CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: azathioprine
Accession: CHEBI:2948
browse the term
Definition: A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Synonyms: exact_synonym: 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
related_synonym: 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine; 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine; Formula=C9H7N7O2S; Imuran (TN); InChI=1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13); InChIKey=LMEKQMALGUDUQG-UHFFFAOYSA-N; SMILES=Cn1cnc(c1Sc1ncnc2nc[nH]c12)[N+]([O-])=O
xref: CAS:446-86-6; DrugBank:DB00993; Drug_Central:269; KEGG:C06837; KEGG:D00238
xref_mesh: MESH:D001379
xref: PMID:11064448; PMID:15199672; PMID:15476481; PMID:15628319; PMID:15973722; PMID:16344342; PMID:16397313; PMID:16764353; PMID:16954801; PMID:17381669; PMID:17970886; PMID:18008354; PMID:18336531; PMID:19243907; PMID:20080917; PMID:25248004; PMID:25314066; PMID:25440430; PMID:25443086; PMID:25581826; PMID:25641386; PMID:28166217; PMID:8738760; PMID:9273463; PMID:9345422; Reaxys:1225351; Wikipedia:Azathioprine
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Abcb11
ATP binding cassette subfamily B member 11
decreases expression
EXP
Azathioprine results in decreased expression of ABCB11 mRNA
CTD
PMID:27765674
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcb1a
ATP binding cassette subfamily B member 1A
affects response to substance
ISO
ABCB1 gene polymorphism affects the susceptibility to Azathioprine
CTD
PMID:17262810
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcb4
ATP binding cassette subfamily B member 4
increases expression
EXP
Azathioprine results in increased expression of ABCB4 mRNA
CTD
PMID:27765674
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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Abcc2
ATP binding cassette subfamily C member 2
increases expression
EXP ISO
Azathioprine results in increased expression of ABCC2 mRNA
CTD
PMID:22623647 PMID:27765674
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc3
ATP binding cassette subfamily C member 3
increases expression
EXP
Azathioprine results in increased expression of ABCC3 mRNA
CTD
PMID:27765674
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcc4
ATP binding cassette subfamily C member 4
increases expression
EXP
Azathioprine results in increased expression of ABCC4 mRNA
CTD
PMID:27765674
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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Abcg2
ATP binding cassette subfamily G member 2
decreases expression
EXP
Azathioprine results in decreased expression of ABCG2 mRNA
CTD
PMID:27765674
NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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Abcg5
ATP binding cassette subfamily G member 5
decreases expression
EXP
Azathioprine results in decreased expression of ABCG5 mRNA
CTD
PMID:27765674
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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Abhd4
abhydrolase domain containing 4, N-acyl phospholipase B
increases expression
ISO
Azathioprine results in increased expression of ABHD4 mRNA
CTD
PMID:22623647
NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
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Acat2
acetyl-CoA acetyltransferase 2
decreases expression
ISO
Azathioprine results in decreased expression of ACAT2 mRNA
CTD
PMID:22623647
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Ace2
angiotensin converting enzyme 2
increases expression
ISO
Azathioprine results in increased expression of ACE2 mRNA
CTD
PMID:32808185
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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Ackr3
atypical chemokine receptor 3
decreases expression
ISO
Azathioprine results in decreased expression of ACKR3 mRNA
CTD
PMID:19192274
NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
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Acsl5
acyl-CoA synthetase long-chain family member 5
increases expression
ISO
Azathioprine results in increased expression of ACSL5 mRNA
CTD
PMID:22623647
NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
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Adm
adrenomedullin
increases expression
ISO
Azathioprine results in increased expression of ADM mRNA
CTD
PMID:22623647
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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Adora2a
adenosine A2a receptor
decreases expression
ISO
Azathioprine results in decreased expression of ADORA2A mRNA
CTD
PMID:19192274
NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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Ager
advanced glycosylation end product-specific receptor
increases expression
ISO
Azathioprine results in increased expression of AGER mRNA
CTD
PMID:24184165
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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Akr1b10
aldo-keto reductase family 1 member B10
increases expression
ISO
Azathioprine results in increased expression of AKR1B10 mRNA
CTD
PMID:22623647 PMID:26198647
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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Akr1c1
aldo-keto reductase family 1, member C1
increases expression
ISO
Azathioprine results in increased expression of AKR1C1 mRNA
CTD
PMID:22623647
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akr1c2
aldo-keto reductase family 1, member C2
increases expression
ISO
Azathioprine results in increased expression of AKR1C2 mRNA
CTD
PMID:22623647 PMID:26198647
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Akr1d1
aldo-keto reductase family 1, member D1
decreases expression
ISO
Azathioprine results in decreased expression of AKR1D1 mRNA
CTD
PMID:22623647
NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
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Akt1
AKT serine/threonine kinase 1
multiple interactions
ISO
Azathioprine inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]
CTD
PMID:23958494
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alb
albumin
multiple interactions
EXP
[Carbon Tetrachloride co-treated with Azathioprine] results in decreased expression of ALB protein
CTD
PMID:8614026
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Aldh18a1
aldehyde dehydrogenase 18 family, member A1
decreases expression
ISO
Azathioprine results in decreased expression of ALDH18A1 mRNA
CTD
PMID:22623647
NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
increases expression
EXP
Azathioprine results in increased expression of ALDH1A1 mRNA
CTD
PMID:28138970
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldh1l1
aldehyde dehydrogenase 1 family, member L1
increases expression
ISO
Azathioprine results in increased expression of ALDH1L1 mRNA
CTD
PMID:22623647
NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465
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Aldh7a1
aldehyde dehydrogenase 7 family, member A1
decreases expression
ISO
Azathioprine results in decreased expression of ALDH7A1 mRNA
CTD
PMID:22623647
NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
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Aldh8a1
aldehyde dehydrogenase 8 family, member A1
decreases expression
ISO
Azathioprine results in decreased expression of ALDH8A1 mRNA
CTD
PMID:22623647
NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
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Amigo2
adhesion molecule with Ig like domain 2
decreases expression
ISO
Azathioprine results in decreased expression of AMIGO2 mRNA
CTD
PMID:19192274
NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695
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Ang
angiogenin
decreases expression
ISO
Azathioprine results in decreased expression of ANG mRNA
CTD
PMID:22623647
NCBI chr15:24,312,711...24,323,361
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Ankrd40
ankyrin repeat domain 40
increases expression
EXP
Azathioprine results in increased expression of TMPRSS2 mRNA
CTD
PMID:32808185
NCBI chr10:79,282,075...79,295,322
Ensembl chr10:79,282,075...79,295,320 Ensembl chr10:79,282,075...79,295,320
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Anln
anillin, actin binding protein
decreases expression
ISO
Azathioprine results in decreased expression of ANLN mRNA
CTD
PMID:22623647
NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
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Antxr1
ANTXR cell adhesion molecule 1
increases expression
ISO
Azathioprine results in increased expression of ANTXR1 mRNA
CTD
PMID:19192274
NCBI chr 4:119,590,770...119,778,232
Ensembl chr 4:119,590,771...119,778,232
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Antxr2
ANTXR cell adhesion molecule 2
increases expression
ISO
Azathioprine results in increased expression of ANTXR2 mRNA
CTD
PMID:22623647
NCBI chr14:11,541,718...11,682,110
Ensembl chr14:11,541,772...11,682,094
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Aox1
aldehyde oxidase 1
increases expression
ISO
Azathioprine results in increased expression of AOX1 mRNA
CTD
PMID:19192274
NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
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Apoc3
apolipoprotein C3
decreases expression
ISO
Azathioprine results in decreased expression of APOC3 mRNA
CTD
PMID:22623647
NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
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Aqp11
aquaporin 11
decreases expression
ISO
Azathioprine results in decreased expression of AQP11 mRNA
CTD
PMID:22623647
NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725
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Aqp3
aquaporin 3 (Gill blood group)
increases expression
ISO
Azathioprine results in increased expression of AQP3 mRNA
CTD
PMID:22623647
NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
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Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
increases expression
ISO
Azathioprine results in increased expression of ARAP2 mRNA
CTD
PMID:22623647
NCBI chr14:46,717,657...46,917,326
Ensembl chr14:46,718,760...46,917,154
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Arhgap11a
Rho GTPase activating protein 11A
decreases expression
ISO
Azathioprine results in decreased expression of ARHGAP11A mRNA
CTD
PMID:22623647
NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559
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Arhgap27
Rho GTPase activating protein 27
increases expression
ISO
Azathioprine results in increased expression of ARHGAP27 mRNA
CTD
PMID:22623647
NCBI chr10:88,280,470...88,313,225
Ensembl chr10:88,280,455...88,313,185
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Arrdc2
arrestin domain containing 2
increases expression
ISO
Azathioprine results in increased expression of ARRDC2 mRNA
CTD
PMID:22623647
NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029
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Asb9
ankyrin repeat and SOCS box-containing 9
decreases expression
ISO
Azathioprine results in decreased expression of ASB9 mRNA
CTD
PMID:22623647
NCBI chr X:29,956,576...30,001,436
Ensembl chr X:29,956,576...30,001,105
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Asns
asparagine synthetase (glutamine-hydrolyzing)
decreases expression
ISO
Azathioprine results in decreased expression of ASNS mRNA
CTD
PMID:19192274
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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Aspm
assembly factor for spindle microtubules
decreases expression
ISO
Azathioprine results in decreased expression of ASPM mRNA
CTD
PMID:22623647
NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
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Atad2
ATPase family, AAA domain containing 2
decreases expression
ISO
Azathioprine results in decreased expression of ATAD2 mRNA
CTD
PMID:22623647
NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738
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Atg2a
autophagy related 2A
increases expression
ISO
Azathioprine results in increased expression of ATG2A mRNA
CTD
PMID:22623647
NCBI chr 1:203,542,559...203,562,242
Ensembl chr 1:203,542,559...203,562,242
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Atp6v0e2
ATPase, H+ transporting V0 subunit e2
decreases expression
ISO
Azathioprine results in decreased expression of ATP6V0E2 mRNA
CTD
PMID:22623647
NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777
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Aurka
aurora kinase A
decreases expression
ISO
Azathioprine results in decreased expression of AURKA mRNA
CTD
PMID:22623647
NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
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Aurkb
aurora kinase B
decreases expression
ISO
Azathioprine results in decreased expression of AURKB mRNA
CTD
PMID:22623647
NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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Baiap2l1
BAR/IMD domain containing adaptor protein 2 like 1
increases expression
ISO
Azathioprine results in increased expression of BAIAP2L1 mRNA
CTD
PMID:22623647
NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928
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Bard1
BRCA1 associated RING domain 1
decreases expression
ISO
Azathioprine results in decreased expression of BARD1 mRNA
CTD
PMID:22623647
NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
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Bcar1
BCAR1 scaffold protein, Cas family member
increases expression
ISO
Azathioprine results in increased expression of BCAR1 mRNA
CTD
PMID:22623647
NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907
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Bcl2a1
BCL2-related protein A1
decreases expression
ISO
Azathioprine results in decreased expression of BCL2A1 mRNA
CTD
PMID:19192274
NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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Bcl2l1
Bcl2-like 1
decreases expression
ISO
Azathioprine results in decreased expression of BCL2L1 mRNA; Azathioprine results in decreased expression of BCL2L1 protein
CTD
PMID:12697733
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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Birc5
baculoviral IAP repeat-containing 5
decreases expression
ISO
Azathioprine results in decreased expression of BIRC5 mRNA
CTD
PMID:22623647
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Bora
bora, aurora kinase A activator
decreases expression
ISO
Azathioprine results in decreased expression of BORA mRNA
CTD
PMID:22623647
NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322
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Brca2
BRCA2, DNA repair associated
decreases expression
ISO
Azathioprine results in decreased expression of BRCA2 mRNA
CTD
PMID:22623647
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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Bst2
bone marrow stromal cell antigen 2
decreases expression
ISO
Azathioprine results in decreased expression of BST2 mRNA
CTD
PMID:19192274
NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
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Bub1
BUB1 mitotic checkpoint serine/threonine kinase
decreases expression
ISO
Azathioprine results in decreased expression of BUB1 mRNA
CTD
PMID:22623647
NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
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Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
decreases expression
ISO
Azathioprine results in decreased expression of BUB1B mRNA
CTD
PMID:22623647
NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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C11h3orf70
similar to human chromosome 3 open reading frame 70
decreases expression
ISO
Azathioprine results in decreased expression of C3ORF70 mRNA
CTD
PMID:22623647
NCBI chr11:79,345,857...79,396,140
Ensembl chr11:79,345,304...79,396,142
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C2h4orf46
similar to human chromosome 4 open reading frame 46
decreases expression
ISO
Azathioprine results in decreased expression of C4ORF46 mRNA
CTD
PMID:22623647
NCBI chr 2:164,762,994...164,766,126
Ensembl chr 2:164,762,960...164,766,128
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C2h5orf34
similar to human chromosome 5 open reading frame 34
decreases expression
ISO
Azathioprine results in decreased expression of C5ORF34 mRNA
CTD
PMID:22623647
NCBI chr 2:51,553,223...51,577,090
Ensembl chr 2:51,555,432...51,577,085
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C3h11orf96
similar to human chromosome 11 open reading frame 96
increases expression
ISO
Azathioprine results in increased expression of C11ORF96 mRNA
CTD
PMID:22623647
NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523
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Cadm1
cell adhesion molecule 1
decreases expression
ISO
Azathioprine results in decreased expression of CADM1 mRNA
CTD
PMID:22623647
NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
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Car2
carbonic anhydrase 2
increases expression
EXP
Azathioprine results in increased expression of CA2 mRNA
CTD
PMID:28138970
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Cavin2
caveolae associated protein 2
decreases expression
ISO
Azathioprine results in decreased expression of CAVIN2 mRNA
CTD
PMID:22623647
NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
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Ccdc138
coiled-coil domain containing 138
decreases expression
ISO
Azathioprine results in decreased expression of CCDC138 mRNA
CTD
PMID:22623647
NCBI chr20:26,493,624...26,572,367
Ensembl chr20:26,495,235...26,572,376
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Ccdc15
coiled-coil domain containing 15
decreases expression
ISO
Azathioprine results in decreased expression of CCDC15 mRNA
CTD
PMID:22623647
NCBI chr 8:36,991,147...37,068,849
Ensembl chr 8:36,998,867...37,068,919
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Ccdc18
coiled-coil domain containing 18
decreases expression
ISO
Azathioprine results in decreased expression of CCDC18 mRNA
CTD
PMID:22623647
NCBI chr14:1,501,749...1,607,672
Ensembl chr14:1,501,784...1,607,711
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Ccdc34
coiled-coil domain containing 34
decreases expression
ISO
Azathioprine results in decreased expression of CCDC34 mRNA
CTD
PMID:22623647
NCBI chr 3:96,553,074...96,588,310
Ensembl chr 3:96,552,992...96,588,146
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Ccdc77
coiled-coil domain containing 77
decreases expression
ISO
Azathioprine results in decreased expression of CCDC77 mRNA
CTD
PMID:22623647
NCBI chr 4:153,534,184...153,566,059
Ensembl chr 4:153,534,187...153,566,545
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Ccl2
C-C motif chemokine ligand 2
multiple interactions
ISO
Azathioprine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein]
CTD
PMID:36416909
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl20
C-C motif chemokine ligand 20
decreases expression
ISO
Azathioprine results in decreased expression of CCL20 mRNA; Azathioprine results in decreased expression of CCL20 protein
CTD
PMID:19192274
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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Ccl3
C-C motif chemokine ligand 3
multiple interactions
ISO
Azathioprine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein]
CTD
PMID:36416909
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccl9
C-C motif chemokine ligand 9
increases expression
ISO
Azathioprine results in increased expression of CCL15 mRNA
CTD
PMID:22623647
NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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Ccn1
cellular communication network factor 1
increases expression
ISO
Azathioprine results in increased expression of CCN1 mRNA
CTD
PMID:19192274
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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Ccna2
cyclin A2
decreases expression
ISO
Azathioprine results in decreased expression of CCNA2 mRNA
CTD
PMID:22623647
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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Ccnb1
cyclin B1
decreases expression
ISO
Azathioprine results in decreased expression of CCNB1 mRNA
CTD
PMID:22623647
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Ccne2
cyclin E2
decreases expression
ISO
Azathioprine results in decreased expression of CCNE2 mRNA
CTD
PMID:22623647
NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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Cd14
CD14 molecule
increases expression
ISO
Azathioprine results in increased expression of CD14 mRNA
CTD
PMID:22623647
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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Cd36
CD36 molecule
increases expression
EXP
Azathioprine results in increased expression of CD36 mRNA
CTD
PMID:28138970
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cdc20
cell division cycle 20
decreases expression
ISO
Azathioprine results in decreased expression of CDC20 mRNA
CTD
PMID:22623647
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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Cdc25a
cell division cycle 25A
decreases expression
ISO
Azathioprine results in decreased expression of CDC25A mRNA
CTD
PMID:22623647
NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
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Cdc25c
cell division cycle 25C
decreases expression
ISO
Azathioprine results in decreased expression of CDC25C mRNA
CTD
PMID:22623647
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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Cdc45
cell division cycle 45
decreases expression
ISO
Azathioprine results in decreased expression of CDC45 mRNA
CTD
PMID:22623647
NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
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Cdc6
cell division cycle 6
decreases expression
ISO
Azathioprine results in decreased expression of CDC6 mRNA
CTD
PMID:22623647
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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Cdc7
cell division cycle 7
decreases expression
ISO
Azathioprine results in decreased expression of CDC7 mRNA
CTD
PMID:22623647
NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
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Cdca2
cell division cycle associated 2
decreases expression
ISO
Azathioprine results in decreased expression of CDCA2 mRNA
CTD
PMID:22623647
NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
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Cdca3
cell division cycle associated 3
decreases expression
ISO
Azathioprine results in decreased expression of CDCA3 mRNA
CTD
PMID:22623647
NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
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Cdca5
cell division cycle associated 5
decreases expression
ISO
Azathioprine results in decreased expression of CDCA5 mRNA
CTD
PMID:22623647
NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
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Cdca7
cell division cycle associated 7
decreases expression
ISO
Azathioprine results in decreased expression of CDCA7 mRNA
CTD
PMID:22623647
NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
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Cdca7l
cell division cycle associated 7 like
decreases expression
ISO
Azathioprine results in decreased expression of CDCA7L mRNA
CTD
PMID:22623647
NCBI chr 6:138,793,953...138,839,889
Ensembl chr 6:138,794,228...138,839,888
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Cdca8
cell division cycle associated 8
decreases expression
ISO
Azathioprine results in decreased expression of CDCA8 mRNA
CTD
PMID:22623647
NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
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Cdk1
cyclin-dependent kinase 1
decreases expression
ISO
Azathioprine results in decreased expression of CDK1 mRNA
CTD
PMID:22623647
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
Azathioprine results in increased expression of CDKN1A mRNA; Azathioprine results in increased expression of CDKN1A protein
CTD
PMID:22623647 PMID:27358234
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn2b
cyclin-dependent kinase inhibitor 2B
increases expression
ISO
Azathioprine results in increased expression of CDKN2B mRNA
CTD
PMID:22623647
NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
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Cdkn3
cyclin-dependent kinase inhibitor 3
decreases expression
ISO
Azathioprine results in decreased expression of CDKN3 mRNA
CTD
PMID:22623647
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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Cenpa
centromere protein A
decreases expression
ISO
Azathioprine results in decreased expression of CENPA mRNA
CTD
PMID:22623647
NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
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Cenpe
centromere protein E
decreases expression
ISO
Azathioprine results in decreased expression of CENPE mRNA
CTD
PMID:22623647
NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
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Cenpf
centromere protein F
decreases expression
ISO
Azathioprine results in decreased expression of CENPF mRNA
CTD
PMID:22623647
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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Cenph
centromere protein H
decreases expression
ISO
Azathioprine results in decreased expression of CENPH mRNA
CTD
PMID:22623647
NCBI chr 2:31,896,675...31,910,179
Ensembl chr 2:31,894,667...31,910,154
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Cenpk
centromere protein K
decreases expression
ISO
Azathioprine results in decreased expression of CENPK mRNA
CTD
PMID:22623647
NCBI chr 2:35,360,390...35,421,372
Ensembl chr 2:35,360,132...35,385,706
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Cenpu
centromere protein U
decreases expression
ISO
Azathioprine results in decreased expression of CENPU mRNA
CTD
PMID:22623647
NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823
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Cep152
centrosomal protein 152
decreases expression
ISO
Azathioprine results in decreased expression of CEP152 mRNA
CTD
PMID:22623647
NCBI chr 3:112,803,185...112,878,298
Ensembl chr 3:112,810,425...112,878,458 Ensembl chr 3:112,810,425...112,878,458
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Cep192
centrosomal protein 192
decreases expression
ISO
Azathioprine results in decreased expression of CEP192 mRNA
CTD
PMID:22623647
NCBI chr18:61,373,937...61,458,405
Ensembl chr18:61,332,158...61,458,379
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Cep55
centrosomal protein 55
decreases expression
ISO
Azathioprine results in decreased expression of CEP55 mRNA
CTD
PMID:22623647
NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
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Cfi
complement factor I
decreases expression
ISO
Azathioprine results in decreased expression of CFI mRNA
CTD
PMID:22623647
NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561
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Chek1
checkpoint kinase 1
decreases expression
ISO
Azathioprine results in decreased expression of CHEK1 mRNA
CTD
PMID:22623647
NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
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Chst9
carbohydrate sulfotransferase 9
decreases expression
ISO
Azathioprine results in decreased expression of CHST9 mRNA
CTD
PMID:22623647
NCBI chr18:6,576,391...6,851,078
Ensembl chr18:6,577,348...6,850,868
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Cit
citron rho-interacting serine/threonine kinase
decreases expression
ISO
Azathioprine results in decreased expression of CIT mRNA
CTD
PMID:22623647
NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
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Ckap2
cytoskeleton associated protein 2
decreases expression
ISO
Azathioprine results in decreased expression of CKAP2 mRNA
CTD
PMID:22623647
NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
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Ckb
creatine kinase B
decreases expression
ISO
Azathioprine results in decreased expression of CKB mRNA
CTD
PMID:22623647
NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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Clgn
calmegin
decreases expression
ISO
Azathioprine results in decreased expression of CLGN mRNA
CTD
PMID:19192274
NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758
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Clip2
CAP-GLY domain containing linker protein 2
increases expression
ISO
Azathioprine results in increased expression of CLIP2 mRNA
CTD
PMID:22623647
NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023
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Col1a1
collagen type I alpha 1 chain
increases expression
ISO
Azathioprine results in increased expression of COL1A1 mRNA
CTD
PMID:19192274
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Colec12
collectin sub-family member 12
increases expression
ISO
Azathioprine results in increased expression of COLEC12 mRNA
CTD
PMID:19192274
NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618
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Cpb2
carboxypeptidase B2
decreases expression
ISO
Azathioprine results in decreased expression of CPB2 mRNA
CTD
PMID:22623647
NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
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Cpeb4
cytoplasmic polyadenylation element binding protein 4
increases expression
ISO
Azathioprine results in increased expression of CPEB4 mRNA
CTD
PMID:22623647
NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603
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Creb5
cAMP responsive element binding protein 5
increases expression
ISO
Azathioprine results in increased expression of CREB5 mRNA
CTD
PMID:22623647
NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325
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Crybg1
crystallin beta-gamma domain containing 1
decreases expression
ISO
Azathioprine results in decreased expression of CRYBG1 mRNA
CTD
PMID:22623647
NCBI chr20:47,425,030...47,496,918
Ensembl chr20:47,426,183...47,621,392
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Csf3
colony stimulating factor 3
decreases expression
ISO
Azathioprine results in decreased expression of CSF3 mRNA
CTD
PMID:19192274
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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Csta
cystatin A
increases expression
ISO
Azathioprine results in increased expression of CSTA mRNA
CTD
PMID:22623647
NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
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Ctsb
cathepsin B
increases expression
ISO
Azathioprine results in increased expression of CTSB mRNA
CTD
PMID:22623647
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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Ctsl
cathepsin L
increases expression
ISO
Azathioprine results in increased expression of CTSL mRNA
CTD
PMID:22623647
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
Azathioprine results in increased expression of CXCL2 mRNA
CTD
PMID:24184165
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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Cxcr4
C-X-C motif chemokine receptor 4
decreases expression
ISO
Azathioprine results in decreased expression of CXCR4 mRNA
CTD
PMID:19192274
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cyp2s1
cytochrome P450, family 2, subfamily s, polypeptide 1
increases expression
ISO
Azathioprine results in increased expression of CYP2S1 mRNA
CTD
PMID:22623647
NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
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Dcdc2
doublecortin domain containing 2
decreases expression
ISO
Azathioprine results in decreased expression of DCDC2 mRNA
CTD
PMID:22623647
NCBI chr17:39,845,952...40,031,781
Ensembl chr17:39,845,952...40,030,743
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Dck
deoxycytidine kinase
decreases expression
ISO
Azathioprine results in decreased expression of DCK mRNA
CTD
PMID:22623647
NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247
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Ddc
dopa decarboxylase
decreases expression
ISO
Azathioprine results in decreased expression of DDC mRNA
CTD
PMID:22623647
NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
Azathioprine results in increased expression of DDIT3 mRNA
CTD
PMID:22623647
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddx10
DEAD-box helicase 10
increases expression
ISO
Azathioprine results in increased expression of DDX10 mRNA
CTD
PMID:19192274
NCBI chr 8:53,488,656...53,643,373
Ensembl chr 8:53,488,656...53,643,373
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Depdc1
DEP domain containing 1
decreases expression
ISO
Azathioprine results in decreased expression of DEPDC1 mRNA
CTD
PMID:22623647
NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951
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Depdc1b
DEP domain containing 1B
decreases expression
ISO
Azathioprine results in decreased expression of DEPDC1B mRNA
CTD
PMID:22623647
NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779
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Diaph3
diaphanous-related formin 3
decreases expression
ISO
Azathioprine results in decreased expression of DIAPH3 mRNA
CTD
PMID:22623647
NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
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Dio1
iodothyronine deiodinase 1
decreases expression
ISO
Azathioprine results in decreased expression of DIO1 mRNA
CTD
PMID:22623647
NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
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Dkk1
dickkopf WNT signaling pathway inhibitor 1
decreases expression
ISO
Azathioprine results in decreased expression of DKK1 mRNA
CTD
PMID:22623647
NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
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Dlgap5
DLG associated protein 5
decreases expression
ISO
Azathioprine results in decreased expression of DLGAP5 mRNA
CTD
PMID:22623647
NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
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Dnmt3b
DNA methyltransferase 3 beta
decreases expression
ISO
Azathioprine results in decreased expression of DNMT3B mRNA
CTD
PMID:22623647
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
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Dpp4
dipeptidylpeptidase 4
decreases expression
ISO
Azathioprine results in decreased expression of DPP4 mRNA
CTD
PMID:12806628
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Dpyd
dihydropyrimidine dehydrogenase
decreases expression
ISO
Azathioprine results in decreased expression of DPYD mRNA
CTD
PMID:22623647
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
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Dscc1
DNA replication and sister chromatid cohesion 1
decreases expression
ISO
Azathioprine results in decreased expression of DSCC1 mRNA
CTD
PMID:22623647
NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212
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Dsn1
DSN1 component of MIS12 kinetochore complex
decreases expression
ISO
Azathioprine results in decreased expression of DSN1 mRNA
CTD
PMID:22623647
NCBI chr 3:145,652,741...145,668,025
Ensembl chr 3:145,652,737...145,665,856
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Dtl
denticleless E3 ubiquitin protein ligase homolog
decreases expression
ISO
Azathioprine results in decreased expression of DTL mRNA
CTD
PMID:22623647
NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
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Dtx4
deltex E3 ubiquitin ligase 4
decreases expression
ISO
Azathioprine results in decreased expression of DTX4 mRNA
CTD
PMID:22623647
NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818
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Dusp1
dual specificity phosphatase 1
increases expression
ISO
Azathioprine results in increased expression of DUSP1 mRNA
CTD
PMID:22623647
NCBI chr10:16,680,478...16,683,275
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Dusp5
dual specificity phosphatase 5
increases expression
ISO
Azathioprine results in increased expression of DUSP5 mRNA
CTD
PMID:22623647
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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Dzip1
DAZ interacting zinc finger protein 1
decreases expression
ISO
Azathioprine results in decreased expression of DZIP1 mRNA
CTD
PMID:22623647
NCBI chr15:95,956,329...96,009,994
Ensembl chr15:95,956,398...96,010,066
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E2f5
E2F transcription factor 5
decreases expression
ISO
Azathioprine results in decreased expression of E2F5 mRNA
CTD
PMID:22623647
NCBI chr 2:86,997,331...87,012,908
Ensembl chr 2:86,997,332...87,012,990
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E2f7
E2F transcription factor 7
decreases expression
ISO
Azathioprine results in decreased expression of E2F7 mRNA
CTD
PMID:22623647
NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734
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E2f8
E2F transcription factor 8
decreases expression
ISO
Azathioprine results in decreased expression of E2F8 mRNA
CTD
PMID:22623647
NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
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Efcab11
EF-hand calcium binding domain 11
decreases expression
ISO
Azathioprine results in decreased expression of EFCAB11 mRNA
CTD
PMID:22623647
NCBI chr 6:119,008,908...119,162,994
Ensembl chr 6:119,008,919...119,162,046
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Efemp1
EGF containing fibulin extracellular matrix protein 1
increases expression
ISO
Azathioprine results in increased expression of EFEMP1 mRNA
CTD
PMID:19192274
NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
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Egr1
early growth response 1
increases expression
ISO
Azathioprine results in increased expression of EGR1 mRNA
CTD
PMID:22623647
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Egr2
early growth response 2
increases expression
ISO
Azathioprine results in increased expression of EGR2 mRNA
CTD
PMID:22623647
NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
decreases expression
ISO
Azathioprine results in decreased expression of EHHADH mRNA
CTD
PMID:22623647
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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Eid3
EP300 interacting inhibitor of differentiation 3
increases expression
ISO
Azathioprine results in increased expression of EID3 mRNA
CTD
PMID:22623647
NCBI chr 7:20,860,073...20,861,395
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Emp3
epithelial membrane protein 3
increases expression
ISO
Azathioprine results in increased expression of EMP3 mRNA
CTD
PMID:22623647
NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
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Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
