Rmdn2 (regulator of microtubule dynamics 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Rmdn2 (regulator of microtubule dynamics 2) Heterocephalus glaber
Analyze
Symbol: Rmdn2
Name: regulator of microtubule dynamics 2
RGD ID: 18919365
Description: ENCODES a protein that exhibits microtubule binding (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Lynch syndrome (ortholog); RASopathy (ortholog); FOUND IN cytosol (ortholog); Golgi apparatus (ortholog); mitotic spindle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: regulator of microtubule dynamics protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473819,533,915 - 19,624,796 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Rmdn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473819,533,915 - 19,624,796 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RMDN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38237,920,901 - 38,067,138 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl237,923,187 - 38,067,142 (+)EnsemblGRCh38hg38GRCh38
GRCh37238,152,430 - 38,294,281 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36238,031,110 - 38,147,784 (+)NCBINCBI36Build 36hg18NCBI36
Celera237,993,344 - 38,135,162 (+)NCBICelera
Cytogenetic Map2p22.2NCBI
HuRef237,892,352 - 38,034,219 (+)NCBIHuRef
CHM1_1238,081,826 - 38,223,645 (+)NCBICHM1_1
T2T-CHM13v2.0237,924,033 - 38,074,024 (+)NCBIT2T-CHM13v2.0
Rmdn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391779,886,025 - 80,000,630 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1779,919,292 - 80,000,621 (+)EnsemblGRCm39 Ensembl
GRCm381779,578,596 - 79,684,976 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1779,611,863 - 79,693,192 (+)EnsemblGRCm38mm10GRCm38
MGSCv371780,014,240 - 80,081,492 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361779,523,226 - 79,590,478 (+)NCBIMGSCv36mm8
Celera1783,926,320 - 83,993,610 (+)NCBICelera
Cytogenetic Map17E3NCBI
cM Map1750.3NCBI
Rmdn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8621,101,383 - 21,195,221 (-)NCBIGRCr8
mRatBN7.2615,372,569 - 15,443,000 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl615,375,496 - 15,441,480 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx615,677,381 - 15,739,885 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0615,999,568 - 16,062,072 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0615,495,833 - 15,558,337 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.062,215,062 - 2,292,288 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl62,216,623 - 2,280,777 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.062,199,087 - 2,268,193 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.462,440,492 - 2,514,419 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera615,046,727 - 15,107,613 (-)NCBICelera
Cytogenetic Map6q12NCBI
Rmdn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554415,716,934 - 5,774,668 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554415,710,487 - 5,776,351 (+)NCBIChiLan1.0ChiLan1.0
RMDN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21288,469,045 - 88,558,921 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A88,472,817 - 88,562,878 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A37,948,081 - 38,087,498 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A38,711,957 - 38,801,058 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A38,716,147 - 38,800,755 (+)Ensemblpanpan1.1panPan2
RMDN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11730,173,479 - 30,240,478 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1730,179,071 - 30,269,373 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1729,986,856 - 30,053,792 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01730,823,188 - 30,890,203 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1730,828,447 - 30,918,797 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11730,049,548 - 30,115,512 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01730,116,501 - 30,183,633 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01730,331,758 - 30,398,722 (+)NCBIUU_Cfam_GSD_1.0
Rmdn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629241,721,111 - 41,805,599 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936663385,288 - 471,284 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936663387,358 - 471,199 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RMDN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3102,215,140 - 102,424,775 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13102,210,367 - 102,307,355 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23108,468,326 - 108,559,987 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103220469
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11469,374,850 - 69,461,107 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1469,374,674 - 69,461,703 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604542,497,485 - 42,588,574 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004839306   ⟹   XP_004839363
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473819,534,402 - 19,624,796 (+)NCBI
RefSeq Acc Id: XM_004839307   ⟹   XP_004839364
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473819,534,794 - 19,624,796 (+)NCBI
RefSeq Acc Id: XM_004839308   ⟹   XP_004839365
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473819,533,915 - 19,624,796 (+)NCBI
RefSeq Acc Id: XM_004839309   ⟹   XP_004839366
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473819,533,917 - 19,624,796 (+)NCBI
RefSeq Acc Id: XM_004839310   ⟹   XP_004839367
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473819,533,917 - 19,610,424 (+)NCBI
RefSeq Acc Id: XM_004839311   ⟹   XP_004839368
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473819,533,916 - 19,604,204 (+)NCBI
RefSeq Acc Id: XM_021253738   ⟹   XP_021109397
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473819,533,916 - 19,624,796 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004839365   ⟸   XM_004839308
- Peptide Label: isoform X3
- UniProtKB: G5BZ88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109397   ⟸   XM_021253738
- Peptide Label: isoform X1
- UniProtKB: G5BZ88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839368   ⟸   XM_004839311
- Peptide Label: isoform X2
- UniProtKB: G5BZ88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839366   ⟸   XM_004839309
- Peptide Label: isoform X4
- UniProtKB: G5BZ88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839367   ⟸   XM_004839310
- Peptide Label: isoform X5
- UniProtKB: G5BZ88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839363   ⟸   XM_004839306
- Peptide Label: isoform X1
- UniProtKB: G5BZ88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839364   ⟸   XM_004839307
- Peptide Label: isoform X1
- UniProtKB: G5BZ88 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
InterPro RMD1-3_a_helical_rpt UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
NCBI Gene Rmdn2 ENTREZGENE
PANTHER REGULATOR OF MICROTUBULE DYNAMICS PROTEIN UniProtKB/TrEMBL
  REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 2 UniProtKB/TrEMBL
Pfam RMD1-3 UniProtKB/TrEMBL
Superfamily-SCOP TPR-like UniProtKB/TrEMBL
UniProt G5BZ88 ENTREZGENE, UniProtKB/TrEMBL