Ptpn1 (protein tyrosine phosphatase non-receptor type 1) - Rat Genome Database

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Gene: Ptpn1 (protein tyrosine phosphatase non-receptor type 1) Heterocephalus glaber
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Symbol: Ptpn1
Name: protein tyrosine phosphatase non-receptor type 1
RGD ID: 18917874
Description: ENCODES a protein that exhibits insulin receptor binding (ortholog); phosphatase activity (ortholog); protein phosphatase 2A binding (ortholog); INVOLVED IN cellular response to angiotensin (ortholog); cellular response to fibroblast growth factor stimulus (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; insulin signaling pathway; insulin-like growth factor signaling pathway; ASSOCIATED WITH B-cell lymphoma (ortholog); Calcification of Aortic Valve (ortholog); Carotid Artery Injuries (ortholog); FOUND IN glutamatergic synapse (ortholog); mitochondrial crista (ortholog); mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tyrosine-protein phosphatase non-receptor type 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247905,073,476 - 5,135,181 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247905,070,537 - 5,135,243 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 16 of 16 rows

  
Object Symbol
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Evidence
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Reference
Notes
Source
Original Reference(s)
Ptpn1Naked Mole-RatCalcification of Aortic Valve  ISORGD:13436399068941protein:increased expression:aortic valve (human)RGDPMID:35958694|REF_RGD_ID:401976381
Ptpn1Naked Mole-RatCarotid Artery Injuries  ISORGD:619659068941protein:increased expression:carotid artery (rat)RGDPMID:15271661|REF_RGD_ID:401965432
Ptpn1Naked Mole-RatCarotid Artery Injuries  ISORGD:619659068941mRNA:increased expression:carotid artery (rat)RGDPMID:10807732|REF_RGD_ID:9590128
Ptpn1Naked Mole-RatCarotid Artery Injuries exacerbatesISORGD:619659068941 RGDPMID:16373608|REF_RGD_ID:401965416
Ptpn1Naked Mole-Ratcoronary artery disease  ISORGD:13436399068941DNA:SNP:exon 8:g.981C>T (human)RGDPMID:21676396|REF_RGD_ID:401965429
Ptpn1Naked Mole-Ratdiabetes mellitus  ISORGD:13436399068941protein:increased expression:skin of forearm (human)RGDPMID:22688339|REF_RGD_ID:8547813
Ptpn1Naked Mole-Ratessential hypertension susceptibilityISORGD:13436399068941DNA:SNPs::g.54281T>A, 15/37C>A (human)RGDPMID:20101100|REF_RGD_ID:401959376
Ptpn1Naked Mole-RatExperimental Diabetes Mellitus  ISORGD:622589068941protein:increased activity:retina (mouse)RGDPMID:19029027|REF_RGD_ID:401965415
Ptpn1Naked Mole-Rathyperinsulinism  ISORGD:619659068941associated with Carotid Artery Injuries;mRNA, protein:altered expression, altered activity:carotid artery (rat)RGDPMID:19011046|REF_RGD_ID:401965418
Ptpn1Naked Mole-Rathypertension treatmentISORGD:619659068941associated with obesityRGDPMID:29562733|REF_RGD_ID:401976390
Ptpn1Naked Mole-Rathypertension treatmentISORGD:619659068941 RGDPMID:29859467|REF_RGD_ID:401976391
Ptpn1Naked Mole-Ratlimb ischemia  ISORGD:622589068941protein:increased expression, increased activity:hindlimb muscle (mouse)RGDPMID:18451337|REF_RGD_ID:401965417
Ptpn1Naked Mole-Ratproliferative diabetic retinopathy  ISORGD:13436399068941protein:increased expression:vitreous humor (human)RGDPMID:33627831|REF_RGD_ID:401976389
Ptpn1Naked Mole-RatStroke  ISORGD:622589068941protein:increased expression:cerebral cortex (mouse)RGDPMID:32788467|REF_RGD_ID:401976392
Ptpn1Naked Mole-Rattype 2 diabetes mellitus no_associationISORGD:13436399068941DNA:missense mutation:CDS:p.P387L (human)RGDPMID:15715684|REF_RGD_ID:401965404
Ptpn1Naked Mole-RatWounds and Injuries treatmentISORGD:622589068941associated with Experimental Diabetes MellitusRGDPMID:25395617|REF_RGD_ID:401965402
1 to 16 of 16 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptpn1Naked Mole-RatInsulin Resistance  ISORGD:13436398554872ClinVar Annotator: match by term: Insulin resistance, susceptibility toClinVarPMID:11833006
Ptpn1Naked Mole-Rattype 2 diabetes mellitus  ISORGD:13436398554872ClinVar Annotator: match by term: PTPN1-related conditionClinVarPMID:25741868|PMID:28492532
1 to 9 of 9 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptpn1Naked Mole-RatB-cell lymphoma  ISORGD:13436399068941CTD Direct Evidence: marker/mechanismCTDPMID:24531327
