Smoc2 (SPARC related modular calcium binding 2) - Rat Genome Database

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Gene: Smoc2 (SPARC related modular calcium binding 2) Heterocephalus glaber
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Symbol: Smoc2
Name: SPARC related modular calcium binding 2
RGD ID: 18908657
Description: ENCODES a protein that exhibits glycosaminoglycan binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of angiogenesis (ortholog); positive regulation of cell-substrate adhesion (ortholog); ASSOCIATED WITH Dentin Dysplasia, Type 1 (ortholog); Experimental Liver Cirrhosis (ortholog); schizophrenia (ortholog); FOUND IN cell periphery (ortholog); extracellular matrix (ortholog); interstitial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SPARC-related modular calcium-binding protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248504,510,598 - 4,661,056 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248504,510,700 - 4,658,579 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Smoc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248504,510,598 - 4,661,056 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248504,510,700 - 4,658,579 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SMOC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386168,441,184 - 168,667,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6168,441,151 - 168,673,445 (+)EnsemblGRCh38hg38GRCh38
GRCh376168,841,864 - 169,068,672 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366168,584,880 - 168,810,596 (+)NCBINCBI36Build 36hg18NCBI36
Build 346168,660,586 - 168,886,303NCBI
Celera6169,559,437 - 169,782,279 (+)NCBICelera
Cytogenetic Map6q27NCBI
HuRef6166,267,021 - 166,491,991 (+)NCBIHuRef
CHM1_16169,103,759 - 169,328,184 (+)NCBICHM1_1
T2T-CHM13v2.06169,784,308 - 170,014,051 (+)NCBIT2T-CHM13v2.0
Smoc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391714,499,768 - 14,625,052 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1714,499,768 - 14,625,052 (+)EnsemblGRCm39 Ensembl
GRCm381714,279,490 - 14,404,790 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1714,279,506 - 14,404,790 (+)EnsemblGRCm38mm10GRCm38
MGSCv371714,416,513 - 14,541,797 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361714,016,132 - 14,141,361 (+)NCBIMGSCv36mm8
Celera1715,080,624 - 15,205,897 (+)NCBICelera
Cytogenetic Map17A2NCBI
cM Map178.95NCBI
Smoc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8163,935,627 - 64,064,952 (+)NCBIGRCr8
mRatBN7.2155,262,472 - 55,391,804 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl155,262,530 - 55,391,693 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx160,133,640 - 60,262,572 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0168,790,717 - 68,919,413 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0162,043,596 - 62,172,525 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0156,242,289 - 56,374,106 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl156,242,346 - 56,374,120 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0157,434,118 - 57,565,436 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4153,165,792 - 53,295,145 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1153,168,675 - 53,298,175 (+)NCBI
Celera151,480,576 - 51,609,313 (+)NCBICelera
Cytogenetic Map1q12NCBI
Smoc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554114,729,706 - 4,822,140 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554114,729,753 - 4,822,140 (-)NCBIChiLan1.0ChiLan1.0
SMOC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25188,680,006 - 188,916,951 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16186,561,388 - 186,795,664 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06166,430,178 - 166,664,577 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16171,366,929 - 171,588,320 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6171,366,929 - 171,589,084 (+)Ensemblpanpan1.1panPan2
SMOC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1155,826,354 - 55,986,053 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl155,825,666 - 55,986,052 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha156,617,795 - 56,777,591 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0156,009,740 - 56,168,234 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl156,009,366 - 56,168,233 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1155,906,584 - 56,065,183 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0155,753,833 - 55,912,398 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0156,380,993 - 56,539,474 (+)NCBIUU_Cfam_GSD_1.0
Smoc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946150,202,183 - 150,342,912 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648917,454,270 - 17,594,901 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648917,454,274 - 17,594,894 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMOC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl11,193,167 - 1,332,694 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.111,193,163 - 1,332,739 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.212,133,877 - 2,217,364 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SMOC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11396,264,170 - 96,477,393 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1396,264,181 - 96,477,491 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604068,107,603 - 68,398,081 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000003123   ⟹   ENSHGLP00000003068
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248504,510,598 - 4,661,056 (+)Ensembl
RefSeq Acc Id: XM_004868836   ⟹   XP_004868893
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248504,510,700 - 4,658,579 (+)NCBI
RefSeq Acc Id: XM_004868837   ⟹   XP_004868894
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248504,510,700 - 4,658,579 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004868893 (Get FASTA)   NCBI Sequence Viewer  
  XP_004868894 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10378 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003068
  ENSHGLP00000060685
GenBank Protein JAO03297 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004868893   ⟸   XM_004868836
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JYH5 (UniProtKB/TrEMBL),   G5BM67 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004868894   ⟸   XM_004868837
- Peptide Label: isoform X2
- UniProtKB: G5BM67 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000003068   ⟸   ENSHGLT00000003123


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002295 Ensembl, ENTREZGENE
  ENSHGLG00000044254 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000003123 ENTREZGENE
  ENSHGLT00000083260 UniProtKB/TrEMBL
Gene3D-CATH 3.30.60.30 UniProtKB/TrEMBL
  4.10.800.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro Dev_reg/Prot_inhib UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  Kazal_dom UniProtKB/TrEMBL
  Kazal_dom_sf UniProtKB/TrEMBL
  SMOC2_EC UniProtKB/TrEMBL
  SPARC/Testican_Ca-bd-dom UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
  Thyroglobulin_1_sf UniProtKB/TrEMBL
KEGG Report hgl:101726146 UniProtKB/TrEMBL
NCBI Gene Smoc2 ENTREZGENE
PANTHER SECRETED MODULAR CALCIUM-BINDING PROTEIN UniProtKB/TrEMBL
  SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 2 UniProtKB/TrEMBL
Pfam Kazal_2 UniProtKB/TrEMBL
  SPARC_Ca_bdg UniProtKB/TrEMBL
  Thyroglob_assoc UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  KAZAL_2 UniProtKB/TrEMBL
  THYROGLOBULIN_1_1 UniProtKB/TrEMBL
  THYROGLOBULIN_1_2 UniProtKB/TrEMBL
SMART KAZAL UniProtKB/TrEMBL
  SM00211 UniProtKB/TrEMBL
Superfamily-SCOP SSF100895 UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF57610 UniProtKB/TrEMBL
UniProt A0A0P6JYH5 ENTREZGENE, UniProtKB/TrEMBL
  G5BM67 ENTREZGENE, UniProtKB/TrEMBL