increases expression
ISO
Azathioprine results in increased expression of ENPP2 mRNA
CTD
PMID:19192274
NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
G
Enpp3
ectonucleotide pyrophosphatase/phosphodiesterase 3
decreases expression
ISO
Azathioprine results in decreased expression of ENPP3 mRNA
CTD
PMID:22623647
NCBI chr 1:20,563,700...20,635,044
Ensembl chr 1:20,563,697...20,635,041
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Entpd3
ectonucleoside triphosphate diphosphohydrolase 3
increases expression
ISO
Azathioprine results in increased expression of ENTPD3 mRNA
CTD
PMID:19192274
NCBI chr 8:120,246,412...120,277,943
Ensembl chr 8:120,247,121...120,277,943
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Epb41l2
erythrocyte membrane protein band 4.1-like 2
decreases expression
ISO
Azathioprine results in decreased expression of EPB41L2 mRNA
CTD
PMID:22623647
NCBI chr 1:19,863,010...20,037,795
Ensembl chr 1:19,863,009...20,037,721
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Ephx1
epoxide hydrolase 1
increases expression
ISO
Azathioprine results in increased expression of EPHX1 mRNA
CTD
PMID:22623647
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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Ercc1
ERCC excision repair 1, endonuclease non-catalytic subunit
increases expression
ISO
Azathioprine results in increased expression of ERCC1 mRNA
CTD
PMID:22623647
NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
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Erp27
endoplasmic reticulum protein 27
decreases expression
ISO
Azathioprine results in decreased expression of ERP27 mRNA
CTD
PMID:22623647
NCBI chr 4:169,804,656...169,821,660
Ensembl chr 4:169,804,658...169,821,660
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Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
decreases expression
ISO
Azathioprine results in decreased expression of ESCO2 mRNA
CTD
PMID:22623647
NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
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Espl1
extra spindle pole bodies like 1, separase
decreases expression
ISO
Azathioprine results in decreased expression of ESPL1 mRNA
CTD
PMID:22623647
NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
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Exo1
exonuclease 1
decreases expression
ISO
Azathioprine results in decreased expression of EXO1 mRNA
CTD
PMID:22623647
NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
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Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
decreases expression
ISO
Azathioprine results in decreased expression of EZH2 mRNA
CTD
PMID:22623647
NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
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Fabp1
fatty acid binding protein 1
decreases expression
ISO
Azathioprine results in decreased expression of FABP1 mRNA
CTD
PMID:22623647
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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Fam161a
FAM161 centrosomal protein A
decreases expression
ISO
Azathioprine results in decreased expression of FAM161A mRNA
CTD
PMID:22623647
NCBI chr14:97,009,449...97,027,865
Ensembl chr14:97,009,491...97,028,588
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Fam3b
FAM3 metabolism regulating signaling molecule B
decreases expression
ISO
Azathioprine results in decreased expression of FAM3B mRNA
CTD
PMID:22623647
NCBI chr11:36,831,532...36,863,902
Ensembl chr11:36,831,532...36,869,713
G
Fam43a
family with sequence similarity 43, member A
increases expression
ISO
Azathioprine results in increased expression of FAM43A mRNA
CTD
PMID:22623647
NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401
G
Fam83d
family with sequence similarity 83, member D
decreases expression
ISO
Azathioprine results in decreased expression of FAM83D mRNA
CTD
PMID:22623647
NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
G
Fanci
FA complementation group I
decreases expression
ISO
Azathioprine results in decreased expression of FANCI mRNA
CTD
PMID:22623647
NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
G
Fbln1
fibulin 1
increases expression
ISO
Azathioprine results in increased expression of FBLN1 mRNA
CTD
PMID:19192274
NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
G
Fbxo30
F-box protein 30
increases expression
ISO
Azathioprine results in increased expression of FBXO30 mRNA
CTD
PMID:26198647
NCBI chr 1:5,655,341...5,671,558
Ensembl chr 1:5,655,339...5,672,441
G
Fbxo5
F-box protein 5
decreases expression
ISO
Azathioprine results in decreased expression of FBXO5 mRNA
CTD
PMID:22623647
NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
G
Fen1
flap structure-specific endonuclease 1
decreases expression
ISO
Azathioprine results in decreased expression of FEN1 mRNA
CTD
PMID:22623647
NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
G
Fga
fibrinogen alpha chain
decreases expression
ISO
Azathioprine results in decreased expression of FGA mRNA
CTD
PMID:22623647
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
G
Fgf7
fibroblast growth factor 7
increases expression
ISO
Azathioprine results in increased expression of FGF7 mRNA
CTD
PMID:19192274
NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
G
Fhl3
four and a half LIM domains 3
increases expression
ISO
Azathioprine results in increased expression of FHL3 mRNA
CTD
PMID:22623647
NCBI chr 5:136,953,947...136,961,317
Ensembl chr 5:136,950,411...136,961,317
G
Firrm
FIGNL1 interacting regulator of recombination and mitosis
decreases expression
ISO
Azathioprine results in decreased expression of FIRRM mRNA
CTD
PMID:22623647
NCBI chr13:76,301,914...76,345,842
Ensembl chr13:76,301,918...76,345,804
G
Fmo2
flavin containing dimethylaniline monoxygenase 2
increases expression
ISO
Azathioprine results in increased expression of FMO2 mRNA
CTD
PMID:21621594
NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
G
Fmo5
flavin containing dimethylaniline monoxygenase 5
decreases expression
ISO
Azathioprine results in decreased expression of FMO5 mRNA
CTD
PMID:22623647
NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Azathioprine results in increased expression of FOS mRNA
CTD
PMID:22623647 PMID:23958494
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Fosl1
FOS like 1, AP-1 transcription factor subunit
increases expression
ISO
Azathioprine results in increased expression of FOSL1 mRNA
CTD
PMID:22623647
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
G
Foxa1
forkhead box A1
decreases expression
ISO
Azathioprine results in decreased expression of FOXA1 mRNA
CTD
PMID:22623647
NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
G
Foxm1
forkhead box M1
decreases expression
ISO
Azathioprine results in decreased expression of FOXM1 mRNA
CTD
PMID:22623647
NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
G
Foxo1
forkhead box O1
multiple interactions
ISO
Azathioprine inhibits the reaction [IGF1 protein results in increased phosphorylation of FOXO1 protein]
CTD
PMID:23958494
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
G
Fsaf1
40S small subunit processome assembly factor 1
decreases expression
ISO
Azathioprine results in decreased expression of FSAF1 mRNA
CTD
PMID:22623647
NCBI chr19:52,807,932...52,822,259
Ensembl chr19:52,807,934...52,822,267
G
Fst
follistatin
increases expression
ISO
Azathioprine results in increased expression of FST mRNA
CTD
PMID:22623647
NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
G
Gabre
gamma-aminobutyric acid type A receptor subunit epsilon
increases expression
ISO
Azathioprine results in increased expression of GABRE mRNA
CTD
PMID:22623647
NCBI chr X:150,060,035...150,078,773
Ensembl chr X:150,060,040...150,078,693
G
Gadd45b
growth arrest and DNA-damage-inducible, beta
increases expression
ISO
Azathioprine results in increased expression of GADD45B mRNA
CTD
PMID:22623647
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
G
Gas2l3
growth arrest-specific 2 like 3
decreases expression
ISO
Azathioprine results in decreased expression of GAS2L3 mRNA
CTD
PMID:22623647
NCBI chr 7:23,803,578...23,836,816
Ensembl chr 7:23,806,310...23,836,411
G
Gbp1
guanylate binding protein 1
decreases expression
ISO
Azathioprine results in decreased expression of GBP1 mRNA
CTD
PMID:19192274
NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131 Ensembl chr 2:231,398,163...231,432,131
G
Gca
grancalcin
decreases expression
ISO
Azathioprine results in decreased expression of GCA mRNA
CTD
PMID:22623647
NCBI chr 3:47,297,320...47,329,913
Ensembl chr 3:47,297,383...47,328,581
G
Gckr
glucokinase regulator
increases expression
ISO
Azathioprine results in increased expression of GCKR mRNA
CTD
PMID:22623647
NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO
Azathioprine results in increased expression of GCLC mRNA
CTD
PMID:22623647 PMID:26198647
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
Azathioprine results in increased expression of GCLM mRNA
CTD
PMID:18222062 PMID:22623647 PMID:26198647
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gcnt3
glucosaminyl (N-acetyl) transferase 3, mucin type
increases expression
ISO
Azathioprine results in increased expression of GCNT3 mRNA
CTD
PMID:22623647 PMID:26198647
NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
G
Gdf15
growth differentiation factor 15
increases expression
ISO
Azathioprine results in increased expression of GDF15 mRNA
CTD
PMID:22623647
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
G
Gdpd5
glycerophosphodiester phosphodiesterase domain containing 5
decreases expression
ISO
Azathioprine results in decreased expression of GDPD5 mRNA
CTD
PMID:22623647
NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446
G
Ggh
gamma-glutamyl hydrolase
decreases expression
ISO
Azathioprine results in decreased expression of GGH mRNA
CTD
PMID:22623647
NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
G
Gins1
GINS complex subunit 1
decreases expression
ISO
Azathioprine results in decreased expression of GINS1 mRNA
CTD
PMID:22623647
NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936
G
Gins2
GINS complex subunit 2
decreases expression
ISO
Azathioprine results in decreased expression of GINS2 mRNA
CTD
PMID:22623647
NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
G
Gins3
GINS complex subunit 3
decreases expression
ISO
Azathioprine results in decreased expression of GINS3 mRNA
CTD
PMID:22623647
NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687
G
Gipc2
GIPC PDZ domain containing family, member 2
decreases expression
ISO
Azathioprine results in decreased expression of GIPC2 mRNA
CTD
PMID:22623647
NCBI chr 2:241,030,764...241,110,236
Ensembl chr 2:241,030,770...241,110,236
G
Glrx
glutaredoxin
increases expression
ISO
Azathioprine results in increased expression of GLRX mRNA
CTD
PMID:22623647
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
G
Glud1
glutamate dehydrogenase 1
decreases expression
ISO
Azathioprine results in decreased expression of GLUD1 mRNA
CTD
PMID:22623647
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Gmnn
geminin, DNA replication inhibitor
decreases expression
ISO
Azathioprine results in decreased expression of GMNN mRNA
CTD
PMID:22623647
NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
G
Golm1
golgi membrane protein 1
increases expression
ISO
Azathioprine results in increased expression of GOLM1 mRNA
CTD
PMID:22623647
NCBI chr17:4,995,925...5,044,329
Ensembl chr17:4,996,104...5,034,057
G
Golt1a
golgi transport 1A
increases expression
ISO
Azathioprine results in increased expression of GOLT1A mRNA
CTD
PMID:22623647
NCBI chr13:44,760,356...44,773,123
Ensembl chr13:44,760,380...44,773,122
G
Gpat3
glycerol-3-phosphate acyltransferase 3
increases expression
ISO
Azathioprine results in increased expression of GPAT3 mRNA
CTD
PMID:26198647
NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
G
Gpm6b
glycoprotein m6b
increases expression
ISO
Azathioprine results in increased expression of GPM6B mRNA
CTD
PMID:19192274
NCBI chr X:28,057,788...28,204,409
Ensembl chr X:28,059,450...28,204,211
G
Gpr137b
G protein-coupled receptor 137B
increases expression
ISO
Azathioprine results in increased expression of GPR137B mRNA
CTD
PMID:22623647
NCBI chr17:86,003,635...86,041,841
Ensembl chr17:85,966,921...86,041,835
G
Gpt
glutamic--pyruvic transaminase
increases expression multiple interactions
ISO
Azathioprine results in increased expression of GPT protein eritoran inhibits the reaction [Azathioprine results in increased expression of GPT protein]
CTD
PMID:24184165
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Gpx2
glutathione peroxidase 2
increases expression
ISO
Azathioprine results in increased expression of GPX2 mRNA
CTD
PMID:18222062
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
G
Gpx3
glutathione peroxidase 3
increases expression
ISO
Azathioprine results in increased expression of GPX3 mRNA
CTD
PMID:18222062
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
G
Grb10
growth factor receptor bound protein 10
increases expression
ISO
Azathioprine results in increased expression of GRB10 mRNA
CTD
PMID:22623647
NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806
G
Grb14
growth factor receptor bound protein 14
decreases expression
ISO
Azathioprine results in decreased expression of GRB14 mRNA
CTD
PMID:22623647
NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
G
Gsdme
gasdermin E
decreases expression
ISO
Azathioprine results in decreased expression of GSDME mRNA
CTD
PMID:19192274
NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806
G
Gsr
glutathione-disulfide reductase
increases expression
ISO
Azathioprine results in increased expression of GSR mRNA
CTD
PMID:26198647
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gss
glutathione synthetase
increases expression
ISO
Azathioprine results in increased expression of GSS mRNA
CTD
PMID:18222062
NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
G
Gsta1
glutathione S-transferase alpha 1
affects metabolic processing
ISO
GSTA1 protein affects the metabolism of Azathioprine
CTD
PMID:18155239
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
G
Gsta2
glutathione S-transferase alpha 2
affects response to substance affects metabolic processing
ISO
GSTA2 gene polymorphism affects the susceptibility to Azathioprine GSTA2 protein affects the metabolism of Azathioprine
CTD
PMID:18155239 PMID:20434437
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
G
Gstm1
glutathione S-transferase mu 1
affects metabolic processing affects response to substance
ISO
GSTM1 protein affects the metabolism of Azathioprine GSTM1 gene polymorphism affects the susceptibility to Azathioprine
CTD
PMID:17206640 PMID:18155239 PMID:20434437
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
G
Gtse1
G-2 and S-phase expressed 1
decreases expression
ISO
Azathioprine results in decreased expression of GTSE1 mRNA
CTD
PMID:22623647
NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
G
H2ax
H2A.X variant histone
decreases expression
ISO
Azathioprine results in decreased expression of H2AX mRNA
CTD
PMID:22623647
NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
G
H2az1
H2A.Z variant histone 1
decreases expression
ISO
Azathioprine results in decreased expression of H2AZ1 mRNA
CTD
PMID:22623647
NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485
G
H2az2
H2A.Z variant histone 2
decreases expression
ISO
Azathioprine results in decreased expression of H2AZ2 mRNA
CTD
PMID:22623647
NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144 Ensembl chr 4:81,293,299...81,312,144 Ensembl chr16:81,293,299...81,312,144
G
Hadh
hydroxyacyl-CoA dehydrogenase
decreases expression
ISO
Azathioprine results in decreased expression of HADH mRNA
CTD
PMID:22623647
NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
G
Haus6
HAUS augmin like complex subunit 6
decreases expression
ISO
Azathioprine results in decreased expression of HAUS6 mRNA
CTD
PMID:22623647
NCBI chr 5:101,116,532...101,156,396
Ensembl chr 5:101,119,300...101,153,124
G
Hells
helicase, lymphoid specific
decreases expression
ISO
Azathioprine results in decreased expression of HELLS mRNA
CTD
PMID:22623647
NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
G
Herc6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
decreases expression
ISO
Azathioprine results in decreased expression of HERC6 mRNA
CTD
PMID:19192274
NCBI chr 4:87,524,470...87,566,895
Ensembl chr 4:87,524,493...87,581,744
G
Hey1
hes-related family bHLH transcription factor with YRPW motif 1
increases expression
ISO
Azathioprine results in increased expression of HEY1 mRNA
CTD
PMID:22623647
NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
G
Hhex
hematopoietically expressed homeobox
decreases expression
ISO
Azathioprine results in decreased expression of HHEX mRNA
CTD
PMID:22623647
NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
G
Hhipl2
HHIP like 2
increases expression
ISO
Azathioprine results in increased expression of HHIPL2 mRNA
CTD
PMID:22623647
NCBI chr13:95,054,685...95,074,609
Ensembl chr13:95,054,694...95,074,608
G
Hilpda
hypoxia inducible lipid droplet-associated
decreases expression
ISO
Azathioprine results in decreased expression of HILPDA mRNA
CTD
PMID:19192274
NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
G
Hist1h2bc
histone cluster 1, H2bc
increases expression
ISO
Azathioprine results in increased expression of H2BC21 mRNA
CTD
PMID:22623647
NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642
G
Hist1h2bd
histone cluster 1 H2B family member D
increases expression
ISO
Azathioprine results in increased expression of H2BC5 mRNA
CTD
PMID:22623647
NCBI chr17:42,792,887...42,793,268
G
Hk1
hexokinase 1
increases expression
ISO
Azathioprine results in increased expression of HK1 mRNA
CTD
PMID:22623647
NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
G
Hk2
hexokinase 2
decreases expression
ISO
Azathioprine results in decreased expression of HK2 mRNA
CTD
PMID:22623647
NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
G
Hmgb1
high mobility group box 1
increases expression
ISO
Azathioprine results in increased expression of HMGB1 protein
CTD
PMID:24184165
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
G
Hmgb2
high mobility group box 2
decreases expression
ISO
Azathioprine results in decreased expression of HMGB2 mRNA
CTD
PMID:22623647
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 Ensembl chr 1:32,710,658...32,713,140
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
decreases expression
ISO
Azathioprine results in decreased expression of HMGCR mRNA
CTD
PMID:22623647
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
G
Hmgn3
high mobility group nucleosomal binding domain 3
decreases expression
ISO
Azathioprine results in decreased expression of HMGN3 mRNA
CTD
PMID:22623647
NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976
G
Hmmr
hyaluronan-mediated motility receptor
decreases expression
ISO
Azathioprine results in decreased expression of HMMR mRNA
CTD
PMID:22623647
NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
G
Hoxd1
homeo box D1
decreases expression
ISO
Azathioprine results in decreased expression of HOXD1 mRNA
CTD
PMID:22623647
NCBI chr 3:59,665,629...59,667,769
Ensembl chr 3:59,665,629...59,667,769
G
Hp
haptoglobin
multiple interactions
EXP
[Carbon Tetrachloride co-treated with Azathioprine] results in increased expression of HP protein
CTD
PMID:8614026
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
increases mutagenesis
ISO
Azathioprine results in increased mutagenesis of HPRT1 gene
CTD
PMID:16107271
NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
G
Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
decreases expression
ISO
Azathioprine results in decreased expression of HSD11B1 mRNA
CTD
PMID:19192274
NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
G
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
decreases expression
ISO
Azathioprine results in decreased expression of HSD11B2 mRNA
CTD
PMID:22623647
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
G
Hsdl2
hydroxysteroid dehydrogenase like 2
decreases expression
ISO
Azathioprine results in decreased expression of HSDL2 mRNA
CTD
PMID:22623647
NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
G
Hsf1
heat shock transcription factor 1
increases activity
ISO
Azathioprine results in increased activity of HSF1 protein
CTD
PMID:34170685
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
G
Id3
inhibitor of DNA binding 3
increases expression
ISO
Azathioprine results in increased expression of ID3 mRNA
CTD
PMID:19192274
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
G
Idh1
isocitrate dehydrogenase (NADP(+)) 1
decreases expression
ISO
Azathioprine results in decreased expression of IDH1 mRNA
CTD
PMID:22623647
NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
G
Idi1
isopentenyl-diphosphate delta isomerase 1
decreases expression
ISO
Azathioprine results in decreased expression of IDI1 mRNA
CTD
PMID:22623647
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
G
Ier2
immediate early response 2
increases expression
ISO
Azathioprine results in increased expression of IER2 mRNA
CTD
PMID:22623647
NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
G
Ier3
immediate early response 3
increases expression
ISO
Azathioprine results in increased expression of IER3 mRNA
CTD
PMID:22623647
NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
G
Ier5
immediate early response 5
increases expression
ISO
Azathioprine results in increased expression of IER5 mRNA
CTD
PMID:22623647
NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
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Ier5l
immediate early response 5-like
increases expression
ISO
Azathioprine results in increased expression of IER5L mRNA
CTD
PMID:22623647
NCBI chr 3:13,744,056...13,745,647
Ensembl chr 3:13,744,078...13,745,647
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Ifi27
interferon, alpha-inducible protein 27
decreases expression
ISO
Azathioprine results in decreased expression of IFI27 mRNA
CTD
PMID:19192274
NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
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Ifi35
interferon-induced protein 35
decreases expression
ISO
Azathioprine results in decreased expression of IFI35 mRNA
CTD
PMID:19192274
NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952
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Ifi44
interferon-induced protein 44
decreases expression
ISO
Azathioprine results in decreased expression of IFI44 mRNA
CTD
PMID:19192274
NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
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Ifi44l
interferon-induced protein 44-like
decreases expression
ISO
Azathioprine results in decreased expression of IFI44L mRNA
CTD
PMID:19192274
NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
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Ifih1
interferon induced with helicase C domain 1
decreases expression
ISO
Azathioprine results in decreased expression of IFIH1 mRNA
CTD
PMID:19192274 PMID:22623647
NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
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Ifit3
interferon-induced protein with tetratricopeptide repeats 3
decreases expression
ISO
Azathioprine results in decreased expression of IFIT3 mRNA
CTD
PMID:19192274
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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Ifnb1
interferon beta 1
decreases expression
ISO
Azathioprine results in decreased expression of IFNB1 mRNA
CTD
PMID:16473374
NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
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Ifng
interferon gamma
multiple interactions
ISO
[Azathioprine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA
CTD
PMID:29594315
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Igdcc3
immunoglobulin superfamily, DCC subclass, member 3
decreases expression
ISO
Azathioprine results in decreased expression of IGDCC3 mRNA
CTD
PMID:22623647
NCBI chr 8:65,661,165...65,707,961
Ensembl chr 8:65,661,196...65,707,959
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Igf1
insulin-like growth factor 1
multiple interactions
ISO
Azathioprine inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]; Azathioprine inhibits the reaction [IGF1 protein results in increased phosphorylation of FOXO1 protein]; Azathioprine inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein]
CTD
PMID:23958494
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igf1r
insulin-like growth factor 1 receptor
decreases expression multiple interactions
ISO
Azathioprine results in decreased expression of IGF1R protein Azathioprine inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein]
CTD
PMID:23958494
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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Igfbp3
insulin-like growth factor binding protein 3
increases expression
ISO
Azathioprine results in increased expression of IGFBP3 mRNA
CTD
PMID:22623647
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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Il11
interleukin 11
increases expression
ISO
Azathioprine results in increased expression of IL11 mRNA
CTD
PMID:22623647
NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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Il12a
interleukin 12A
multiple interactions
ISO
Azathioprine results in increased expression of [IL12A protein binds to IL12B protein]
CTD
PMID:19584951
NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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Il12b
interleukin 12B
multiple interactions
ISO
Azathioprine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]; Azathioprine results in increased expression of [IL12A protein binds to IL12B protein]
CTD
PMID:19584951 PMID:36416909
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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Il1a
interleukin 1 alpha
multiple interactions
ISO
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Azathioprine
CTD
PMID:19362101
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
increases expression
ISO
Azathioprine results in increased expression of IL1B mRNA
CTD
PMID:24184165 PMID:29594315
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il1rn
interleukin 1 receptor antagonist
decreases expression
ISO
Azathioprine results in decreased expression of IL1RN mRNA
CTD
PMID:19192274
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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Il23a
interleukin 23 subunit alpha
decreases expression
ISO
Azathioprine results in decreased expression of IL23A mRNA
CTD
PMID:19192274
NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
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Il4
interleukin 4
decreases expression
ISO
Azathioprine results in decreased expression of IL4 protein
CTD
PMID:19584951
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il6
interleukin 6
multiple interactions decreases expression
ISO
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Azathioprine Azathioprine results in decreased expression of IL6 mRNA; Azathioprine results in decreased expression of IL6 protein
CTD
PMID:19192274 PMID:19362101
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Il6r
interleukin 6 receptor
increases expression
ISO
Azathioprine results in increased expression of IL6R mRNA
CTD
PMID:22623647
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
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Il7
interleukin 7
decreases expression
ISO
Azathioprine results in decreased expression of IL7 mRNA
CTD
PMID:22623647
NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
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Impa2
inositol monophosphatase 2
decreases expression
ISO
Azathioprine results in decreased expression of IMPA2 mRNA
CTD
PMID:22623647
NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641
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Impdh1
inosine monophosphate dehydrogenase 1
affects response to substance
ISO
IMPDH1 promoter mutant form affects the susceptibility to Azathioprine
CTD
PMID:17001353
NCBI chr 4:57,801,842...57,817,434
Ensembl chr 4:57,801,831...57,819,076
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Impdh2
inosine monophosphate dehydrogenase 2
increases expression
ISO
Azathioprine results in increased expression of IMPDH2 mRNA
CTD
PMID:18222062
NCBI chr 8:109,256,705...109,261,365
Ensembl chr 8:109,256,728...109,261,359
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Irak1bp1
interleukin-1 receptor-associated kinase 1 binding protein 1
decreases expression
ISO
Azathioprine results in decreased expression of IRAK1BP1 mRNA
CTD
PMID:22623647
NCBI chr 8:83,731,512...83,748,289
Ensembl chr 8:83,731,507...83,748,289
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Irf1
interferon regulatory factor 1
decreases expression
ISO
Azathioprine results in decreased expression of IRF1 mRNA
CTD
PMID:16473374
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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Irf7
interferon regulatory factor 7
decreases expression
ISO
Azathioprine results in decreased expression of IRF7 mRNA
CTD
PMID:19192274
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
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Irs1
insulin receptor substrate 1
multiple interactions
ISO
Azathioprine results in increased phosphorylation of and results in decreased expression of IRS1 protein
CTD
PMID:23958494
NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
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Irx3
iroquois homeobox 3
decreases expression
ISO
Azathioprine results in decreased expression of IRX3 mRNA
CTD
PMID:22623647
NCBI chr19:15,211,882...15,215,317
Ensembl chr19:15,211,878...15,215,317
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Isg15
ISG15 ubiquitin-like modifier
decreases expression
ISO
Azathioprine results in decreased expression of ISG15 mRNA
CTD
PMID:19192274
NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
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Isg20
interferon stimulated exonuclease gene 20
decreases expression
ISO
Azathioprine results in decreased expression of ISG20 mRNA
CTD
PMID:19192274
NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
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Itpa
inosine triphosphatase
affects response to substance
ISO
ITPA gene polymorphism affects the susceptibility to Azathioprine; ITPA protein affects the susceptibility to Azathioprine
CTD
PMID:15167706 PMID:15571265 PMID:16431304 PMID:19129747 PMID:19214663 PMID:21544018 PMID:21961091 More...
NCBI chr 3:117,885,464...117,897,247
Ensembl chr 3:117,885,099...117,897,249
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Itprip
inositol 1,4,5-trisphosphate receptor interacting protein
increases expression
ISO
Azathioprine results in increased expression of ITPRIP mRNA
CTD
PMID:22623647
NCBI chr 1:246,762,804...246,786,379
Ensembl chr 1:246,762,472...246,786,408
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Jag1
jagged canonical Notch ligand 1
increases expression
ISO
Azathioprine results in increased expression of JAG1 mRNA
CTD
PMID:22623647
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Azathioprine results in increased expression of JUN mRNA
CTD
PMID:22623647 PMID:23958494
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Kank4
KN motif and ankyrin repeat domains 4
decreases expression
ISO
Azathioprine results in decreased expression of KANK4 mRNA
CTD
PMID:22623647
NCBI chr 5:113,401,491...113,465,526
Ensembl chr 5:113,402,468...113,465,555
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Kbtbd7
kelch repeat and BTB domain containing 7
decreases expression
ISO
Azathioprine results in decreased expression of KBTBD7 mRNA
CTD
PMID:22623647
NCBI chr15:54,806,878...54,811,457
Ensembl chr15:54,806,873...54,811,687
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Kctd3
potassium channel tetramerization domain containing 3
decreases expression
ISO
Azathioprine results in decreased expression of KCTD3 mRNA
CTD
PMID:22623647
NCBI chr13:100,510,193...100,548,765
Ensembl chr13:100,510,195...100,548,718
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Keap1
Kelch-like ECH-associated protein 1
affects response to substance
ISO
KEAP1 protein affects the susceptibility to Azathioprine
CTD
PMID:21803983
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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Kif11
kinesin family member 11
decreases expression
ISO
Azathioprine results in decreased expression of KIF11 mRNA
CTD
PMID:22623647
NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
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Kif15
kinesin family member 15
decreases expression
ISO
Azathioprine results in decreased expression of KIF15 mRNA
CTD
PMID:22623647
NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
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Kif18a
kinesin family member 18A
decreases expression
ISO
Azathioprine results in decreased expression of KIF18A mRNA
CTD
PMID:22623647
NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582
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Kif20a
kinesin family member 20A
decreases expression
ISO
Azathioprine results in decreased expression of KIF20A mRNA
CTD
PMID:22623647
NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
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Kif20b
kinesin family member 20B
decreases expression
ISO
Azathioprine results in decreased expression of KIF20B mRNA
CTD
PMID:22623647
NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
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Kif23
kinesin family member 23
decreases expression
ISO
Azathioprine results in decreased expression of KIF23 mRNA
CTD
PMID:22623647
NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
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Kif2c
kinesin family member 2C
decreases expression
ISO
Azathioprine results in decreased expression of KIF2C mRNA
CTD
PMID:22623647
NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
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Klf5
KLF transcription factor 5
increases expression
ISO
Azathioprine results in increased expression of KLF5 mRNA
CTD
PMID:22623647
NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
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Klf6
KLF transcription factor 6
increases expression
ISO
Azathioprine results in increased expression of KLF6 mRNA
CTD
PMID:22623647
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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Klhl14
kelch-like family member 14
decreases expression
ISO
Azathioprine results in decreased expression of KLHL14 mRNA
CTD
PMID:22623647
NCBI chr18:12,804,253...12,917,828
Ensembl chr18:12,804,253...12,917,828
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Kntc1
kinetochore associated 1
decreases expression
ISO
Azathioprine results in decreased expression of KNTC1 mRNA
CTD
PMID:22623647
NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561
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Kynu
kynureninase
increases expression
ISO
Azathioprine results in increased expression of KYNU mRNA
CTD
PMID:22623647
NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
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Lamb3
laminin subunit beta 3
decreases expression
ISO
Azathioprine results in decreased expression of LAMB3 mRNA
CTD
PMID:19192274
NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
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Leap2
liver enriched antimicrobial peptide 2
decreases expression
ISO
Azathioprine results in decreased expression of LEAP2 mRNA
CTD
PMID:22623647
NCBI chr10:37,580,172...37,581,244
Ensembl chr10:37,577,855...37,581,244
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Lias
lipoic acid synthetase
increases expression
ISO
Azathioprine results in increased expression of LIAS mRNA
CTD
PMID:21621594
NCBI chr14:42,876,699...42,893,824
Ensembl chr14:42,876,699...42,893,783
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Lif
LIF, interleukin 6 family cytokine
increases expression
ISO
Azathioprine results in increased expression of LIF mRNA
CTD
PMID:22623647 PMID:26198647
NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
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Lmnb1
lamin B1
decreases expression
ISO
Azathioprine results in decreased expression of LMNB1 mRNA
CTD
PMID:22623647
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
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Lpar6
lysophosphatidic acid receptor 6
decreases expression
ISO
Azathioprine results in decreased expression of LPAR6 mRNA
CTD
PMID:22623647
NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331
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Lrp10
LDL receptor related protein 10
increases expression
ISO
Azathioprine results in increased expression of LRP10 mRNA
CTD
PMID:22623647
NCBI chr15:27,921,335...27,927,507
Ensembl chr15:27,920,259...27,927,505
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Lrr1
leucine rich repeat protein 1
decreases expression
ISO
Azathioprine results in decreased expression of LRR1 mRNA
CTD
PMID:22623647
NCBI chr 6:87,643,195...87,651,894
Ensembl chr 6:87,643,217...87,651,894
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Lrrc8a
leucine rich repeat containing 8 VRAC subunit A
increases expression
ISO
Azathioprine results in increased expression of LRRC8A mRNA
CTD
PMID:22623647
NCBI chr 3:13,509,577...13,537,174
Ensembl chr 3:13,510,513...13,536,202
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Ltf
lactotransferrin
decreases expression
ISO
Azathioprine results in decreased expression of LTF mRNA
CTD
PMID:21621594
NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
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Lurap1l
leucine rich adaptor protein 1-like
increases expression
ISO
Azathioprine results in increased expression of LURAP1L mRNA
CTD
PMID:22623647
NCBI chr 5:95,362,005...95,409,439
Ensembl chr 5:95,362,005...95,409,438
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Lxn
latexin
increases expression
ISO
Azathioprine results in increased expression of LXN mRNA
CTD
PMID:19192274
NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460
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Ly6e
lymphocyte antigen 6 family member E
decreases expression
ISO
Azathioprine results in decreased expression of LY6E mRNA
CTD
PMID:19192274
NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
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Ly96
lymphocyte antigen 96
increases expression
ISO
Azathioprine results in increased expression of LY96 mRNA
CTD
PMID:22623647
NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
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Lyz2
lysozyme 2
decreases expression
ISO
Azathioprine results in decreased expression of LYZ mRNA
CTD
PMID:22623647
NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
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Mad2l1
mitotic arrest deficient 2 like 1
decreases expression
ISO
Azathioprine results in decreased expression of MAD2L1 mRNA
CTD
PMID:22623647
NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
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Maff
MAF bZIP transcription factor F
increases expression
ISO
Azathioprine results in increased expression of MAFF mRNA