Ptpn1Naked Mole-RatExperimental Liver Cirrhosis  ISORGD:13436399068941CTD Direct Evidence: marker/mechanismCTDPMID:26739621
Ptpn1Naked Mole-RatHodgkin's lymphoma  ISORGD:13436399068941CTD Direct Evidence: marker/mechanismCTDPMID:24531327
Ptpn1Naked Mole-Rathyperinsulinism  ISORGD:13436399068941CTD Direct Evidence: therapeuticCTDPMID:28899902
Ptpn1Naked Mole-Rathypertension  ISORGD:13436399068941CTD Direct Evidence: therapeuticCTDPMID:28899902
Ptpn1Naked Mole-RatInflammation  ISORGD:13436399068941CTD Direct Evidence: therapeuticCTDPMID:28899902
Ptpn1Naked Mole-RatMediastinal Neoplasms  ISORGD:13436399068941CTD Direct Evidence: marker/mechanismCTDPMID:24531327
Ptpn1Naked Mole-Ratobesity  ISORGD:13436399068941CTD Direct Evidence: marker/mechanismCTDPMID:10744717|PMID:20075852
Ptpn1Naked Mole-RatRett syndrome  ISORGD:13436399068941CTD Direct Evidence: marker/mechanismCTDPMID:26214522
1 to 9 of 9 rows
Object Symbol
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Original Reference(s)
Ptpn1Naked Mole-Rattype 2 diabetes mellitus susceptibilityISORGD:13436397240710 OMIM 


Biological Process
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Object Symbol
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Source
Original Reference(s)
Ptpn1Naked Mole-Ratactin cytoskeleton organization involved_inIEAUniProtKB:P18031|ensembl:ENSP00000360683150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratcellular response to angiotensin  ISORGD:619659068941 RGDPMID:31502193|REF_RGD_ID:401976382
Ptpn1Naked Mole-Ratcellular response to fibroblast growth factor stimulus  ISORGD:619659068941 RGDPMID:15271661|REF_RGD_ID:401965432
Ptpn1Naked Mole-Ratcellular response to hypoxia  ISORGD:619659068941 RGDPMID:18278556|REF_RGD_ID:401965430
Ptpn1Naked Mole-Ratcellular response to insulin stimulus  ISORGD:619659068941 RGDPMID:18456732|REF_RGD_ID:401976379
Ptpn1Naked Mole-Ratcellular response to nerve growth factor stimulus  ISORGD:619659068941 RGDPMID:18796006|REF_RGD_ID:401965471
Ptpn1Naked Mole-Ratcellular response to nitric oxide  ISORGD:619659068941 RGDPMID:12117721|REF_RGD_ID:401965428
Ptpn1Naked Mole-Ratcellular response to platelet-derived growth factor stimulus  ISORGD:619659068941 RGDPMID:15271661|PMID:18456732|REF_RGD_ID:401965432|REF_RGD_ID:401976379
Ptpn1Naked Mole-Ratdephosphorylation  ISORGD:619659068941 RGDPMID:10409197|REF_RGD_ID:401965431
Ptpn1Naked Mole-Ratendoplasmic reticulum unfolded protein response involved_inIEAUniProtKB:P18031|ensembl:ENSP00000360683150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratinsulin receptor recycling involved_inIEAUniProtKB:P35821|ensembl:ENSMUSP00000029053150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratinsulin receptor signaling pathway acts_upstream_of_or_withinIEAUniProtKB:P35821|ensembl:ENSMUSP00000029053150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-RatIRE1-mediated unfolded protein response involved_inIEAUniProtKB:P35821|ensembl:ENSMUSP00000029053150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratnegative regulation of cell population proliferation  ISORGD:619659068941 RGDPMID:16373608|REF_RGD_ID:401965416
Ptpn1Naked Mole-Ratnegative regulation of cell-substrate adhesion  ISORGD:619659068941 RGDPMID:10484424|REF_RGD_ID:401965470
Ptpn1Naked Mole-Ratnegative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway involved_inIEAUniProtKB:P35821|ensembl:ENSMUSP00000029053150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratnegative regulation of ERK1 and ERK2 cascade involved_inIEAUniProtKB:P35821|ensembl:ENSMUSP00000029053150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratnegative regulation of ERK1 and ERK2 cascade involved_inIEAPANTHER:PTN000439581|PANTHER:PTN000439582150520179 TreeGrafterGO_REF:0000118
Ptpn1Naked Mole-Ratnegative regulation of MAP kinase activity involved_inISORGD:13436399068941 PMID:22045810CACAOPMID:22045810
Ptpn1Naked Mole-Ratnegative regulation of neuron projection development  ISORGD:619659068941 RGDPMID:18796006|REF_RGD_ID:401965471
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Cellular Component
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Object Symbol
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Original Reference(s)
Ptpn1Naked Mole-Ratcytoplasm located_inIEAPANTHER:PTN000439581|PANTHER:PTN000439582150520179 TreeGrafterGO_REF:0000118
