Hif1a (hypoxia inducible factor 1 subunit alpha) - Rat Genome Database

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Gene: Hif1a (hypoxia inducible factor 1 subunit alpha) Heterocephalus glaber
Analyze
Symbol: Hif1a
Name: hypoxia inducible factor 1 subunit alpha
RGD ID: 18910437
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); protein-containing complex binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN acute-phase response (ortholog); angiogenesis (ortholog); apoptotic process (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute-Phase Reaction (ortholog); Alcoholic Liver Diseases (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypoxia inducible factor 1 alpha subunit; hypoxia-inducible factor 1-alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473439,411,824 - 39,471,705 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473439,414,458 - 39,471,705 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
Acute-Phase Reaction  (ISO)
Alcoholic Liver Diseases  (ISO)
Alzheimer's disease  (ISO)
Anaplasia  (ISO)
Arterial Thrombosis  (ISO)
Asphyxia  (ISO)
asthma  (ISO)
atrial fibrillation  (ISO)
bladder neck obstruction  (ISO)
Brain Hypoxia-Ischemia  (ISO)
brain infarction  (ISO)
brain ischemia  (ISO)
Breast Neoplasms  (ISO)
bronchopulmonary dysplasia  (ISO)
Burns  (ISO)
carcinoma  (ISO)
Cardiomegaly  (ISO)
cerebral infarction  (ISO)
cholangiocarcinoma  (ISO)
cholesteatoma of middle ear  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Cerebral Hypoperfusion  (ISO)
Chronic Intermittent Hypoxia  (ISO)
chronic obstructive pulmonary disease  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
congenital heart disease  (ISO)
congestive heart failure  (ISO)
decubitus ulcer  (ISO)
Diabetes Complications  (ISO)
Diabetic Foot  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
Disease Progression  (ISO)
Ductal Carcinoma  (ISO)
ductal carcinoma in situ  (ISO)
esophagus squamous cell carcinoma  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Neuritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Mammary Neoplasms  (ISO)
Experimental Neoplasms  (ISO)
Experimental Radiation Injuries  (ISO)
Femur Head Necrosis  (ISO)
glioblastoma  (ISO)
glycogen storage disease V  (ISO)
glycogen storage disease VII  (ISO)
Hearing Loss, Noise-Induced  (ISO)
hemangioblastoma  (ISO)
hepatic encephalopathy  (ISO)
hepatocellular carcinoma  (ISO)
Hot Flashes  (ISO)
Hyperalgesia  (ISO)
Hyperplasia  (ISO)
hypertension  (ISO)
idiopathic pulmonary fibrosis  (ISO)
Infarction  (ISO)
interstitial cystitis  (ISO)
Intervertebral Disc Disease  (ISO)
Intervertebral Disc Displacement  (ISO)
invasive ductal carcinoma  (ISO)
kidney failure  (ISO)
Kidney Reperfusion Injury  (ISO)
limb ischemia  (ISO)
liver cirrhosis  (ISO)
lung disease  (ISO)
lung non-small cell carcinoma  (ISO)
macular retinal edema  (ISO)
Maffucci syndrome  (ISO)
malignant astrocytoma  (ISO)
Memory Disorders  (ISO)
Micronuclei, Chromosome-Defective  (ISO)
middle cerebral artery infarction  (ISO)
morbid obesity  (ISO)
mycosis fungoides  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplastic Cell Transformation  (ISO)
nephroblastoma  (ISO)
obesity  (ISO)
olfactory neuroblastoma  (ISO)
Ollier disease  (ISO)
osteoarthritis  (ISO)
ovarian cancer  (ISO)
Oxygen-Induced Retinopathy  (ISO)
pancreatic cancer  (ISO)
Phyllodes Tumor  (ISO)
polycystic kidney disease  (ISO)
Postmenopausal Osteoporosis  (ISO)
pre-eclampsia  (ISO)
primary biliary cholangitis  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
proteinuria  (ISO)
psoriasis  (ISO)
pulmonary hypertension  (ISO)
Radiation Injuries  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
retinal ischemia  (ISO)
Retinal Neovascularization  (ISO)
rheumatoid arthritis  (ISO)
sclerosing cholangitis  (ISO)
skin melanoma  (ISO)
Skin Neoplasms  (ISO)
Spinal Cord Injuries  (ISO)
Subarachnoid Hemorrhage  (ISO)
Temporomandibular Joint Disorders  (ISO)
Testis Reperfusion Injury  (ISO)
Thyroid Neoplasms  (ISO)
transient cerebral ischemia  (ISO)
type 2 diabetes mellitus  (ISO)
Ulcer  (ISO)
urinary bladder cancer  (ISO)
Urologic Neoplasms  (ISO)
varicocele  (ISO)
Venous Thrombosis  (ISO)
Ventricular Remodeling  (ISO)
Werner syndrome  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute-phase response  (ISO)
angiogenesis  (IEA,ISO)
apoptotic process  (IEA,ISO)
axonal transport of mitochondrion  (IEA)
B-1 B cell homeostasis  (IEA,ISO)
