Cd86 (CD86 molecule) - Rat Genome Database

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Gene: Cd86 (CD86 molecule) Heterocephalus glaber
Analyze
Symbol: Cd86
Name: CD86 molecule
RGD ID: 18926207
Description: ENCODES a protein that exhibits receptor ligand activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN B cell activation (ortholog); CD40 signaling pathway (ortholog); cellular response to cytokine stimulus (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); adult T-cell leukemia/lymphoma (ortholog); FOUND IN cell surface (ortholog); centriolar satellite (ortholog); extracellular exosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: T-lymphocyte activation antigen CD86
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624912350,157 - 426,712 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624912350,201 - 432,410 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cd86
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624912350,157 - 426,712 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624912350,201 - 432,410 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CD86
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383122,055,362 - 122,121,136 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3122,055,362 - 122,121,139 (+)EnsemblGRCh38hg38GRCh38
GRCh373121,774,209 - 121,839,983 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363123,256,911 - 123,322,673 (+)NCBINCBI36Build 36hg18NCBI36
Celera3120,183,894 - 120,249,657 (+)NCBICelera
Cytogenetic Map3q13.33NCBI
HuRef3119,148,000 - 119,213,630 (+)NCBIHuRef
CHM1_13121,738,233 - 121,803,970 (+)NCBICHM1_1
T2T-CHM13v2.03124,775,351 - 124,841,114 (+)NCBIT2T-CHM13v2.0
Cd86
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391636,389,318 - 36,486,439 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1636,424,231 - 36,486,443 (-)EnsemblGRCm39 Ensembl
GRCm381636,568,956 - 36,666,158 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1636,603,869 - 36,666,081 (-)EnsemblGRCm38mm10GRCm38
MGSCv371636,603,955 - 36,666,163 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361636,523,113 - 36,585,290 (-)NCBIMGSCv36mm8
Celera1637,019,467 - 37,081,856 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1625.72NCBI
Cd86
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81177,647,565 - 77,706,178 (+)NCBIGRCr8
mRatBN7.21164,142,193 - 64,200,816 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,163,828 - 64,200,818 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1172,976,468 - 73,012,708 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01165,638,701 - 65,674,935 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01164,669,718 - 64,705,519 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01167,060,305 - 67,117,990 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1167,082,193 - 67,118,795 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01170,150,748 - 70,208,995 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41166,215,233 - 66,238,882 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11166,272,821 - 66,296,468 (-)NCBI
Celera1163,635,203 - 63,670,914 (+)NCBICelera
Cytogenetic Map11q22NCBI
Cd86
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542721,375,794 - 21,435,874 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542721,375,820 - 21,436,767 (+)NCBIChiLan1.0ChiLan1.0
CD86
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22120,006,752 - 120,072,511 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13120,011,537 - 120,077,290 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03119,151,884 - 119,217,641 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13126,059,008 - 126,124,339 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3126,059,008 - 126,124,339 (+)Ensemblpanpan1.1panPan2
CD86
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13325,256,267 - 25,318,855 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3325,256,267 - 25,318,087 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3325,281,506 - 25,343,086 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03325,491,858 - 25,554,625 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3325,491,761 - 25,553,455 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13325,289,910 - 25,351,816 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03325,332,469 - 25,394,248 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03325,890,298 - 25,952,478 (+)NCBIUU_Cfam_GSD_1.0
Cd86
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602129,038,128 - 129,107,520 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365368,414,491 - 8,481,712 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD86
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13138,427,533 - 138,504,310 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113138,427,573 - 138,504,307 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213148,055,863 - 148,130,754 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD86
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12258,741,534 - 58,805,417 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2258,741,525 - 58,805,366 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041107,540,631 - 107,604,240 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000001928   ⟹   ENSHGLP00000001882
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624912350,157 - 426,712 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000001929   ⟹   ENSHGLP00000001883
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624912350,157 - 426,712 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000001930   ⟹   ENSHGLP00000001884
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624912367,484 - 426,712 (+)Ensembl
RefSeq Acc Id: XM_004873593   ⟹   XP_004873650
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624912350,201 - 432,410 (+)NCBI
RefSeq Acc Id: XM_021251280   ⟹   XP_021106939
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624912370,429 - 432,410 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004873650 (Get FASTA)   NCBI Sequence Viewer  
  XP_021106939 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB03462 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000001882
GenBank Protein JAO00155 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004873650   ⟸   XM_004873593
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JCW0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106939   ⟸   XM_021251280
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JCW0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000001883   ⟸   ENSHGLT00000001929
RefSeq Acc Id: ENSHGLP00000001882   ⟸   ENSHGLT00000001928
RefSeq Acc Id: ENSHGLP00000001884   ⟸   ENSHGLT00000001930


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001437 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000001928 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD86_IgV UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
NCBI Gene Cd86 ENTREZGENE
PANTHER T-LYMPHOCYTE ACTIVATION ANTIGEN UniProtKB/TrEMBL
  T-LYMPHOCYTE ACTIVATION ANTIGEN CD86 UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGv UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0P6JCW0 ENTREZGENE, UniProtKB/TrEMBL