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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:quinaprilat
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Accession:CHEBI:140296 term browser browse the term
Definition:A dicarboxylic acid resulting from the hydrolysis of the ethyl ester group of quinapril to give the corresponding dicarboxylic acid. The active angiotensin-converting enzyme inhibitor (ACE inhibitor) of the prodrug quinapril.
Synonyms:exact_synonym: (3S)-2-{N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
 related_synonym: CI 928;   CI928;   CL-928;   Formula=C23H26N2O5;   InChI=1S/C23H26N2O5/c1-15(24-19(22(27)28)12-11-16-7-3-2-4-8-16)21(26)25-14-18-10-6-5-9-17(18)13-20(25)23(29)30/h2-10,15,19-20,24H,11-14H2,1H3,(H,27,28)(H,29,30)/t15-,19-,20-/m0/s1;   InChIKey=FLSLEGPOVLMJMN-YSSFQJQWSA-N;   SMILES=C1C2=C(C[C@H](N1C([C@@H](N[C@H](C(O)=O)CCC=3C=CC=CC3)C)=O)C(O)=O)C=CC=C2;   quinaprilate;   quinaprilatum
 xref: CAS:82768-85-2;   Chemspider:97106;   HMDB:HMDB0042005;   KEGG:C21540;   KEGG:D03773
 xref_mesh: MESH:C054501
 xref: PMID:11300367;   PMID:11422007;   PMID:11824807;   PMID:12698173;   PMID:12808303;   PMID:15223904;   PMID:19016233;   PMID:19135197;   PMID:19761414;   PMID:21083190;   PMID:24175935;   PMID:9336392;   Reaxys:5653070;   Wikipedia:Quinaprilat



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quinaprilat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a1 solute carrier family 15 member 1 multiple interactions ISO quinaprilat inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545
JBrowse link
G Slc15a2 solute carrier family 15 member 2 multiple interactions ISO
EXP
quinaprilat inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      application 19729
        pharmaceutical 19565
          drug 19565
            cardiovascular drug 8621
              vasodilator agent 6006
                quinaprilat 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      carboxylic acid 18646
                                        carboacyl group 17727
                                          univalent carboacyl group 17727
                                            carbamoyl group 17575
                                              carboxamide 17575
                                                tertiary carboxamide 834
                                                  quinaprilat 2
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