blood vessel development  (IEA,ISO)
blood vessel morphogenesis  (IEA,ISO)
bone mineralization  (IEA,ISO)
camera-type eye morphogenesis  (IEA,ISO)
cardiac ventricle morphogenesis  (IEA,ISO)
cartilage development  (IEA,ISO)
cell differentiation  (IEA,ISO)
cellular response to anoxia  (ISO)
cellular response to carbon monoxide  (ISO)
cellular response to cobalt ion  (ISO)
cellular response to cyanide  (ISO)
cellular response to electrical stimulus  (ISO)
cellular response to estrogen stimulus  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to hypoxia  (IEA,ISO)
cellular response to insulin stimulus  (ISO)
cellular response to interleukin-1  (IEA,ISO)
cellular response to light stimulus  (ISO)
cellular response to lipid  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to nitrite  (ISO)
cellular response to oxidative stress  (IEA)
cellular response to phorbol 13-acetate 12-myristate  (ISO)
cellular response to toxic substance  (ISO)
cellular response to virus  (IEA)
cellular response to wortmannin  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cerebral cortex development  (IEA,ISO)
chondrocyte differentiation  (IEA,ISO)
collagen metabolic process  (IEA)
connective tissue replacement involved in inflammatory response wound healing  (IEA)
digestive tract morphogenesis  (IEA,ISO)
dopaminergic neuron differentiation  (IEA,ISO)
elastin metabolic process  (IEA)
embryonic hemopoiesis  (IEA,ISO)
embryonic placenta development  (IEA,ISO)
epithelial cell differentiation involved in mammary gland alveolus development  (IEA,ISO)
epithelial to mesenchymal transition  (IEA)
glandular epithelial cell differentiation  (IEA,ISO)
glandular epithelial cell maturation  (IEA,ISO)
glucose homeostasis  (IEA,ISO)
heart development  (ISO)
heart looping  (IEA,ISO)
hemoglobin biosynthetic process  (IEA,ISO)
hypoxia-inducible factor-1alpha signaling pathway  (IEA,ISO)
insulin secretion involved in cellular response to glucose stimulus  (IEA,ISO)
intestinal epithelial cell maturation  (IEA,ISO)
intracellular glucose homeostasis  (IEA)
intracellular iron ion homeostasis  (IEA,ISO)
intracellular oxygen homeostasis  (IEA,ISO)
iris morphogenesis  (IEA,ISO)
iron import into the mitochondrion  (ISO)
lactate metabolic process  (IEA,ISO)
lactation  (IEA,ISO)
lung development  (ISO)
maternal process involved in female pregnancy  (ISO)
mesenchymal cell apoptotic process  (IEA,ISO)
muscle cell cellular homeostasis  (IEA,ISO)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of bone mineralization  (IEA,ISO)
negative regulation of gene expression  (IEA)
negative regulation of growth  (IEA,ISO)
negative regulation of mesenchymal cell apoptotic process  (IEA,ISO)
negative regulation of miRNA transcription  (IEA)
negative regulation of neuron apoptotic process  (IEA,ISO)
negative regulation of ossification  (IEA)
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway  (IEA)
negative regulation of reactive oxygen species biosynthetic process  (ISO)
negative regulation of thymocyte apoptotic process  (IEA,ISO)
negative regulation of TOR signaling  (IEA,ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of vasoconstriction  (ISO)
neural crest cell migration  (IEA,ISO)
neural fold elevation formation  (IEA,ISO)
neuroblast proliferation  (IEA,ISO)
neuron apoptotic process  (IEA,ISO)
outflow tract morphogenesis  (IEA,ISO)
positive regulation of angiogenesis  (IEA)
positive regulation of apoptotic process  (ISO)
positive regulation of blood vessel endothelial cell migration  (IEA)
positive regulation of cell population proliferation  (ISO)
positive regulation of cell size  (ISO)
positive regulation of chemokine-mediated signaling pathway  (IEA,ISO)
positive regulation of cytokine production involved in inflammatory response  (IEA)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of endothelial cell migration  (ISO)
positive regulation of epithelial cell migration  (IEA)
positive regulation of erythrocyte differentiation  (IEA,ISO)
positive regulation of gene expression  (IEA,ISO)
positive regulation of gluconeogenesis  (ISO)
positive regulation of glycolytic process  (IEA,ISO)
positive regulation of hormone biosynthetic process  (IEA)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (IEA,ISO)
positive regulation of macroautophagy  (IEA,ISO)
positive regulation of miRNA transcription  (IEA)
positive regulation of neuroblast proliferation  (IEA,ISO)