CTD
PMID:22623647
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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Maged1
MAGE family member D1
decreases expression
ISO
Azathioprine results in decreased expression of MAGED1 mRNA
CTD
PMID:22623647
NCBI chr X:59,422,715...59,429,381
Ensembl chr X:59,422,717...59,429,364
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Mal2
mal, T-cell differentiation protein 2
decreases expression
ISO
Azathioprine results in decreased expression of MAL2 mRNA
CTD
PMID:22623647
NCBI chr 7:85,900,453...85,933,433
Ensembl chr 7:85,900,453...85,933,429
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Map1b
microtubule-associated protein 1B
increases expression
ISO
Azathioprine results in increased expression of MAP1B mRNA
CTD
PMID:22623647
NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
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Map2k1
mitogen activated protein kinase kinase 1
decreases phosphorylation
ISO
Azathioprine results in decreased phosphorylation of MAP2K1 protein
CTD
PMID:12697733
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
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Map2k6
mitogen-activated protein kinase kinase 6
decreases expression
ISO
Azathioprine results in decreased expression of MAP2K6 mRNA
CTD
PMID:22623647
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
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Mapk1
mitogen activated protein kinase 1
multiple interactions increases phosphorylation
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Azathioprine promotes the reaction [MAPK1 protein binds to TSC2 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Azathioprine results in increased phosphorylation of MAPK1 protein]; Azathioprine promotes the reaction [MAPK1 protein binds to TSC2 protein]
CTD
PMID:23958494
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk13
mitogen activated protein kinase 13
increases expression
ISO
Azathioprine results in increased expression of MAPK13 mRNA
CTD
PMID:22623647
NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222
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Mapk3
mitogen activated protein kinase 3
multiple interactions increases phosphorylation
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Azathioprine promotes the reaction [MAPK3 protein binds to TSC2 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Azathioprine results in increased phosphorylation of MAPK3 protein]; Azathioprine promotes the reaction [MAPK3 protein binds to TSC2 protein]
CTD
PMID:23958494
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Marcks
myristoylated alanine rich protein kinase C substrate
decreases expression
ISO
Azathioprine results in decreased expression of MARCKS mRNA
CTD
PMID:19192274
NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
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Mastl
microtubule associated serine/threonine kinase-like
decreases expression
ISO
Azathioprine results in decreased expression of MASTL mRNA
CTD
PMID:22623647
NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353
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Matn3
matrilin 3
decreases expression
ISO
Azathioprine results in decreased expression of MATN3 mRNA
CTD
PMID:22623647
NCBI chr 6:31,748,517...31,768,564
Ensembl chr 6:31,748,474...31,768,101
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Mbl2
mannose binding lectin 2
decreases expression
ISO
Azathioprine results in decreased expression of MBL2 mRNA
CTD
PMID:22623647
NCBI chr 1:228,016,439...228,024,736
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Mcm10
minichromosome maintenance 10 replication initiation factor
decreases expression
ISO
Azathioprine results in decreased expression of MCM10 mRNA
CTD
PMID:22623647
NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364
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Mcm2
minichromosome maintenance complex component 2
decreases expression
ISO
Azathioprine results in decreased expression of MCM2 mRNA
CTD
PMID:22623647
NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
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Mcm3
minichromosome maintenance complex component 3
decreases expression
ISO
Azathioprine results in decreased expression of MCM3 mRNA
CTD
PMID:22623647
NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
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Mcm4
minichromosome maintenance complex component 4
decreases expression
ISO
Azathioprine results in decreased expression of MCM4 mRNA
CTD
PMID:22623647
NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
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Mcm5
minichromosome maintenance complex component 5
decreases expression
ISO
Azathioprine results in decreased expression of MCM5 mRNA
CTD
PMID:22623647
NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
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Mcm6
minichromosome maintenance complex component 6
decreases expression
ISO
Azathioprine results in decreased expression of MCM6 mRNA
CTD
PMID:22623647
NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
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Mdm1
Mdm1 nuclear protein
decreases expression
ISO
Azathioprine results in decreased expression of MDM1 mRNA
CTD
PMID:22623647
NCBI chr 7:53,729,603...53,766,034
Ensembl chr 7:53,729,610...53,766,034
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Melk
maternal embryonic leucine zipper kinase
decreases expression
ISO
Azathioprine results in decreased expression of MELK mRNA
CTD
PMID:22623647
NCBI chr 5:58,540,393...58,600,562
Ensembl chr 5:58,540,449...58,600,937
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Met
MET proto-oncogene, receptor tyrosine kinase
decreases expression
ISO
Azathioprine results in decreased expression of MET mRNA
CTD
PMID:19192274
NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
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Metrnl
meteorin-like, glial cell differentiation regulator
increases expression
ISO
Azathioprine results in increased expression of METRNL mRNA
CTD
PMID:22623647
NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869
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Mis18a
MIS18 kinetochore protein A
decreases expression
ISO
Azathioprine results in decreased expression of MIS18A mRNA
CTD
PMID:22623647
NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062
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Mis18bp1
MIS18 binding protein 1
decreases expression
ISO
Azathioprine results in decreased expression of MIS18BP1 mRNA
CTD
PMID:22623647
NCBI chr 6:83,182,497...83,231,978
Ensembl chr 6:83,182,499...83,231,383
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Mixl1
Mix paired-like homeobox 1
decreases expression
ISO
Azathioprine results in decreased expression of MIXL1 mRNA
CTD
PMID:22623647
NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065
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Mki67
marker of proliferation Ki-67
decreases expression
ISO
Azathioprine results in decreased expression of MKI67 mRNA
CTD
PMID:22623647
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mlkl
mixed lineage kinase domain like pseudokinase
decreases expression
ISO
Azathioprine results in decreased expression of MLKL mRNA
CTD
PMID:22623647
NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502
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Mmp10
matrix metallopeptidase 10
decreases expression
ISO
Azathioprine results in decreased expression of MMP10 mRNA
CTD
PMID:19192274
NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
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Mmp12
matrix metallopeptidase 12
decreases expression
ISO
Azathioprine results in decreased expression of MMP12 mRNA
CTD
PMID:19192274
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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Mmp3
matrix metallopeptidase 3
increases expression
ISO
Azathioprine results in increased expression of MMP3 mRNA
CTD
PMID:22623647
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mnd1
meiotic nuclear divisions 1
decreases expression
ISO
Azathioprine results in decreased expression of MND1 mRNA
CTD
PMID:22623647
NCBI chr 2:169,433,523...169,496,081
Ensembl chr 2:169,433,540...169,496,096
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Mns1
meiosis-specific nuclear structural 1
decreases expression
ISO
Azathioprine results in decreased expression of MNS1 mRNA
CTD
PMID:22623647
NCBI chr 8:73,148,877...73,169,570
Ensembl chr 8:73,148,877...73,176,925
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Mocos
molybdenum cofactor sulfurase
multiple interactions
ISO
MOCOS gene SNP results in decreased metabolism of and affects the susceptibility to Azathioprine
CTD
PMID:29935280
NCBI chr18:15,931,659...15,977,415
Ensembl chr18:15,931,654...15,977,187
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Mpc1
mitochondrial pyruvate carrier 1
decreases expression
ISO
Azathioprine results in decreased expression of MPC1 mRNA
CTD
PMID:22623647
NCBI chr 1:52,437,745...52,449,399
Ensembl chr 1:52,437,741...52,449,400
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Msh2
mutS homolog 2
affects response to substance decreases expression
ISO
MSH2 gene mutant form affects the susceptibility to Azathioprine Azathioprine results in decreased expression of MSH2 mRNA
CTD
PMID:20923998 PMID:22623647
NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
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Msh6
mutS homolog 6
decreases expression
ISO
Azathioprine results in decreased expression of MSH6 mRNA
CTD
PMID:22623647
NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
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Msmo1
methylsterol monooxygenase 1
decreases expression
ISO
Azathioprine results in decreased expression of MSMO1 mRNA
CTD
PMID:22623647
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
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Mtarc1
mitochondrial amidoxime reducing component 1
decreases expression
ISO
Azathioprine results in decreased expression of MTARC1 mRNA
CTD
PMID:22623647
NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796
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Mtfr2
mitochondrial fission regulator 2
decreases expression
ISO
Azathioprine results in decreased expression of MTFR2 mRNA
CTD
PMID:22623647
NCBI chr 1:15,123,232...15,138,632
Ensembl chr 1:15,070,894...15,148,832
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Mtor
mechanistic target of rapamycin kinase
increases phosphorylation
ISO
Azathioprine results in increased phosphorylation of MTOR protein
CTD
PMID:23958494
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Muc20
mucin 20, cell surface associated
increases expression
ISO
Azathioprine results in increased expression of MUC20 mRNA
CTD
PMID:22623647
NCBI chr11:67,987,816...68,001,496
Ensembl chr11:67,987,800...68,001,495
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Mx1
MX dynamin like GTPase 1
decreases expression
ISO
Azathioprine results in decreased expression of MX1 mRNA
CTD
PMID:19192274
NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
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Mxd1
max dimerization protein 1
increases expression
ISO
Azathioprine results in increased expression of MXD1 mRNA
CTD
PMID:22623647
NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
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Mybl1
MYB proto-oncogene like 1
decreases expression
ISO
Azathioprine results in decreased expression of MYBL1 mRNA
CTD
PMID:22623647
NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
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Myo5c
myosin VC
decreases expression
ISO
Azathioprine results in decreased expression of MYO5C mRNA
CTD
PMID:22623647
NCBI chr 8:75,989,497...76,066,485
Ensembl chr 8:75,989,528...76,066,483
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Nabp1
nucleic acid binding protein 1
increases expression
ISO
Azathioprine results in increased expression of NABP1 mRNA
CTD
PMID:22623647
NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107
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Nags
N-acetylglutamate synthase
increases expression
ISO
Azathioprine results in increased expression of NAGS mRNA
CTD
PMID:22623647
NCBI chr10:87,098,330...87,102,465
Ensembl chr10:87,098,330...87,102,465
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Nasp
nuclear autoantigenic sperm protein
decreases expression
ISO
Azathioprine results in decreased expression of NASP mRNA
CTD
PMID:22623647
NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928
G
Ncapg
non-SMC condensin I complex, subunit G
decreases expression
ISO
Azathioprine results in decreased expression of NCAPG mRNA
CTD
PMID:22623647
NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902
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Ncapg2
non-SMC condensin II complex, subunit G2
decreases expression
ISO
Azathioprine results in decreased expression of NCAPG2 mRNA
CTD
PMID:22623647
NCBI chr 6:137,342,449...137,418,083
Ensembl chr 6:137,342,943...137,415,159
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Ncaph
non-SMC condensin I complex, subunit H
decreases expression
ISO
Azathioprine results in decreased expression of NCAPH mRNA
CTD
PMID:22623647
NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180
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Ncf2
neutrophil cytosolic factor 2
increases expression
ISO
Azathioprine results in increased expression of NCF2 mRNA
CTD
PMID:22623647
NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
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Ndc80
NDC80 kinetochore complex component
decreases expression
ISO
Azathioprine results in decreased expression of NDC80 mRNA
CTD
PMID:22623647
NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
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Ndrg1
N-myc downstream regulated 1
increases expression
ISO
Azathioprine results in increased expression of NDRG1 mRNA
CTD
PMID:22623647
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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Ndufa4l2
NDUFA4, mitochondrial complex associated like 2
decreases expression
ISO
Azathioprine results in decreased expression of NDUFA4L2 mRNA
CTD
PMID:19192274
NCBI chr 7:63,351,021...63,359,010
Ensembl chr 7:63,356,883...63,359,010
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Nek2
NIMA-related kinase 2
decreases expression
ISO
Azathioprine results in decreased expression of NEK2 mRNA
CTD
PMID:22623647
NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions
ISO
NFE2L2 protein affects the reaction [Azathioprine results in increased activity of NQO1 protein]
CTD
PMID:21803983
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfe2l3
NFE2 like bZIP transcription factor 3
decreases expression
ISO
Azathioprine results in decreased expression of NFE2L3 mRNA
CTD
PMID:22623647
NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629
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Nid2
nidogen 2
increases expression
ISO
Azathioprine results in increased expression of NID2 mRNA
CTD
PMID:19192274
NCBI chr15:4,458,082...4,513,808
Ensembl chr15:4,458,084...4,513,843
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Nlrp3
NLR family, pyrin domain containing 3
increases expression
ISO
Azathioprine results in increased expression of NLRP3 mRNA
CTD
PMID:24184165
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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Nmb
neuromedin B
decreases expression
ISO
Azathioprine results in decreased expression of NMB mRNA
CTD
PMID:19192274
NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190
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Nos2
nitric oxide synthase 2
decreases expression
ISO
Azathioprine results in decreased expression of NOS2 mRNA; Azathioprine results in decreased expression of NOS2 protein
CTD
PMID:16473374
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Npnt
nephronectin
decreases expression
ISO
Azathioprine results in decreased expression of NPNT mRNA
CTD
PMID:22623647
NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases activity multiple interactions
ISO
Azathioprine results in increased activity of NQO1 protein NFE2L2 protein affects the reaction [Azathioprine results in increased activity of NQO1 protein]
CTD
PMID:21803983
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr2f2
nuclear receptor subfamily 2, group F, member 2
decreases expression
ISO
Azathioprine results in decreased expression of NR2F2 mRNA
CTD
PMID:22623647
NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
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Nr4a3
nuclear receptor subfamily 4, group A, member 3
decreases expression
ISO
Azathioprine results in decreased expression of NR4A3 mRNA
CTD
PMID:19192274
NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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Nuf2
NUF2 component of NDC80 kinetochore complex
decreases expression
ISO
Azathioprine results in decreased expression of NUF2 mRNA
CTD
PMID:22623647
NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
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Nusap1
nucleolar and spindle associated protein 1
decreases expression
ISO
Azathioprine results in decreased expression of NUSAP1 mRNA
CTD
PMID:22623647
NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
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Oas1a
2'-5' oligoadenylate synthetase 1A
decreases expression
ISO
Azathioprine results in decreased expression of OAS1 mRNA
CTD
PMID:19192274
NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517
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Oas3
2'-5'-oligoadenylate synthetase 3
decreases expression
ISO
Azathioprine results in decreased expression of OAS3 mRNA
CTD
PMID:19192274
NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781
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Odam
odontogenic, ameloblast associated
decreases expression
ISO
Azathioprine results in decreased expression of ODAM mRNA
CTD
PMID:22623647
NCBI chr14:20,193,286...20,202,517
Ensembl chr14:20,193,302...20,202,517
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Oip5
Opa interacting protein 5
decreases expression
ISO
Azathioprine results in decreased expression of OIP5 mRNA
CTD
PMID:22623647
NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250
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Olfml2b
olfactomedin-like 2B
increases expression
ISO
Azathioprine results in increased expression of OLFML2B mRNA
CTD
PMID:19192274
NCBI chr13:82,869,414...82,906,607
Ensembl chr13:82,869,433...82,906,607
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Orc1
origin recognition complex, subunit 1
decreases expression
ISO
Azathioprine results in decreased expression of ORC1 mRNA
CTD
PMID:22623647
NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
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Orc6
origin recognition complex, subunit 6
decreases expression
ISO
Azathioprine results in decreased expression of ORC6 mRNA
CTD
PMID:22623647
NCBI chr19:21,757,867...21,765,638
Ensembl chr19:21,757,866...21,765,662
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Orm1
orosomucoid 1
multiple interactions
EXP
[Carbon Tetrachloride co-treated with Azathioprine] results in decreased expression of ORM1 protein
CTD
PMID:8614026
NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
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Osgin1
oxidative stress induced growth inhibitor 1
increases expression
ISO
Azathioprine results in increased expression of OSGIN1 mRNA
CTD
