Bgn (biglycan) - Rat Genome Database

Name: Bgn
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Bgn (biglycan) Heterocephalus glaber

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Symbol:

Bgn

Name:

biglycan

RGD ID:

18901324

Description:

ENCODES a protein that exhibits cytokine binding (ortholog); extracellular matrix binding (ortholog); glycosaminoglycan binding (ortholog); INVOLVED IN articular cartilage development (ortholog); blood vessel remodeling (ortholog); bone development (ortholog); ASSOCIATED WITH adrenoleukodystrophy (ortholog); aortic disease (ortholog); autistic disorder (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog); sarcolemma (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

biglycan preproprotein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BGN (biglycan)	NCBI	Ortholog
Mus musculus (house mouse):	Bgn (biglycan)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Bgn (biglycan)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Bgn (biglycan)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BGN (biglycan)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BGN (biglycan)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Bgn (biglycan)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BGN (biglycan)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BGN (biglycan)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624946	230,519 - 241,850 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624946	230,529 - 241,448 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adrenoleukodystrophy (ISO)

aortic disease (ISO)

autistic disorder (ISO)

autosomal hemophilia A (ISO)

Barth syndrome (ISO)

Breast Neoplasms (ISO)

cerebral creatine deficiency syndrome 1 (ISO)

Disease Progression (ISO)

dyskeratosis congenita (ISO)

Emery-Dreifuss muscular dystrophy (ISO)

Experimental Liver Cirrhosis (ISO)

Experimental Mammary Neoplasms (ISO)

factor VIII deficiency (ISO)

favism (ISO)

immunodeficiency 33 (ISO)

Meester-Loeys syndrome (ISO)

paraplegia (ISO)

periventricular nodular heterotopia (ISO)

rheumatoid arthritis (ISO)

severe congenital encephalopathy due to MECP2 mutation (ISO)

Splenomegaly (ISO)

stomach cancer (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

thoracic aortic aneurysm (ISO)

X-linked spondyloepimetaphyseal dysplasia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

articular cartilage development (ISO)

blood vessel remodeling (ISO)

bone development (ISO)

Cellular Component

cell surface (ISO)

extracellular matrix (ISO)

extracellular region (IEA)

extracellular space (IEA)

sarcolemma (ISO)

transport vesicle (ISO)

Molecular Function

cytokine binding (ISO)

extracellular matrix binding (ISO)

glycosaminoglycan binding (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:21993625	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Bgn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624946	230,519 - 241,850 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624946	230,529 - 241,448 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

BGN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	153,494,980 - 153,509,546 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	153,494,980 - 153,509,546 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	152,760,438 - 152,775,004 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	152,413,605 - 152,428,198 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	152,281,257 - 152,295,851	NCBI
Celera	X	152,994,048 - 153,008,701 (+)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
HuRef	X	141,428,414 - 141,433,357 (+)	NCBI		HuRef
CHM1_1	X	152,634,856 - 152,649,511 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	151,768,553 - 151,783,109 (+)	NCBI		T2T-CHM13v2.0

Bgn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	72,527,207 - 72,539,542 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	72,527,208 - 72,539,539 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	73,483,601 - 73,495,936 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	73,483,602 - 73,495,933 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	70,728,974 - 70,741,275 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	69,736,364 - 69,748,651 (+)	NCBI		MGSCv36	mm8
Celera	X	64,737,508 - 64,749,795 (+)	NCBI		Celera
Cytogenetic Map	X	A7.3	NCBI
cM Map	X	37.33	NCBI

Bgn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	156,348,633 - 156,360,797 (+)	NCBI		GRCr8
mRatBN7.2	X	151,197,296 - 151,209,458 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	151,197,273 - 151,209,461 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	153,338,436 - 153,350,608 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	156,901,667 - 156,913,844 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	154,573,498 - 154,585,670 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	157,319,042 - 157,331,204 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	157,319,046 - 157,331,204 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	153,067,990 - 153,080,152 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	159,380,557 - 159,393,409 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	159,453,989 - 159,466,841 (+)	NCBI
Celera	1	136,680,181 - 136,692,331 (-)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

Bgn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955580	252,139 - 263,663 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955580	252,183 - 263,179 (+)	NCBI	ChiLan1.0	ChiLan1.0

BGN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	153,534,986 - 153,549,745 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	153,538,710 - 153,553,349 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	143,045,298 - 143,059,892 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	152,931,608 - 152,946,292 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	152,931,608 - 152,946,292 (+)	Ensembl	panpan1.1		panPan2

BGN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	121,330,371 - 121,334,634 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	121,330,259 - 121,334,634 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	106,652,078 - 106,665,354 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	124,463,956 - 124,477,899 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	124,463,911 - 124,477,891 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	120,233,690 - 120,246,965 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	122,748,802 - 122,762,079 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	122,510,823 - 122,524,101 (+)	NCBI		UU_Cfam_GSD_1.0

Bgn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	118,637,802 - 118,651,947 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936809	375,543 - 389,756 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936809	375,589 - 389,718 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BGN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	124,275,305 - 124,295,445 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	124,282,048 - 124,295,450 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	141,845,604 - 141,858,856 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BGN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	127,926,018 - 127,940,485 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	127,926,009 - 127,941,164 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	65,787,635 - 65,802,224 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_004874920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021252330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AHKG01106363	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GEBF01000591	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JH168483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSHGLT00000005541 ⟹ ENSHGLP00000005470

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla_female_1.0 Ensembl	NW_004624946	230,519 - 241,850 (+)	Ensembl

RefSeq Acc Id:

XM_004874920 ⟹ XP_004874977

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624946	230,529 - 241,448 (+)	NCBI

RefSeq Acc Id:

XM_021252330 ⟹ XP_021107989

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624946	236,727 - 241,448 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_004874977	(Get FASTA)	NCBI Sequence Viewer
	XP_021107989	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EHB04330	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSHGLP00000005470
	ENSHGLP00100022480
GenBank Protein	JAO03042	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_004874977 ⟸ XM_004874920
- UniProtKB:	G5B4W9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_021107989 ⟸ XM_021252330
- UniProtKB:	G5B4W9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSHGLP00000005470 ⟸ ENSHGLT00000005541

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSHGLG00000004010	Ensembl, ENTREZGENE
	ENSHGLG00100016533	UniProtKB/TrEMBL
Ensembl Transcript	ENSHGLT00000005541	ENTREZGENE
	ENSHGLT00100022713	UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	Leu-rich_rpt	UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
	LRRNT	UniProtKB/TrEMBL
	SLRP	UniProtKB/TrEMBL
	SLRP_I_decor/aspor/byglycan	UniProtKB/TrEMBL
KEGG Report	hgl:101713153	UniProtKB/TrEMBL
NCBI Gene	Bgn	ENTREZGENE
PANTHER	AGAP008170-PA	UniProtKB/TrEMBL
	PTHR45712:SF11	UniProtKB/TrEMBL
Pfam	LRR_8	UniProtKB/TrEMBL
	LRRNT	UniProtKB/TrEMBL
PIRSF	SLRP_I	UniProtKB/TrEMBL
PROSITE	LRR	UniProtKB/TrEMBL
SMART	LRR_TYP	UniProtKB/TrEMBL
	LRRNT	UniProtKB/TrEMBL
Superfamily-SCOP	L domain-like	UniProtKB/TrEMBL
UniProt	G5B4W9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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