Ap1s2 (adaptor related protein complex 1 subunit sigma 2) - Rat Genome Database

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Gene: Ap1s2 (adaptor related protein complex 1 subunit sigma 2) Heterocephalus glaber
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Symbol: Ap1s2
Name: adaptor related protein complex 1 subunit sigma 2
RGD ID: 18899799
Description: ENCODES a protein that exhibits clathrin adaptor activity (inferred); INVOLVED IN adipose tissue development (ortholog); establishment of localization in cell (ortholog); fat cell differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Experimental Liver Cirrhosis (ortholog); Fanconi anemia (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adaptor related protein complex 1 sigma 2 subunit; AP-1 complex subunit sigma-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624829608,065 - 634,479 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624829608,065 - 637,096 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ap1s2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624829608,065 - 634,479 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624829608,065 - 637,096 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
AP1S2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X15,825,806 - 15,854,813 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX15,825,806 - 15,854,931 (-)EnsemblGRCh38hg38GRCh38
GRCh37X15,843,929 - 15,872,936 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X15,753,850 - 15,783,021 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X15,603,585 - 15,632,757NCBI
CeleraX19,961,411 - 19,990,500 (-)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX13,597,581 - 13,626,785 (-)NCBIHuRef
CHM1_1X15,874,896 - 15,904,078 (-)NCBICHM1_1
T2T-CHM13v2.0X15,408,728 - 15,437,727 (-)NCBIT2T-CHM13v2.0
Ap1s2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X162,691,427 - 162,716,662 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX162,692,013 - 162,716,662 (+)EnsemblGRCm39 Ensembl
GRCm38X163,908,454 - 163,933,666 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX163,909,017 - 163,933,666 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X160,347,092 - 160,367,478 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X159,253,265 - 159,273,651 (+)NCBIMGSCv36mm8
CeleraX147,128,574 - 147,148,961 (+)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX75.97NCBI
Ap1s2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X34,204,601 - 34,230,819 (-)NCBIGRCr8
mRatBN7.2X30,572,746 - 30,598,961 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX30,572,751 - 30,597,262 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX31,605,829 - 31,631,914 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X35,042,629 - 35,068,714 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X31,230,051 - 31,256,138 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X32,329,883 - 32,376,301 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX32,329,598 - 32,355,307 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X32,691,539 - 32,717,224 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X51,329,574 - 51,356,406 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX30,915,890 - 30,941,975 (-)NCBICelera
Cytogenetic MapXq14NCBI
Ap1s2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555192,351,754 - 2,370,650 (+)NCBIChiLan1.0ChiLan1.0
AP1S2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X17,622,529 - 17,652,391 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X17,625,917 - 17,655,154 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X8,449,885 - 8,478,932 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X15,807,475 - 15,835,938 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX15,807,476 - 15,836,172 (-)Ensemblpanpan1.1panPan2
AP1S2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X12,075,797 - 12,105,911 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX12,076,724 - 12,103,654 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX11,926,084 - 11,956,371 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X12,037,006 - 12,067,314 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX12,037,006 - 12,067,320 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X12,106,135 - 12,136,551 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X12,093,621 - 12,123,810 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X12,118,821 - 12,149,359 (-)NCBIUU_Cfam_GSD_1.0
Ap1s2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X5,251,240 - 5,289,320 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364705,257,542 - 5,289,469 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364705,260,984 - 5,301,552 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AP1S2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX12,367,795 - 12,397,677 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X12,367,785 - 12,397,672 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X13,312,013 - 13,341,898 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AP1S2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X14,283,175 - 14,310,453 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605616,136,637 - 16,164,845 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000003351   ⟹   ENSHGLP00000003296
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624829608,065 - 634,479 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000003352   ⟹   ENSHGLP00000003297
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624829608,506 - 634,479 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000003353   ⟹   ENSHGLP00000003298
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624829619,768 - 634,407 (-)Ensembl
RefSeq Acc Id: XM_004866117   ⟹   XP_004866174
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624829611,231 - 636,727 (-)NCBI
RefSeq Acc Id: XM_013066025   ⟹   XP_012921479
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624829608,065 - 634,479 (-)NCBI
RefSeq Acc Id: XM_013066026   ⟹   XP_012921480
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624829608,065 - 634,479 (-)NCBI
RefSeq Acc Id: XM_021245302   ⟹   XP_021100961
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624829611,231 - 634,479 (-)NCBI
RefSeq Acc Id: XM_021245303   ⟹   XP_021100962
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624829611,231 - 634,479 (-)NCBI
RefSeq Acc Id: XM_021245304   ⟹   XP_021100963
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624829611,231 - 637,096 (-)NCBI
RefSeq Acc Id: XR_002389669
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624829611,231 - 634,479 (-)NCBI
RefSeq Acc Id: XR_002389670
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624829608,065 - 634,479 (-)NCBI
RefSeq Acc Id: XP_012921480   ⟸   XM_013066026
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JFS1 (UniProtKB/TrEMBL),   G5C213 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012921479   ⟸   XM_013066025
- Peptide Label: isoform X2
- UniProtKB: A0AAX6QIN6 (UniProtKB/TrEMBL),   G5C213 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021100963   ⟸   XM_021245304
- Peptide Label: isoform X5
- UniProtKB: A0AAX6RYS8 (UniProtKB/TrEMBL),   G5B3T5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004866174   ⟸   XM_004866117
- Peptide Label: isoform X1
- UniProtKB: A0AAX6Q5X2 (UniProtKB/TrEMBL),   G5B3T5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021100962   ⟸   XM_021245303
- Peptide Label: isoform X4
- UniProtKB: A0AAX6RT16 (UniProtKB/TrEMBL),   G5C213 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021100961   ⟸   XM_021245302
- Peptide Label: isoform X1
- UniProtKB: A0AAX6Q5X2 (UniProtKB/TrEMBL),   G5B3T5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000003296   ⟸   ENSHGLT00000003351
Ensembl Acc Id: ENSHGLP00000003298   ⟸   ENSHGLT00000003353
Ensembl Acc Id: ENSHGLP00000003297   ⟸   ENSHGLT00000003352


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002438 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000003351 ENTREZGENE
  ENSHGLT00000003352 ENTREZGENE
Gene3D-CATH 3.30.450.60 UniProtKB/TrEMBL
InterPro AP1_sigma UniProtKB/TrEMBL
  AP_complex_ssu UniProtKB/TrEMBL
  AP_mu_sigma_su UniProtKB/TrEMBL
  Clathrin_sm-chain_CS UniProtKB/TrEMBL
  Longin-like_dom_sf UniProtKB/TrEMBL
NCBI Gene Ap1s2 ENTREZGENE
PANTHER PTHR11753 UniProtKB/TrEMBL
Pfam Clat_adaptor_s UniProtKB/TrEMBL
PIRSF AP_complex_sigma UniProtKB/TrEMBL
PROSITE CLAT_ADAPTOR_S UniProtKB/TrEMBL
Superfamily-SCOP SSF64356 UniProtKB/TrEMBL
UniProt A0A0P6JFS1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6Q5X2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QIN6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RT16 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RYS8 ENTREZGENE, UniProtKB/TrEMBL
  G5B3T5 ENTREZGENE, UniProtKB/TrEMBL
  G5C213 ENTREZGENE, UniProtKB/TrEMBL