Agfg1 (ArfGAP with FG repeats 1) - Rat Genome Database

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Gene: Agfg1 (ArfGAP with FG repeats 1) Heterocephalus glaber
Analyze
Symbol: Agfg1
Name: ArfGAP with FG repeats 1
RGD ID: 18909304
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN acrosome assembly (ortholog); intermediate filament organization (ortholog); spermatid nucleus differentiation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); oligoasthenoteratozoospermia (ortholog); FOUND IN cell projection (ortholog); intracellular membrane-bounded organelle (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: arf-GAP domain and FG repeat-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248431,751,808 - 1,806,631 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248431,751,735 - 1,806,624 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Agfg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248431,751,808 - 1,806,631 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248431,751,735 - 1,806,624 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
AGFG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382227,472,156 - 227,561,217 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2227,472,152 - 227,561,217 (+)EnsemblGRCh38hg38GRCh38
GRCh372228,336,872 - 228,425,933 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362228,045,286 - 228,130,548 (+)NCBINCBI36Build 36hg18NCBI36
Build 342228,162,546 - 228,247,805NCBI
Celera2222,106,500 - 222,195,457 (+)NCBICelera
Cytogenetic Map2q36.3NCBI
HuRef2220,179,703 - 220,268,811 (+)NCBIHuRef
CHM1_12228,342,933 - 228,431,983 (+)NCBICHM1_1
T2T-CHM13v2.02227,954,843 - 228,043,867 (+)NCBIT2T-CHM13v2.0
Agfg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39182,816,738 - 82,878,722 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl182,817,204 - 82,878,903 (+)EnsemblGRCm39 Ensembl
GRCm38182,839,017 - 82,901,001 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl182,839,483 - 82,901,182 (+)EnsemblGRCm38mm10GRCm38
MGSCv37182,836,058 - 82,892,850 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36182,718,507 - 82,775,299 (+)NCBIMGSCv36mm8
Celera182,905,296 - 82,962,088 (+)NCBICelera
Cytogenetic Map1C5NCBI
cM Map142.55NCBI
Agfg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8991,572,962 - 91,630,688 (+)NCBIGRCr8
mRatBN7.2984,124,845 - 84,182,615 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl984,125,120 - 84,178,128 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx992,555,084 - 92,612,806 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0997,683,552 - 97,741,275 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0996,066,495 - 96,124,218 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0988,607,508 - 88,663,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl988,607,508 - 88,662,224 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0988,354,885 - 88,410,590 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4982,162,480 - 82,216,301 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera981,565,840 - 81,618,403 (+)NCBICelera
Cytogenetic Map9q34NCBI
Agfg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554537,069,806 - 7,109,703 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554537,066,509 - 7,127,878 (-)NCBIChiLan1.0ChiLan1.0
AGFG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213130,085,868 - 130,174,679 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B130,100,809 - 130,189,649 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B114,711,697 - 114,800,680 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B233,542,190 - 233,611,623 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B233,542,185 - 233,604,897 (+)Ensemblpanpan1.1panPan2
AGFG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12540,229,732 - 40,307,277 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2540,243,734 - 40,301,135 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2540,845,559 - 40,924,805 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02540,475,273 - 40,554,664 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2540,475,176 - 40,548,884 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12540,412,340 - 40,491,304 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02540,252,760 - 40,331,854 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02540,426,655 - 40,506,046 (+)NCBIUU_Cfam_GSD_1.0
Agfg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303182,421,491 - 182,483,054 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365258,463,475 - 8,504,188 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365258,463,475 - 8,504,201 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGFG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15128,898,705 - 128,975,510 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115128,898,806 - 128,980,782 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215142,743,993 - 142,774,355 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGFG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110113,500,174 - 113,589,243 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10113,500,391 - 113,582,474 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604085,867,490 - 85,955,907 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000004169   ⟹   ENSHGLP00000004111