positive regulation of signaling receptor activity  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of sprouting angiogenesis  (ISO)
positive regulation of stress granule assembly  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of vascular endothelial growth factor production  (IEA,ISO)
positive regulation of vascular endothelial growth factor receptor signaling pathway  (IEA,ISO)
positive regulation of vascular wound healing  (ISO)
regulation of catalytic activity  (ISO)
regulation of cell population proliferation  (IEA,ISO)
regulation of cellular response to hypoxia  (ISO)
regulation of DNA-templated transcription  (IEA,ISO)
regulation of gene expression  (IEA)
regulation of glycolytic process  (IEA,ISO)
regulation of protein neddylation  (IEA)
regulation of thymocyte apoptotic process  (IEA,ISO)
regulation of transcription by RNA polymerase II  (IEA,ISO)
regulation of transforming growth factor beta2 production  (IEA)
response to activity  (ISO)
response to alkaloid  (ISO)
response to anesthetic  (ISO)
response to auditory stimulus  (ISO)
response to cobalt ion  (ISO)
response to estradiol  (ISO)
response to estrogen  (ISO)
response to fungicide  (ISO)
response to glucocorticoid  (ISO)
response to glucose  (ISO)
response to hypoxia  (IEA,ISO)
response to iron ion  (IEA)
response to mechanical stimulus  (ISO)
response to muscle activity  (IEA,ISO)
response to purine-containing compound  (ISO)
response to reactive oxygen species  (IEA)
response to salt stress  (ISO)
response to X-ray  (ISO)
response to xenobiotic stimulus  (ISO)
retina vasculature development in camera-type eye  (IEA,ISO)
signal transduction  (IEA)
tissue remodeling  (ISO)
TOR signaling  (IEA,ISO)
vascular endothelial growth factor production  (IEA)
vasculature development  (IEA,ISO)
visual learning  (IEA,ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22103690   PMID:22301074   PMID:26763976   PMID:30032202  


Genomics

Comparative Map Data
Hif1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473439,411,824 - 39,471,705 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473439,414,458 - 39,471,705 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HIF1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381461,695,513 - 61,748,258 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1461,695,513 - 61,748,259 (+)EnsemblGRCh38hg38GRCh38
GRCh371462,162,231 - 62,214,976 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361461,231,992 - 61,284,729 (+)NCBINCBI36Build 36hg18NCBI36
Build 341461,231,991 - 61,284,729NCBI
Celera1442,212,391 - 42,265,247 (+)NCBICelera
Cytogenetic Map14q23.2NCBI
HuRef1442,326,005 - 42,378,869 (+)NCBIHuRef
CHM1_11462,101,569 - 62,154,420 (+)NCBICHM1_1
T2T-CHM13v2.01455,902,080 - 55,954,826 (+)NCBIT2T-CHM13v2.0
Hif1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391273,948,186 - 73,994,304 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1273,948,149 - 73,994,304 (+)EnsemblGRCm39 Ensembl
GRCm381273,901,324 - 73,947,554 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1273,901,375 - 73,947,530 (+)EnsemblGRCm38mm10GRCm38
MGSCv371275,008,854 - 75,048,517 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361274,826,868 - 74,865,729 (+)NCBIMGSCv36mm8
Celera1275,021,612 - 75,061,060 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1231.99NCBI
Hif1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8698,357,788 - 98,405,068 (+)NCBIGRCr8
mRatBN7.2692,624,059 - 92,669,262 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl692,624,390 - 92,669,261 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx693,016,163 - 93,061,234 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0693,315,666 - 93,360,736 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0692,743,543 - 92,788,613 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0696,810,868 - 96,856,303 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl696,810,907 - 96,856,052 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06106,242,409 - 106,287,957 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4696,419,024 - 96,463,891 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1696,422,479 - 96,467,347 (+)NCBI
Celera691,083,300 - 91,128,125 (+)NCBICelera
Cytogenetic Map6q24NCBI
Hif1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554668,000,044 - 8,022,497 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554668,000,311 - 8,022,497 (-)NCBIChiLan1.0ChiLan1.0