PMID:22623647
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
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Paep
progestagen associated endometrial protein
increases expression
ISO
Azathioprine results in increased expression of PAEP mRNA
CTD
PMID:22623647
NCBI chr 3:8,531,136...8,534,430
Ensembl chr 3:8,531,138...8,534,430
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Pah
phenylalanine hydroxylase
decreases expression
ISO
Azathioprine results in decreased expression of PAH mRNA
CTD
PMID:22623647
NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
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Palld
palladin, cytoskeletal associated protein
increases expression
ISO
Azathioprine results in increased expression of PALLD mRNA
CTD
PMID:22623647
NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337
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Pank1
pantothenate kinase 1
decreases expression
ISO
Azathioprine results in decreased expression of PANK1 mRNA
CTD
PMID:22623647
NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
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Paqr5
progestin and adipoQ receptor family member 5
increases expression
ISO
Azathioprine results in increased expression of PAQR5 mRNA
CTD
PMID:22623647
NCBI chr 8:62,431,867...62,513,688
Ensembl chr 8:62,431,867...62,513,688
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Paqr9
progestin and adipoQ receptor family member 9
decreases expression
ISO
Azathioprine results in decreased expression of PAQR9 mRNA
CTD
PMID:22623647
NCBI chr 8:96,114,249...96,116,546
G
Parpbp
PARP1 binding protein
decreases expression
ISO
Azathioprine results in decreased expression of PARPBP mRNA
CTD
PMID:22623647
NCBI chr 7:22,511,427...22,580,834
Ensembl chr 7:22,511,427...22,573,695
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Pask
PAS domain containing serine/threonine kinase
decreases expression
ISO
Azathioprine results in decreased expression of PASK mRNA
CTD
PMID:22623647
NCBI chr 9:93,844,275...93,886,036
Ensembl chr 9:93,844,278...93,885,111
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Pbk
PDZ binding kinase
decreases expression
ISO
Azathioprine results in decreased expression of PBK mRNA
CTD
PMID:22623647
NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
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Pbx3
PBX homeobox 3
decreases expression
ISO
Azathioprine results in decreased expression of PBX3 mRNA
CTD
PMID:22623647
NCBI chr 3:17,488,691...17,682,412
Ensembl chr 3:17,488,693...17,682,791
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Pck1
phosphoenolpyruvate carboxykinase 1
decreases expression
ISO
Azathioprine results in decreased expression of PCK1 mRNA
CTD
PMID:22623647
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Pclaf
PCNA clamp associated factor
decreases expression
ISO
Azathioprine results in decreased expression of PCLAF mRNA
CTD
PMID:22623647
NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994 Ensembl chr 8:66,420,587...66,432,994
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Pcna
proliferating cell nuclear antigen
decreases expression
ISO
Azathioprine results in decreased expression of PCNA mRNA
CTD
PMID:22623647
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pdgfa
platelet derived growth factor subunit A
increases expression
ISO
Azathioprine results in increased expression of PDGFA mRNA
CTD
PMID:22623647
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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Peg10
paternally expressed 10
decreases expression
ISO
Azathioprine results in decreased expression of PEG10 mRNA
CTD
PMID:22623647
NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621
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Phgdh
phosphoglycerate dehydrogenase
decreases expression
ISO
Azathioprine results in decreased expression of PHGDH mRNA
CTD
PMID:19192274
NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
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Phlda2
pleckstrin homology-like domain, family A, member 2
increases expression
ISO
Azathioprine results in increased expression of PHLDA2 mRNA
CTD
PMID:22623647
NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836
G
Pif1
PIF1 5'-to-3' DNA helicase
decreases expression
ISO
Azathioprine results in decreased expression of PIF1 mRNA
CTD
PMID:22623647
NCBI chr 8:66,110,641...66,120,202
Ensembl chr 8:66,111,072...66,120,200
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Piga
phosphatidylinositol glycan anchor biosynthesis, class A
affects mutagenesis
EXP
Azathioprine affects the mutagenesis of PIGA
CTD
PMID:22923490
NCBI chr X:30,043,033...30,055,861
Ensembl chr X:30,042,343...30,055,804
G
Pilra
paired immunoglobin-like type 2 receptor alpha
decreases expression
ISO
Azathioprine results in decreased expression of PILRA mRNA
CTD
PMID:19192274
NCBI chr12:17,787,169...17,798,149
Ensembl chr12:17,787,127...17,798,094
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Pim1
Pim-1 proto-oncogene, serine/threonine kinase
increases expression
ISO
Azathioprine results in increased expression of PIM1 mRNA
CTD
PMID:22623647
NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
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Pimreg
PICALM interacting mitotic regulator
decreases expression
ISO
Azathioprine results in decreased expression of PIMREG mRNA
CTD
PMID:22623647
NCBI chr10:56,669,603...56,674,540
Ensembl chr10:56,669,675...56,674,791
G
Pip5k1b
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
decreases expression
ISO
Azathioprine results in decreased expression of PIP5K1B mRNA
CTD
PMID:22623647
NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:221,914,159...222,183,672
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Plk3
polo-like kinase 3
increases expression
ISO
Azathioprine results in increased expression of PLK3 mRNA
CTD
PMID:22623647
NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
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Plpp3
phospholipid phosphatase 3
decreases expression
ISO
Azathioprine results in decreased expression of PLPP3 mRNA
CTD
PMID:19192274
NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
G
Plppr1
phospholipid phosphatase related 1
decreases expression
ISO
Azathioprine results in decreased expression of LPPR1 mRNA
CTD
PMID:22623647
NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835
G
Pnpla3
patatin-like phospholipase domain containing 3
decreases expression
ISO
Azathioprine results in decreased expression of PNPLA3 mRNA
CTD
PMID:22623647
NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
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Poglut3
protein O-glucosyltransferase 3
decreases expression
ISO
Azathioprine results in decreased expression of POGLUT3 mRNA
CTD
PMID:22623647
NCBI chr 8:53,777,614...53,795,404
Ensembl chr 8:53,777,785...53,795,399
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Pola1
DNA polymerase alpha 1, catalytic subunit
decreases expression
ISO
Azathioprine results in decreased expression of POLA1 mRNA
CTD
PMID:22623647
NCBI chr X:58,034,617...58,348,612
Ensembl chr X:58,034,619...58,348,536
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Pold3
DNA polymerase delta 3, accessory subunit
decreases expression
ISO
Azathioprine results in decreased expression of POLD3 mRNA
CTD
PMID:22623647
NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665
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Pold4
DNA polymerase delta 4, accessory subunit
increases expression
ISO
Azathioprine results in increased expression of POLD4 mRNA
CTD
PMID:22623647
NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401
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Pole2
DNA polymerase epsilon 2, accessory subunit
decreases expression
ISO
Azathioprine results in decreased expression of POLE2 mRNA
CTD
PMID:22623647
NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305
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Ppl
periplakin
increases expression
ISO
Azathioprine results in increased expression of PPL mRNA
CTD
PMID:22623647
NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575
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Ppm1h
protein phosphatase, Mg2+/Mn2+ dependent, 1H
decreases expression
ISO
Azathioprine results in decreased expression of PPM1H mRNA
CTD
PMID:22623647
NCBI chr 7:58,338,661...58,599,547
Ensembl chr 7:58,338,661...58,599,547
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
ISO
Azathioprine results in increased expression of PPP1R15A mRNA
CTD
PMID:22623647
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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Ppp1r18
protein phosphatase 1, regulatory subunit 18
increases expression
ISO
Azathioprine results in increased expression of PPP1R18 mRNA
CTD
PMID:22623647
NCBI chr20:2,877,567...2,887,526
Ensembl chr20:2,877,567...2,891,802
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Ppp1r3c
protein phosphatase 1, regulatory subunit 3C
decreases expression
ISO
Azathioprine results in decreased expression of PPP1R3C mRNA
CTD
PMID:22623647
NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
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Ppp4r2
protein phosphatase 4, regulatory subunit 2
increases expression
ISO
Azathioprine results in increased expression of PPP4R2 mRNA
CTD
PMID:19192274
NCBI chr 4:133,454,555...133,495,486
Ensembl chr 4:133,454,555...133,495,486
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Prag1
PEAK1 related kinase activating pseudokinase 1
increases expression
ISO
Azathioprine results in increased expression of PRAG1 mRNA
CTD
PMID:22623647
NCBI chr16:56,087,885...56,141,153
Ensembl chr16:56,087,885...56,141,153
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Prc1
protein regulator of cytokinesis 1
decreases expression
ISO
Azathioprine results in decreased expression of PRC1 mRNA
CTD
PMID:22623647
NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
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Prim1
DNA primase subunit 1
decreases expression
ISO
Azathioprine results in decreased expression of PRIM1 mRNA
CTD
PMID:22623647
NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526
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Prom1
prominin 1
decreases expression
ISO
Azathioprine results in decreased expression of PROM1 mRNA
CTD
PMID:22623647
NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
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Psmb9
proteasome 20S subunit beta 9
decreases expression
ISO
Azathioprine results in decreased expression of PSMB9 mRNA
CTD
PMID:22623647
NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
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Psrc1
proline and serine rich coiled-coil 1
decreases expression
ISO
Azathioprine results in decreased expression of PSRC1 mRNA
CTD
PMID:22623647
NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874
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Ptch1
patched 1
affects mutagenesis
ISO
Azathioprine affects the mutagenesis of PTCH1 gene
CTD
PMID:18854826
NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
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Ptgr1
prostaglandin reductase 1
increases expression
ISO
Azathioprine results in increased expression of PTGR1 mRNA
CTD
PMID:22623647
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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Ptgs2
prostaglandin-endoperoxide synthase 2
decreases expression
ISO
Azathioprine results in decreased expression of PTGS2 mRNA
CTD
PMID:19192274
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Pxdc1
PX domain containing 1
increases expression
ISO
Azathioprine results in increased expression of PXDC1 mRNA
CTD
PMID:22623647
NCBI chr17:30,275,998...30,304,971
Ensembl chr17:30,276,377...30,304,973
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Pxylp1
2-phosphoxylose phosphatase 1
decreases expression
ISO
Azathioprine results in decreased expression of PXYLP1 mRNA
CTD
PMID:22623647
NCBI chr 8:97,419,766...97,485,163
Ensembl chr 8:97,419,776...97,485,064
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Rab11fip4
RAB11 family interacting protein 4
decreases expression
ISO
Azathioprine results in decreased expression of RAB11FIP4 mRNA
CTD
PMID:22623647
NCBI chr10:64,550,109...64,658,123
Ensembl chr10:64,550,177...64,654,759
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Rac1
Rac family small GTPase 1
multiple interactions decreases activity affects binding affects response to substance
ISO
Azathioprine inhibits the reaction [RAC1 protein binds to STAT3 protein] Azathioprine results in decreased activity of RAC1 protein Azathioprine metabolite binds to RAC1 protein RAC1 gene polymorphism affects the susceptibility to Azathioprine
CTD
PMID:12697733 PMID:21372752
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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Racgap1
Rac GTPase-activating protein 1
decreases expression
ISO
Azathioprine results in decreased expression of RACGAP1 mRNA
CTD
PMID:22623647
NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
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Rad51ap1
RAD51 associated protein 1
decreases expression
ISO
Azathioprine results in decreased expression of RAD51AP1 mRNA
CTD
PMID:22623647
NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524
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Rad54b
RAD54 homolog B
decreases expression
ISO
Azathioprine results in decreased expression of RAD54B mRNA
CTD
PMID:22623647
NCBI chr 5:25,032,112...25,104,630
Ensembl chr 5:25,032,066...25,104,616
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Rap1gap
Rap1 GTPase-activating protein
increases expression
ISO
Azathioprine results in increased expression of RAP1GAP mRNA
CTD
PMID:26198647
NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253
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Rarres1
retinoic acid receptor responder 1
increases expression
ISO
Azathioprine results in increased expression of RARRES1 mRNA
CTD
PMID:19192274
NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
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Rasd1
ras related dexamethasone induced 1
increases expression
ISO
Azathioprine results in increased expression of RASD1 mRNA
CTD
PMID:22623647
NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
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Rbm24
RNA binding motif protein 24
increases expression
ISO
Azathioprine results in increased expression of RBM24 mRNA
CTD
PMID:22623647
NCBI chr17:18,275,681...18,288,231
Ensembl chr17:18,275,688...18,288,102
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Rbpms2
RNA binding protein, mRNA processing factor 2
increases expression
ISO
Azathioprine results in increased expression of RBPMS2 mRNA
CTD
PMID:22623647
NCBI chr 8:66,153,169...66,184,278
Ensembl chr 8:66,153,593...66,184,268
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Reck
reversion-inducing-cysteine-rich protein with kazal motifs
decreases expression
ISO
Azathioprine results in decreased expression of RECK mRNA
CTD
PMID:22623647
NCBI chr 5:58,102,961...58,169,516
Ensembl chr 5:58,102,981...58,169,502
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Rfc3
replication factor C subunit 3
decreases expression
ISO
Azathioprine results in decreased expression of RFC3 mRNA
CTD
PMID:22623647
NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778
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Rfc5
replication factor C subunit 5
decreases expression
ISO
Azathioprine results in decreased expression of RFC5 mRNA
CTD
PMID:22623647
NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
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Rgcc
regulator of cell cycle
increases expression
ISO
Azathioprine results in increased expression of RGCC mRNA
CTD
PMID:22623647
NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
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Rgs4
regulator of G-protein signaling 4
decreases expression
ISO
Azathioprine results in decreased expression of RGS4 mRNA
CTD
PMID:19192274
NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
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Rhbdd1
rhomboid domain containing 1
increases expression
ISO
Azathioprine results in increased expression of RHBDD1 mRNA
CTD
PMID:22623647
NCBI chr 9:83,630,037...83,748,690
Ensembl chr 9:83,630,063...83,748,689
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Rhno1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
decreases expression
ISO
Azathioprine results in decreased expression of RHNO1 mRNA
CTD
PMID:22623647
NCBI chr 4:161,634,047...161,639,437
Ensembl chr 4:161,634,048...161,639,371
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Rhobtb1
Rho-related BTB domain containing 1
decreases expression
ISO
Azathioprine results in decreased expression of RHOBTB1 mRNA
CTD
PMID:22623647
NCBI chr20:19,327,142...19,456,121
Ensembl chr20:19,327,155...19,403,012
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Rhoc
ras homolog family member C
increases expression
ISO
Azathioprine results in increased expression of RHOC mRNA
CTD
PMID:22623647
NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
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Rida
reactive intermediate imine deaminase A homolog
decreases expression
ISO
Azathioprine results in decreased expression of RIDA mRNA
CTD
PMID:22623647
NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716
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Rig1
RNA sensor RIG-1
decreases expression
ISO
Azathioprine results in decreased expression of RIGI mRNA
CTD
PMID:19192274
NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819
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Rin2
Ras and Rab interactor 2
increases expression
ISO
Azathioprine results in increased expression of RIN2 mRNA
CTD
PMID:22623647
NCBI chr 3:133,086,858...133,303,604
Ensembl chr 3:133,086,749...133,303,604
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Ripk2
receptor-interacting serine-threonine kinase 2
decreases expression
ISO
Azathioprine results in decreased expression of RIPK2 mRNA
CTD
PMID:19192274
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
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Rit1
Ras-like without CAAX 1
increases expression
ISO
Azathioprine results in increased expression of RIT1 mRNA
CTD
PMID:22623647
NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455
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Rmi2
RecQ mediated genome instability 2
decreases expression
ISO
Azathioprine results in decreased expression of RMI2 mRNA
CTD
PMID:22623647
NCBI chr10:4,829,333...4,837,264
Ensembl chr10:4,830,553...4,837,235
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Rnase4
ribonuclease A family member 4
decreases expression
ISO
Azathioprine results in decreased expression of RNASE4 mRNA
CTD
PMID:22623647
NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
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Rnf144a
ring finger protein 144A
decreases expression
ISO
Azathioprine results in decreased expression of RNF144A mRNA
CTD
PMID:22623647
NCBI chr 6:42,899,767...43,019,769
Ensembl chr 6:42,903,174...43,020,012
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Rnf19b
ring finger protein 19B
decreases expression
ISO
Azathioprine results in decreased expression of RNF19B mRNA
CTD
PMID:19192274
NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:141,406,118...141,431,380
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Rps6kb1
ribosomal protein S6 kinase B1
multiple interactions decreases phosphorylation increases phosphorylation