Ptpn1Naked Mole-Ratcytoplasm located_inIEAUniProtKB:P35821|ensembl:ENSMUSP00000029053150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratcytoplasmic side of endoplasmic reticulum membrane located_inIEAUniProtKB:P18031|ensembl:ENSP00000360683150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratcytosol located_inIEAUniProtKB:A8K3M3|UniProtKB:P18031|ensembl:ENSP00000360683150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratearly endosome located_inIEAUniProtKB:P18031|UniProtKB:P35821|ensembl:ENSMUSP00000029053|ensembl:ENSP00000360683150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratearly endosome located_inIEAPANTHER:PTN000439581|PANTHER:PTN000439582150520179 TreeGrafterGO_REF:0000118
Ptpn1Naked Mole-Ratendomembrane system located_inIEAUniProtKB-SubCell:SL-0147150520179 UniProtGO_REF:0000044
Ptpn1Naked Mole-Ratendoplasmic reticulum located_inIEAUniProtKB:A8K3M3|UniProtKB:P18031|ensembl:ENSP00000360683150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratendoplasmic reticulum located_inIEAPANTHER:PTN000439581|PANTHER:PTN000439582150520179 TreeGrafterGO_REF:0000118
Ptpn1Naked Mole-Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-0256150520179 UniProtGO_REF:0000043
Ptpn1Naked Mole-Ratendoplasmic reticulum located_inIEAUniProtKB-SubCell:SL-0095150520179 UniProtGO_REF:0000044
Ptpn1Naked Mole-Ratendosome lumen is_active_inIEAUniProtKB:P35821|ensembl:ENSMUSP00000029053150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratglutamatergic synapse is_active_inISORGD:619659068941PMID:22844492SynGOPMID:22844492|REF_RGD_ID:405650356
Ptpn1Naked Mole-Ratmembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
Ptpn1Naked Mole-Ratmitochondrial crista part_ofISORGD:619659068941PMID:18583343CACAOPMID:18583343|REF_RGD_ID:15023487
Ptpn1Naked Mole-Ratmitochondrial matrix part_ofISORGD:619659068941PMID:18583343CACAOPMID:18583343|REF_RGD_ID:15023487
Ptpn1Naked Mole-Ratplasma membrane located_inIEAUniProtKB:P18031|ensembl:ENSP00000360683150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratpostsynapse is_active_inISORGD:619659068941PMID:22844492SynGOPMID:22844492|REF_RGD_ID:405650356
Ptpn1Naked Mole-Ratprotein-containing complex part_ofIEAUniProtKB:P18031|ensembl:ENSP00000360683150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratsorting endosome located_inIEAUniProtKB:P35821|ensembl:ENSMUSP00000029053150520179 EnsemblGO_REF:0000107
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Molecular Function
1 to 20 of 66 rows

  
Object Symbol
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Evidence
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Source
Original Reference(s)
Ptpn1Naked Mole-Ratenzyme binding enablesIEAUniProtKB:P18031|ensembl:ENSP00000360683150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Ratephrin receptor binding enablesIEAUniProtKB:P18031|ensembl:ENSP00000360683150520179 EnsemblGO_REF:0000107
Ptpn1Naked Mole-Rathydrolase activity enablesIEAUniProtKB-KW:KW-0378150520179 UniProtGO_REF:0000043
Ptpn1Naked Mole-Ratinsulin receptor binding  ISORGD:619659068941 RGDPMID:12850498|PMID:7711057|REF_RGD_ID:1580595|REF_RGD_ID:2293185
Ptpn1Naked Mole-Ratnon-membrane spanning protein tyrosine phosphatase activity enablesIEAPANTHER:PTN000439581|PANTHER:PTN000439582150520179 TreeGrafterGO_REF:0000118
Ptpn1Naked Mole-Ratphosphatase activity  ISORGD:619659068941 RGDPMID:10409197|REF_RGD_ID:401965431
Ptpn1Naked Mole-Ratphosphoprotein phosphatase activity enablesIEAUniProtKB-KW:KW-0904150520179 UniProtGO_REF:0000043
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:P11274-19068941 PMID:9566916IntActPMID:9566916
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:P005339068941PMID:7693694IntActPMID:7693694|REF_RGD_ID:8554805
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:O43561|UniProtKB:P129319068941 PMID:12857726IntActPMID:12857726
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:P35570|UniProtKB:P629939068941 PMID:10660596IntActPMID:10660596
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:P08581|UniProtKB:P129319068941 PMID:16537444IntActPMID:16537444
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:P57054|UniProtKB:Q13520|UniProtKB:Q8N661|UniProtKB:Q96HV5|UniProtKB:Q9GZR5|UniProtKB:Q9NPL89068941 PMID:32296183IntActPMID:32296183
