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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
(2R,3S,2'R)-nadolol +   
(R,R)-asenapine maleate +  
(S)-timolol (anhydrous) +   
(S)-timolol hemihydrate 
(S)-timolol maleate 
(S,S)-asenapine maleate +  
(S,S,S)-nicotianamine 
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate 
2-\{[(2E)-3-iodoprop-2-en-1-yl](propyl)amino\}tetralin-7-ol maleate 
2-hydroxy-17beta-estradiol +   
2-hydroxyoleic acid 
2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 
2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine 
3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol hydrochloride 
4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate  
4-hydroxychalcone  
4-phenylbutyric acid  
5-aminolevulinic acid +   
5-aminolevulinic acid hydrochloride 
6-O-galloyl-beta-D-glucose 
abiraterone acetate 
acebutolol  
acebutolol hydrochloride 
acemetacin  
acetophenazine dimaleate 
ACT-132577 +   
adefovir pivoxil  
afatinib dimaleate 
ajmalicine  
Alacepril 
alfuzosin +   
aliskiren +   
aliskiren fumarate 
alpha-methyl-L-dopa +   
alpha-methyl-L-dopa ethyl ester 
alpha-methyl-L-tyrosine 
alpha-N-dichloroacetyl-p-aminophenylserinol 
alprenolol +   
amifostine  
amlodipine +   
amlodipine benzenesulfonate +  
amodiaquine +   
ampiroxicam 
ancitabine  
aripiprazole lauroxil 
atenolol +   
auraptene  
azaribine  
azatadine maleate 
azathioprine  
azilsartan +   
azilsartan kamedoxomil 
azilsartan medoxomil 
bacampicillin +  
baicalin  
balsalazide +   
bambuterol +   
bambuterol hydrochloride +  
BAY 41-2272 
beclomethasone dipropionate 
benazepril  
benazepril hydrochloride 
benazeprilat +   
bendroflumethiazide +   
benzthiazide 
bepridil +   
beta-aminoarteether maleate 
betaxolol +   
betaxolol hydrochloride +  
bethanidine +  
bethanidine sulfate 
bevantolol +   
bevantolol hydrochloride +  
BGT226 
bimatoprost 
bisoprolol +   
bitolterol +  
bopindolol  
bosentan +   
bretylium +   
bretylium tosylate  
brimonidine +   
brompheniramine maleate +  
butane-1,4-diol +   
Byvalson 
cabozantinib malate 
candesartan  
capecitabine  
captopril +  
carbimazole  
carbinoxamine maleate +  
carmoxirole  
carmoxirole hydrochloride 
carphenazine maleate 
carteolol  
carteolol hydrochloride 
carvedilol  
cefamandole nafate 
cefditoren pivoxil 
cefotiam hexetil dihydrochloride 
cefotiam hexetil ester +  
cefpodoxime proxetil 
ceftaroline fosamil +  
ceftaroline fosamil acetate +  
ceftaroline fosamil acetate monohydrate 
ceftobiprole medocaril 
CGP 78608 hydrochloride 
chlorothiazide 
cilnidipine  
cinaciguat 
cleistanthin A 
cleistanthin B +  
clonidine +   
clorazepate monopotassium +  
clorazepic acid 
codeine +   
colistimethate 
colistimethate sodium 
corilagin  
cyclothiazide  
dabigatran etexilate 
dabigatran etexilate methanesulfonate 
dacarbazine  
debrisoquin +   
dextilidine +  
diazoxide  
diltiazem  
diltiazem hydrochloride 
dipivefrin 
dipotassium clorazepate 
dirithromycin 
domperidone maleate 
dorzolamide +   
dorzolamide hydrochloride  
doxazosin +   
doxifluridine  
droxicam 
droxidopa 
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor +   
enalapril +   
enalapril maleate 
The maleic acid salt of enalapril. It contains one molecule of maleic acid for each molecule of enalapril. Following oral administration, the ethyl ester group of enalapril is hydrolysed to afford the corresponding carboxylic acid, enalaprilat, an angiotensin-converting enzyme (ACE) inhibitor. Enalapril is thus a prodrug for enalaprilat (which, unlike enalapril, is not absorbed by mouth), and its maleate is used in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients with nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients.
