 124,882,093 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06104,783,720 - 104,789,509 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11535,991,289 - 35,993,436 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6108,655,624 - 108,657,847 (-)NCBIpanpan1.1panPan2
CD24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11264,239,957 - 64,245,114 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1264,026,788 - 64,032,059 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01265,083,676 - 65,088,953 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11264,443,727 - 64,448,980 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01264,287,882 - 64,293,144 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01264,561,114 - 64,566,403 (-)NCBIUU_Cfam_GSD_1.0
LOC101968601
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629211,864,267 - 11,864,552 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493649116,706,745 - 16,707,010 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100519934
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1173,119,758 - 73,124,368 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2182,267,687 - 82,273,306 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CD24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11366,863,164 - 66,868,951 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604039,191,025 - 39,196,629 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000004361   ⟹   ENSHGLP00000004301
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462478015,287,433 - 15,292,292 (+)Ensembl
RefSeq Acc Id: XM_004855435   ⟹   XP_004855492
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478015,287,426 - 15,292,292 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004855492 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10550 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000004301
  ENSHGLP00100048978
RefSeq Acc Id: XP_004855492   ⟸   XM_004855435
- UniProtKB: G5BMN9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000004301   ⟸   ENSHGLT00000004361


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003147 Ensembl, ENTREZGENE
  ENSHGLG00100035088 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000004361 ENTREZGENE
  ENSHGLT00100081352 UniProtKB/TrEMBL
InterPro CD24 UniProtKB/TrEMBL
KEGG Report hgl:101704951 UniProtKB/TrEMBL
NCBI Gene Cd24 ENTREZGENE
PANTHER PTHR16676 UniProtKB/TrEMBL
  SIGNAL TRANSDUCER CD24 UniProtKB/TrEMBL
Pfam CD24 UniProtKB/TrEMBL
UniProt G5BMN9 ENTREZGENE, UniProtKB/TrEMBL