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:P00533|UniProtKB:P629939068941 PMID:31980649IntActPMID:31980649
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:P07384|UniProtKB:P569459068941 PMID:9407132IntActPMID:9407132
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:P62994|UniProtKB:Q61140|UniProtKB:Q63768|UniProtKB:Q9WUD99068941 PMID:12023880IntActPMID:12023880
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:P569459068941 PMID:10889023IntActPMID:10889023
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:Q9WUD99068941 PMID:31585087IntActPMID:31585087
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:P06213|UniProtKB:P631669068941 PMID:17159996IntActPMID:17159996
Ptpn1Naked Mole-Ratprotein binding enablesISOUniProtKB:P085819068941 PMID:18579758, PMID:22789536IntActPMID:18579758|PMID:22789536
1 to 20 of 66 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptpn1Naked Mole-Ratinsulin signaling pathway   ISORGD:619659068941 RGDPMID:12850498|PMID:7711057|REF_RGD_ID:1580595|REF_RGD_ID:2293185
Ptpn1Naked Mole-Ratinsulin signaling pathway   ISORGD:13436399068941 RGDPMID:17347799|REF_RGD_ID:1625124
Ptpn1Naked Mole-RatJak-Stat signaling pathway   ISORGD:13436399068941 RGDPMID:16426581|REF_RGD_ID:2290530
Ptpn1Naked Mole-Ratleptin system pathway   ISORGD:13436399068941 RGDPMID:15821101|REF_RGD_ID:2289366

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ptpn1Naked Mole-Ratepidermal growth factor/neuregulin signaling pathway   ISORGD:13436399068941 PIDPID:200101
Ptpn1Naked Mole-Ratinsulin signaling pathway   ISORGD:13436399068941 PIDPID:200014
Ptpn1Naked Mole-Ratinsulin-like growth factor signaling pathway  ISORGD:13436399068941 PIDPID:200100
Ptpn1Naked Mole-RatN-cadherin signaling pathway  ISORGD:13436399068941 PIDPID:200209
Ptpn1Naked Mole-Ratplatelet-derived growth factor signaling pathway  ISORGD:13436399068941 PIDPID:200149
PMID:22301074  



Ptpn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247905,073,476 - 5,135,181 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247905,070,537 - 5,135,243 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PTPN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382050,510,383 - 50,585,241 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2050,510,321 - 50,585,241 (+)EnsemblGRCh38hg38GRCh38
GRCh372049,126,920 - 49,201,778 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362048,560,298 - 48,634,495 (+)NCBINCBI36Build 36hg18NCBI36
Build 342048,560,297 - 48,634,491NCBI
Celera2045,831,156 - 45,905,376 (+)NCBICelera
Cytogenetic Map20q13.13NCBI
HuRef2045,875,585 - 45,950,061 (+)NCBIHuRef
CHM1_12049,031,996 - 49,106,433 (+)NCBICHM1_1
T2T-CHM13v2.02052,280,015 - 52,354,899 (+)NCBIT2T-CHM13v2.0
Ptpn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392167,772,670 - 167,821,305 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2167,773,977 - 167,821,305 (+)EnsemblGRCm39 Ensembl
GRCm382167,930,750 - 167,979,385 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2167,932,057 - 167,979,385 (+)EnsemblGRCm38mm10GRCm38
MGSCv372167,757,827 - 167,804,885 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362167,623,579 - 167,668,124 (+)NCBIMGSCv36mm8
Celera2173,874,374 - 173,921,508 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map287.99NCBI
Ptpn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83177,056,588 - 177,106,424 (+)NCBIGRCr8
mRatBN7.23156,638,811 - 156,687,503 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3156,638,769 - 156,687,504 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3160,433,645 - 160,479,965 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03168,932,730 - 168,979,050 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03166,674,429 - 166,720,749 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03164,665,462 - 164,711,936 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3164,665,532 - 164,711,848 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03170,816,897 - 170,866,071 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43159,070,473 - 159,116,792 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13158,976,466 - 159,025,198 (+)NCBI
Celera3155,215,176 - 155,261,496 (+)NCBICelera
Cytogenetic Map3q42NCBI
Ptpn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554457,754,319 - 7,819,275 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554457,754,313 - 7,819,229 (-)NCBIChiLan1.0ChiLan1.0
