Cnp (2',3'-cyclic nucleotide 3' phosphodiesterase) - Rat Genome Database

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Gene: Cnp (2',3'-cyclic nucleotide 3' phosphodiesterase) Heterocephalus glaber
Analyze
Symbol: Cnp
Name: 2',3'-cyclic nucleotide 3' phosphodiesterase
RGD ID: 18936014
Description: ENCODES a protein that exhibits 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity (ortholog); cyclic nucleotide binding (ortholog); INVOLVED IN adult locomotory behavior (ortholog); axonogenesis (ortholog); forebrain development (ortholog); ASSOCIATED WITH alcoholic liver cirrhosis (ortholog); Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ortholog); FOUND IN cell projection (ortholog); extracellular space (ortholog); microtubule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 2',3'-cyclic-nucleotide 3'-phosphodiesterase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,855,992 - 1,861,053 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,856,455 - 1,861,142 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cnp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247951,855,992 - 1,861,053 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247951,856,455 - 1,861,142 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CNP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,966,795 - 41,977,740 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1741,966,763 - 41,977,740 (+)EnsemblGRCh38hg38GRCh38
GRCh371740,118,813 - 40,129,758 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361737,372,285 - 37,383,280 (+)NCBINCBI36Build 36hg18NCBI36
Build 341737,372,284 - 37,383,280NCBI
Celera1736,773,458 - 36,784,455 (+)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,884,123 - 35,895,118 (+)NCBIHuRef
CHM1_11740,354,523 - 40,365,518 (+)NCBICHM1_1
T2T-CHM13v2.01742,823,292 - 42,834,237 (+)NCBIT2T-CHM13v2.0
Cnp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911100,465,765 - 100,472,565 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11100,465,730 - 100,482,555 (+)EnsemblGRCm39 Ensembl
GRCm3811100,574,909 - 100,591,875 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,574,904 - 100,591,729 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711100,436,253 - 100,443,053 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,391,065 - 100,397,815 (+)NCBIMGSCv36mm8
Celera11111,195,104 - 111,201,904 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.47NCBI
Cnp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,011,504 - 86,018,063 (+)NCBIGRCr8
mRatBN7.21085,511,164 - 85,517,723 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1085,511,160 - 85,517,720 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1090,548,000 - 90,554,559 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,026,520 - 90,033,080 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01085,419,429 - 85,425,988 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01088,490,798 - 88,497,357 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,490,798 - 88,497,356 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,284,045 - 88,290,604 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,519,421 - 89,525,978 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11089,533,790 - 89,540,348 (+)NCBI
Celera1084,227,529 - 84,234,088 (+)NCBICelera
RH 3.4 Map10859.8RGD
Cytogenetic Map10q31NCBI
Cnp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545116,114,454 - 16,118,622 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545116,115,137 - 16,119,261 (+)NCBIChiLan1.0ChiLan1.0
CNP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21923,008,706 - 23,017,228 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,898,864 - 24,907,379 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01715,338,085 - 15,349,089 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11715,560,056 - 15,569,108 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1715,560,056 - 15,568,916 (-)Ensemblpanpan1.1panPan2
CNP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,888,350 - 20,896,139 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,886,574 - 20,896,079 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,349,053 - 20,356,835 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0921,606,902 - 21,614,689 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl921,594,095 - 21,614,688 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1920,392,407 - 20,400,181 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,659,216 - 20,666,990 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,762,355 - 20,770,140 (-)NCBIUU_Cfam_GSD_1.0
Cnp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560220,233,405 - 20,240,592 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649016,834,540 - 16,841,810 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649016,834,570 - 16,841,734 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,758,083 - 20,765,553 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,758,081 - 20,765,655 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21221,048,293 - 21,055,830 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CNP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11664,288,583 - 64,296,940 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1664,289,828 - 64,296,922 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607735,106,165 - 35,114,853 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000023562   ⟹   ENSHGLP00000023345
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247951,855,992 - 1,861,053 (-)Ensembl
RefSeq Acc Id: XM_004859381   ⟹   XP_004859438
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247951,856,455 - 1,861,142 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004859438 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023345
  ENSHGLP00100016611
GenBank Protein JAN97832 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004859438   ⟸   XM_004859381
- UniProtKB: A0A0P6J5G8 (UniProtKB/TrEMBL),   G5B0L2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000023345   ⟸   ENSHGLT00000023562


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016638 Ensembl, ENTREZGENE
  ENSHGLG00100012266 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000023562 ENTREZGENE
  ENSHGLT00100016790 UniProtKB/TrEMBL
Gene3D-CATH 2',3'-cyclic nucleotide 3'-phosphodiesterase superfamily UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro CNPase UniProtKB/TrEMBL
  CNPase_cat UniProtKB/TrEMBL
  Cyclic_Pdiesterase UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report hgl:101703085 UniProtKB/TrEMBL
NCBI Gene Cnp ENTREZGENE
PANTHER 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE UniProtKB/TrEMBL
  PTHR10156 UniProtKB/TrEMBL
Pfam AAA_33 UniProtKB/TrEMBL
  CNPase UniProtKB/TrEMBL
PIRSF CNPase UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF55144 UniProtKB/TrEMBL
UniProt A0A0P6J5G8 ENTREZGENE, UniProtKB/TrEMBL
  G5B0L2 ENTREZGENE, UniProtKB/TrEMBL