CD53 (CD53 molecule) - Rat Genome Database

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Gene: CD53 (CD53 molecule) Canis lupus familiaris
Analyze
Symbol: CD53
Name: CD53 molecule
RGD ID: 12204707
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein-membrane adaptor activity (ortholog); INVOLVED IN cell-cell adhesion (ortholog); receptor clustering (ortholog); regulation of myoblast differentiation (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Gastro-Enteropancreatic Neuroendocrine Tumor (ortholog); FOUND IN cell surface (ortholog); immunological synapse (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leukocyte surface antigen CD53
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1641,070,132 - 41,089,329 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl641,070,788 - 41,089,221 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha643,847,669 - 43,866,859 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0641,401,987 - 41,421,177 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl641,401,991 - 41,421,159 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1641,122,453 - 41,141,639 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0641,092,762 - 41,111,952 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0641,528,153 - 41,547,338 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CD53
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1641,070,132 - 41,089,329 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl641,070,788 - 41,089,221 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha643,847,669 - 43,866,859 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0641,401,987 - 41,421,177 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl641,401,991 - 41,421,159 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1641,122,453 - 41,141,639 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0641,092,762 - 41,111,952 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0641,528,153 - 41,547,338 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CD53
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381110,871,210 - 110,899,922 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1110,871,170 - 110,899,936 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh371111,413,832 - 111,442,544 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361111,215,344 - 111,244,081 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341111,127,814 - 111,234,716NCBI
Celera1109,660,823 - 109,689,572 (+)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1109,285,008 - 109,313,782 (+)NCBIHuRef
CHM1_11111,528,958 - 111,557,705 (+)NCBICHM1_1
T2T-CHM13v2.01110,885,966 - 110,914,720 (+)NCBIT2T-CHM13v2.0
Cd53
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393106,666,177 - 106,697,465 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3106,666,177 - 106,697,530 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm383106,758,861 - 106,790,149 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3106,759,921 - 106,790,149 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv373106,561,779 - 106,593,067 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv363106,887,989 - 106,918,107 (-)NCBIMGSCv36mm8
Celera3109,088,034 - 109,119,379 (-)NCBICelera
Cytogenetic Map3F2.3NCBI
cM Map346.53NCBI
Cd53
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82197,040,369 - 197,087,925 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2197,040,369 - 197,218,593 (-)EnsemblGRCr8
mRatBN7.22194,352,139 - 194,399,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2194,352,139 - 194,399,657 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2201,985,357 - 202,031,562 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02199,865,663 - 199,913,115 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02194,682,627 - 194,730,079 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd2196,665,336 - 196,717,899 (-)NCBI
Lyon_Normotensive2196,904,513 - 196,957,076 (-)NCBI
Lyon_Hypertensive2196,511,320 - 196,563,914 (-)NCBI
F344_StmMcwi2196,623,040 - 196,675,636 (-)NCBI
Rnor_6.02209,489,279 - 209,537,098 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2209,489,279 - 209,537,087 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.02228,956,378 - 229,004,197 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42202,186,125 - 202,234,570 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2187,021,863 - 187,068,114 (-)NCBICelera
RGSC_v3.12202,148,878 - 202,197,324 (-)NCBI
RH 3.4 Map21352.8RGD
Cytogenetic Map2q34NCBI
Cd53
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543514,388,726 - 14,413,249 (+)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495543514,388,925 - 14,410,543 (+)NCBIChiLan1.0ChiLan1.0
CD53
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21116,142,917 - 116,172,063 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11115,291,592 - 115,320,348 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01113,517,715 - 113,546,466 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11126,799,910 - 126,828,671 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1126,799,910 - 126,826,714 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
