Asns (asparagine synthetase (glutamine-hydrolyzing)) - Rat Genome Database

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Gene: Asns (asparagine synthetase (glutamine-hydrolyzing)) Heterocephalus glaber
Analyze
Symbol: Asns
Name: asparagine synthetase (glutamine-hydrolyzing)
RGD ID: 18913044
Description: ENCODES a protein that exhibits asparagine synthase (glutamine-hydrolyzing) activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); asparagine biosynthetic process (ortholog); cellular response to glucose starvation (ortholog); PARTICIPATES IN Canavan disease pathway; ASSOCIATED WITH Asparagine Synthetase Deficiency (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: asparagine synthetase (glutamine-hydrolyzing) isoform c; asparagine synthetase [glutamine-hydrolyzing]
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248134,641,372 - 4,661,778 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248134,642,420 - 4,661,362 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Asns
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248134,641,372 - 4,661,778 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248134,642,420 - 4,661,362 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ASNS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38797,851,677 - 97,928,441 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl797,851,677 - 97,872,542 (-)EnsemblGRCh38hg38GRCh38
GRCh37797,480,989 - 97,557,753 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36797,319,376 - 97,339,732 (-)NCBINCBI36Build 36hg18NCBI36
Build 34797,126,093 - 97,146,434NCBI
Celera792,176,132 - 92,196,562 (-)NCBICelera
Cytogenetic Map7q21.3NCBI
HuRef792,082,173 - 92,102,489 (-)NCBIHuRef
CHM1_1797,411,399 - 97,431,825 (-)NCBICHM1_1
T2T-CHM13v2.0799,081,731 - 99,158,507 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2796,803,932 - 96,824,039 (-)NCBI
Asns
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3967,675,169 - 7,693,209 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl67,675,169 - 7,693,254 (-)EnsemblGRCm39 Ensembl
GRCm3867,675,165 - 7,693,209 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl67,675,169 - 7,693,254 (-)EnsemblGRCm38mm10GRCm38
MGSCv3767,625,171 - 7,643,182 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3667,625,171 - 7,643,182 (-)NCBIMGSCv36mm8
Celera67,815,329 - 7,836,615 (-)NCBICelera
Cytogenetic Map6A1NCBI
cM Map63.31NCBI
Asns
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8436,752,061 - 36,769,970 (-)NCBIGRCr8
mRatBN7.2435,784,995 - 35,803,474 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl435,785,237 - 35,803,423 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx440,744,478 - 40,761,832 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0436,670,681 - 36,688,035 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0435,091,137 - 35,108,468 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0433,742,876 - 33,761,106 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl433,743,364 - 33,761,163 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0433,608,301 - 33,626,631 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4432,758,866 - 32,776,220 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1432,877,146 - 32,895,094 (-)NCBI
Celera431,290,059 - 31,307,413 (-)NCBICelera
Cytogenetic Map4q21NCBI
ASNS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26115,697,208 - 115,771,830 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17163,961,837 - 164,036,463 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0789,811,363 - 89,831,733 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17103,392,540 - 103,413,035 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7103,392,540 - 103,413,046 (-)Ensemblpanpan1.1panPan2
ASNS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11422,718,020 - 22,734,109 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1422,718,042 - 22,734,054 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1422,293,460 - 22,309,559 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01422,536,829 - 22,552,941 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1422,535,259 - 22,552,931 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11422,683,018 - 22,699,299 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01422,417,885 - 22,434,146 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01422,679,813 - 22,695,891 (-)NCBIUU_Cfam_GSD_1.0
Asns
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511836,008,688 - 36,029,092 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365852,834,008 - 2,855,387 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365852,834,202 - 2,854,740 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASNS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl977,318,213 - 77,343,035 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1977,318,341 - 77,336,290 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2984,880,365 - 85,078,501 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ASNS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12151,244,514 - 51,264,694 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2151,247,742 - 51,265,241 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604253,107,858 - 53,128,042 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000001939   ⟹   ENSHGLP00000001893
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248134,641,372 - 4,661,778 (-)Ensembl
RefSeq Acc Id: XM_021242851   ⟹   XP_021098510
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248134,642,420 - 4,660,809 (-)NCBI
RefSeq Acc Id: XM_021242853   ⟹   XP_021098512
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248134,642,420 - 4,661,362 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021098510 (Get FASTA)   NCBI Sequence Viewer  
  XP_021098512 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10097 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000001893
  ENSHGLP00100026457
GenBank Protein JAO02694 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021098512   ⟸   XM_021242853
- UniProtKB: G5BLD6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098510   ⟸   XM_021242851
- UniProtKB: G5BLD6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000001893   ⟸   ENSHGLT00000001939


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001445 Ensembl, ENTREZGENE
  ENSHGLG00100019398 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000001939 ENTREZGENE
  ENSHGLT00100026725 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.620 UniProtKB/TrEMBL
  3.60.20.10 UniProtKB/TrEMBL
InterPro Asn_synth_AEB UniProtKB/TrEMBL
  Asn_synthase UniProtKB/TrEMBL
  AsnB_N UniProtKB/TrEMBL
  GATase_2_dom UniProtKB/TrEMBL
  Ntn_hydrolases_N UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
KEGG Report hgl:101704060 UniProtKB/TrEMBL
NCBI Gene Asns ENTREZGENE
PANTHER ASPARAGINE SYNTHETASE UniProtKB/TrEMBL
  ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING] UniProtKB/TrEMBL
Pfam Asn_synthase UniProtKB/TrEMBL
  GATase_7 UniProtKB/TrEMBL
PIRSF Asn_synthetase_glu-h UniProtKB/TrEMBL
PROSITE GATASE_TYPE_2 UniProtKB/TrEMBL
Superfamily-SCOP Adenine nucleotide alpha hydrolases-like UniProtKB/TrEMBL
  SSF56235 UniProtKB/TrEMBL
UniProt G5BLD6 ENTREZGENE, UniProtKB/TrEMBL