Pdzrn3 (PDZ domain containing ring finger 3) - Rat Genome Database

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Gene: Pdzrn3 (PDZ domain containing ring finger 3) Heterocephalus glaber
Analyze
Symbol: Pdzrn3
Name: PDZ domain containing ring finger 3
RGD ID: 18920745
Description: ENCODES a protein that exhibits ubiquitin-protein transferase activity (ortholog); INVOLVED IN neuromuscular junction development (inferred); protein ubiquitination (inferred); ASSOCIATED WITH Childhood Schizophrenia (ortholog); Dwarfism (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN neuromuscular junction (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase PDZRN3; PDZ domain-containing RING finger protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247737,900,934 - 8,144,003 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247737,901,560 - 8,144,455 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pdzrn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247737,900,934 - 8,144,003 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247737,901,560 - 8,144,455 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PDZRN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38373,382,431 - 73,624,941 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl373,382,431 - 73,624,941 (-)EnsemblGRCh38hg38GRCh38
GRCh37373,431,582 - 73,674,092 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36373,514,342 - 73,756,762 (-)NCBINCBI36Build 36hg18NCBI36
Celera373,365,735 - 73,608,750 (-)NCBICelera
Cytogenetic Map3p13NCBI
HuRef373,434,331 - 73,676,506 (-)NCBIHuRef
CHM1_1373,385,013 - 73,627,407 (-)NCBICHM1_1
T2T-CHM13v2.0373,423,926 - 73,666,429 (-)NCBIT2T-CHM13v2.0
Pdzrn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396101,126,568 - 101,354,858 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6101,126,570 - 101,354,858 (-)EnsemblGRCm39 Ensembl
GRCm386101,149,607 - 101,377,897 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6101,149,609 - 101,377,897 (-)EnsemblGRCm38mm10GRCm38
MGSCv376101,099,601 - 101,327,891 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366101,115,712 - 101,343,995 (-)NCBIMGSCv36mm8
Celera6103,016,258 - 103,244,142 (-)NCBICelera
Cytogenetic Map6D3NCBI
cM Map646.95NCBI
Pdzrn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84135,327,082 - 135,553,294 (-)NCBIGRCr8
mRatBN7.24133,770,736 - 133,996,959 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4133,770,736 - 133,996,959 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4139,182,993 - 139,416,031 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04134,963,779 - 135,196,808 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04133,584,382 - 133,817,407 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04133,717,139 - 133,951,282 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4133,717,139 - 133,951,264 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04198,194,465 - 198,429,457 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44136,044,210 - 136,254,969 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14136,260,810 - 136,311,636 (-)NCBI
Celera4122,607,053 - 122,831,741 (-)NCBICelera
Cytogenetic Map4q34NCBI
Pdzrn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542114,648,524 - 14,877,822 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542114,648,436 - 14,878,759 (+)NCBIChiLan1.0ChiLan1.0
PDZRN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2273,337,666 - 73,581,399 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1373,342,455 - 73,586,188 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0373,322,613 - 73,565,929 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1375,245,623 - 75,488,415 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl375,246,558 - 75,488,499 (-)Ensemblpanpan1.1panPan2
PDZRN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12018,621,960 - 18,859,620 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2018,622,069 - 18,859,550 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2018,594,042 - 18,830,979 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02018,656,854 - 18,893,815 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2018,656,915 - 18,893,825 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12018,344,911 - 18,581,831 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02018,685,052 - 18,922,922 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02018,750,258 - 18,987,822 (+)NCBIUU_Cfam_GSD_1.0
Pdzrn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049424,218,675 - 4,420,201 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366034,218,212 - 4,420,087 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366034,218,675 - 4,423,450 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDZRN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1354,659,589 - 54,904,809 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11354,659,657 - 54,904,742 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21360,422,724 - 60,650,319 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDZRN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12234,325,208 - 34,567,748 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2234,326,144 - 34,567,633 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041132,201,578 - 132,443,428 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000004246   ⟹   ENSHGLP00000004188
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247737,900,934 - 8,144,003 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000004247   ⟹   ENSHGLP00000004189
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247737,900,934 - 8,028,202 (-)Ensembl
RefSeq Acc Id: XM_004854215   ⟹   XP_004854272
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247737,901,560 - 8,144,455 (-)NCBI
RefSeq Acc Id: XM_013075654   ⟹   XP_012931108
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247737,901,560 - 7,948,148 (-)NCBI
RefSeq Acc Id: XM_013075656   ⟹   XP_012931110
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247737,901,560 - 8,028,047 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004854272 (Get FASTA)   NCBI Sequence Viewer  
  XP_012931108 (Get FASTA)   NCBI Sequence Viewer  
  XP_012931110 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB07252 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000004188
  ENSHGLP00000004189
Reference Protein Sequences
RefSeq Acc Id: XP_004854272   ⟸   XM_004854215
- Peptide Label: isoform X1
RefSeq Acc Id: XP_012931110   ⟸   XM_013075656
- Peptide Label: isoform X3
- UniProtKB: G5BD91 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012931108   ⟸   XM_013075654
- Peptide Label: isoform X2
- UniProtKB: G5BD91 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000004188   ⟸   ENSHGLT00000004246
RefSeq Acc Id: ENSHGLP00000004189   ⟸   ENSHGLT00000004247


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003072 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000004246 ENTREZGENE
  ENSHGLT00000004247 ENTREZGENE
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  6.20.370.60 UniProtKB/TrEMBL
InterPro PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
NCBI Gene Pdzrn3 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE PDZRN3 UniProtKB/TrEMBL
  PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
PROSITE PDZ UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
Superfamily-SCOP PDZ domain-like UniProtKB/TrEMBL
UniProt G5BD91 ENTREZGENE, UniProtKB/TrEMBL