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Azathioprine results in increased phosphorylation of RPS6KB1 protein] Azathioprine results in decreased phosphorylation of RPS6KB1 protein
CTD
PMID:23958494
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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Rras2
RAS related 2
increases expression
ISO
Azathioprine results in increased expression of RRAS2 mRNA
CTD
PMID:26198647
NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
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Rrm1
ribonucleotide reductase catalytic subunit M1
decreases expression
ISO
Azathioprine results in decreased expression of RRM1 mRNA
CTD
PMID:22623647
NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
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Rrm2
ribonucleotide reductase regulatory subunit M2
decreases expression
ISO
Azathioprine results in decreased expression of RRM2 mRNA
CTD
PMID:22623647
NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
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Rsad2
radical S-adenosyl methionine domain containing 2
decreases expression
ISO
Azathioprine results in decreased expression of RSAD2 mRNA
CTD
PMID:19192274
NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
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RT1-Ba
RT1 class II, locus Ba
affects response to substance
ISO
HLA-DQA1 gene polymorphism affects the susceptibility to Azathioprine
CTD
PMID:25217962
NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
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RT1-Db1
RT1 class II, locus Db1
affects response to substance
ISO
HLA-DRB1 gene polymorphism affects the susceptibility to Azathioprine
CTD
PMID:25217962
NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
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S100a11
S100 calcium binding protein A11
increases expression
ISO
Azathioprine results in increased expression of S100A11 mRNA
CTD
PMID:22623647
NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
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S100a8
S100 calcium binding protein A8
increases expression
ISO
Azathioprine results in increased expression of S100A8 mRNA
CTD
PMID:24184165
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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S100a9
S100 calcium binding protein A9
increases expression
ISO
Azathioprine results in increased expression of S100A9 mRNA
CTD
PMID:24184165
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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Sall1
spalt-like transcription factor 1
decreases expression
ISO
Azathioprine results in decreased expression of SALL1 mRNA
CTD
PMID:22623647
NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705
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Sapcd2
suppressor APC domain containing 2
decreases expression
ISO
Azathioprine results in decreased expression of SAPCD2 mRNA
CTD
PMID:22623647
NCBI chr 3:8,186,089...8,195,119
Ensembl chr 3:8,187,266...8,192,546
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Scml1
Scm polycomb group protein like 1
decreases expression
ISO
Azathioprine results in decreased expression of SCML1 mRNA
CTD
PMID:22623647
NCBI chr X:32,893,100...32,912,686
Ensembl chr X:32,894,327...32,911,366
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Scn1a
sodium voltage-gated channel alpha subunit 1
decreases expression
ISO
Azathioprine results in decreased expression of SCN1A mRNA
CTD
PMID:22623647
NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699
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Sel1l3
SEL1L family member 3
increases expression
ISO
Azathioprine results in increased expression of SEL1L3 mRNA
CTD
PMID:22623647
NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644
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Serinc2
serine incorporator 2
increases expression
ISO
Azathioprine results in increased expression of SERINC2 mRNA
CTD
PMID:22623647
NCBI chr 5:142,592,308...142,614,628
Ensembl chr 5:142,592,309...142,618,364
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Serinc3
serine incorporator 3
increases expression
ISO
Azathioprine results in increased expression of SERINC3 mRNA
CTD
PMID:21621594
NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808
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Serpina1
serpin family A member 1
multiple interactions
EXP
[Carbon Tetrachloride co-treated with Azathioprine] results in increased expression of SERPINA1 protein
CTD
PMID:8614026
NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
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Serpina7
serpin family A member 7
decreases expression
ISO
Azathioprine results in decreased expression of SERPINA7 mRNA
CTD
PMID:22623647
NCBI chr X:102,663,242...102,722,319
Ensembl chr X:102,663,405...102,669,040
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Serpine1
serpin family E member 1
increases expression
ISO
Azathioprine results in increased expression of SERPINE1 mRNA
CTD
PMID:22623647
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Serpine2
serpin family E member 2
increases expression
ISO
Azathioprine results in increased expression of SERPINE2 mRNA
CTD
PMID:22623647
NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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Sertad1
SERTA domain containing 1
increases expression
ISO
Azathioprine results in increased expression of SERTAD1 mRNA
CTD
PMID:22623647
NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091
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Sesn2
sestrin 2
increases expression
ISO
Azathioprine results in increased expression of SESN2 mRNA
CTD
PMID:22623647
NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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Sfn
stratifin
increases expression
ISO
Azathioprine results in increased expression of SFN mRNA
CTD
PMID:22623647
NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314
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Sgk1
serum/glucocorticoid regulated kinase 1
decreases expression
ISO
Azathioprine results in decreased expression of SGK1 mRNA
CTD
PMID:22623647
NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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Sgo2
shugoshin 2
decreases expression
ISO
Azathioprine results in decreased expression of SGO2 mRNA
CTD
PMID:22623647
NCBI chr 9:59,548,605...59,573,229
Ensembl chr 9:59,548,683...59,573,229
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Sh2d5
SH2 domain containing 5
increases expression
ISO
Azathioprine results in increased expression of SH2D5 mRNA
CTD
PMID:22623647
NCBI chr 5:150,469,738...150,480,615
Ensembl chr 5:150,467,728...150,479,955
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Sh3rf1
SH3 domain containing ring finger 1
increases expression
ISO
Azathioprine results in increased expression of SH3RF1 mRNA
CTD
PMID:22623647
NCBI chr16:28,735,522...28,901,261
Ensembl chr16:28,735,440...28,901,644
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Shb
SH2 domain containing adaptor protein B
increases expression
ISO
Azathioprine results in increased expression of SHB mRNA
CTD
PMID:22623647
NCBI chr 5:59,678,066...59,785,443
Ensembl chr 5:59,678,216...59,785,538
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Shcbp1
SHC binding and spindle associated 1
decreases expression
ISO
Azathioprine results in decreased expression of SHCBP1 mRNA
CTD
PMID:22623647
NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844
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Shmt1
serine hydroxymethyltransferase 1
decreases expression
ISO
Azathioprine results in decreased expression of SHMT1 mRNA
CTD
PMID:22623647
NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820
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Ska1
spindle and kinetochore associated complex subunit 1
decreases expression
ISO
Azathioprine results in decreased expression of SKA1 mRNA
CTD
PMID:22623647
NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037
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Skp2
S-phase kinase associated protein 2
decreases expression
ISO
Azathioprine results in decreased expression of SKP2 mRNA
CTD
PMID:22623647
NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
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Slbp
stem-loop histone mRNA binding protein
decreases expression
ISO
Azathioprine results in decreased expression of SLBP mRNA
CTD
PMID:22623647
NCBI chr14:77,071,441...77,081,911
Ensembl chr14:77,071,632...77,081,906
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Slc10a1
solute carrier family 10 member 1
decreases expression
EXP
Azathioprine results in decreased expression of SLC10A1 mRNA
CTD
PMID:27765674
NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
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Slc15a1
solute carrier family 15 member 1
decreases expression
ISO
Azathioprine results in decreased expression of SLC15A1 mRNA
CTD
PMID:12806628
NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545
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Slc16a10
solute carrier family 16 member 10
decreases expression
ISO
Azathioprine results in decreased expression of SLC16A10 mRNA
CTD
PMID:22623647
NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
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Slc16a6
solute carrier family 16, member 6
increases expression
ISO
Azathioprine results in increased expression of SLC16A6 mRNA
CTD
PMID:22623647
NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779
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Slc20a1
solute carrier family 20 member 1
increases expression
ISO
Azathioprine results in increased expression of SLC20A1 mRNA
CTD
PMID:22623647
NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
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Slc22a15
solute carrier family 22, member 15
increases expression
ISO
Azathioprine results in increased expression of SLC22A15 mRNA
CTD
PMID:22623647
NCBI chr 2:189,298,836...189,359,902
Ensembl chr 2:189,298,832...189,358,792
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Slc22a18
solute carrier family 22, member 18
increases expression
ISO
Azathioprine results in increased expression of SLC22A18 mRNA
CTD
PMID:22623647
NCBI chr 1:198,670,626...198,694,977
Ensembl chr 1:198,671,731...198,694,975
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Slc2a10
solute carrier family 2 member 10
decreases expression
ISO
Azathioprine results in decreased expression of SLC2A10 mRNA
CTD
PMID:22623647
NCBI chr 3:154,240,395...154,252,690
Ensembl chr 3:154,240,391...154,252,690
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Slc2a2
solute carrier family 2 member 2
decreases expression
ISO
Azathioprine results in decreased expression of SLC2A2 mRNA
CTD
PMID:22623647
NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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Slc30a10
solute carrier family 30, member 10
decreases expression
ISO
Azathioprine results in decreased expression of SLC30A10 mRNA
CTD
PMID:22623647
NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103
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Slc38a11
solute carrier family 38, member 11
decreases expression
ISO
Azathioprine results in decreased expression of SLC38A11 mRNA
CTD
PMID:22623647
NCBI chr 3:49,987,119...50,033,615
Ensembl chr 3:49,987,124...50,033,615
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Slc3a2
solute carrier family 3 member 2
increases expression
ISO
Azathioprine results in increased expression of SLC3A2 mRNA
CTD
PMID:22623647
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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Slc40a1
solute carrier family 40 member 1
increases expression
ISO
Azathioprine results in increased expression of SLC40A1 mRNA
CTD
PMID:22623647
NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
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Slc44a3
solute carrier family 44, member 3
decreases expression
ISO
Azathioprine results in decreased expression of SLC44A3 mRNA
CTD
PMID:22623647
NCBI chr 2:209,552,138...209,628,182
Ensembl chr 2:209,552,144...209,629,044
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Slc5a9
solute carrier family 5 member 9
decreases expression
ISO
Azathioprine results in decreased expression of SLC5A9 mRNA
CTD
PMID:22623647
NCBI chr 5:126,709,762...126,733,468
Ensembl chr 5:126,709,769...126,733,468
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Slc66a1
solute carrier family 66 member 1
increases expression
ISO
Azathioprine results in increased expression of SLC66A1 mRNA
CTD
PMID:22623647
NCBI chr 5:151,537,870...151,552,259
Ensembl chr 5:151,542,376...151,552,259
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Slc6a14
solute carrier family 6 member 14
decreases expression
ISO
Azathioprine results in decreased expression of SLC6A14 mRNA
CTD
PMID:22623647
NCBI chr X:112,314,643...112,375,412
Ensembl chr X:112,314,691...112,375,096
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Slc6a6
solute carrier family 6 member 6
increases expression
ISO
Azathioprine results in increased expression of SLC6A6 mRNA
CTD
PMID:22623647
NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
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Slc7a11
solute carrier family 7 member 11
decreases expression increases expression
ISO
Azathioprine results in decreased expression of SLC7A11 mRNA Azathioprine results in increased expression of SLC7A11 mRNA
CTD
PMID:19192274 PMID:22623647 PMID:26198647
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Slco4c1
solute carrier organic anion transporter family, member 4C1
decreases expression
ISO
Azathioprine results in decreased expression of SLCO4C1 mRNA
CTD
PMID:22623647
NCBI chr 9:97,177,497...97,229,161
Ensembl chr 9:97,178,861...97,229,715
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Slf1
SMC5-SMC6 complex localization factor 1
decreases expression
ISO
Azathioprine results in decreased expression of SLF1 mRNA
CTD
PMID:22623647
NCBI chr 2:6,767,015...6,874,428
Ensembl chr 2:6,767,015...6,867,149
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Smc2
structural maintenance of chromosomes 2
decreases expression
ISO
Azathioprine results in decreased expression of SMC2 mRNA
CTD
PMID:22623647
NCBI chr 5:66,806,882...66,853,478
Ensembl chr 5:66,807,011...66,853,242
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Smc4
structural maintenance of chromosomes 4
decreases expression
ISO
Azathioprine results in decreased expression of SMC4 mRNA
CTD
PMID:22623647
NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
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Smox
spermine oxidase
increases expression
ISO
Azathioprine results in increased expression of SMOX mRNA
CTD
PMID:22623647
NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710 Ensembl chr X:118,731,900...118,765,710
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Sms
spermine synthase
decreases expression
ISO
Azathioprine results in decreased expression of SMS mRNA
CTD
PMID:19192274
NCBI chr X:37,516,949...37,572,657
Ensembl chr X:37,516,931...37,570,822 Ensembl chr 3:37,516,931...37,570,822
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Sod2
superoxide dismutase 2
increases expression decreases expression
ISO
Azathioprine results in increased expression of SOD2 mRNA Azathioprine results in decreased expression of SOD2 mRNA
CTD
PMID:18222062 PMID:19192274
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sorbs2
sorbin and SH3 domain containing 2
decreases expression
ISO
Azathioprine results in decreased expression of SORBS2 mRNA
CTD
PMID:22623647
NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514
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Sp5
Sp5 transcription factor
decreases expression
ISO
Azathioprine results in decreased expression of SP5 mRNA
CTD
PMID:22623647
NCBI chr 3:55,274,931...55,277,733
Ensembl chr 3:55,274,931...55,277,733
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Spag5
sperm associated antigen 5
decreases expression
ISO
Azathioprine results in decreased expression of SPAG5 mRNA
CTD
PMID:22623647
NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
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Spc25
SPC25 component of NDC80 kinetochore complex
decreases expression
ISO
Azathioprine results in decreased expression of SPC25 mRNA
CTD
PMID:22623647
NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
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Spdl1
spindle apparatus coiled-coil protein 1
decreases expression
ISO
Azathioprine results in decreased expression of SPDL1 mRNA
CTD
PMID:22623647
NCBI chr10:19,269,125...19,294,213
Ensembl chr10:19,269,127...19,294,127
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Spin4
spindlin family, member 4
decreases expression
ISO
Azathioprine results in decreased expression of SPIN4 mRNA
CTD
PMID:22623647
NCBI chr X:59,888,728...59,892,817
Ensembl chr X:59,891,581...59,892,330
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Spink1
serine peptidase inhibitor, Kazal type 1
increases expression
ISO EXP
Azathioprine results in increased expression of SPINK1 mRNA
CTD
PMID:28138970
NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
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Spon1
spondin 1
increases expression
ISO
Azathioprine results in increased expression of SPON1 mRNA
CTD
PMID:19192274
NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
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Spry4
sprouty RTK signaling antagonist 4
increases expression
ISO
Azathioprine results in increased expression of SPRY4 mRNA
CTD
PMID:22623647
NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004
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Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
increases expression
ISO
Azathioprine results in increased expression of SPSB1 mRNA
CTD
PMID:22623647
NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468
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Sptlc3
serine palmitoyltransferase, long chain base subunit 3
decreases expression
ISO
Azathioprine results in decreased expression of SPTLC3 mRNA
CTD
PMID:22623647
NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010
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Sqle
squalene epoxidase
decreases expression
ISO
Azathioprine results in decreased expression of SQLE mRNA
CTD
PMID:22623647
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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Sqstm1
sequestosome 1
increases expression
ISO
Azathioprine results in increased expression of SQSTM1 mRNA
CTD
PMID:22623647 PMID:26198647
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Srxn1
sulfiredoxin 1
increases expression
ISO
Azathioprine results in increased expression of SRXN1 mRNA Azathioprine results in increased expression of SRXN1 protein
CTD
PMID:22623647 PMID:26198647 PMID:27358234
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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Stat1
signal transducer and activator of transcription 1
decreases expression
ISO
Azathioprine results in decreased expression of STAT1 mRNA
CTD
PMID:19192274
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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Stat3
signal transducer and activator of transcription 3
multiple interactions
ISO
Azathioprine inhibits the reaction [RAC1 protein binds to STAT3 protein]
CTD
PMID:12697733
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Stil
STIL, centriolar assembly protein
decreases expression
ISO
Azathioprine results in decreased expression of STIL mRNA