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248431,751,808 - 1,806,631 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000004170   ⟹   ENSHGLP00000004112
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248431,751,808 - 1,806,631 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000004171   ⟹   ENSHGLP00000004113
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248431,751,808 - 1,804,272 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000004172   ⟹   ENSHGLP00000004114
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248431,751,808 - 1,804,272 (+)Ensembl
RefSeq Acc Id: XM_004867998   ⟹   XP_004868055
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,751,739 - 1,806,624 (+)NCBI
RefSeq Acc Id: XM_004868000   ⟹   XP_004868057
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,751,738 - 1,806,624 (+)NCBI
RefSeq Acc Id: XM_013066822   ⟹   XP_012922276
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,751,737 - 1,806,624 (+)NCBI
RefSeq Acc Id: XM_013066823   ⟹   XP_012922277
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,751,870 - 1,806,624 (+)NCBI
RefSeq Acc Id: XM_021247006   ⟹   XP_021102665
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,751,736 - 1,806,624 (+)NCBI
RefSeq Acc Id: XM_021247007   ⟹   XP_021102666
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,751,735 - 1,806,624 (+)NCBI
RefSeq Acc Id: XM_021247008   ⟹   XP_021102667
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,751,736 - 1,806,624 (+)NCBI
RefSeq Acc Id: XM_021247009   ⟹   XP_021102668
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,751,737 - 1,806,624 (+)NCBI
RefSeq Acc Id: XM_021247010   ⟹   XP_021102669
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,751,736 - 1,806,624 (+)NCBI
RefSeq Acc Id: XM_021247011   ⟹   XP_021102670
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,751,736 - 1,806,624 (+)NCBI
RefSeq Acc Id: XM_021247012   ⟹   XP_021102671
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,756,041 - 1,806,624 (+)NCBI
RefSeq Acc Id: XM_021247013   ⟹   XP_021102672
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248431,751,738 - 1,806,624 (+)NCBI
RefSeq Acc Id: XP_021102666   ⟸   XM_021247007
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JLE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102665   ⟸   XM_021247006
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JLE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102669   ⟸   XM_021247010
- Peptide Label: isoform X7
- UniProtKB: A0A0P6JLE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102667   ⟸   XM_021247008
- Peptide Label: isoform X4
- UniProtKB: A0A0P6JLE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102670   ⟸   XM_021247011
- Peptide Label: isoform X8
- UniProtKB: A0A0P6JLE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922276   ⟸   XM_013066822
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JLE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102668   ⟸   XM_021247009
- Peptide Label: isoform X5
- UniProtKB: A0A0P6JLE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102672   ⟸   XM_021247013
- Peptide Label: isoform X10
- UniProtKB: A0A0P6JLE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868057   ⟸   XM_004868000
- Peptide Label: isoform X12
- UniProtKB: A0A0P6JLE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868055   ⟸   XM_004867998
- Peptide Label: isoform X6
- UniProtKB: A0A0P6JLE9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922277   ⟸   XM_013066823
- Peptide Label: isoform X11
- UniProtKB: G5C9F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102671   ⟸   XM_021247012
- Peptide Label: isoform X9
- UniProtKB: G5C9F2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000004114   ⟸   ENSHGLT00000004172
Ensembl Acc Id: ENSHGLP00000004112   ⟸   ENSHGLT00000004170
Ensembl Acc Id: ENSHGLP00000004113   ⟸   ENSHGLT00000004171
Ensembl Acc Id: ENSHGLP00000004111   ⟸   ENSHGLT00000004169


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003021 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000004169 ENTREZGENE
  ENSHGLT00000004170 ENTREZGENE
  ENSHGLT00000004171 ENTREZGENE
  ENSHGLT00000004172 ENTREZGENE
Gene3D-CATH 1.10.220.150 UniProtKB/TrEMBL
  Longin domain UniProtKB/TrEMBL
InterPro Arf-GAP_FG-repeat_protein UniProtKB/TrEMBL
  ARFGAP/RecO UniProtKB/TrEMBL
  ArfGAP_dom UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/TrEMBL
NCBI Gene Agfg1 ENTREZGENE
PANTHER ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  DRONGO, ISOFORM F UniProtKB/TrEMBL
Pfam ArfGap UniProtKB/TrEMBL
PRINTS REVINTRACTNG UniProtKB/TrEMBL
PROSITE ARFGAP UniProtKB/TrEMBL
SMART ArfGap UniProtKB/TrEMBL
Superfamily-SCOP SSF57863 UniProtKB/TrEMBL
UniProt A0A0P6JLE9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6Q589_HETGA UniProtKB/TrEMBL
  A0AAX6Q591_HETGA UniProtKB/TrEMBL
  A0AAX6QKD7_HETGA UniProtKB/TrEMBL
  A0AAX6QNP2_HETGA UniProtKB/TrEMBL
  A0AAX6RY21_HETGA UniProtKB/TrEMBL
  A0AAX6RZJ7_HETGA UniProtKB/TrEMBL
  A0AAX6S1R3_HETGA UniProtKB/TrEMBL
  A0AAX6S1W9_HETGA UniProtKB/TrEMBL
  A0AAX6S2C7_HETGA UniProtKB/TrEMBL
  A0AAX6S2V7_HETGA UniProtKB/TrEMBL
  A0AAX6S3T8_HETGA UniProtKB/TrEMBL
  A0AAX6S4Y6_HETGA UniProtKB/TrEMBL
  G5C9F2 ENTREZGENE, UniProtKB/TrEMBL