enalaprilat (anhydrous) +   
enalaprilat dihydrate  
eplerenone  
eprosartan +  
eprosartan methanesulfonate 
ergometrine maleate 
etanidazole  
ethionamide +   
ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate 
famciclovir 
felodipine  
fenoldopam  
fingolimod +  
fingolimod hydrochloride  
flucytosine  
fludarabine phosphate 
fluprostenol +   
fluticasone furoate +  
forasartan 
forskolin +   
fosamprenavir 
fosaprepitant 
fosaprepitant dimeglumine 
Fosfluconazole 
fosinopril  
fosinopril sodium 
fosinoprilat +   
gabapentin enacarbil 
gemcitabine +   
grayanotoxin I 
guanadrel 
guanadrel sulfate 
guanethidine +   
guanethidine monosulfate +  
guanethidine sulfate 
heroin  
hydralazine +   
hydralazine hydrochloride 
hydrochlorothiazide  
hydroflumethiazide 
imidapril +   
imidaprilat  
indacaterol maleate +  
indanomycin 
indapamide  
irbesartan  
irinotecan  
irinotecan hydrochloride (anhydrous) +  
irinotecan hydrochloride hydrate 
isavuconazonium +  
isavuconazonium sulfate 
isoamyl nitrite 
isopropyl unoprostone 
ixazomib citrate 
kaempferide +   
ketanserin  
L-dopa +  
labetalol  
lamivudine  
latanoprost  
latanoprost free acid +   
leflunomide  
lefradafiban 
lisinopril +   
lisinopril dihydrate  
lisuride maleate 
lofexidine 
losartan +   
lovastatin +   
loxoprofen +   
lucanthone +   
macitentan  
mestranol  
metamizole 
metamizole sodium  
methiothepin maleate 
methyl 5-aminolevulinate +  
methyl 5-aminolevulinate hydrochloride 
metipranolol  
metipranolol hydrochloride 
metolazone  
metoprolol  
metronidazole +   
metronidazole benzoate 
metronidazole hydrochloride 
midodrine  
minoxidil  
morin  
mycophenolate mofetil 
myrophine +  
N(1),N(8)-bis-(dihydrocaffeoyl)spermidine 
N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-methylquipazine dimaleate 
nabumetone  
nadolol  
naproxcinod 
nebivolol  
nebivolol hydrochloride +  
nelarabine 
nepafenac 
nimodipine  
nisoldipine  
nitrendipine  
nitroglycerin  
nitrosulindac 
norverapamil  
O-(cyclohexanecarbonyl)lysergol maleate 
O-formylcefamandole 
oleuropein +   
olmesartan  
olsalazine 
olsalazine sodium 
oseltamivir +   
palmitoyl ethanolamide  
parecoxib  
paroxetine maleate 
pasireotide aspartate 
penamecillin 
pentolinium tartrate  
perindopril  
perindopril arginine +  
perindopril erbumine 
perindoprilat 
perphenazine maleate 
pindolol +   
pivampicillin 
pivmecillinam +  
pizotifen maleate 
praliciguat 
prasugrel 
pratosartan 
prazosin +   
prednisone +   
Prestalia 
prochlorperazine maleate 
proglumetacin +  
proglumetacin dimaleate 
propranolol +   
psilocybin 
psilocybin(1-) 
pyrazinecarboxamide  
quercetin 3-O-alpha-(6'''-caffeoylglucosyl-beta-1,2-rhamnoside) 
quinapril  
quinapril hydrochloride 
quinaprilat  
quinethazone 
ramipril  
ramiprilat  
rescinnamine  
reserpine  
rilpivirine hydrochloride +  
riociguat  
rolitetracycline 
rosiglitazone maleate 
rottlerin  
rubitecan  
salicin +   
salsalate  
SB 224289 hydrochloride 
selexipag 
simvastatin  
sodium nitrite  
sodium phenylbutyrate 
sofosbuvir +  
soyasaponin III 
spirapril  
spiraprilat +   
spironolactone  
sulfanegen 
sulindac +   
suxibuzone  
talampicillin +  
tazarotene  
tedizolid phosphate 
tegaserod maleate 
telmisartan  
temozolomide  
tenofovir alafenamide 
tenofovir alafenamide fumarate +  
tenofovir disoproxil +   
tenofovir disoproxil fumarate  
terazosin +   
thiethylperazine maleate 
tiazofurine  
tienilic acid  
tilidine 
tolazoline  
torasemide 
trandolapril  
trandolaprilat 
travoprost 
treprostinil +   
tributyrin  
trichlormethiazide  
trifluoperazine dimaleate 
trimethaphan +   
trimethaphan camsylate 
trimipramine maleate 
tris maleate 
unoprostone +  
uracil +   
uridine triacetate 
valganciclovir 
valsartan +   
verapamil  
vericiguat 
vincamine  
visnagin 
ximelagatran  
zofenopril 
zofenopril calcium 
zofenoprilat 
zofenoprilat arginine 

Synonyms
Exact Synonyms: N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline (2Z)-but-2-enedioate
Related Synonyms: (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline maleate (1:1) ;   Formula=C24H32N2O9 ;   InChI=1S/C20H28N2O5.C4H4O4/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25;5-3(6)1-2-4(7)8/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,16-,17-;/m0./s1 ;   InChIKey=OYFJQPXVCSSHAI-QFPUQLAESA-N ;   N-((S)-1-ethoxycarbonyl-3-phenylpropyl)-L-alanyl-L-proline maleate (1:1) ;   N-{N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl}-L-proline hydrogen maleate ;   SMILES=OC(=O)\\C=C/C(O)=O.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O ;   enalapril hydrogen maleate
Xrefs: Beilstein:3645274 "Beilstein" ;   CAS:76095-16-4 "ChemIDplus" ;   CAS:76095-16-4 "KEGG DRUG" ;   DrugBank:DB00584 ;   KEGG:D00621 ;   VSDB:2974

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.