PTPN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22156,258,978 - 56,333,733 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12056,252,091 - 56,326,654 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02046,854,918 - 46,929,509 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12047,983,098 - 48,057,421 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2047,983,098 - 48,057,421 (+)Ensemblpanpan1.1panPan2
PTPN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12436,936,469 - 37,010,929 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2436,936,298 - 37,003,720 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2436,179,442 - 36,246,435 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02437,642,503 - 37,713,189 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2437,642,561 - 37,712,561 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12436,882,533 - 36,949,558 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02437,016,127 - 37,083,208 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02437,560,457 - 37,627,492 (+)NCBIUU_Cfam_GSD_1.0
Ptpn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640188,603,904 - 188,630,208 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365144,068,238 - 4,084,009 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365144,065,455 - 4,083,847 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1752,017,130 - 52,086,736 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11752,017,100 - 52,086,747 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21758,450,256 - 58,474,772 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1213,385,681 - 13,459,180 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl213,387,727 - 13,459,105 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605061,816,170 - 61,890,307 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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Ensembl Acc Id: ENSHGLT00000007041   ⟹   ENSHGLP00000006957
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247905,073,476 - 5,135,181 (-)Ensembl
RefSeq Acc Id: XM_013077154   ⟹   XP_012932608
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247905,070,540 - 5,135,243 (-)NCBI
RefSeq Acc Id: XM_013077155   ⟹   XP_012932609
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247905,070,540 - 5,135,243 (-)NCBI
RefSeq Acc Id: XM_021238924   ⟹   XP_021094583
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247905,070,537 - 5,135,243 (-)NCBI
Protein RefSeqs XP_012932608 (Get FASTA)   NCBI Sequence Viewer  
  XP_012932609 (Get FASTA)   NCBI Sequence Viewer  
  XP_021094583 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006957
RefSeq Acc Id: XP_021094583   ⟸   XM_021238924
- Peptide Label: isoform X3
- UniProtKB: A0AAX6RE42 (UniProtKB/TrEMBL),   G5AZ02 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012932609   ⟸   XM_013077155
- Peptide Label: isoform X2
- UniProtKB: A0AAX6R314 (UniProtKB/TrEMBL),   G5AZ02 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012932608   ⟸   XM_013077154
- Peptide Label: isoform X1
- UniProtKB: A0AAX6R286 (UniProtKB/TrEMBL),   G5AZ02 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000006957   ⟸   ENSHGLT00000007041



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Database
Acc Id
Source(s)
Ensembl Genes ENSHGLG00000005082 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000007041 ENTREZGENE
Gene3D-CATH Protein tyrosine phosphatase superfamily UniProtKB/TrEMBL
InterPro NR_tyrosine_phosphatase UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTP_cat UniProtKB/TrEMBL
  Ptpn1/Ptpn2 UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_dom UniProtKB/TrEMBL
NCBI Gene Ptpn1 ENTREZGENE
PANTHER TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 UniProtKB/TrEMBL
  TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F UniProtKB/TrEMBL
Pfam Y_phosphatase UniProtKB/TrEMBL
PIRSF Tyr-Ptase_nr1 UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP (Phosphotyrosine protein) phosphatases II UniProtKB/TrEMBL
UniProt A0AAX6R286 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R314 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RE42 ENTREZGENE, UniProtKB/TrEMBL
  G5AZ02 ENTREZGENE, UniProtKB/TrEMBL
1 to 26 of 26 rows