HIF1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21562,825,050 - 62,878,472 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11462,041,761 - 62,094,986 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01442,295,691 - 42,348,478 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11460,552,374 - 60,604,885 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1460,552,374 - 60,604,885 (+)Ensemblpanpan1.1panPan2
HIF1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1836,614,045 - 36,656,692 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl836,614,045 - 36,656,692 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha836,366,891 - 36,409,562 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0836,847,226 - 36,889,848 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl836,847,066 - 36,889,846 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1836,456,745 - 36,499,380 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0836,534,215 - 36,576,862 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0836,896,640 - 36,939,279 (+)NCBIUU_Cfam_GSD_1.0
Hif1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864068,375,541 - 68,420,766 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364955,770,669 - 5,816,157 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364955,770,988 - 5,816,157 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIF1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1190,625,244 - 190,674,845 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11190,625,436 - 190,673,926 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21212,130,958 - 212,179,888 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HIF1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12438,873,830 - 38,927,657 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2438,873,861 - 38,928,288 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605327,124,225 - 27,177,215 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000022647   ⟹   ENSHGLP00000022435
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473439,411,824 - 39,471,705 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000022648   ⟹   ENSHGLP00000022436
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473439,415,901 - 39,441,346 (-)Ensembl
RefSeq Acc Id: NM_001310267   ⟹   NP_001297196
RefSeq Status: VALIDATED
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473439,414,707 - 39,471,705 (-)NCBI
RefSeq Acc Id: XM_004837433   ⟹   XP_004837490
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473439,414,458 - 39,471,447 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001297196 (Get FASTA)   NCBI Sequence Viewer  
  XP_004837490 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ADN26631 (Get FASTA)   NCBI Sequence Viewer  
  AIZ09006 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000022435
  ENSHGLP00100004427
RefSeq Acc Id: XP_004837490   ⟸   XM_004837433
- Peptide Label: isoform X1
- UniProtKB: A0AAX6NV34 (UniProtKB/TrEMBL),   G5C5I4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001297196   ⟸   NM_001310267
- UniProtKB: A0A0A7HSI3 (UniProtKB/TrEMBL),   G5C5I4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000022436   ⟸   ENSHGLT00000022648
Ensembl Acc Id: ENSHGLP00000022435   ⟸   ENSHGLT00000022647


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016000 Ensembl, ENTREZGENE
  ENSHGLG00100003349 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000022647 ENTREZGENE
  ENSHGLT00100004496 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HIF-1_alpha UniProtKB/TrEMBL
  HIF-1_TAD_C UniProtKB/TrEMBL
  HIF_alpha_subunit UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  PAC UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold UniProtKB/TrEMBL
  PAS_fold_3 UniProtKB/TrEMBL
KEGG Report hgl:101715845 UniProtKB/TrEMBL
NCBI Gene Hif1a ENTREZGENE
PANTHER HYPOXIA-INDUCIBLE FACTOR 1 ALPHA UniProtKB/TrEMBL
  HYPOXIA-INDUCIBLE FACTOR 1-ALPHA UniProtKB/TrEMBL
Pfam HIF-1 UniProtKB/TrEMBL
  HIF-1a_CTAD UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS_3 UniProtKB/TrEMBL
PRINTS HYPOXIAIF1A UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
  PAC UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
  SSF55785 UniProtKB/TrEMBL
UniProt A0A0A7HSI3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6NV34 ENTREZGENE, UniProtKB/TrEMBL
  E2J833_HETGA UniProtKB/TrEMBL
  G5C5I4 ENTREZGENE, UniProtKB/TrEMBL