CTD
PMID:22623647
NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730
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Stmn1
stathmin 1
decreases expression
ISO
Azathioprine results in decreased expression of STMN1 mRNA
CTD
PMID:22623647
NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
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Sts
steroid sulfatase
increases expression
ISO
Azathioprine results in increased expression of STS mRNA
CTD
PMID:19192274
NCBI chr X:42,225,131...42,233,403
Ensembl chr X:42,225,372...42,233,402
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Stx3
syntaxin 3
increases expression
ISO
Azathioprine results in increased expression of STX3 mRNA
CTD
PMID:22623647
NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805
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Sync
syncoilin, intermediate filament protein
decreases expression
ISO
Azathioprine results in decreased expression of SYNC mRNA
CTD
PMID:22623647
NCBI chr 5:141,631,837...141,656,184
Ensembl chr 5:141,632,367...141,688,659
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Tafa5
TAFA chemokine like family member 5
decreases expression
ISO
Azathioprine results in decreased expression of TAFA5 mRNA
CTD
PMID:21621594
NCBI chr 7:118,613,731...118,835,016
Ensembl chr 7:118,613,889...118,834,353
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Tbc1d8b
TBC1 domain family member 8B
decreases expression
ISO
Azathioprine results in decreased expression of TBC1D8B mRNA
CTD
PMID:22623647
NCBI chr X:103,319,181...103,407,137
Ensembl chr X:103,319,340...103,407,133
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Tbx21
T-box transcription factor 21
increases expression
ISO
Azathioprine results in increased expression of TBX21 mRNA
CTD
PMID:24184165
NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
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Tcea3
transcription elongation factor A3
decreases expression
ISO
Azathioprine results in decreased expression of TCEA3 mRNA
CTD
PMID:22623647
NCBI chr 5:148,476,941...148,509,452
Ensembl chr 5:148,476,941...148,509,448
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Tceal1
transcription elongation factor A like 1
decreases expression
ISO
Azathioprine results in decreased expression of TCEAL1 mRNA
CTD
PMID:22623647
NCBI chr X:100,058,485...100,060,439
Ensembl chr X:100,058,132...100,060,551
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Tcf19
transcription factor 19
decreases expression
ISO
Azathioprine results in decreased expression of TCF19 mRNA
CTD
PMID:22623647
NCBI chr20:3,218,756...3,222,861
Ensembl chr20:3,218,693...3,223,271
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Tet1
tet methylcytosine dioxygenase 1
decreases expression
ISO
Azathioprine results in decreased expression of TET1 mRNA
CTD
PMID:22623647
NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052
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Tex261
testis expressed 261
increases expression
ISO
Azathioprine results in increased expression of TEX261 mRNA
CTD
PMID:21621594
NCBI chr 4:116,253,547...116,260,730
Ensembl chr 4:116,244,600...116,260,253
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Tex9
testis expressed 9
decreases expression
ISO
Azathioprine results in decreased expression of TEX9 mRNA
CTD
PMID:22623647
NCBI chr 8:73,168,519...73,213,935
Ensembl chr 8:73,177,810...73,214,261
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Tfdp1
transcription factor Dp-1
decreases expression
ISO
Azathioprine results in decreased expression of TFDP1 mRNA
CTD
PMID:22623647
NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
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Tfe3
transcription factor binding to IGHM enhancer 3
increases expression
ISO
Azathioprine results in increased expression of TFE3 mRNA
CTD
PMID:22623647
NCBI chr X:14,729,547...14,742,830
Ensembl chr X:14,729,550...14,742,571
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Tgfb1
transforming growth factor, beta 1
increases expression
ISO
Azathioprine results in increased expression of TGFB1 mRNA
CTD
PMID:22623647
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfb1i1
transforming growth factor beta 1 induced transcript 1
increases expression
ISO
Azathioprine results in increased expression of TGFB1I1 mRNA
CTD
PMID:22623647
NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
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Tgfbr3
transforming growth factor beta receptor 3
decreases expression
ISO
Azathioprine results in decreased expression of TGFBR3 mRNA
CTD
PMID:22623647
NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
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Thbs2
thrombospondin 2
increases expression
ISO
Azathioprine results in increased expression of THBS2 mRNA
CTD
PMID:19192274
NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
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Thop1
thimet oligopeptidase 1
increases expression
ISO
Azathioprine results in increased expression of THOP1 mRNA
CTD
PMID:22623647
NCBI chr 7:8,632,911...8,645,339
Ensembl chr 7:8,632,916...8,645,275
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
ISO
Azathioprine results in increased expression of TIMP1 mRNA
CTD
PMID:22623647
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Tk1
thymidine kinase 1
decreases expression
ISO
Azathioprine results in decreased expression of TK1 mRNA
CTD
PMID:22623647
NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
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Tlr2
toll-like receptor 2
increases expression decreases expression
ISO
Azathioprine results in increased expression of TLR2 mRNA Azathioprine results in decreased expression of TLR2 mRNA
CTD
PMID:19192274 PMID:24184165
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
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Tlr4
toll-like receptor 4
increases expression
ISO
Azathioprine results in increased expression of TLR4 mRNA
CTD
PMID:24184165
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tmc6
transmembrane channel like 6
increases expression
ISO
Azathioprine results in increased expression of TMC6 mRNA
CTD
PMID:22623647
NCBI chr10:102,982,059...102,999,509
Ensembl chr10:102,971,229...102,998,960
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Tmc7
transmembrane channel-like 7
increases expression
ISO
Azathioprine results in increased expression of TMC7 mRNA
CTD
PMID:22623647
NCBI chr 1:172,853,531...172,905,796
Ensembl chr 1:172,854,658...172,905,824
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Tmc8
transmembrane channel-like 8
increases expression
ISO
Azathioprine results in increased expression of TMC8 mRNA
CTD
PMID:22623647
NCBI chr10:103,000,038...103,010,601
Ensembl chr10:102,998,402...103,010,590
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Tmem140
transmembrane protein 140
increases expression
ISO
Azathioprine results in increased expression of TMEM140 mRNA
CTD
PMID:22623647
NCBI chr 4:63,536,477...63,547,478
Ensembl chr 4:63,536,168...63,548,455
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Tmem170b
transmembrane protein 170B
decreases expression
ISO
Azathioprine results in decreased expression of TMEM170B mRNA
CTD
PMID:22623647
NCBI chr17:23,131,151...23,169,946
Ensembl chr17:23,131,456...23,170,248
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Tmem237
transmembrane protein 237
decreases expression
ISO
Azathioprine results in decreased expression of TMEM237 mRNA
CTD
PMID:22623647
NCBI chr 9:60,533,348...60,569,253
Ensembl chr 9:60,535,233...60,572,567
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Tmpo
thymopoietin
decreases expression
ISO
Azathioprine results in decreased expression of TMPO mRNA
CTD
PMID:22623647
NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
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Tmt1a
thiol methyltransferase 1A
decreases expression
ISO
Azathioprine results in decreased expression of TMT1A mRNA
CTD
PMID:22623647
NCBI chr 7:131,452,099...131,460,154
Ensembl chr 7:131,451,641...131,460,154
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Tnf
tumor necrosis factor
increases expression multiple interactions
ISO
Azathioprine results in increased expression of TNF protein [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Azathioprine; Azathioprine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein] Azathioprine results in increased expression of TNF mRNA
CTD
PMID:19362101 PMID:19584951 PMID:24184165 PMID:36416909
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip2
TNF alpha induced protein 2
decreases expression
ISO
Azathioprine results in decreased expression of TNFAIP2 mRNA
CTD
PMID:19192274
NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
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Tnfrsf12a
TNF receptor superfamily member 12A
increases expression
ISO
Azathioprine results in increased expression of TNFRSF12A mRNA
CTD
PMID:22623647
NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
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Tnfrsf19
TNF receptor superfamily member 19
decreases expression
ISO
Azathioprine results in decreased expression of TNFRSF19 mRNA
CTD
PMID:22623647
NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795
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Tnfrsf1a
TNF receptor superfamily member 1A
increases expression
ISO
Azathioprine results in increased expression of TNFRSF1A mRNA
CTD
PMID:22623647
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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Top2a
DNA topoisomerase II alpha
decreases expression
ISO
Azathioprine results in decreased expression of TOP2A mRNA
CTD
PMID:22623647
NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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Tp53
tumor protein p53
increases expression increases mutagenesis
ISO
Azathioprine results in increased expression of TP53 protein Azathioprine results in increased mutagenesis of TP53 gene
CTD
PMID:14961032 PMID:17979968
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tpmt
thiopurine S-methyltransferase
affects activity affects metabolic processing affects response to substance
ISO
Azathioprine affects the activity of TPMT protein TPMT protein affects the metabolism of Azathioprine TPMT gene affects the susceptibility to Azathioprine; TPMT gene polymorphism affects the susceptibility to Azathioprine; TPMT gene SNP affects the susceptibility to Azathioprine; TPMT polymorphism affects the susceptibility to Azathioprine; TPMT promoter polymorphism affects the susceptibility to Azathioprine
CTD
PMID:12168480 PMID:12269967 PMID:12509611 PMID:14505127 PMID:15167706 PMID:15349717 PMID:15352906 PMID:15571267 PMID:15792824 PMID:16044099 PMID:16431304 PMID:17206640 PMID:17919375 PMID:18250137 PMID:19048245 PMID:19229528 PMID:19695401 PMID:20027160 PMID:20970225 PMID:20972624 PMID:21961091 PMID:22535280 More...
NCBI chr17:17,644,088...17,662,709
Ensembl chr17:17,644,173...17,662,709
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Tpx2
TPX2, microtubule nucleation factor
decreases expression
ISO
Azathioprine results in decreased expression of TPX2 mRNA
CTD
PMID:22623647
NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
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Tra2a
transformer 2 alpha
decreases expression
ISO
Azathioprine results in decreased expression of TRA2A mRNA
CTD
PMID:22623647
NCBI chr 4:78,220,838...78,239,737
Ensembl chr 4:78,220,883...78,239,712
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Trib1
tribbles pseudokinase 1
increases expression
ISO
Azathioprine results in increased expression of TRIB1 mRNA
CTD
PMID:22623647
NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
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Trib3
tribbles pseudokinase 3
increases expression
ISO
Azathioprine results in increased expression of TRIB3 mRNA
CTD
PMID:22623647
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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Trip13
thyroid hormone receptor interactor 13
decreases expression
ISO
Azathioprine results in decreased expression of TRIP13 mRNA
CTD
PMID:22623647
NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074
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Tsc2
TSC complex subunit 2
multiple interactions
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Azathioprine promotes the reaction [MAPK1 protein binds to TSC2 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Azathioprine promotes the reaction [MAPK3 protein binds to TSC2 protein]]; Azathioprine promotes the reaction [MAPK1 protein binds to TSC2 protein]; Azathioprine promotes the reaction [MAPK3 protein binds to TSC2 protein]
CTD
PMID:23958494
NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951
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Ttk
Ttk protein kinase
decreases expression
ISO
Azathioprine results in decreased expression of TTK mRNA
CTD
PMID:22623647
NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
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Tuba1b
tubulin, alpha 1B
decreases expression
ISO
Azathioprine results in decreased expression of TUBA1B mRNA
CTD
PMID:22623647
NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186
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Tubb1
tubulin, beta 1 class VI
decreases expression
ISO
Azathioprine results in decreased expression of TUBB1 mRNA
CTD
PMID:22623647
NCBI chr 3:163,247,990...163,257,460
Ensembl chr 3:163,247,967...163,256,063
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Tubb4b
tubulin, beta 4B class IVb
decreases expression
ISO
Azathioprine results in decreased expression of TUBB4B mRNA
CTD
PMID:22623647
NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
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Tubb5
tubulin, beta 5 class I
decreases expression
ISO
Azathioprine results in decreased expression of TUBB mRNA
CTD
PMID:22623647
NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
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Tusc3
tumor suppressor candidate 3
increases expression
ISO
Azathioprine results in increased expression of TUSC3 mRNA
CTD
PMID:22623647
NCBI chr16:53,196,195...53,345,241
Ensembl chr16:53,196,195...53,344,781
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Txndc16
thioredoxin domain containing 16
decreases expression
ISO
Azathioprine results in decreased expression of TXNDC16 mRNA
CTD
PMID:22623647
NCBI chr15:18,351,688...18,425,833
Ensembl chr15:18,351,694...18,425,722
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Txnip
thioredoxin interacting protein
increases expression
ISO
Azathioprine results in increased expression of TXNIP mRNA
CTD
PMID:19192274
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Txnrd1
thioredoxin reductase 1
increases expression
ISO
Azathioprine results in increased expression of TXNRD1 mRNA
CTD
PMID:22623647
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Tyms
thymidylate synthetase
decreases expression
ISO
Azathioprine results in decreased expression of TYMS mRNA
CTD
PMID:22623647
NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
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Ubd
ubiquitin D
decreases expression
ISO
Azathioprine results in decreased expression of UBD mRNA
CTD
PMID:22623647
NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639 Ensembl chr20:1,385,864...1,408,639
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Ube2c
ubiquitin-conjugating enzyme E2C
decreases expression
ISO
Azathioprine results in decreased expression of UBE2C mRNA
CTD
PMID:22623647
NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
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Ube2t
ubiquitin-conjugating enzyme E2T
decreases expression
ISO
Azathioprine results in decreased expression of UBE2T mRNA
CTD
PMID:22623647
NCBI chr13:46,403,352...46,413,854
Ensembl chr13:46,403,375...46,414,835
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Ung
uracil-DNA glycosylase
decreases expression
ISO
Azathioprine results in decreased expression of UNG mRNA
CTD
PMID:22623647
NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206
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Upp1
uridine phosphorylase 1
increases expression
ISO
Azathioprine results in increased expression of UPP1 mRNA
CTD
PMID:22623647
NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462
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Usp35
ubiquitin specific peptidase 35
increases expression
ISO
Azathioprine results in increased expression of USP35 mRNA
CTD
PMID:22623647
NCBI chr 1:151,626,195...151,649,926
Ensembl chr 1:151,626,196...151,650,015
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Vav1
vav guanine nucleotide exchange factor 1
increases expression
ISO
Azathioprine results in increased expression of VAV1 protein
CTD
PMID:12697733
NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937
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Vnn1
vanin 1
increases expression
ISO
Azathioprine results in increased expression of VNN1 mRNA
CTD
PMID:22623647
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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Vrk1
VRK serine/threonine kinase 1
decreases expression
ISO
Azathioprine results in decreased expression of VRK1 mRNA
CTD
PMID:22623647
NCBI chr 6:124,914,770...124,981,508
Ensembl chr 6:124,914,855...124,981,436
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Vsnl1
visinin-like 1
decreases expression
ISO
Azathioprine results in decreased expression of VSNL1 mRNA
CTD
PMID:22623647
NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479
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Wdr45
WD repeat domain 45
increases expression
ISO
Azathioprine results in increased expression of WDR45 mRNA
CTD
PMID:22623647
NCBI chr X:14,776,280...14,782,202
Ensembl chr X:14,776,293...14,782,202
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Zfand2a
zinc finger AN1-type containing 2A
increases expression
ISO
Azathioprine results in increased expression of ZFAND2A mRNA
CTD
PMID:22623647
NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677
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Zfp362
zinc finger protein 362
decreases expression
ISO
Azathioprine results in decreased expression of ZNF362 mRNA
CTD
PMID:22623647
NCBI chr 5:141,119,073...141,153,304
Ensembl chr 5:141,119,898...141,156,716
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Zfp385b
zinc finger protein 385B
decreases expression
ISO
Azathioprine results in decreased expression of ZNF385B mRNA
CTD
PMID:22623647
NCBI chr 3:62,355,182...62,640,417
Ensembl chr 3:62,355,196...62,640,510
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Zfp746
zinc finger protein 746
increases expression
ISO
Azathioprine results in increased expression of ZNF746 mRNA
CTD
PMID:22623647
NCBI chr 4:77,055,008...77,078,968
Ensembl chr 4:77,055,008...77,078,897
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Zg16b
zymogen granule protein 16B
increases expression
ISO
Azathioprine results in increased expression of ZG16B mRNA
CTD
PMID:22623647
NCBI chr10:12,970,888...12,984,170
Ensembl chr10:12,979,020...12,983,572
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Zwilch
zwilch kinetochore protein
decreases expression
ISO
Azathioprine results in decreased expression of ZWILCH mRNA
CTD
PMID:22623647
NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916
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Zwint
ZW10 interacting kinetochore protein
decreases expression
ISO
Azathioprine results in decreased expression of ZWINT mRNA
CTD
PMID:22623647
NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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