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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:quinaprilat
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Accession:CHEBI:140296 term browser browse the term
Definition:A dicarboxylic acid resulting from the hydrolysis of the ethyl ester group of quinapril to give the corresponding dicarboxylic acid. The active angiotensin-converting enzyme inhibitor (ACE inhibitor) of the prodrug quinapril.
Synonyms:exact_synonym: (3S)-2-{N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
 related_synonym: CI 928;   CI928;   CL-928;   Formula=C23H26N2O5;   InChI=1S/C23H26N2O5/c1-15(24-19(22(27)28)12-11-16-7-3-2-4-8-16)21(26)25-14-18-10-6-5-9-17(18)13-20(25)23(29)30/h2-10,15,19-20,24H,11-14H2,1H3,(H,27,28)(H,29,30)/t15-,19-,20-/m0/s1;   InChIKey=FLSLEGPOVLMJMN-YSSFQJQWSA-N;   SMILES=C1C2=C(C[C@H](N1C([C@@H](N[C@H](C(O)=O)CCC=3C=CC=CC3)C)=O)C(O)=O)C=CC=C2;   quinaprilate;   quinaprilatum
 xref: CAS:82768-85-2;   Chemspider:97106;   HMDB:HMDB0042005;   KEGG:C21540;   KEGG:D03773
 xref_mesh: MESH:C054501
 xref: PMID:11300367;   PMID:11422007;   PMID:11824807;   PMID:12698173;   PMID:12808303;   PMID:15223904;   PMID:19016233;   PMID:19135197;   PMID:19761414;   PMID:21083190;   PMID:24175935;   PMID:9336392;   Reaxys:5653070;   Wikipedia:Quinaprilat



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quinaprilat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a1 solute carrier family 15 member 1 multiple interactions ISO quinaprilat inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545
JBrowse link
G Slc15a2 solute carrier family 15 member 2 multiple interactions ISO
EXP
quinaprilat inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19715
    role 19690
      application 19522
        pharmaceutical 19409
          drug 19409
            cardiovascular drug 8452
              vasodilator agent 5844
                quinaprilat 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19715
    subatomic particle 19713
      composite particle 19713
        hadron 19713
          baryon 19713
            nucleon 19713
              atomic nucleus 19713
                atom 19713
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19606
                        carbon atom 19603
                          organic molecular entity 19603
                            organic group 18792
                              organic divalent group 18777
                                organodiyl group 18777
                                  carbonyl group 18743
                                    carbonyl compound 18743
                                      carboxylic acid 18443
                                        carboacyl group 17599
                                          univalent carboacyl group 17599
                                            carbamoyl group 17435
                                              carboxamide 17435
                                                tertiary carboxamide 224
                                                  quinaprilat 2
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