Clp1 (cleavage factor polyribonucleotide kinase subunit 1) - Rat Genome Database

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Gene: Clp1 (cleavage factor polyribonucleotide kinase subunit 1) Heterocephalus glaber
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Symbol: Clp1
Name: cleavage factor polyribonucleotide kinase subunit 1 (Ensembl:cleavage and polyadenylation factor I subunit 1)
RGD ID: 18907020
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity (inferred); ATP-dependent polynucleotide 5'-hydroxyl-kinase activity (inferred); INVOLVED IN cerebellar cortex development (ortholog); global gene silencing by mRNA cleavage (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; tRNA maturation pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cleavage and polyadenylation factor I subunit 1; Polyribonucleotide 5'-hydroxyl-kinase Clp1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248643,063,555 - 3,067,051 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248643,063,555 - 3,067,045 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Clp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248643,063,555 - 3,067,051 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248643,063,555 - 3,067,045 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CLP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381157,657,762 - 57,661,865 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1157,648,188 - 57,661,865 (+)EnsemblGRCh38hg38GRCh38
GRCh371157,425,234 - 57,429,337 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,181,206 - 57,185,913 (+)NCBINCBI36Build 36hg18NCBI36
Celera1154,781,701 - 54,785,822 (+)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1153,774,137 - 53,778,258 (+)NCBIHuRef
CHM1_11157,291,424 - 57,295,545 (+)NCBICHM1_1
T2T-CHM13v2.01157,607,935 - 57,612,038 (+)NCBIT2T-CHM13v2.0
Clp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,553,466 - 84,557,631 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl284,552,448 - 84,557,694 (-)EnsemblGRCm39 Ensembl
GRCm38284,723,122 - 84,727,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl284,722,104 - 84,727,350 (-)EnsemblGRCm38mm10GRCm38
MGSCv37284,563,279 - 84,567,425 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36284,523,961 - 84,528,107 (-)NCBIMGSCv36mm8
Celera286,318,290 - 86,322,440 (-)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.45NCBI
Clp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8390,213,461 - 90,217,165 (-)NCBIGRCr8
mRatBN7.2369,806,774 - 69,818,633 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl369,806,778 - 69,810,421 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx373,188,581 - 73,192,284 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0381,787,243 - 81,790,946 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0379,546,170 - 79,549,873 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0372,125,269 - 72,137,122 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,125,273 - 72,128,973 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0378,645,908 - 78,657,782 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4367,934,068 - 67,937,772 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1367,830,439 - 67,834,144 (-)NCBI
Celera369,162,457 - 69,166,161 (-)NCBICelera
Cytogenetic Map3q24NCBI
Clp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555112,588,825 - 2,593,192 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555112,588,825 - 2,592,108 (+)NCBIChiLan1.0ChiLan1.0
CLP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2958,794,718 - 58,818,214 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11159,826,329 - 59,838,193 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01152,898,181 - 52,902,656 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11156,368,732 - 56,373,129 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1156,368,433 - 56,373,129 (+)Ensemblpanpan1.1panPan2
CLP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,528,700 - 38,531,899 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1838,528,621 - 38,530,846 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1838,075,104 - 38,078,316 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01839,210,508 - 39,213,726 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1839,210,508 - 39,213,629 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11838,793,608 - 38,796,826 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01838,366,628 - 38,369,840 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01838,997,368 - 39,000,586 (-)NCBIUU_Cfam_GSD_1.0
Clp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494714,756,010 - 14,759,418 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365814,869,686 - 4,873,217 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365814,870,126 - 4,873,158 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl213,282,164 - 13,285,162 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1213,282,157 - 13,285,208 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2212,915,349 - 12,918,466 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CLP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1115,568,984 - 15,573,849 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl115,568,976 - 15,573,082 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038112,920,089 - 112,924,752 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000014013   ⟹   ENSHGLP00000013872
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248643,063,555 - 3,067,051 (-)Ensembl
RefSeq Acc Id: XM_004869771   ⟹   XP_004869828
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248643,063,555 - 3,067,045 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004869828 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10158 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000013872
GenBank Protein JAO03011 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004869828   ⟸   XM_004869771
- UniProtKB: G5BLJ7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000013872   ⟸   ENSHGLT00000014013


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009914 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000014013 ENTREZGENE
Gene3D-CATH 2.40.30.330 UniProtKB/TrEMBL
  2.60.120.1030 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro Clp1 UniProtKB/TrEMBL
  Clp1/Grc3 UniProtKB/TrEMBL
  Clp1_C UniProtKB/TrEMBL
  Clp1_C_sf UniProtKB/TrEMBL
  Clp1_N UniProtKB/TrEMBL
  Clp1_N_sf UniProtKB/TrEMBL
  CLP1_P UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report hgl:101723956 UniProtKB/TrEMBL
NCBI Gene Clp1 ENTREZGENE
PANTHER POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1 UniProtKB/TrEMBL
  PTHR12755 UniProtKB/TrEMBL
Pfam Clp1 UniProtKB/TrEMBL
  CLP1_N UniProtKB/TrEMBL
  CLP1_P UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt G5BLJ7 ENTREZGENE, UniProtKB/TrEMBL