Cd53
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap111103,974,709 - 103,997,100 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_02440505817,828,648 - 17,850,910 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367042,262,945 - 2,285,631 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367042,263,248 - 2,285,625 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD53
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4109,306,555 - 109,335,802 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.14109,306,552 - 109,335,876 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24119,674,096 - 119,703,422 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD53
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap12025,662,425 - 25,691,302 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366603835,778,039 - 35,806,921 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.12022,653,361 - 22,687,172 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2022,652,819 - 22,685,287 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Cd53
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247726,630,152 - 6,660,871 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046247726,630,123 - 6,661,599 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl1916,263,040 - 16,497,345 (-)Ensembl
Cd53
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1351,318,031 - 51,461,652 (+)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in CD53
96 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000031438   ⟹   ENSCAFP00000029263
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl641,070,788 - 41,089,221 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000086679   ⟹   ENSCAFP00000048986
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl641,070,788 - 41,077,216 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845003133   ⟹   ENSCAFP00845002496
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl641,401,991 - 41,421,159 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845003136   ⟹   ENSCAFP00845002498
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl641,401,991 - 41,409,064 (-)Ensembl
RefSeq Acc Id: XM_003639132   ⟹   XP_003639180
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1641,070,132 - 41,089,329 (-)NCBI
Dog10K_Boxer_Tasha643,847,669 - 43,866,859 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038479755   ⟹   XP_038335683
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1641,122,453 - 41,141,639 (-)NCBI
RefSeq Acc Id: XM_038541026   ⟹   XP_038396954
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0641,528,153 - 41,547,338 (-)NCBI
RefSeq Acc Id: XM_038605153   ⟹   XP_038461081
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0641,092,762 - 41,111,952 (-)NCBI
RefSeq Acc Id: XM_038669827   ⟹   XP_038525755
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0641,401,987 - 41,421,177 (-)NCBI
RefSeq Acc Id: XP_003639180   ⟸   XM_003639132
- UniProtKB: A0A8I3MMD4 (UniProtKB/TrEMBL),   A0A8C0K906 (UniProtKB/TrEMBL),   A0A8I3RQ75 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000029263   ⟸   ENSCAFT00000031438
Ensembl Acc Id: ENSCAFP00000048986   ⟸   ENSCAFT00000086679
RefSeq Acc Id: XP_038335683   ⟸   XM_038479755
RefSeq Acc Id: XP_038461081   ⟸   XM_038605153
RefSeq Acc Id: XP_038525755   ⟸   XM_038669827
- UniProtKB: A0A8I3MMD4 (UniProtKB/TrEMBL),   A0A8C0K906 (UniProtKB/TrEMBL),   A0A8I3RQ75 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038396954   ⟸   XM_038541026
- UniProtKB: A0A8C0K906 (UniProtKB/TrEMBL),   A0A8I3MMD4 (UniProtKB/TrEMBL),   A0A8I3RQ75 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845002498   ⟸   ENSCAFT00845003136
Ensembl Acc Id: ENSCAFP00845002496   ⟸   ENSCAFT00845003133

Promoters
RGD ID:13683779
Promoter ID:EPDNEW_C1846
Type:multiple initiation site
Name:CD53_1
Description:CD53 molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1641,089,271 - 41,089,331EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019772 Ensembl
  ENSCAFG00845001785 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845003133 ENTREZGENE
  ENSCAFT00845003133.1 UniProtKB/TrEMBL
  ENSCAFT00845003136.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1450.10 UniProtKB/TrEMBL
InterPro Tetraspanin/Peripherin UniProtKB/TrEMBL
  Tetraspanin_animals UniProtKB/TrEMBL
  Tetraspanin_CS UniProtKB/TrEMBL
  Tetraspanin_EC2_sf UniProtKB/TrEMBL
KEGG Report cfa:100855953 UniProtKB/TrEMBL
NCBI Gene CD53 ENTREZGENE
PANTHER LEUKOCYTE SURFACE ANTIGEN CD53 UniProtKB/TrEMBL
  PTHR19282 UniProtKB/TrEMBL
Pfam Tetraspanin UniProtKB/TrEMBL
PIRSF Tetraspanin UniProtKB/TrEMBL
PRINTS TMFOUR UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  TM4_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48652 UniProtKB/TrEMBL
UniProt A0A8C0K906 ENTREZGENE
  A0A8I3MMD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RQ75 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:38964 ENTREZGENE