Cd53 (CD53 molecule) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Cd53 (CD53 molecule) Heterocephalus glaber
Analyze
Symbol: Cd53
Name: CD53 molecule
RGD ID: 18923737
Description: ENCODES a protein that exhibits protein-membrane adaptor activity (ortholog); INVOLVED IN cell-cell adhesion (ortholog); receptor clustering (ortholog); regulation of myoblast differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Experimental Liver Cirrhosis (ortholog); Gastro-Enteropancreatic Neuroendocrine Tumor (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Leukocyte surface antigen CD53
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247726,630,123 - 6,661,599 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247726,630,152 - 6,660,871 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cd53
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247726,630,123 - 6,661,599 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247726,630,152 - 6,660,871 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CD53
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381110,871,210 - 110,899,922 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1110,871,188 - 110,899,922 (+)EnsemblGRCh38hg38GRCh38
GRCh371111,413,832 - 111,442,544 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361111,215,344 - 111,244,081 (+)NCBINCBI36Build 36hg18NCBI36
Build 341111,127,814 - 111,234,716NCBI
Celera1109,660,823 - 109,689,572 (+)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1109,285,008 - 109,313,782 (+)NCBIHuRef
CHM1_11111,528,958 - 111,557,705 (+)NCBICHM1_1
T2T-CHM13v2.01110,885,966 - 110,914,720 (+)NCBIT2T-CHM13v2.0
Cd53
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393106,666,177 - 106,697,465 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3106,667,237 - 106,697,465 (-)EnsemblGRCm39 Ensembl
GRCm383106,758,861 - 106,790,149 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3106,759,921 - 106,790,149 (-)EnsemblGRCm38mm10GRCm38
MGSCv373106,561,779 - 106,593,067 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363106,887,989 - 106,918,107 (-)NCBIMGSCv36mm8
Celera3109,088,034 - 109,119,379 (-)NCBICelera
Cytogenetic Map3F2.3NCBI
cM Map346.53NCBI
Cd53
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82197,040,369 - 197,087,925 (-)NCBIGRCr8
mRatBN7.22194,352,139 - 194,399,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2194,352,139 - 194,399,657 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2201,985,357 - 202,031,562 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02199,865,663 - 199,913,115 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02194,682,627 - 194,730,079 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02209,489,279 - 209,537,098 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2209,489,279 - 209,537,087 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02228,956,378 - 229,004,197 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42202,186,125 - 202,234,570 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12202,148,878 - 202,197,324 (-)NCBI
Celera2187,021,863 - 187,068,114 (-)NCBICelera
RH 3.4 Map21352.8RGD
Cytogenetic Map2q34NCBI
Cd53
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543514,388,726 - 14,413,249 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543514,388,925 - 14,410,543 (+)NCBIChiLan1.0ChiLan1.0
CD53
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21116,142,917 - 116,172,063 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11115,291,592 - 115,320,348 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01113,517,715 - 113,546,466 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11126,799,910 - 126,828,671 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1126,799,910 - 126,826,714 (-)Ensemblpanpan1.1panPan2
CD53
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1641,070,132 - 41,089,329 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl641,070,788 - 41,089,221 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha643,847,669 - 43,866,859 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0641,401,987 - 41,421,177 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl641,401,991 - 41,421,159 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1641,122,453 - 41,141,639 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0641,092,762 - 41,111,952 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0641,528,153 - 41,547,338 (-)NCBIUU_Cfam_GSD_1.0
Cd53
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505817,828,648 - 17,850,910 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367042,262,945 - 2,285,631 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367042,263,248 - 2,285,625 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD53
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4109,306,555 - 109,335,802 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14109,306,552 - 109,335,876 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24119,674,096 - 119,703,422 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD53
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12022,653,361 - 22,687,172 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2022,652,819 - 22,685,287 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603835,778,039 - 35,806,921 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000010102   ⟹   ENSHGLP00000009991
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247726,630,123 - 6,661,599 (+)Ensembl
RefSeq Acc Id: XM_004853695   ⟹   XP_004853752
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247726,630,152 - 6,660,871 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004853752 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB07244 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000009991
  ENSHGLP00100053525
GenBank Protein JAO01392 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004853752   ⟸   XM_004853695
- UniProtKB: G5BD83 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000009991   ⟸   ENSHGLT00000010102


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007172 Ensembl, ENTREZGENE
  ENSHGLG00100015154 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000010102 ENTREZGENE
  ENSHGLT00100052132 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1450.10 UniProtKB/TrEMBL
InterPro Tetraspanin/Peripherin UniProtKB/TrEMBL
  Tetraspanin_animals UniProtKB/TrEMBL
  Tetraspanin_CS UniProtKB/TrEMBL
  Tetraspanin_EC2_sf UniProtKB/TrEMBL
KEGG Report hgl:101719625 UniProtKB/TrEMBL
NCBI Gene Cd53 ENTREZGENE
PANTHER LEUKOCYTE SURFACE ANTIGEN CD53 UniProtKB/TrEMBL
  PTHR19282 UniProtKB/TrEMBL
Pfam Tetraspanin UniProtKB/TrEMBL
PIRSF Tetraspanin UniProtKB/TrEMBL
PRINTS TMFOUR UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  TM4_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48652 UniProtKB/TrEMBL
UniProt G5BD83 ENTREZGENE, UniProtKB/TrEMBL