Srr (serine racemase) - Rat Genome Database

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Gene: Srr (serine racemase) Heterocephalus glaber
Analyze
Symbol: Srr
Name: serine racemase
RGD ID: 18911009
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); glycine binding (ortholog); identical protein binding (ortholog); INVOLVED IN D-serine biosynthetic process (ortholog); D-serine metabolic process (ortholog); L-serine metabolic process (ortholog); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; nonketotic hyperglycinemia pathway; ASSOCIATED WITH Animal Disease Models (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN apical part of cell (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247864,977,574 - 4,988,945 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247864,969,742 - 4,988,874 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Srr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247864,977,574 - 4,988,945 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247864,969,742 - 4,988,874 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SRR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38172,303,378 - 2,325,264 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl172,303,383 - 2,325,260 (+)EnsemblGRCh38hg38GRCh38
GRCh37172,207,237 - 2,228,558 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36172,153,998 - 2,175,303 (+)NCBINCBI36Build 36hg18NCBI36
Build 34172,153,997 - 2,175,303NCBI
Celera172,223,105 - 2,244,656 (+)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef172,102,020 - 2,123,254 (+)NCBIHuRef
CHM1_1172,215,887 - 2,237,496 (+)NCBICHM1_1
T2T-CHM13v2.0172,190,459 - 2,212,603 (+)NCBIT2T-CHM13v2.0
Srr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,794,853 - 74,818,427 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1174,797,185 - 74,816,774 (-)EnsemblGRCm39 Ensembl
GRCm381174,904,027 - 74,927,533 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,906,359 - 74,925,948 (-)EnsemblGRCm38mm10GRCm38
MGSCv371174,719,861 - 74,739,300 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,722,991 - 74,741,898 (-)NCBIMGSCv36mm8
Celera1182,412,517 - 82,431,921 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
Srr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81060,267,936 - 60,285,094 (-)NCBIGRCr8
mRatBN7.21059,769,563 - 59,786,688 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1059,769,571 - 59,787,011 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1064,417,009 - 64,433,206 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01063,922,598 - 63,938,789 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01059,384,982 - 59,401,173 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01061,756,138 - 61,772,327 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1061,756,138 - 61,772,293 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,477,874 - 61,493,655 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,217,481 - 62,234,831 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11062,231,104 - 62,248,454 (-)NCBI
Celera1058,801,057 - 58,816,824 (-)NCBICelera
Cytogenetic Map10q24NCBI
Srr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955481871,654 - 937,770 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955481919,692 - 940,066 (-)NCBIChiLan1.0ChiLan1.0
SRR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,883,643 - 9,905,686 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11711,851,013 - 11,873,067 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0172,294,440 - 2,316,244 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1172,182,839 - 2,200,704 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl172,182,839 - 2,200,704 (+)Ensemblpanpan1.1panPan2
SRR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha945,555,778 - 45,576,362 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0947,236,976 - 47,257,595 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl947,237,076 - 47,297,874 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1946,003,950 - 46,024,528 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0946,298,440 - 46,319,034 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0946,353,700 - 46,374,300 (+)NCBIUU_Cfam_GSD_1.0
Srr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560245,483,998 - 45,506,406 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365388,362,033 - 8,383,820 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1161,940,870 - 1,958,165 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl161,940,893 - 1,956,783 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605920,004,892 - 20,022,429 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004857159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01062048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01062049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH169574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000016149   ⟹   ENSHGLP00000015982
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247864,977,574 - 4,988,945 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000016150   ⟹   ENSHGLP00000015983
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247864,981,916 - 4,988,832 (+)Ensembl
RefSeq Acc Id: XM_004857159   ⟹   XP_004857216
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,759 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238098   ⟹   XP_021093757
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,977,572 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238099   ⟹   XP_021093758
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,889 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238100   ⟹   XP_021093759
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,742 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238101   ⟹   XP_021093760
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,742 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238102   ⟹   XP_021093761
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,742 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238103   ⟹   XP_021093762
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,944 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238104   ⟹   XP_021093763
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,742 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238105   ⟹   XP_021093764
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,943 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238106   ⟹   XP_021093765
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,742 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238107   ⟹   XP_021093766
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,742 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238108   ⟹   XP_021093767
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,742 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238109   ⟹   XP_021093768
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,846 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238110   ⟹   XP_021093769
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,943 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238111   ⟹   XP_021093770
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,764 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238112   ⟹   XP_021093771
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,846 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238113   ⟹   XP_021093772
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,759 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238114   ⟹   XP_021093773
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,973,990 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238115   ⟹   XP_021093774
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,742 - 4,988,874 (+)NCBI
RefSeq Acc Id: XM_021238116   ⟹   XP_021093775
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247864,969,742 - 4,988,874 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021093761   ⟸   XM_021238102
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093766   ⟸   XM_021238107
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093767   ⟸   XM_021238108
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093759   ⟸   XM_021238100
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093774   ⟸   XM_021238115
- Peptide Label: isoform X4
- UniProtKB: G5BCU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093760   ⟸   XM_021238101
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093775   ⟸   XM_021238116
- Peptide Label: isoform X4
- UniProtKB: G5BCU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093765   ⟸   XM_021238106
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093763   ⟸   XM_021238104
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093772   ⟸   XM_021238113
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004857216   ⟸   XM_004857159
- Peptide Label: isoform X4
- UniProtKB: G5BCU2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093770   ⟸   XM_021238111
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093768   ⟸   XM_021238109
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093771   ⟸   XM_021238112
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093758   ⟸   XM_021238099
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021093764   ⟸   XM_021238105
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093769   ⟸   XM_021238110
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093762   ⟸   XM_021238103
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093773   ⟸   XM_021238114
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021093757   ⟸   XM_021238098
- Peptide Label: isoform X1
RefSeq Acc Id: ENSHGLP00000015982   ⟸   ENSHGLT00000016149
RefSeq Acc Id: ENSHGLP00000015983   ⟸   ENSHGLT00000016150


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011426 Ensembl, ENTREZGENE
  ENSHGLG00100016020 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000016149 ENTREZGENE
  ENSHGLT00100070792 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1100 UniProtKB/TrEMBL
InterPro PLP-dep UniProtKB/TrEMBL
  Ser/Thr_deHydtase_PyrdxlP-BS UniProtKB/TrEMBL
  Trypto_synt_PLP_dependent UniProtKB/TrEMBL
NCBI Gene Srr ENTREZGENE
PANTHER SERINE / THREONINE RACEMASE FAMILY MEMBER UniProtKB/TrEMBL
  SERINE RACEMASE UniProtKB/TrEMBL
Pfam PALP UniProtKB/TrEMBL
PROSITE DEHYDRATASE_SER_THR UniProtKB/TrEMBL
Superfamily-SCOP SSF53686 UniProtKB/TrEMBL
UniProt G5BCU2 ENTREZGENE, UniProtKB/TrEMBL